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Biomechanical diagnostics of the cornea

Eye and Vision 2020年第1期7卷 87-98页

作者： Louise Pellegrino Gomes Esporcatte marcella q.salomão Bernardo T.Lopes Paolo Vinciguerra Riccardo Vinciguerra Cynthia Roberts Ahmed Elsheikh Daniel G.Dawson Renato Ambrósio Jr Rio de Janeiro Corneal Tomography and Biomechanics Study Group Rio de JaneiroBrazil Instituto de olhos Renato Ambrósio Rua Conde de Bonfim 211/712Rio de JaneiroRJ 20520-050Brazil Department of ophthalmology Hospital São Vicente de PauloRio de JaneiroBrazil Brazilian Study Group of Artificial Intelligence and Corneal Analysis–BrAIN Rio de Janeiro&MaceióBrazil Department of ophthalmology Federal University of São PauloSão PauloBrazil Instituto Benjamin Constant Rio de JaneiroBrazil School of Engineering University of LiverpoolLiverpool L693GHUK Department of Biomedical Science Humanitas UniversityRozzanoItaly Eye Center Humanitas Clinical and Research CenterRozzanoItaly Department of ophthalmology Humanitas San Pio X HospitalMilanItaly Department of ophthalmology and Visual Science Department of Biomedical EngineeringThe Ohio State UniversityColumbusOHUSA School of Biological Science and Biomedical Engineering Beihang UniversityBeijingChina NIHR Biomedical Research Centre for ophthalmology Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of OphthalmologyLondonUK The University of Florida Department of ophthalmology GainesvilleFLUSA Department of ophthalmology Federal University the State of Rio de Janeiro(UNIRIO)Rio de JaneiroBrazil

Corneal biomechanics has been a hot topic for research in contemporary ophthalmology due to its prospective applications in diagnosis,management,and treatment of several clinical conditions,including glaucoma,elective keratorefractive surgery,and different corneal *** clinical biomechanical investigation has become of great importance in the setting of refractive surgery to identify patients at higher risk of developing iatrogenic ectasia after laser vision *** review discusses the latest developments in the detection of corneal ectatic *** developments should be considered in conjunction with multimodal corneal and refractive imaging,including Placido-disk based corneal topography,Scheimpflug corneal tomography,anterior segment tomography,spectral-domain optical coherence tomography(SD-oCT),very-high-frequency ultrasound(VHF-US),ocular biometry,and ocular wavefront *** ocular response analyzer(oRA)and the Corvis ST are non-contact tonometry systems that provide a clinical corneal biomechanical *** recently,Brillouin optical microscopy has been demonstrated to provide in vivo biomechanical *** integration of tomographic and biomechanical data into artificial intelligence techniques has demonstrated the ability to increase the accuracy to detect ectatic disease and characterize the inherent susceptibility for biomechanical failure and ectasia progression,which is a severe complication after laser vision correction.

关键词： Corneal biomechanics Corneal ectasia Corneal imaging

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