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Epidemiological profile of alcoholic liver disease hospital admissions in a Latin American country over a 10-year period

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World Journal of Hepatology 2020年第5期12卷 230-238页

作者： Andre Castro Lyra Lorena Mascarenhas Carneiro de Almeida Yukari Figueroa Mise Lourianne nascimento Cavalcante Gastro-Hepatology Service Hospital Sao RafaelSalvadorBahia 41253-190Brazil Gastro-Hepatology Service Hospital Universitario Prof.Edgard SantosFederal University of BahiaSalvadorBahia 40301-155Brazil de Saude Coletiva-Federal University of Bahia SalvadorBahia 40110-040Brazil

BACKGROUND Alcoholic liver disease(ALD)is a major cause of chronic liver disease *** To describe the epidemiological profile and mortality rates of patients with ALD admitted to public hospitals in different regions of Brazil from 2006 to *** This is a descriptive study that evaluated aggregate data from the five Brazilian geographic *** A total of 160093 public hospitalizations for ALD were *** was a 34.07%increase in the total number of admissions over 10 years,from 12879 in 2006 to 17267 in *** region with the highest proportion(49.01%)of ALD hospitalizations was Southeast(n=78463).The North region had the lowest absolute number of patients throughout the study period,corresponding to 3.9%of the total(n=6242).There was a 24.72%increase in the total number of ALD deaths between 2006 and *** found that the age group between 50 and 59 years had the highest proportion of both hospitalizations and deaths:28.94%(n=46329)of total hospital admissions and 29.43%(n=28864)of all *** were more frequently hospitalized than women and had the highest proportions of deaths in all *** coefficient rates increased over the years,and simple linear regression analysis indicated a statistically significant upward trend in this mortality(R^2=0.744).CONCLUSION Our study provides a landscape of the epidemiological profile of public hospital admissions due to ALD in *** detected an increase in the total number of admissions and deaths due to ALD over 10 years.

关键词： Alcoholic liver disease Epidemiology Mortality Liver Cirrhosis Hospital admissions

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The REMO Ocean Data Assimilation System into HYCOM(RODAS_H):General Description and Preliminary Results

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Atmospheric and Oceanic Science Letters 2014年第5期7卷 464-470页

作者： Clemente Augusto Souza TANAJURA Alex Novaes SANTANA Davi MIGNAC Leonardo nascimento LIMA Konstantin BELYAEV XIE Ji-Ping Physics Institute Federal University of Bahia (UFBA) Salvador 40170-280 Brazil Oceanographic Modeling and Observation Network (REMO) Center for Research in Geophysics and Geology Federal University of Bahia (UFBA) Salvador 40170-280 Brazil Ocean Sciences Department University of California Santa Cruz (UCSC) USA Graduate Program in Geophysics Federal University of Bahia (UFBA) Salvador Brazil Shirshov Institute of Oceanology Russian Academy of Sciences (SHIRSHOV/RAS) Moscow Russia Institute of Atmospheric Physics(IAP) Chinese Academy of Sciences (CAS)

The first version of the Brazilian Oceano- graphic Modeling and Observation Network （REMO） ocean data assimilation system into the Hybrid Coordi- nate Ocean Model （HYCOM）（RODAS H） has recently been constructed for research and operational purposes. The system is based on a multivariate Ensemble Optimal Interpolation （EnOI） scheme and considers the high fre- quency variability of the model error co-variance matrix. The EnOl can assimilate sea surface temperature （SST）, satellite along-track and gridded sea level anomalies （SLA）, and vertical profiles of temperature （T） and salinity （S） from Argo. The first observing system experiment was carried out over the Atlantic Ocean （78°S-50°N, 100°W-20°E） with HYCOM forced with atmospheric reanalysis from 1 January to 30 June 2010. Five integra- tions were performed, including the control run without assimilation. In the other four, different observations were assimilated： SST only （A SST）; Argo T-S profiles only （AArgo）; along-track SLA only （A_SLA）; and all data employed in the previous runs （A_All）. The A_SST, A_Argo, and A_SLA runs were very effective in improv- ing the representation of the assimilated variables, but they had relatively little impact on the variables that were not assimilated. In particular, only the assimilation of S was able to reduce the deviation of S with respect to ob- servations. Overall, the A_All run produced a good analy- sis by reducing the deviation of SST, T, and S with respect to the control run by 39%, 18%, and 30%, respectively, and by increasing the correlation of SLA by 81%.

关键词： ocean data assimilation ensemble optimalinterpolation observing system experiment HYCOM Atlantic Ocean

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Experimental statistic design applied for obtaining Zn:xCe by microwave-assisted hydrothermal method with photocatalytic property

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Journal of Advanced Ceramics 2016年第2期5卷 103-110页

作者： Y.F.GOMES A.K.FREITAS R.M.nascimento M.R.D.BOMIO C.A.PASKOCIMAS F.V.MOTTA Departamento de Engenharia de Materiais Universidade Federal do Rio Grande do Norte 59078-900 Natal/RN Av.Sen.Salgado Filho 3000 CEP 59072-970 Brazil

In this study, the nanostructures of pure ZnO and ZnO:xCe3+ were prepared using statistic design—factorial design 3(3−1)−3-level and mixed-level factorials and fractional with replicates in the central point, totaling 11 experiments. The experiments were performed using the microwave-assisted hydrothermal (MAH) method with Ce3+ concentration of 2 and 4 mol% at 60, 110, and 160 °C for 10, 20, and 30 min. X-ray diffraction (XRD), scanning electron microscopy (SEM), and optical diffuse reflectance were used to characterize the products. The fractional factorial design indicated the optimal design area, and the studies were continued by ridge analysis. The analysis of variance (ANOVA), the Pareto, and the model adjusted to the conditions proposed in this study due to the determination coefficient of 99.9%, variance (R 2), and response surface generated were satisfactory, thus having an optimization in the process of obtaining ZnO doped with Ce.

关键词： hydrothermal ZnO cerium photocatalytic activity factorial design 3(3-1)

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Environmental and Durability Perspective of the Use of Curaua Fiber Treated in Mortars

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Journal of Renewable Materials 2022年第9期10卷 2409-2429页

作者： Afonso R.G.de Azevedo Marcelo nascimento Dirlane do Carmo Markssuel T.Marvila Gustavo de C.Xavier Sergio Neves Monteiro UENF-State University of the Northern Rio de Janeiro LECIV-Civil Engineering LaboratoryCampos dos GoytacazesBrazil UFF-Federal Fluminense University TER-Department of Agricultural EngineeringNiteróiBrazil UENF-State University of the Northern Rio de Janeiro LAMAV-Advanced Materials LaboratoryCampos dos GoytacazesBrazil IME-Military Institute of Engineering Department of Materials ScienceRio de JaneiroBrazil

The use of natural lignocellulosic fibers(NLFs)as a reinforcement mechanism for cementitious composites,such as mortar,has been investigated in the last ***,their application has often been restricted to technological evaluation research.A NLF with great potential the curaua,which after treatment with NaOH solution,proved to be technologically feasible for mortars reinforcement based on cement and *** objective of this research was the comparative evaluation between a traditional mortar,based on cement and lime,with 1:1:6:0.8 ratio of cement:lime:sand:water,and a modified mortar with addition of 2 wt.%treated curaua fiber in cement mass by evaluating environmental and durability *** a curing time for 28 days,environmental assessments were carried out and durability methodologies were *** tests performed were:(i)attack by chlorides and sulfate,(ii)the wetting and drying cycles,and(iii)slake durability *** results showed that the mortar with the addition of curaua fiber presented a similar behavior to the reference mixture,both in terms of environmental and durability *** modified mortar is able to be used in internal and external environments,the latter with some ***,it also contributes to the promotion of sustainable use of curaua fiber.

关键词： Natural lignocellulosic fibers curaua mortar durability environmental aspects

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Considerations for Erythema Nodosum Leprosum, with Emphasis on Its Oral Manifestations

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Advances in Infectious Diseases 2013年第1期3卷 35-43页

作者： Antonio Carlos Vinhas Roberto Meyer nascimento Immunology Institute of Sciences and Health (ICS-UFBA) Salvador Brazil Interactive Processes in Organs and Systems Program Concentration Area in Biosafety (PPGORGSISTEM) Salvador Brazil

Leprosy is an infectious disease caused by Mycobacterium leprae, transmitted from person to person through contact among susceptible untreated patients. It presents a broad clinical spectrum which is related to the host’s ability to mount a specific immune response. The lesions caused by the proliferation of Mycobacterium leprae (M. leprae) were significantly reduced in recent years with the early detection of new cases. Because they are less evident and/or study, maxillofacial injuries and the oral mucosa may reveal important details about the transmissibility and immunopathogenesis of leprosy. This article was based on a literature to verify an interrelation between oral manifestations in virchowian patients and immuno-pathological factors. Association between the infection of oral mucosa and some pathological findings as well as the participation of the local immune response in protection against the disease are research topics still not fully exploited.

关键词： Leprosy Hansen Disease Oral manifestation

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Urban development and industrialization impacts on semiaquatic bugs diversity: A case study in eastern Amazonian streams

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Water Biology and Security 2022年第4期1卷 43-50页

作者： Erlane Jose Cunha Gabriel Martins Cruz Ana Paula Justino Faria John nascimento De Oliveira Leandro Juen Programa de Pos-graduaçao em Ecologia Universidade Federal do Para e Embrapa Amazonia OrientalRua Augusto CorreiaNº1Bairro GuamaCEP66075-110BelemParaBrazil Programa de Pos-graduaçao em Zoologia Universidade Federal do Para/Museu Paraense Emílio GoeldiRua Augusto CorreiaNº1Bairro GuamaCEP66075-110BelemParaBrazil Laboratorio de Ecologia e Conservaçao Universidade Federal do Para/Rua Augusto CorreiaNº1Bairro GuamaCEP66075-110BelemParaBrazil Programa de Pos-Graduaçao em Agricultura e Ambiente Laboratorio de Ciencias Ambientais e BiodiversidadeUniversidade Estadual do MaranhaoSao LuísBrazil Hydro Alunorte Rodovia PA–481km 12Distrito de MurucupiCEP68447-000BarcarenaParaBrazil

Landscape changes have caused the decline of biodiversity and affected the integrity of aquatic *** this study,we assessed the influence of industrialization associated with urban development on aquatic environments and the biodiversity of semiaquatic bugs(Gerromorpha)at different scales(water quality,habitat,and landscape).Using the simple buffer method,we evaluated nine streams assessing water quality variables,habitat structure,and linear features(radius¼300 m,length¼600 m)for the percentage of land use and land *** results found that species composition of Gerromorpha was mainly affected by primary forest cover,habitat integrity,leaves substrate,and water temperature(29%explanation),and the species richness was mostly influenced by the habitat integrity index(HII)and phosphorus *** model that best explained the variation in species richness showed a positive relationship with phosphorus concentrations and HII(43%variation).Therefore,our results show that those human activities are the main factors altering aquatic biodiversity from local to regional ***,the retention of riparian forests–even in urban and industrialized areas–can maintain the diversity of semiaquatic insect species by providing suitable environments for the habitat,feeding,and reproductive requirements of these aquatic ***,our results also show that the management of riparian vegetation in urban areas and industrial complexes promotes aquatic biodiversity conservation in regions under development in the Amazon.

关键词： Aquatic insects Biodiversity conservation Gerromorpha Stream conservation Land use

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World Journal of Clinical Cases 2021年第17期9卷 4123-4132页

作者： Rodrigo nascimento Pinheiro Samantha Mucci Renato Morato Zanatto Olavo Magalhães Picanço Junior Alexandre Ferreira Oliveira Gaspar de Jesus Lopes Filho Surgical Oncology Service Surgical Oncology Residency and Academic League of OncologyFederal District Base HospitalBrasília 70330-150Distrito FederalBrazil Department of Psychiatry Federal University of São PauloPaulista School of Medicine(UNIFESP-EPM)São Paulo 04024-002São PauloBrazil Department of Surgical Oncology Amaral Carvalho Cancer HospitalJaú17210-070São PauloBrazil Department of Surgical Oncology Federal University of AmapáMacapá68900-073AmapáBrazil Department of Surgery Juiz de Fora Federal UniversityJuiz de Fora 36036-110Minas GeraisBrazil Postgraduate Program in Interdisciplinary Surgical Science Federal University of São PauloPaulista School of Medicine(UNIFESP-EPM)São Paulo 04024-002São PauloBrazil

In Brazil,gastric cancer is the third most common type of cancer among men and fifth among women,with an estimated 13360 new cases among men and 7870 among women each year during the 2020-2022 *** study presents reflections and attempts to add knowledge to the theme of quality of life(QoL)in patients with gastric adenocarcinoma and describes some of its characteristics in three regions of Brazil,with an evaluation of the disease’s impacts in various dimensions of life,as reported by the patients *** performed a narrative review of the literature and a data analysis of studies on QoL in Brazilian patients treated for gastric adenocarcinoma from three different cities in three geographic regions:Brasília(the midwest),Jaú(the southeast),and Macapá(the north).

关键词： Quality of life Gastric cancer Gastrectomy Stomach cancer Stomach neoplasms Gastric neoplasms

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Treatability studies of naphthalene in soil,water and air with persulfate activated by iron(Ⅱ)

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Journal of Environmental Sciences 2020年第4期32卷 67-77页

作者： Gabriela P.Mendes Vivian M.A.Magalhaes Lélia C·R·Soares Rayanne M.Aranha Claudio A.O.nascimento Marilda M.G.R.Vianna Osvaldo Chiavone-Filho Department of Chemical Engineering University of Sao PauloSPf 05508-000Brazil Department of Chemical Engineering Federal University of Rio Grande Do NorteNatalRN59072-970Brazil

Chemical oxidation was applied to an artificially contaminated soil with naphthalene(NAP).Evaluation of NAP distribution and mass reduction in soil,water and air phases was carried out through mass *** of NAP distribution and mass reduction in soil,water and air phases was carried out through mass *** importance of the air phase analysis was emphasized by demonstrating how NAP behaves in a sealed system over a 4 hr reaction *** of Experiments method was applied to the following variables:sodium persulfate concentration[SP],ferrous sulfate concentration[FeS04],and *** system operated with a prefixed solid to liquid ratio of 1:*** following conditions resulted in optimum NAP removal[SP]=18.37 g/L,[FeSO4]=4.25 g/L and pH=*** the end of the 4 hr reaction,62%of NAP was *** the soil phase,the chemical oxidation reduced the NAP concentration thus achieving levels which comply with Brazilian and USA environmental *** the NAP partitioning view,the monitoring of each phase allowed the variabilities assessment over the process,refining the knowledge of mass *** on NAP distribution in the system,this study demonstrates the importance of evaluating the presence of semi-volatile and volatile organic compounds in the air phase during remediation,so that there is greater control of the system as to the distribution and presence of the contaminant in the *** results highlight the importance of treating the contaminant in all its phases at the contaminated site.

关键词： Chemical oxidation Phase distribution Degradation kinetics PAH Soil remediation Mass balance

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Conocarpus erectus L., a plant with a high content of structural sugars, ions and phenolic compounds, shows antioxidant and antimicrobial properties promoted by different organic fractions

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Asian Pacific Journal of Tropical Biomedicine 2018年第9期8卷 463-470页

作者： Dayane Kelly Dias do nascimento Santos Weslley Henrique de Oliveira Melo Anastassia Mariáh Nunes de Oliveira Lima Iranildo Joseda Cruz Filho Glaucia Manoella de Souza Lima Tulio Diego da Silva Maiara Celine de Moura Marcia Silva do nascimento Ana Maria Souto Maior Thiago Henrique Napoleao Cristiane Moutinho Lagos de Melo Department of Biochemistry Biosciences Centre Federal University of Pernambuco Department of Antibiotics Biosciences Centre Federal University of Pernambuco Center of Strategic Technologies of the Northeast

Objective: To evaluate the structural and chemical composition of plant and the antioxidant and antimicrobial activities promoted by hexanic, ethanolic and ethyl acetate fractions obtained from leaves of Conocarpus ***: Organic fractions were characterized through UPLC-MS and *** potential was performed through DPPH and molybdenum phosphate *** and antifungal assays were performed in accordance with Clinical and Laboratory Standards Institute ***: The obtained biomass of Conocarpus erectus leaves showed the high presence of glucose(0.45 g/L), cellulose(28.69%), Na(55.126 μg/L) and K(31.163 μg/L).We identified seven compounds in the hexanic and ethyl acetate fractions, and eight compounds in ethanolic ***, phenolic compounds are prevalent in all organic fractions with values of(10.04 ± 0.24),(221.26 ± 1.84),(340.53 ± 0.84) mg/g GAE to hexanic, ethyl acetate and ethanolic fraction, *** results showed a high potential in ethyl acetate fraction(71.82 ± 6.87)% and(10.89 ± 0.05)% in DPPH and molybdenum phosphate techniques, *** ethanolic fraction showed moderate bacteriostatic and bactericidal activity against Staphylococcus aureus and presented a high fungistatic potential for all Candida species ***: Organic fractions obtained from leaves of Conocarpus erectus present antimicrobial and antioxidant properties, and these findings contribute to scientific information for the effectiveness on use of this plant in the development of a phytotherapic compound.

关键词： Combretaceae Phenolic compounds Antimicrobial activity Antioxidant

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cAMP:A second messenger involved in the mechanism of midgut alkalinization in Lutzomyia longipalpis

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Insect Science 2022年第4期29卷 1059-1070页

作者： Denise Barguil Nepomuceno Grasielle Caldas D’Ávila Pessoa Leonardo Barbosa Koerich Marcos Horácio Pereira Mauricio Roberto Viana Sant'Anna Ricardo nascimento Araújo Nelder Figueiredo Gontijo Laboratório de Fisiologia de Insetos Hematófagos Departamento de Parasitologia/ICBUniversidade Federal de Minas GeraisBelo HorizonteMGBrazil

The sand fly Lutzomyia longipalpis is the main vector of Leishmania infantum in the *** sand flies ingest sugar-rich solutions and blood,which are digested in the *** of nutrients is an essential function performed by digestive enzymes,which require appropriate physiological *** of the main aspects that influence enzymatic activity is the gut pH,which must be tightly *** second messengers are frequently involved in the coordination of tightly regulated physiological events,we investigated if the second messenger cAMP would participate in the process of alkalinization in the abdominal midgut of female *** midguts containing the indicator dye bromothymol-blue,cAMP stimulated the alkalinization of the midgut *** another technique based on the use of fluorescein as a pH indicator,we propose that cAMP is involved in the alkalinization of the midgut by activating HCO3-transport from the enterocyte's cytoplasm to the *** results strongly suggested that the carrier responsible for this process would be a HCO3−/Cl−antiporter located in the enterocytes’apical *** promotes the release of alkalinizing hormones in the hemolymph;however,when the enzyme adenylyl cyclase,responsible for cAMP production,was inhibited,we observed that the hemolymph from blood-fed ***’females did not stimulate midgut *** result indicated that hormone-stimulated alkalinization is mediated by *** the present study,we provide evidences that cAMP has a key role in the control of intestinal pH.

关键词： abdominal midgut alkalinization cAMP HCO_(3)^(-)/Cl^(-)antiport hormone Lulcomyia longipalpis

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