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Health 2020年第10期12卷 1360-1370页

作者： Lucas Lima de Carvalho Lucas Rodrigues Claro Amanda dos Santos Cabral marcela pereira da silva mello Bruna Liane Passos Lucas Marcelly Valadares Souza Simone Fonseca Lucas Alexandre Oliveira Tellles Ravini Fernandez dos Santos Vieira dos Santos Marcia Augusta pereira dos Santos Claudia Lima Campos Alzuguir Maria Cristina Dias da silva Antonio Eduardo Vieira dos Santos Maria Antonieta Rubio Tyrrell Eduardo Alexander Júlio César Fonseca Lucas Anna Nery School of Nursing Federal University of Rio de Janeiro Rio de Janeiro Brazil Celso Lisboa University Center Rio de Janeiro Brazil State Secretariat of Education of Rio de Janeiro Rio de Janeiro Brazil Department of Medicine in Primary Health Care Faculty of Medicine Federal University of Rio de Janeiro Rio de Janeiro Brazil Department of Maternal and Child Nursing Faculty of Nursing State University of Rio de Janeiro Rio de Janeiro Brazil Department of Maternal-Child Nursing Faculty of Nursing Fernandez Figueira Institute of the Oswaldo Cruz Foundation State University of Rio de Janeiro Rio de Janeiro Brazil

This documentary research aimed to describe the results of an epidemiological survey that sought to determine the prevalence of Infections Related to Health Care (IRHC) in newborns admitted to a Neonatal Intensive Care Unit (NICU) at the city of Rio de Janeiro. For methodology, the existing data in the original research database were used as the primary source. The method used was the case study in a quantitative approach. The data have been statistically arranged by odds ratio, which measured the possibility of IRHC development at the 102 newborns, by exposition at the risk factors. Results: IRHC prevalence with pneumonias, sepsis, navel’s infection and ocular infections predominance rises. Prematures are 4.10 more susceptible. Twelve hours after amniotic rupture there are 1.77 more chances of infections. Babies with more than 10 days of hospitalization are 4.70 more susceptible than those with 10 days. The registers examined were incipient at the IRHC’s characterization, beginning and duration, which make the IRHC’s diagnostic/notification difficult.

关键词： Neonatal Nursing Cross Infection data Interpretation Statistical

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Health（健康） 2020年第10期

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Protection status as determinant of carbon stock drivers in Cerrado sensu stricto

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Journal of Plant Ecology 2020年第3期13卷 361-368页

作者： Kelly Marianne Guimarães pereira Natielle Gomes Cordeiro marcela de Castro Nunes Santos Terra marcela Venelli Pyles Christian Dias Cabacinha JoséMárcio de mello Eduardo van den Berg Department of Biology Federal University of LavrasCampus UniversitárioCEP 37200-000LavrasMinas Gerais stateBrazil Department of Forest Sciences Federal University of LavrasCampus UniversitárioCEP 37200-000LavrasMinas Gerais stateBrazil Department of Forest Sciences Institute of Agrarian SciencesFederal University of Minas GeraisCampus Regional de Montes ClarosCEP 39.404-547Montes ClarosMinas Gerais stateBrazil

Aims Natural vegetation plays an important role in global carbon cycling and ***,the Cerrado(Brazilian savannah)is considered a carbon sink because of its intrinsic *** aim was to evaluate how the aboveground biomass and biodiversity relationship change between three Cerrado remnants with different protection status:a‘control area’(Legal Reserve area),a protected area(PA)and a non-protected area(Non-PA).Methods All three studied fragments are situated in northern Minas Gerais state,*** estimated the aboveground carbon stocks based on the forest *** also measured three dimensions of biodiversity metrics for each plot:functional trait dominance,taxonomic diversity and functional *** following functional traits were evaluated for the species:wood density,maximum diameter and seed *** carried out generalized linear models seeking to evaluate how carbon stocks,community-weighted mean(CWM)trait values,species richness and diversity,and functional diversity indices differ among the *** Findings The Cerrado areas without protection status had lower carbon stocks,species richness,species diversity,functional richness and functional dispersion,whereas both PA and Non-PA had lower CWM maximum diameter and seed size compared with the Legal Reserve control *** linear models showed that carbon stocks,species and functional richness metrics were correlated within and across sites,and thus,species richness could serve as a good proxy for functional richness and carbon *** carbon stocks were positively driven by species richness and CWM maximum diameter,while they were negatively driven by functional *** richness,species diversity and CWM seed size appeared in the set of best models,but with no significant direct effect on carbon ***,we concluded that absence of protection in the Cerrado areas decreases both species richness and carbon stocks.

关键词： functional traits biodiversity biomass storage Brazilian Savanna human impacts

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Methane production and small intestinal bacterial overgrowth in children living in a slum

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World Journal of Gastroenterology 2012年第41期18卷 5932-5939页

作者： Carolina Santos mello Soraia Tahan Lígia Cristina FL Melli Mirian silva do Carmo Rodrigues Ricardo Martin pereira de mello Isabel Cristina Affonso Scaletsky Mauro Batista de Morais Pediatric Gastroenterology Division Federal University of Sao Paulo04039-031 Sao PauloBrazil Center Foundation Institute of Education for Osasco 06020-190 Sao PauloBrazil Infectology Division Federal University of Sao Paulo04025-010 Sao PauloBrazil Microbiology Immunology and Parasitology DivisionFederal University of Sao Paulo 04023-062 Sao PauloBrazil

AIM:To analyze small intestinal bacterial overgrowth in school-aged children and the relationship between hydrogen and methane production in breath ***:This transversal study included 85 children residing in a slum and 43 children from a private school,all aged between 6 and 10 years,in Osasco,*** characterization of the groups,data regarding the socioeconomic status and basic housing sanitary conditions were *** data was obtained in children from both *** children completed the hydrogen(H 2) and methane(CH 4) breath test in order to assess small intestinal bacterial overgrowth(SIBO).SIBO was diagnosed when there was an increase in H 2 ≥ 20 ppm or CH 4 ≥ 10 ppm with regard to the fasting value until 60 min after lactulose ***:Children from the slum group had worse living conditions and lower nutritional indices than children from the private *** was found in 30.9%(26/84) of the children from the slum group and in 2.4%(1/41) from the private school group(P = 0.0007).Greater hydrogen production in the small intestine was observed in children from the slum group when compared to children from the private school(P = 0.007).A higher concentration of hydrogen in the small intestine(P < 0.001) and in the colon(P < 0.001) was observed among the children from the slum group with SIBO when compared to children from the slum group without *** production was observed in 63.1%(53/84) of the children from the slum group and in 19.5%(8/41) of the children from the private school group(P < 0.0001).Methane production was observed in 38/58(65.5%) of the children without SIBO and in 15/26(57.7%) of the children with SIBO from the *** production of hydrogen was lower in methaneproducing children(P = 0.017).CONCLUSION:Children who live in inadequate environmental conditions are at risk of bacterial overgrowth and methane *** is a substrate for methane production in the colon.

关键词： Bacterial overgrowth Breath test Children Colon Hydrogen Methane Small intestine

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Water availability drives gradients of tree diversity,structure and functional traits in the Atlantic-Cerrado-Caatinga transition,Brazil

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Journal of Plant Ecology 2018年第6期11卷 803-814页

作者： marcela de Castro Nunes Santos Terra Rubens Manoel dos Santos Jamir Afonso do Prado Júnior José Marcio de mello José Roberto Soares Scolforo Marco Aurélio Leite Fontes Ivan Schiavini Aliny Aparecida dos Reis Inacio Thomaz Bueno Luiz Fernando silva Magnago Hans ter Steege Departamento de Ciências Florestais Universidade Federal de LavrasCampus UniversitárioPO Box 3037LavrasMinas Gerais 37200-000Brazil Instituto de Biologia Universidade Federal de UberlândiaCampus Umuarama-Bloco 2DPO Box 593UberlândiaMinas Gerais 38400-902Brazil Applied Ecology and Conservation Lab Programa de Pós‐graduação Ecologia e Conservação da BiodiversidadeUniversidade Estadual de Santa CruzIlhéusBahia 45662-900Brazil Naturalis Biodiversity Center Vondellaan 55Postbus 95172300 RA LeidenThe Netherlands Coordenação de Botânica Museu Paraense Emílio GoeldiAv.Magalhães Barata 376PO Box 399BelémPara´66040-170Brazil

Aims Climate and soil are among the most important factors determin-ing variation in tree communities,but their effects have not been thoroughly elucidated to date for many vegetation *** this study,we evaluate how climate and soil gradients affect gradients of vegetation composition,species diversity and dominance,structure and functional traits(seed mass and wood density)using over 327000 trees in 158 sites distributed along environmental gradients in the transitions among the Atlantic forest,Cerrado and Caatinga in Minas Gerais State(MG),Brazil(nearly 600000 km2).Methods Gradients in species,genus and family abundance in addition to basal area,stem density,species diversity(Fisher’s alpha),domin-ance percentage,seed mass and wood density were correlated using multiple regressions with environmental variables,as summarized in four principal component analysis axes(two climatic-precipi-tation seasonality and temperature range-and two edaphic-soil fertility and soil moisture).Additionally,ordinary kriging maps were used to better illustrate the *** Findings Multiple regression models indicate that all variables but domin-ance percentage were affected by one or more of the environmental gradients,but the average R2 was low(26.25%).Kriging maps rein-forced the patterns observed in the regression *** seasonality and soil moisture gradients were the most important gra-dients affecting vegetation *** finding suggests that water availability is an important determinant of vegetation features in these vegetation transitions.

关键词： climate environmental gradient soil southeastern Brazil vegetation

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Educational Video Increases Maternal Self-Efficacy for Prevention of Diarrhoea in Young Children:A Randomised Clinical Trial

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Health 2014年第21期6卷 2867-2874页

作者： Emanuella silva Joventino Adria marcela Vieira Ferreira Maria de Fátima pereira de Sousa Jardeliny Correa da Penha Monica Oliveira Batista Oria Paulo Cesar de Almeida Lorena Barbosa Ximenes Department of Nursing Federal University of CearáFortalezaBrazil University of the State of Ceará FortalezaBrazil

The aim of this study was to compare the scores of maternal self-efficacy for child diarrhoea prevention, between intervention and control groups, according to sanitary, social and demographic characteristics. A randomised clinical trial was carried out on 163 mothers of children under 5 years old. data collection was conducted during two months, at two different moments (M0 and M1);at the moment M0 only the intervention group watched the educational video to promote self-efficacy for child diarrhoea prevention;at M1 (two months later) the scale was applied to both groups. In the intervention group, greater mean self-efficacy scores were obtained compared with the control group. The following variables showed statistically significant associations (p < 0.05) with maternal self-efficacy: age 35 or over;high school education;working outside the home;residence with 4 to 5 people;house not of brick or mortar;public refuse collection;piped water supply;consumption of mineral water;and public sewerage network. After use of the video “Diarrhoea: you can prevent it”, the maternal self-efficacy increased, proving that this strategy is able to assist the nursing staff in educational practices.

关键词： Health Education Diarrhoea Infantile Maternal Behaviour Randomised Controlled Trial

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Assessment of Educational Videos on the Prevention and Management of Infant Diarrhea:Documental Study

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Health 2015年第9期7卷 1215-1223页

作者： Elizamar Regina da Rocha Mendes Jardeliny Correa da Penha Ludmila Alves do Nascimento Leidiane Minervina Moraes de Sabino Emanuella silva Joventino Adria marcela Vieira Ferreira Olinda Costa Mota Teixeira Maria de Fátima pereira de Sousa Galvao Lorena Barbosa Ximenes Federal University of Ceará FortalezaBrazil Federal University of Piauí FlorianoBrazil University of International Integration of African-Brazilian Lusophony RedencaoBrazil

Objective: To evaluate the suitability of educational videos produced in Brazil that addressed aspects related to prevention and/or management of infant diarrhea according to content;language;graphic illustrations;stimulation for learning/motivation and cultural fit. Method: Documentary study, which evaluated six educational videos from an adapted and validated tool, the Suitability Assessment of Materials. Three nurses evaluated the videos. data were processed using the Statistical Package for the Social Sciences, version 17.0, and presented in tables and graphics. Results: It was found that 4 (66.6%) of the educational videos were classified as appropriate, ranging from 60% to 63.3% of full approval, and 2 (33.3%) were assessed as higher, reaching up to 83.3% to 90% approval. Considering the socioeconomic and cultural contexts of the videos to the audience, they assigned notes ranging from 6 to 9 in a rating ranging from 0, the minimum score, to 10, the highest score. Conclusion: The educational videos were considered adequate, with positive results about the content on the prevention and management of infant diarrhea, being appropriate for the target audience. As a result, greater credibility is ratified as the use thereof, since these resources can contribute to health promotion and prevention of diarrhea in children.

关键词： Diarrhea Infantile Educational Technology Child Health

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Use of Silicon in Mitigating Ammonium Toxicity in Maize Plants

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American Journal of Plant Sciences 2015年第11期6卷 1780-1784页

作者： Cid Naudi silva Campos Renato de mello Prado Cassiano Garcia Roque Antonio Joao de Lima Neto Luiz Junior pereira Marques Aridênia Peixoto Chaves Claudia Amaral Cruz Department of Soils and Fertilizers Universidade Estadual Paulista/FCAV Jaboticabal Brazil Department of Soils and Fertilizers Universidade Estadual Paulista/FCAV Jaboticabal Brazil Universidade Federal de Mato Grosso do Sul Chapad&atildeo do Sul Brazil Universidade Federal de Viçosa Vi&ccedilosa Brazil Department of Applied Biology and Agriculture Universidade Estadual Paulista/FCAV Jaboticabal Brazil Department of Plant Science Universidade Federal Rural do Semi-árido Mossoró Brazil M.Sc. in Agronomy Natal Brazil

Silicon is a beneficial element that can mitigate abiotic stresses, such as ammonium toxicity. The objective herein was to evaluate the effects of silicon (Si) on mitigating toxicity caused by excess ammonium in maize plants grown in nutrient solution. An experiment was conducted with maize plants (cultivar DKB 390 VT Pro II) grown in a greenhouse in pots (8 L) in a hydroponic system. The treatments were arranged in a 2 × 2 factorial, consisting of two ammonium concentrations (30 and 60 mmol·L-1) in the absence and presence of Si (10 mmol·L-1), arranged in a completely randomized design with six repetitions. At 28 days after applying the treatments the dry mass of shoots and roots was evaluated, along with accumulation of silicon and nitrogen in the shoots. The use of silicon resulted in increases in the studied variables, regardless of ammonium concentrations. Silicon reduced the effect of toxicity caused by ammonium excess in maize plants, resulting in greater growth and dry matter accumulation.

关键词： Zea mays L. Beneficial Element Nitrogen Nutritional Disorder Abiotic Stress

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Ursolic Acid Derivatives Induced Apoptosis and Reduces the NF-κB in Human Lung Adenocarcinoma Cells

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Journal of Cancer Therapy 2019年第10期10卷 863-876页

作者： Elaine Carlos Scherrer Ydia Mariele Valadares Caio Cesar Souza Alves Gabriella Freitas Ferreira marcela pereira Leao Jessica Aline Soares Fernando Sa silva Alessandra Paula Carli Oswaldo Cardoso Jr. Fabiana Simao Machado Sandra Bertelli Ribeiro Castro Life Sciences Institute Federal University of Juiz de ForaGovernador ValadaresMGBrazil Faculty of Medicine Federal University of the Valleys of Jequitinhonha and MucuriTeofilo OtoniMGBrazil Department of Biochemistry and Immunology Federal University of Minas GeraisBelo HorizonteMGBrazil

Lung cancer is the major cause of death in the neoplastic diseases. In spite of the advances in the chemotherapy, the lung cancer treatments are still complex and costly, being necessary the seeking of new drugs. In this context, the ursolic acid (UA) becomes the target of studies that investigate its antitumor potential and, thus, structural modifications can enhance its biological activities. Eight UA semisynthetic derivative compounds (UAD1-8) were synthesized and evaluated their cytotoxic activity against human alveolar adenocarcinoma cells (A549). UAD1, UAD3, UAD5, UAD6 and UAD8 were able to reduce the viability of the A549 cells. Only UAD1 and UAD6 reduced the viability at 24 h, and only UAD3 didn’t reduce the NF-κB expression. The compound UAD1 showed the greater apoptosis induction. Moreover, the compound UAD1 showed better results than UA in all assays. The present study shows, for the first time, the action of these compounds in the apoptotic effect, in the expression of NF-κB and in the A549 cell line. The ursolic acid derivatives showed substantial results in the apoptosis, cytotoxicity and NF-κB inhibition of A549 cells, and further studies are necessary for the development of possible new therapeutic drugs.

关键词： Ursolic Acid Apoptosis NF-κB A549 Cells Tumoral

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A Structure and Antioxidant Activity Study of Paracetamol and Salicylic Acid

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Pharmacology & Pharmacy 2014年第13期5卷 1185-1191页

作者： Rosivaldo SBorges Taina G.Barros Glaecia A.N.pereira Joao Batista Jr Raimundo F.G.P.Beleza Filho Andrex A.S.Veiga Moises Hamoy Vanessa J.mello Alberico B.Fda silva Carlos A.L.Barros Nucleo de Estudos e Selecao de Moleculas Bioativas Instituto de Ciencias da SaudeUniversidade Federal do ParaBelemBrazil Laboratorio de Farmacologia e Toxicologia de Produtos Naturais Instituto de Ciencias da SaudeUniversidade Federal do ParaBelemBrazil Instituto de Quimica de Sao Carlos Universidade de Sao PauloSao CarlosBrazil

The paracetamol has more antioxidant properties than the salicylic acid on the several oxidative stress-forced models and one possible mechanism is due to electron or hydrogen transfer by the evaluated hydroxyl radicals. The antioxidant mechanism for the compounds studied here was performed by molecular modeling using quantum chemical calculations at the B3LYP level of theory. Our results show that the paracetamol has more antioxidant properties than the salicylic acid in experimental and theoretical studies. The theoretical mechanism show that the hydrogen transfer is more favorable than the electron transfer. From the study it was concluded that the electron abstraction for paracetamol is more favored than salicylic acid.

关键词： Paracetamol Salicylic Acid Phenol Derivatives NSAIDs Antioxidant

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