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Prognostic Factors for Mortality in Severe Traumatic Brain Injury at HGZ 46, Villahermosa, Tabasco, Period from March 1, 2021 to December 31, 2022

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Open Journal of Emergency Medicine 2024年第1期12卷 1-9页

作者： América del carmen Flores Jiménez Eduardo Guillermo Aguilar López Rafael Blanco De La vega Pérez Juan Manuel Hernández Vázquez Emergency Room at General Zone Hospital #46 (HGZ46) “Dr. Bartolomé Reynés Berezaluce” from Mexican Institute of Social Security Tabasco Mexico Intensive Care Unit at General Zone Hospital #46 (HGZ46) “Dr. Bartolomé Reynés Berezaluce” from Mexican Institute of Social Security Tabasco Mexico

Introduction: A traumatic brain injury (TBI) is caused by a forceful bump, blow, or jolt to the head or body, or by an object that pierces the skull and interrupts the normal function of the brain. Severe TBI is estimated at 73 cases per 100,000 people. The mortality of severe TBI can be reduced if a timely diagnosis and treatment of the injuries are made through prognostic factors. Objective: To determine the prognostic factors related to mortality in severe traumatic brain injury at the Hospital General de Zona No. 46. Material and Methods: Retrospective, cross-sectional and descriptive study in beneficiaries admitted to the Hospital General de Zona (HGZ) No. 46 of the Mexican Institute of Social Security (IMSS by its acronym in Spanish), with a diagnosis of severe TBI;the possible prognostic factors related to mortality of severe TBI were obtained from their records. Measures of central tendency and chi square were used for data analysis. Results: The study sample consisted of 60 subjects diagnosed with severe traumatic brain injury, of which 5 (8%) were women and 55 (92%) were men, and all 60 (100%) patients died. The average age of the sample was 26 with a standard deviation of 9 years. The variables that had a p value less than or equal to 0.05 were: Mydriasis, seizures, Hyperglycemia, Normoglycemia, Hypothermia and Hypotension. This means that these variables were associated with mortality. Conclusion: Statistical significance is demonstrated in prognostic factors of mortality in severe traumatic brain injury with p < 0.05 in the case of mydriasis, seizures, hyperglycemia, normoglycemia, hypothermia and hypotension.

关键词： Traumatic Brain Injury Prognostic Factors Mortality Severity

Digestibility,Antioxidant and Anti-Inflammatory Activities of Pecan Nutshell(Carya illioinensis)Extracts

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Journal of Renewable Materials 2022年第10期10卷 2569-2580页

作者： María Janeth Rodríguez-Roque carmen Lizette del-Toro-Sánchez Janet Madeline Chávez-Ayala Ricardo Iván González-vega Liliana Maribel Pérez-Pérez Esteban Sánchez-Chávez Nora AideéSalas-Salazar Juan Manuel Soto-Parra Rey David Iturralde-García María Antonia Flores-Córdova Facultad de Ciencias Agrotecnológicas Universidad Autónoma de ChihuahuaChihuahuaMéxico Universidad de Sonora Rosales y Niños Héroes S/NHermosilloSonMéxico Centro de Investigación en Alimentación y Desarrollo A.C.Unidad DeliciasDeliciasChihuahuaMéxico

Phenolic compounds are related to high biological activity,avoiding oxidation in food and human *** are by-products derived from the pecan nut processing that contain important amounts of phenols which biological activity must be *** research aimed to evaluate the antioxidant(DPPH,ABTS,FRAP and hemolysis)and anti-inflammatory activities of shell extracts from pecan nuts harvested during the crop production cycle 2018 and 2019,as well as the in vitro digestibility of their phenolic compounds,including *** showed that extracts from the crop production cycle 2018 obtained the highest yield,while those from 2019 contained the highest concentration of phenolic compounds,flavonoids and antioxidant capacity determined by DPPH(22.96 mmol ET),ABTS(91.55 mmol ET)and inhibition of hemolysis(92.12%).The anti-inflammatory activity exhibited an inhibition of the elastase enzyme up to 50 min and the bioaccessibility of phenolic compounds reached up to 32%.These results showed that pecan nutshell extracts are an important source of biologically active compounds,thus,they are suitable to be used as commodities in different fields such as agricultural,food and pharmaceutical *** studies must be carried out in order to elucidate the activity of nutshell extracts within in vivo systems.

关键词： Anti-inflammatory activity antioxidants digestibility shell phenolic compounds

Diversity and host assemblage of avian haemosporidians in different terrestrial ecoregions of Peru

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Current Zoology 2022年第1期68卷 27-40页

作者： Luz GARCIA-LONGORIA Jaime MURIEL Sergio MAGALLANES Zaira Hellen VILLA-GALARCE Leonila RICOPA Wilson Giancarlo INGA-DIAZ Esteban FONG Daniel VECCO Cesar GUERRA-SALDANA Teresa SALAS-RENGIFO Wendy FLORES-SAAVEDRA Kathya ESPINOZA Carlos MENDOZA Blanca SALDANA Manuel GONZALEZ-BLAZQUEZ Henry GONZALES-PINEDO Charlene LUJAN-vega Carlos Alberto del AGUILA Yessica VILCA-HERRERA Carlos Alberto PINEDA carmen REATEGUI Jorge Manuel CARDENAS-CALLIRGOS JoseAlberto IANNACONE Jorge Luis MENDOZA Ravinder NMSEHGAL Alfonso MARZAL Departamento de Anatomia Biologia Celular y ZoologiaUniversidad de ExtremaduraBadajoz E-506071Spain Molecular Ecology and Evolution Lab Department of BiologyLund UniversitySolvegatan 37SE-22362 LundSweden Instituto Pirenaico de Ecologıa-IPE(CSIC) Avda.Nuestra Senora de la Victoria 16Jaca 22700Spain DIRESA Direccion Regional de SaludLoreto 16001Peru Departamento Academico de Microbiologia y Parasitologia.Facultad de Ciencias Biologicas Universidad Nacional de la Amazonia PeruanaIquitos 16001Peru Facultad de Ciencias Agropecuarias Universidad Alas PeruanasLima 15823Peru EverGreen Institute-San Rafael Distrito de IndianaLoreto 16200Peru Observatorio de Aves Loreto(LBO) Distrito de San JuanLoreto 16008Peru Centro Urku de Estudios Amazonicos Tarapoto 22200Peru Servicio Nacional de Areas Naturales Protegidas por el Estado 15036Peru Sanidad Animal-Facultad de Zootecnia Universidad Nacional Agraria La MolinaLima 15012Peru Laboratorio de Microbiologia Facultad de Medicina Veterinaria y ZootecniaUniversidad CientUfica del SurLima 15067Peru Laboratorio de Analisis Clinico Moraleslab SAC MoralesSan Martin 22201Peru Asociacion Ecosistemas Andinos(ECOAN) Cuzco 08002Peru Pharmacology and Toxicology Graduate Group University of CaliforniaDavisDA 95616USA Global Health Initiative Wabash CollegeCrawfordsvilleIN 47933USA Facultad de Ciencias Biologicas Universidad Nacional Mayor de San MarcosLima 15081Peru Facultad de Medicina Veterinaria Universidad Nacional Hermilio ValdizanHuanuco10160Peru Asociacion Peruana de Helmintologia e Invertebrados Afines Lima 15054Peru Laboratorio de Ecologia y Biodiversidad Animal Universidad Nacional Federico VillarrealEl AgustinoLima 15007Peru Laboratorio de Invertebrados Universidad Ricardo Palma-Santiago de SurcoLima 15537Peru Department of Biology San Francisco State UniversitySan FranciscoCA 94132USA

Characterizing the diversity and structure of host–parasite communities is crucial to understandingtheir eco-evolutionary *** and related haemosporidian parasites are responsible forfitness loss and mortality in bird species ***,despite exhibiting the greatest ornithologicalbiodiversity,avian haemosporidians from Neotropical regions are quite ***,we analyze the genetic diversity of bird haemosporidian parasites(Plasmodium andHaemoproteus)in 1,336 individuals belonging to 206 bird species to explore for differences in diversityof parasite lineages and bird species across 5 well-differentiated Peruvian *** 70 different haemosporidian lineages infecting 74 bird *** showed that 25 out ofthe 70 haplotypes had not been previously ***,we also identified 81 new host–parasite interactions representing new host records for these haemosporidian *** outcomesrevealed that the effective diversity(as well as the richness,abundance,and Shannon–Weaver index)for both birds and parasite lineages was higher in Amazon basin ***,we also showed that ecoregions with greater diversity of bird species also had highparasite richness,hence suggesting that host community is crucial in explaining parasite *** parasites were found in ecoregions with lower bird diversity,implying that the abundanceand richness of hosts may shape the exploitation strategy followed by haemosporidian *** outcomes reveal that Neotropical region is a major reservoir of unidentified *** studies analyzing host distribution and specificity of these parasites inthe tropics will provide important knowledge about phylogenetic relationships,phylogeography,and patterns of evolution and distribution of haemosporidian parasites.

关键词： Amazonia avian malaria generalist parasite habitat specificity Haemoproteus Plasmodium specialist parasite

Application of the Weibull Distribution to Estimate the Volume of Water Pumping by a Windmill

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Journal of Power and Energy Engineering 2016年第9期4卷 36-51页

作者： M. Toledo Velázquez J. Herná ndez Rodrí guez M. vega del carmen F. E. Flores Murrieta G. Tolentino Eslava Laboratorio de Ingenierí a Té rmica e Hidrá ulica Aplicada (LABINTHAP) IPN-SEPI-ESIME Zacatenco Ciudad de M&eacute xico M&eacute xico Divisió n de Ciencias e Ingenierí a Laboratorio en Sistemas de Energ&iacute a Universidad de Quintana Roo Chetumal M&eacute xico

Given the steady increase in use of alternative energy sources to supply part of the energy demand of the world, and considering that Mexico has enough wind resources to produce all the electricity required by the country, in this work, it is carried out the development of a system of wind resource assessment to determine the volume of water that a windmill pumping system can provide in a specific area. To this end, it has developed a computer program for wind resource assessment by measurements of wind speed, direction, temperature, barometric pressure and relative humidity. Measuring equipments were mounted in a wind measurement tower of 10 m high, within the premises of the University of Quintana Roo which is located along the coast. Until this day, there are records over a period of five months of the variables of wind speed, wind direction, temperature, relative humidity and atmospheric pressure. These variables were used for statistical calculations using the Weibull distributions. To give a better use of the calculated data, they were applied to the evaluation of a Pumping System.

关键词： Pumping Systems Weibull Distribution Wind Energy Windmill

Myxoid Meningioma:An Example of a Rare Brain Tumour of Difficult Diagnosis

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Open Journal of Pathology 2013年第1期3卷 51-53页

作者： Javier Ortiz Maria Dolores Ludena Jesus Goncalves Sofia del carmen Angel Maillo Agustin Bullon Pathology Department Hospital Universitario de Salamanca(Complejo Hospitalario de Salamanca)SalamancaSpain Neuro-surgery Department Hospital Virgen de la Vega(Complejo Hospitalario de Salamanca)SalamancaSpain

We present a case of a Myxoid Meningioma noticed in a 43-year-old woman. The patient, who had no noteworthy medical antecedents, showed repeated focal epileptic crisis. Imaging studies (MR and CT) showed a solitary and well delimited tumour located in the frontral lobe. Once extirpated, the histological study revealed a neoplasm of myxoid and benign appearance, with elongated and uniform cells, with no atypias and a very low mitotic index. Immunohistochemisty studies (positivity for Vimentin and Epithelial Membrane Antigen, and negativity for the other markers) as well as physical and radiological examination of the patient (absence of tumours in any other location), suggested the diagnosis of a Myxoid Meningioma, which was confirmed by electron microscopy (by the presence of desmosomes). We also revise the characteristics of Myxoid Meningiomas, an absolutely exceptional primary tumour of the central nervous system.

关键词： Myxoid Meningioma Immunohistochemistry Electron Microscopy

Evolution of Pre-Columbian Metallurgy from the North of Peru Studied with a Portable Non-invasive Equipment Using Energy-Dispersive X-Ray Fluorescence

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材料科学与工程（中英文B版） 2011年第1期1卷 48-81页

作者： Roberto Cesareo Angel Bustamante D Julio Fabian S Sandra Zambrano A Walter Alva Luis Chero del carmen Espinoza C Rosendo Rodriguez R Marco Seclen F Fidel Gutierrez V E.B. Ldvano Gonzales A. Marcia A. Rizzutto Enrico Poli Cristiane Calza marcelino dos Anjos Ricardo T. Lopes Giovanni E. Gigante Gabriel M. Ingo Cristina Riccucci Carlos Elera Izumi Shimada Victor Curay Castillo G and Fabio Lopes Dipartimento di Matematica e Fisica Universith di Sassari Sassari Italy Universidad Nacional Mayor de San Marcos Lima Peri4 Museo ＂Tumbas Reales de Sip6n ＂ Lambayeque Perlt Instituto de Fisica Universidade de S6o Paulo SP Brasil Asociaci6n cultural e Museo Enrico Poli Lima Peru COPPE Universidade Federal do Rio de Janeiro Rio de Janeiro Brasil Dipartimento di Energetica Universith di Roma ＂La Sapienza ＂ Rome Italy lstituto Studio dei Materiali Nanostrutturati-CNR Area Ricerca RM1-Montelibretti Rome Italy Museo de Sic6n Ferrahqfe Perit Istituto Nacional de Cultura Piura Peru Universidade Estadual de Londrina Londrina PR Brasil

On the north coast of present-day Peru, between the Andes and the Pacific Ocean, prospered approximately between 1000 BC and 1375 AD, several relevant cultures: Chavín (1000-200 BC), Vicús and Frías (200 BC - 300 AD), Moche (400 BC-700 AD), Sicán (700-1375 AD). These cultures are interconnected and characterized by a high metallurgical ability, demonstrated by the presence of beautiful artifacts on gold, silver and copper alloys. More than hundred metal artefacts from these cultures were analyzed with a portable equipment which uses the non-destructive and non-invasive technique of energy-dispersive X-ray fluorescence (EDXRF). Following objects were analyzed: (1) gold, silver and copper objects from the Chavín culture (Museo Municipal of Piura and and Museo Enrico Poli in Lima); (2) gold and silver objects from the Vicús and Frías cultures (Museo Municipal of Piura); (3) gold, silver and copper objects from the Moche culture ("Museo Tumbas Reales de Sipán", "Museo de Sitio de Huaca Rajada" in Lambayeque and Museo Enrico Poli in Lima); (4) gold, silver and copper objects from the Sicán culture (Museum of Sicán, Ferra?afe). Portable equipments were employed, mainly composed of a small size X-ray tube and a thermoelectrically cooled, small size, Si-PIN or Si-drift X-ray detectors. The main characteristics of the EDXRF-technique is of being non destructive and multi-elemental. Standard samples of gold and silver alloys were employed for calibration and quantitative analysis. The aims of this campaign of analysis were: (1) to analyze a large number of objects; (2) to differentiate gold, gilded copper and tumbaga (this last being a poor gold alloy enriched at the surface by depletion gilding); (3) to correlate, when possible, composition of analyzed alloys to the specific culture; (4) to determine a possible evolution of metallurgy; (5) to better determine characteristics and beginning time of tumbaga production. It was determined that the analyzed artefacts are composed

关键词： X射线荧光技术能量色散侵入性冶金鲁北设备使用便携式哥伦布

Fecal immunochemical test accuracy in average-risk colorectal cancer screening

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World Journal of Gastroenterology 2014年第4期20卷 1038-1047页

作者： Vicent Hernandez Joaquin Cubiella M carmen Gonzalez-Mao Felipe Iglesias Concepción Rivera M Begoa Iglesias Lucía Cid Ines Castro Luisa de Castro Pablo vega Jose Antonio Hermo Ramiro Macenlle Alfonso Martínez-Turnes David Martínez-Ares Pamela Estevez Estela Cid M carmen Vidal Angeles López-Martínez Elisabeth Hijona Marta Herreros-Villanueva Luis Bujanda Jose Ignacio Rodriguez-Prada the COLONPREV study investigators Department of Gastroenterology Complexo Hospitalario Universitario de Vigo Department of Gastroenterology Complexo Hospitalario Universitario de Ourense Department of Clinical Analysis Complexo Hospitalario Universitario de Vigo Department of Pathology Complexo Hospitalario Universitario de Vigo Department of Gastroenterology Donostia Hospital Biodonostia Institute University of the Basque Country UPV/EHU

AIM:To assess the fecal immunochemical test(FIT)accuracy for colorectal cancer(CRC)and advanced neoplasia(AN)detection in CRC ***:We performed a multicentric,prospective,double blind study of diagnostic tests on asymptomatic average-risk individuals submitted to screening *** stool samples were collected and the fecal hemoglobin concentration was determined in the first sample(FIT1)and the highest level of both samples(FITmax)using the *** under the curve(AUC)for CRC and AN were *** best FIT1and FITmax cut-off values for CRC were *** this threshold,number needed to scope(NNS)to detect a CRC and an AN and the cost per lesion detected were ***:About 779 individuals were *** AN was found in 97(12.5%)individuals:a CRC in 5(0.6%)and an advanced adenoma(≥10 mm,villous histology or high grade dysplasia)in 92(11.9%)*** CRC diagnosis,FIT1 AUC was 0.96(95%CI:0.95-0.98)and FITmax AUC was 0.95(95%CI:0.93-0.97).For AN,FIT1 and FITmax AUC were similar(0.72,95%CI:0.66-0.78 vs 0.73,95%CI:0.68-0.79,respectively,P=0.34).Depending on the number of determinations and the positivity threshold cut-off used sensitivity for AN detection ranged between 28%and 42%and specificity between 91%and 97%.At the best cut-off point for CRC detection(115 ng/mL),the NNS to detect a CRC were 10.2 and 15.8;and the cost per CRC was 1814€and 2985€on FIT1 and FITmax strategies *** this threshold the sensitivity,NNS and cost per AN detected were 30%,1.76,and 306€,in FIT1 strategy,and 36%,2.26€and 426€,in FITmax strategy,***:Performing two tests does not improve diagnostic accuracy,but increases cost and NNS to detect a lesion.

关键词： Colorectal neoplasms Early detection of cancer Sen

Sudden Death in Sports: Case Report and Review of an Ongoing Problem

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Health 2019年第1期11卷 67-80页

作者： María Elena Caparrós-Hernández Mónica García-Fernández Carla Miró-Vicedo María del Mar Ponce-Abellán Andrea Ruso-Ruso María Dolores Jover-Ríos Juan Méndez-Mora Francisco Caparrós-Hernández carmen Seguí-Pérez Marc Seguí-Pérez Pedro Esteve-Atiénzar Jorge Peris-García David Bonet-Tur Pablo Roig-Rico Asunción Pérez-Fullana José Miguel Seguí-Ripoll School of Medicine Miguel Hernández University Elche (Alicante) Spain Department of Internal Medicine Hospital La Vega Baja of Orihuela (Alicante) Spain Secondary School Marist Brothers High School Alicante Spain Department of Internal Medicine University Hospital of San Juan Alicante Spain Department of Clinical Medicine Miguel Hernández University Elche (Alicante) Spain

Background: Both competitive and recreational sports are considered a positive practice that is good for human health and quality of life, so it is difficult to understand how young, energetic and apparently healthy people can die while playing their usual sports. When these events occur in elite athletes during monitored events, they normally receive considerable media attention. Objective: To describe the case of sudden death in a young professional athlete who was successfully aided and resuscitated outside our hospital, and to review the literature about sudden death in sports. Materials and Method: We searched for Sudden Death (according to the International Classification of Diseases (ICD-9 and ICD-10)) in our hospital but found no other relevant cases. We performed a literature search on the state of the art in sudden death (Google Scholar, PubMed, LILACS, Scielo and the Revista Española de Cardiología). Results: Although we observed that the prevalence of sudden death is not very high, it still represents a potentially avoidable event. An adequate medical examination prior to regular sporting practice can decrease the incidence of sudden death in athletes under the age of 35. Data available in the literature support medical check-ups that include history-taking, physical examination and electrocardiogram. The findings of this evaluation may also prompt further assessment (electrocardiograph, ergometry). Conclusions: We could not identify standard, obligatory guidelines for screening possible heart diseases causing cardiorespiratory failure and sudden death. As a measure for primary prevention, we propose a protocol for reducing the risk of sudden death in athletes.

关键词： Sudden Death Sports Athletes Cardiopulmonary Resuscitation Implantable Automatic Defibrillator

Post-Hospital Syndrome and Hyponatremia

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Health 2021年第8期13卷 846-856页

作者： José Bellod-Tonda Julio Blázquez-Encinar María Dolores Jover-Ríos carmen Seguí-Pérez Juan Méndez-Mora Francisco Caparrós-Hernández Álex Méndez-Jover Marc Seguí-Pérez David Baláž Leticia Espinosa del Barrio Jesús Corbacho-Redondo Carles García-Cervera Juan Manuel Núñez-Cruz Isidro Hernández-Isasi Javier Guzmán-Martínez Angie Gómez-Uranga Pedro Esteve-Atiénzar Jorge Peris-García Veronica Martínez-Sempere Eliana Damonte-White Óscar Hernando Ruiz-Ariza Juan Carlos López-Corbalán Lourdes Lajara-Villar Andrea Riaño-Pérez Paloma Chazarra-Pérez María Escamilla-Espínola Maria Luisa Asensio-Tomás Miguel Ángel Auladell-Alemany Laura Serna-Torres Asunción Pérez-Fullana Amparo Gómez-Siurana Sergio Menargues-Irles José Miguel Seguí-Ripoll Internal Medicine Department University Hospital of San Juan Alicante Spain Internal Medicine Department Torrevieja University Hospital Alicante Spain Internal Medicine Department Hospital La Vega Baja of Orihuela Alicante Spain CEU Cardinal Herrera University Veterinary Hospital Valencia Spain Secondary School Marist Brothers High School Alicante Spain Department of Clinical Medicine Miguel Hernández University Elche Spain Primary Care Medicine Benilloba Spain Sub-delegation of the Government Alicante Spain Chemical Engineering Department University of Alicante Alicante Spain

Introduction: Post-hospital syndrome (PHS) is defined as a period of vulnerability during the first 30 days after a patient is discharged from hospital, in which multiple factors come into play. Hyponatremia is the most frequent hydroelectrolytic disorder in hospitalized patients and may be related to the appearance of PHS. Objective: The objective is to estimate the prevalence of PHS that is assessed as the rate of readmissions in the first 30 days after discharge, in patients with hyponatremia. Material and Methods: It is a descriptive observational study of patients with hyponatremia who were discharged from 1 September 2010 to 2 February 2020 at the Internal Medicine Service of the Hospital University of San Juan (Alicante, Spain). Results: Of the 25 included patients, 5 (20%) were readmitted within a month of discharge, after a mean of 11.4 days (standard deviation [SD] 5.1). The overall mortality of the study was 20% (n = 5), with one case of death in the first 30 days post-hospitalization (4%). In 12 patients (48%) the origin of the hyponatremia was undetermined. The most frequently recorded etiology for the condition was pharmacological (n = 7, 28%), and there was pronounced variability in its clinical and laboratory study. The most widely used corrective measure was drug withdrawal, in 16 patients (64%). Water intake restriction was the most common treatment after discharge (5 patients, 20%), followed by urea (2 patients, 8%), while tolvaptan was not used. Conclusion: Hyponatremia may be the cause of PHS, which could increase the rate of early readmission. Hyponatremia is an underdiagnosed and undertreated entity, so it is necessary to apply an appropriate system to optimize its management and, in future studies, to assess its impact on PHS.

关键词： Hospitalization Hyponatremia Patient Readmission Inappropriate ADH Syndrome