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Incidence and mortality of acute and chronic pancreatitis in the Netherlands:A nationwide record-linked cohort study for the years 1995-2005

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World Journal of gastroenterology 2013年第20期19卷 3018-3026页

作者： BW marcel Spanier Marco J Bruno marcel gW dijkgraaf Department of gastroenterology and Hepatology Rijnstate Hospital6800 TA ArnhemThe Netherlands Department of gastroenterology and Hepatology Erasmus Medical Center3015 CE RotterdamThe Netherlands Clinical Research Unit Academic Medical Center1105 AZ AmsterdamThe Netherlands

AIM:To analyze trends in incidence and mortality of acute pancreatitis(AP) and chronic pancreatitis(CP) in the Netherlands and for international standard ***:A nationwide cohort is identified through record linkage of hospital data for AP and CP,accumulated from three nationwide Dutch registries:the hospital discharge register,the population register,and the death certificate ***-and age-group specific incidence rates of AP and CP are defined for the period 2000-2005 and mortality rates of AP and CP for the period ***,incidence and mortality rates over time are reported for Dutch and international(European and World Health Organization) standard ***:Incidence of AP per 100000 persons per year increased between 2000 and 2005 from 13.2(95%CI:12.6-13.8) to 14.7(95%CI:14.1-15.3).Incidence of AP for males increased from 13.8(95%CI:12.9-14.7) to 15.2(95%CI:14.3-16.1),for females from 12.7(95%CI:11.9-13.5) to 14.2(95%CI:13.4-15.1).Irregular patterns over time emerged for *** mean incidence per 100000 persons per year was 1.77,for males 2.16,and for females *** for AP fluctuated during 1995-2005 between 6.9 and 11.7 per million persons per year and was almost similar for males and *** CP,mortality for males fluctuated between 1.1(95%CI:0.6-2.3) and 4.0(95%CI:2.8-5.8),for females between 0.7(95%CI:0.3-1.6) and 2.0(95%CI:1.2-3.2).Incidence and mortality of AP and CP increased markedly with *** rates were lowest for World Health Organization standard ***:Incidence of AP steadily increased while incidence of CP *** for both AP and CP remained fairly *** burden and health care costs probably will increase because of an ageing Dutch population.

关键词： Acute pancreatitis Chronic pancreatitis Epidemiology Incidence Mortality

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较大直肠腺瘤中经肛门内镜显微手术与内镜下黏膜切除术的随机对照试验(TREND研究)

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英国医学杂志中文版 2018年第11期21卷 676-676页

作者： Renee M Barendse gijsbert D Musters Eelco J R de graaf Frank J C van den Broek Esther C J Consten Pascal g Doornebosch James C Hardwick Ignace H J T de Hingh Chrisiaan Hoft Jeroen M Jansen A W Marc van Milligen de Wit george P van der Schelling Erik J Schoon Matthijs P Schwartz Bas L A M Weusten marcel g dijkgraaf Paul Fockens Willem A Bemelman Evelien Dekker TREND研究小组李佳宁(译) 吴东(校) 不详北京协和医院消化科

摘要目的非随机研究表明内镜下黏膜切除术(endoscopic mucosal resection,EMR)在切除直肠较大腺瘤时与经肛门内镜显微手术(transanal endoscopic microsurgery,TEM)同样有效,但EMR可能更具成本效益且相对安全。本试验旨在对比摘除较... 详细信息

摘要目的非随机研究表明内镜下黏膜切除术(endoscopic mucosal resection,EMR)在切除直肠较大腺瘤时与经肛门内镜显微手术(transanal endoscopic microsurgery,TEM)同样有效,但EMR可能更具成本效益且相对安全。本试验旨在对比摘除较大直肠腺瘤时EMR与TEM的临床结局与成本效益。

关键词：随机对照试验显微手术切除术内镜黏膜肛门肠腺成本效益

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大便失禁的门诊患者的相关消费

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世界核心医学期刊文摘（胃肠病学分册） 2005年第10期1卷 53-54页

作者： Deutekom M. Dobben A.C. dijkgraaf M.g.W. 郝筱倩 Department of Clinical Epidemiology and Biostatistics Meibergdreef 91105 AZ Amsterdam Netherlands

Objective. Fecal incontinence is a problem with a high prevalence. Patients generally suffer from their problems for many years. It has been shown that quality of life is negatively affected but health economic data for fecal incontinence are limited. The aim of this study was to estimate the costs associated with fecal incontinence in a large outpatient study group, taking a societal perspective. Material and methods. Based on questionnaire data, we calculated the costs of health-care resources, out-of pocket expenses and costs associated with production losses in paid and unpaid work. Results. Data were available for 253 patients, of which 228 (90%) were female and 209 (83%) were treated in an academic medical center. The mean age of patients was 59 years (SD ±13) with a mean duration of incontinence of 8.5 years (SD ±8.3). Total costs were estimated on 2169 per fecal incontinent patient per year. Production losses in paid and unpaid work accounted for more than half of the total costs and costs of health-care visits accounted for almost a fifth of total costs. Costs associated with protective material (partially reimbursable and not reimbursable) formed only one-tenth of total costs, while incontinence medication was responsible for only 5%of total costs. Conclusions. More than half of total costs of fecal incontinence are made up of indirect non-medical costs. The costs associated with the use of incontinence material and other personal expenses are limited.

关键词：大便失禁问卷数据卫生保健患病时间医疗性体格检查生活质量一所

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