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Multilevel Cervicothoracic and Lumbar Pott’s Disease: About Three new and Unusual Cases in the Rheumatology Department of the Teaching Hospital of Cocody in Abidjan (Côte d’Ivoire)

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Open Journal of Rheumatology and Autoimmune Diseases 2015年第2期5卷 23-27页

作者： Mohamed Diomandé Ehaulier Soh Christian Louis kouakou Tamo Estelle Mégné Mariam Gbané-Koné Abidou Kawele Coulibaly Edmond Eti marcel n’zué kouakou Department of Rheumatology of University Hospital Center of Cocody Abidjan C&#244te d’Ivoire Department of Rheumatology of University Hospital Center of Bouaké Bouaké C&#244te d’Ivoire

Pott’s disease usually affects two contiguous vertebrae or two spinal levels. The involvement of the three cervicothoracic and lumbar levels is rarely described. Only three cases have been described in the literature to our knowledge. The authors report three new cases of tuberculous spondylodiscitis of cervicothoracic and lumbar site. Our three cases were characterized by symptoms similar to the other topographical forms of Pott’s disease. A predisposing factor is often identified like the infection with human immunodeficiency virus. The definitive diagnosis was made in two cases by identifying acid and alcohol-fast bacilli for one case and by histology for the other case. For the third case, there was a diagnostic presumption reinforced by the satisfactory outcome on tuberculosis chemotherapy for a period of 12 months. The multilevel nature of diseases does not influence the effectiveness of treatment of this form of spinal tuberculosis.

关键词： Pott’s Disease Spondylodiscitis Bone and Joint Tuberculosis Abidjan

Systemic Form of Juvenile Idiopathic Arthritis: Epidemiological, Clinical, Paraclinical and Therapeutic Aspects of 13 Cases in Abidjan

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Open Journal of Rheumatology and Autoimmune Diseases 2017年第2期7卷 103-110页

作者： Mohamed Diomandé Abidou Kawélé Coulibaly Astrid nawé ngandeu Cyprien kouakou Ehaulier Soh Christian Louis kouakou Kouassi Jean Mermoz Djaha Mariam Gbané-Koné Baly Ouattara Edmond Eti Jean Claude Daboiko marcel n’zué kouakou Department of Rheumatology University Hospital Center of Cocody Abidjan C&#244te d’Ivoire Department of Pediatrics University Hospital Center of Cocody Abidjan C&#244te d’Ivoire Department of Rheumatology University Hospital Center of Bouaké Bouaké C&#244te d’Ivoire

Objective: To describe the epidemiological, clinical, paraclinical and therapeutic aspects of systemic juvenile idiopathic arthritis observed in Abidjan. Materials and Method: This retrospective and descriptive study covered 13 children suffering from systemic juvenile idiopathic arthritis selected in the Rheumatology Department of University Hospital Center of Cocody in Abidjan (Cote d’Ivoire) from January 2005 to December 2015. We were interested to the sociodemographical, clinical, paraclinical and therapeutic aspects. Results: The systemic form of the juvenile idiopathic arthritis represented 0.2% of the 4608 rheumatologic diseases and 70.58% of the JIA. We selected 6 boys and 7 girls, with an average age of 10.8 years and mostly going to school (84.61%). The diagnostic delay was 18 months. The main clinical signs were fever and joint damage observed each in 100% of cases, impaired general condition (92.30%) and tumor syndrome (83.33%). Biological signs were characterized by hyperleukocytosis (69.20%) and the presence of a biologic inflammatory syndrome (on average, erythrocyte sedimentation rate 59.6 mm and C Reactive Protein 56.4 mg/l). The cervical damage was the essential functional complication (38.46%). The major treatment has been a therapeutic combination based on corticotherapy and methotrexate (100%) with 1 death case by macrophage activation syndrome. Conclusion: Systemic juvenile idiopathic arthritis is rarely diagnosed in the rheumatologic practice in Abidjan. It concerns children relatively big, and is characterized by a febrile polyarthritis with impaired general condition and tumor syndrome. This systemic form is treated by corticotherapy and methotrexate.

关键词： Systemic Idiopathic Juvenile Arthritis Juvenile Idiopathic Arthritis Profile Children Abidjan

Severe Axonal Peripheral Polyneuropathy Revealing a Systemic Lupus Erythematosus: About One Case

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Open Journal of Rheumatology and Autoimmune Diseases 2015年第2期5卷 36-39页

作者： Mariam Gbané-Koné Mohamed Diomandé Boubacar Ouali Abidou Kawalé Coulibaly Astrid nawé ngandeu Edmond Eti marcel n’zué kouakou Department of Rheumatology University Hospital Center of Cocody Abidjan C&ocircte d’Ivoire

Aim: We report a case of acute and severe sensorimotor peripheral polyneuropathy (with a severe motor damage) revealing a lupus. Case Presentation: A 48-year-old female patient was interned in rheumatology for a chronic polyarthritis. Four days after her hospitalisation, she was presenting a flask distal and proximal tetraparesia, with rapidly progressive installation. Electromyogram showed severe acute axonal sensorimotor polyneuropathy. The antinuclear antibody was positive as the anti-ds-DnA antibodies. The evolution has been unsatisfactory despite the high-dose corticotherapy and the immunosuppressor. Conclusion: Even if it is rare, peripheral neuropathy can be a lupus discovery circumstance.

关键词： Systemic Lupus Erythematosus EMG neurolupus Peripheral Polyneuropathy

Paraclinical, Therapeutic and Evolutionary Profile of Osteoarticular Tuberculosis: A Report about 550 Cases in Abidjan

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Open Journal of Rheumatology and Autoimmune Diseases 2015年第4期5卷 131-136页

作者： Mohamed Diomandé Fulgence Kaboré Ehaulier Soh Christian Louis kouakou Mariam Gbané-Koné Abidou Kawélé Coulibaly Kouassi Jean Mermoz Djaha Baly Ouattara Edmond Eti Jean Claude Daboiko marcel n’zué kouakou Department of Rheumatology University Hospital Center of Cocody Abidjan C&ocircte d’Ivoire Department of Rheumatology University Hospital Center of Bouaké Bouaké C&ocircte d’Ivoire

Objective: To describe paraclinical, therapeutic and evolutionary aspects of osteoarticular tuberculosis in Abidjan. Materials and Method: We realized a descriptive retrospective study carried out in the Rheumatology Department of the University Hospital Center of Cocody in Abidjan about 550 patients over a period of 10 years from January 2004 to December 2013. The paraclinical, therapeutic and evolutionary data had interested us. Results: Osteoarticular tuberculosis represented 12.13% of 4531 rheumatic diseases identified during the study period. The tuberculin skin test was positive in 78.49% of cases. An inflammatory syndrome was present with erythrocyte sedimentation rate and C-reactive protein respectively into 69.45% and 76.54% of cases. The research of Mycobacterium tuberculosis was realized into 176 of cases which 50% was positive. Polymerase chain reaction and biopsy of tissue were performed respectively in 8 and 6 cases. Plain radiography (89.82%) and computed tomography (83.63%) were the most realized imaging. Computed tomography has contributed for the diagnostic in 99.78% of cases. The majority of our patients (82.91%) received anti-tuberculous treatment which consisted of two months of combination of rifampicin (R), isoniazid (H), pyrazinamide (Z) and Ethambutol (E) (2RHZE), followed by 10 months of rifampicin (R) and isoniazid (H) (10 RH). The outcome in patients on this treatment was favorable in 528 cases (96%). Conclusion: This study revealed that the research of Mycobacterium tuberculosis was often realized and positive. On the contrary, polymerase chain reaction and biopsy of tissue were rarely performed. The main imaging is computed tomography. Our protocol of treatment is effective.

关键词： Osteoarticular Tuberculosis Biology Imaging Abidjan

Autoantibodies in Systemic Lupus Erythematosus, on Black African Subject, in Abidjan

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Open Journal of Rheumatology and Autoimmune Diseases 2015年第2期5卷 28-35页

作者： Mariam Gbané-Koné Baly Ouattara Kouassi Jean Mermoz Djaha Estelle Megne Astrid nawé ngandeu Abidou Kawalé Coulibaly Edmond Eti marcel n’zué kouakou Department of Rheumatology University Hospital Center of Cocody Abidjan C&#212te d’Ivoire

Aim: To determine the clinical and immunological characteristics of patients with systemic erythematosus lupus in Abidjan. Patients and Method: We studied 117 patients’ files with systemic lupus erythematosus aged 12 to 73 years old, who fulfilled the American College of Rheumatology (ACR)’s criteria. Antinuclear autoantibodies (AnA) were searched by indirect immunofluorescence. Anti-DnA native autoantibodies, extractable nuclear anti-antigens autoantibodies (anti-Sm, anti-SSA, anti-SSB and anti-RnP) and anti-phospholipids autoantibodies have been searched by ELISA technic. Results: The most frequent clinical manifestations were: articular damages (86.32%), cutaneous and mucosal lesions (71.79%) and fever (76.67%). Kidney damages have been noticed in 40.17%. neurologic manifestations have been observed in 36.75%. Pericarditis and pleurisies have been noticed in 22.22% and 11.97% of cases, and anaemia in 86.32% of cases. AnA have been detected in 94.12% of cases, anti-DnA native’s autoantibodies in 73.53% and anti-Sm autoantibodies in 75% of cases. Anti-SSA and anti-SSB autoantibodies were respectively in 75% and 56.25% of cases. Anti-RnP autoantibodies were in all the patients, and anti-phospholipids autoantibodies were in 37.50% of cases. Conclusion: Systemic lupus erythematosus of Ivorian black subject is characterised by high prevalence of autoantibodies, mostly Anti-RnP.

关键词： Sub-Saharan Africa Systemic Lupus Erythematosus Extractable nuclear Anti-Antigens Autoantibodies Anti-Phospholipids Autoantibodies ELISA

Assessment of Selenium Contamination in Sediments of the Aby and Tendo Lagoons in Côte d’Ivoire

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International Journal of Geosciences 2024年第4期15卷 334-349页

作者： Stéphane Jean Claon kouakou Serge Kouassi Kossonou Roland n’Guettia M’bassidjé Arsène Seka Guei Jokebed Dakouo Allico Joseph Djaman kouakou Luc Kouadio Analytical Sciences and Public Health Department University of F&#233lix Houphou&#235t-Boigny Abidjan C&#244te d&#8217Ivoire Water Quality Control and Analysis Laboratory (LACQUE) Office National de l&#8217Eau Potable (ONEP) Abidjan C&#244te d&#8217Ivoire Biology and Health Laboratory University of F&#233lix Houphou&#235t-Boigny Abidjan C&#244te d&#8217Ivoire Laboratory of Environmental Sciences (LSE) University of Nangui Abrogoua Abidjan C&#244te d&#8217Ivoire Department of Medical and Fundamental Biochemistry Institut Pasteur of C&#244te d&#8217Ivoire Abidjan C&#244te d&#8217Ivoire

Selenium is a trace element that can have both beneficial and harmful effects on aquatic life. The Aby Lagoon is a coastal environment in Côte d’Ivoire that receives selenium inputs from various natural and anthropogenic sources. The aim of this study was to assess the levels of selenium in the sediments of the Aby Lagoon and its tributaries, the Tanoe River and the Tendo Lagoon, and to examine the spatial and seasonal variations of selenium concentrations. Sediment samples were collected from different sites and seasons, and selenium concentrations were measured by atomic fluorescence spectrometry. The results showed that the average concentration of selenium in the sediments of the Aby Lagoon was 0.82 mg/kg, indicating moderate contamination. The concentration of selenium varied between sites and seasons, with higher values in the channel of the Tendo Lagoon and during the dry season. The study highlighted the complexity of selenium dynamics in aquatic ecosystems, and the need to take into account seasonal and spatial variability as well as interactions between environmental factors. The study also suggested potential ecotoxicological risks for some sensitive organisms in certain areas of the lagoon. This study contributes to the knowledge of the dynamics of selenium in lagoon ecosystems and to the assessment of the environmental risks associated with its presence.

关键词： Tropical Estuarine Selenium Sediments Aby Lagoon Seasonal Distribution

Detection of Burned Areas through Spectral Indices Analysis of Sentinel-2A Satellite Images in the Abokouamékro Wildlife Reserve (Central, Côte D’Ivoire)

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Open Journal of Applied Sciences 2024年第1期14卷 205-222页

作者： Bob kouakou Kouadio Sié Ouattara Alain Clément Jean-Marc Gala Bi Zaouri Jean-Luc Kouadio Kouassi Jean-Luc Edouard kouakou n’guessan Laboratoire des Sciences et Technologies de la Communication et de l’Information (LSTCI) Institut National Polytechnique Houphou&#235t Boigny (INP-HB) Yamoussoukro C&#244te d’Ivoire Laboratoire des Sciences Agronomiques et Génie Rural Institut National Polytechnique Houphou&#235t Boigny (INPHB) Yamoussoukro C&#244te d’Ivoire Ecole de Géomatique et du Territoire (EGT) Abidjan C&#244te d’Ivoire LARIS SFR MATHSTIC Université d’Angers Angers France Centre Universitaire de Recherche et d’application en Télédétection (CURAT) UFR des Sciences de la Terre et des Ressources Minières Abidjan C&#244te d’Ivoire Laboratoire de Botanique UFR Biosciences Université Félix Houphou&#235t Boigny Abidjan C&#244te d’Ivoire

In Côte d’Ivoire, the recurring and unregulated use of bushfires, which cause ecological damage, presents a pressing concern for the custodians of protected areas. This study aims to enhance our comprehension of the dynamics of burnt areas within the Abokouamékro Wildlife Reserve (AWR) by employing the analysis of spectral indices derived from satellite imagery. The research methodology began with the calculation of mean indices and their corresponding spectral sub-indices, including nDVI, SAVI, nDWI, nDMI, BAI, nBR, TCW, TCG, and TCB, utilizing data from the Sentinel-2A satellite image dated January 17, 2022. Subsequently, a fuzzy classification model was applied to these various indices and sub-indices, guided by the degree of membership α, with the goal of effectively distinguishing between burned and unburned areas. Following the classification, the accuracies of the classified indices and sub-indices were validated using the coordinates of 100 data points collected within the AWR through GPS technology. The results revealed that the overall accuracy of all indices and sub-indices declines as the degree of membership α decreases from 1 to 0. Among the mean spectral indices, nDVI-mean, SAVI-mean, nDMI-mean exhibited the highest overall accuracies, achieving 97%, 95%, and 90%, respectively. These results closely mirrored those obtained by sub-indices using band 8 (nDVI-B8, SAVI-B8, and nDMI-B8), which yield respective overall accuracies of 93%, 92%, and 89%. At a degree of membership α = 1, the estimated burned areas for the most effective indices encompassed 2144.38 hectares for nDVI-mean, 1932.14 hectares for mean SAVI-mean, and 4947.13 hectares for mean nDMI-mean. A prospective approach involving the amalgamation of these three indices could have the potential to yield improved outcomes. This study could be a substantial contribution to the discrimination of bushfires in Côte d’Ivoire.

关键词： Spectral Indices Wildfire Burned Areas Abokouamékro Wildlife Reserve Côte D’Ivoire

Growth of the Earthworm Millsonia omodeoi and Its Capacity to Accumulate Five Heavy Metals (HM) in Soils along a Toll Highway in Côte d’Ivoire

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Open Journal of Soil Science 2024年第1期14卷 115-132页

作者： Mamadou Toure Kpan kouakou Gains Kpan n’guetta Moïse Ehouman Seydou Tiho Laboratory of Ecology and Sustainable Development (LEDD) Department of Natural Sciences (UFR SN) University Nangui ABROGOUA Abidjan C&#244te d’Ivoire

The roads in correlation with the traffic linked to their existences are at the origin of the emission of numerous polluting substances likely to induce disturbances of the growth and the behavioral changes in the organisms living in their vicinities. The purpose of this study is to analyze the growth and capacity accumulation of a common earthworm species (Millsonia omodeoi) in Cu, Cr, ni, Pb and Zn in soils along a main road called “Autoroute du nord” in C?te d’Ivoire. Thus, the earthworms were harvested in soils from a distance of 0 m (just after the sidewalk) to a distance of 200 m from the toll highway and in a control soil sampled in Lamto reserve (C?te d’Ivoire). The study was carried out in the soil laboratory at the ecological station of Lamto reserve. The Ford-Walford technique was used to determine the model and parameters most appropriated for describing the growth of earthworms. A pairwise comparison of the growth parameters was carried out using the Kruskal-Wallis test with the STATISTICA 7.1 software. The heavy metals contained in the cultivated soils and earthworms were detected and quantified using a Scanning Electron Micro-scope (MEB FEG Supra 40 VP Zeiss) and an Atomic Absorption Spectrometer SPECTRA 110 (VARIAn). The capacity accumulation of heavy metals in earthworm was determined by the bioaccumulation factor (BAF) calculation. The results of this study showed that Gompertz is the most appropriated model to describe the growth of M. omodeoi. The life cycle of M. omodeoi shows that this earthworm adopts a K type demographic strategy. Cu is the most accumulated heavy metals in M. omodeoi, when Cr is the least accumulated. Concerning heavy metal content in the earthworms, it decreases while moving away from the pavement. These results highlight a possibility of choice of M. omodeoi as 1) indicators of heavy metals pollution and 2) target of biological organisms for environmental impact studies.

关键词： M. omodeoi Bioaccumulation Heavy Metals “Autoroute du nord” Côte d’Ivoire

Assessment of nitrates and nitrites in Borehole Water from the Southern and the northern Region of Côte d’Ivoire (West Africa)

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Open Journal of Modern Hydrology 2024年第2期14卷 87-105页

作者： Jean Stéphane Claon Kouassi kouakou Serge Sérikipré Laurent Seka M’Bassidjé Arsène n’Guettia Kossonou Roland Traoré Aïcha Djamanallico Joseph Kouadio kouakou Luc Analytical Sciences and Public Health Department University of Félix Houphou&#235t-Boigny Abidjan C&#244te d’Ivoire Water Quality Control and Analysis Laboratory (LACQUE) Office National de l’Eau Potable (ONEP) Abidjan C&#244te d’Ivoire Biology and Health Laboratory University of Félix Houphou&#235t-Boigny Abidjan C&#244te d’Ivoire Department of Medical and Fundamental Biochemistry Institut Pasteur of C&#244te d’Ivoire Abidjan C&#244te d’Ivoire Laboratory of Environmental Sciences (LSE) University of Nangui Abrogoua Abidjan C&#244te d’Ivoire

This study aimed to evaluate the quality of water from village boreholes by measuring physicochemical parameters such as nitrates, nitrites, and total organic carbon (TOC). Forty-five (45) village pumps from the Southern (Basse Côte) and the northern (Korhogo) region of Cte d’Ivoire (west Africa) were sampled. Physicochemical parameters such as temperature, pH, conductivity at 25˚C, and turbidity were determined in situ, while nitrite and nitrate were analyzed according to ISO 10304-1 (2007) standard and total organic carbon (TOC) by nF En 1484 (1997) standard. The results showed that the borehole waters of the Basse Côte and Korhogo analyzed are acidic, with an average temperature of 27.51˚C ± 0.16˚C and 29.95˚C ± 0.51˚C respectively for the Basse Côte and Korhogo regions. The borehole waters of the Basse Côtedo not contain nitrites, while those of Korhogo have average nitrite contents of 0.32 mg/l. The average nitrate rate in the waters of the Basse Côte and Korhogo are 12.08 ± 2.11 mg/l and 11.03 ± 3.18 mg/l respectively. The average TOC concentration of the waters of the Basse Côte is 1.28 ± 0.32 mg/l and that of Korhogo is 0.56 ± 0.09 mg/L. The study showed that the borehole waters of the Basse Côte and Korhogo have average temperatures between 27.4˚C and 29.95˚C with a slightly acidic pH value and acceptable salinity. The TOC concentrations obtained at the different sampling points were all below the French standard (2 mg/L) except for certains pumps of the Basse Côte. The water samples from the Basse Côte were devoid of nitrite. On the other hand, those from Korhogo revealed the presence of nitrite. Also, the borehole waters of the regions of the Basse Côte and Korhogo contain relatively high nitrate contents, presumably due to anthropometric activity. Overall, our study on the quality of drinking water showed that the waters analyzed are in compliance with international standards and safe for consumption.

关键词： Drinking Water pH Turbidity TOC nitrates nitrites Health Effect