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Sperm function, mitochondrial activity and in vivo fertility are associated to their mitochondrial DNA content in pigs.

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Ecogenotoxicology in earthworms： A review

畜牧与生物技术杂志(英文版) 2024年第4期 1550页

作者： marc Llavanera Yentel Mateo-Otero Estel Vi?olas-Vergés Sergi Bonet marc Yeste

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Current Zoology 2014年第2期60卷 255-272页

作者： Paule VASSEUR marc BONNARD CNRS UMR 7360 Laboratoire Interdiscipinaire des Environnements Continentaux (LIEC) Universit6 de Lorraine MetzFrance Unité Interactions Animal-Environnement (IAE) - EA 4689 Universit6 de Reims Champagne-Ardenne (URCA) Reims France

Pollutant dynamics and bioavailability greatly differ in soil and aquatic systems. Therefore, specific approaches and models are needed to assess the impact of soil contamination to terrestrial ecosystems. Earthworms among other soil invertebrates have received more attention because of their ecological importance. They represent a dominant part of the soil biomass and are soil engineers regulating important soil processes, notably fertilization. The release in soils of pollutants known for their persistence and/or their toxicity is a concern. Exposure of terrestrial species to pollutants that may alter genomic function has become an increasing topic of research in the last decade. Indeed, genome disturbances due to genetic and epigenetic mechanisms may impair growth, as well as reproduction and population dynamics in the long term. Despite their importance in gene expres- sion, epigenetic mechanisms are not yet understood in soil invertebrates. Until now, pollutant-induced changes in genome expression in natural biota are still being studied through structural alteration of DNA. The first biomarker relating to genotoxicant exposure in earthworms from multi-contaminated soils reported is DNA adducts measurements. It has been replaced by DNA breakage measured by the Comet assay, now more commonly used. Functional genomic changes are now being explored owing to molecular ＂omic＂ technologies. Approaches, objectives and results are overviewed herein. The focus is on studies dealing with genotoxicity and populational effects established from environmentally-relevant experiments and in situ studies [Current Zoology 60 （2）： 255-272, 2014].

关键词： DNA adducts Comet assay Transcriptomic DNA methylation Pollutants Tolerance

Practical numerical simulation of the effect of TBM process pressures on soil displacements through 3D shift iteration

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Underground Space 2018年第4期3卷 297-309页

作者： Benno Ring marc Comulada Ring–Consultancy in Tunnelling Alpenstr.582131 StockdorfGermany Maidl Tunnelconsultants Goethestr.7480336 MunichGermany

A 3D-finite element model is illustrated that allows for the iterative simulation of the shield drive with its face and grouting pressures by shifting the determined stresses and displacements after each calculation *** are performed for the tunneling of Rio de Janeiro’s Line 4 and compared to the results of analytical limit equilibrium analyses and monitoring results of the actual TBM-drive.

关键词： Settlements TBM pressures 3D-Finite element method Numerical simulation Shift iteration

Post-Traumatic Palatine Odontogenic Abscess: About 2 Cases

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Open Journal of Stomatology 2024年第7期14卷 336-340页

作者： Aké Lucien Jonathan Yapo Bakary Ouattara Koffi Laurent Boka Konan René Kouakou Ahi Morel Mounin Chapo Affoué Linda Marie Pierre Koffi Kahder Morel Diarra Rokiatou Koné-Kamaté Konan marc Koffi Department of Stomatology Maxillofacial and Facial Plastic Surgery University Hospital of Cocody Abidjan Republic of Cote dIvoire

Introduction: Palatal abscess or cellulitis of dental origin is a rare clinical form of circumscribed cellulitis that can sometimes pose a diagnostic problem. It is the consequence of poor or non-treatment of dental caries or trauma. The aim of this study is to describe the clinical and therapeutic aspects of these two cases of palatal cellulitis of post-traumatic dental origin. Observation: The patients consulted for painful palatal swelling secondary to untreated dental trauma of the 21s. The diagnosis of palatal cellulitis was based on the inflammatory and fluctuating nature of the swelling. A probabilistic bi-antibiotic treatment and an incision and drainage associated with treatment of the portal of entry were carried out. Progression was favourable in both cases. Conclusion: Palatal cellulitis is a rare condition and can be prevented by systematic stomatological consultation after dental trauma. Diagnosis is clinical. However, CT scans are sometimes useful. The course is generally favorable with appropriate treatment.

关键词： Abscess Palate Dental Trauma

Spinal Analgesia with Intrathecal Morphine versus Conventional Analgesia after Laparoscopic Colectomy: A Retrospective Cohort Study

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Open Journal of Anesthesiology 2024年第7期14卷 159-174页

作者： Lionel Diyamona Manon Colin marc Léone Laurent Zieleskiewicz Joseph Nsiala Wilfrid Mbombo Rachel Mbala Bruno Pastene Chris Nsituavibidila Dan Kankonde Gracia Likinda Jean Claude Mubenga Khazy Anga Noelly Mukuna Christel Isengingo Department of Anaesthesia and Intensive Care University Clinics of Kinshasa University of Kinshasa Kinshasa Democratic Republic of the Congo Department of Anaesthesia and Intensive Care Marseilles Nord Hospital Marseille France General Hospital of Kinshasa ex Mama Yemo Kinshasa Democratic Republic of the Congo Department of Anaesthesia and Intensive Care Monkole Hospital Centre Kinshasa Democratic Republic of the Congo

Objective: Postoperative pain (POP) following abdominal surgery can vary from a few hours to several days. This acute, unrelieved pain can become chronic, requiring patients to take analgesics on an almost daily basis for comfort. Analgesia using general opioids has many side effects and intrathecal morphine is a good alternative. This study was conducted to evaluate the efficacy of intrathecal morphine (ITM) versus conventional analgesia in the management of postoperative pain in colectomy performed by laparoscopic surgery. Methods: Cohort study conducted at the Hôpital Nord in Marseille, from 01 January to 31 July 2021 in patients aged at least 18 years undergoing anaesthesia for scheduled colectomy by laparoscopic surgery. The primary endpoint was postoperative pain intensity and the secondary endpoints were morphine consumption, treatment side effects and length of hospital stay. Statistical analysis was performed using XLSTAT software. Results: We included 193 patients: 131 in the control group (conventional analgesia) and 62 in the ITM group. We observed: a significant decrease in pain (assessed by numerical scale) in favour of the ITM group in the post-anaesthetic care room, i.e. 3 (±4) vs 1 (±2), p 0 and H2: 2 (±2) vs. 1 (±2);p Conclusion: These results suggest that intrathecal morphine (ITM) in laparoscopic colectomy provides effective postoperative analgesia with low morphine consumption, and a reduction in morphine side-effects compared with conventional analgesia.

关键词： Intrathecal Morphine Colectomy Laparoscopy Conventional Analgesia

Bacteriological Profile of Infections Encountered in a Pneumology Service in a Moderate-Income Country [Pneumology Department of CHU Cocody (Côte d’Ivoire)]

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Open Journal of Respiratory Diseases 2024年第1期14卷 1-11页

作者： Brou Jean marcel Ahui Alitonde Eudoxie Djegbeton Alima Kone marc-Olivier Koffi Kouame Clarisse Elogne Mobio Nancy Hermine Benjamin Kouraogo Erick Akouatia Constante Virginie Brou-Gode Kigninlman Horo Boko Alexandre Kouassi Ngoran Koffi Pneumology Service Teaching Hospital of Cocody Abidjan C&#244te d’Ivoire Medical School of Abidjan University Félix Houphou&#235t Boigny Abidjan C&#244te d’Ivoire Pasteur Institute of Cô te d’Ivoire Abidjan C&#244te d’Ivoire

Introduction: Infections represent a real public health problem aggravating the morbidity and mortality of hospitalized patients. Methods: This was a retrospective study with descriptive purposes over a period of 05 years, in the Pneumology Department of the University Hospital of Cocody. Results: The average age in our population was 42 years. We observed a male predo- minance of 64.5%, with a sex ratio of 1.8. Medical history was dominated by HIV infection (23.5%), followed by tuberculosis (15.6%). Concerning lifestyle, smoking was found in 38% of cases. Symptoms progressed chronically in 80% of cases. An infectious syndrome was found in 75% of cases. Microbial culture was positive in 42% of cases. Pseudomonas aeruginosa and Klebsiella pneumoniae were encountered in 26.4% of cases each, followed by Echerichia coli in 10.4% of cases. Klebsiella pneumoniae in the first three years topped the list, but gradually. Pseudomonas aeruginosa maintained its leadership over the last three years. Pseudomonas aeruginosa isolates expressed a resistance rate of 9.8% to ceftazidime and 8.1% to imipenem;to aztreonam (36%), ticarcillin (33.3%) and levofloxacin. These strains were susceptible to fosfomycin (100%), mero- penem (96.6%) and amikacin (96%). For isolated strains of Entero- bacteria- ceae, resistance was observed about ticarcillin (83.3%) and amoxicillin clavula- nic acid (71.2%). Streptococcaceae showed resistance to tetracycline (69.2%) and erythromycin (50%). Over the years there has been an increase in re- sistance to amoxicillin-clavulanic acid ceftriaxone. The death rate was 14%. Conclusion: The bacterial profile of infections is dominated by germs respon- sible for nosocomial infection with significant mortality.

关键词： Bacterial Pleural Pneumonia Nosocomial Infection Sub-Saharan Africa Antibiotic Therapy

Impact of pre-existing cardiometabolic diseases on metastatic cancer stage at diagnosis:a prospective multinational cohort study

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Cancer Communications 2024年第5期44卷 593-597页

作者： Anna Jansana Aviane Auguste Marina Kvaskoff Agnès Fournier Emma Fontvieille Laia Peruchet-Noray Carine Biessy Reynalda Cordova Kristina Elin Nielsen Petersen Anne Tjoneland Verena Katzke Rudolf Kaaks Fulvio Ricceri Salvatore Panico Paolo Contiero Maria-Jose Sánchez Jesus Castilla Marta Crous-Bou Alicia Heath Elom Kouassivi Aglago Elisabete Weiderpass marc James Gunter Pietro Ferrari Elio Riboli Vivian Viallon Heinz Freisling International Agency for Research on Cancer(IARC-WHO) LyonFrance Paris-Saclay University University of Versailles-Saint-Quentin-en-YvelineUniversity Paris-SudFrench National Institute for Health and Medical Research(Inserm)Gustave Roussy“Exposome and Heredity”TeamCESPVillejuifFrance Department of Nutritional Sciences University of ViennaViennaAustria Danish Cancer Society Research Center CopenhagenDenmark Department of Public Health University of CopenhagenCopenhagenDenmark Division of Cancer Epidemiology German Cancer Research CentreHeidelbergGermany Department of Clinical and Biological Sciences University of TurinTurinItaly Unit of Epidemiology Regional Health Service ASL TO3GrugliascoTurinItaly Department of Clinical Medicine and Surgery Federico II UniversityNaplesItaly Environmental Epidemiology Unit Istituto di Ricovero e Cura a Carattere Scientifico(IRCCS)-Istituto Nazionale dei TumoriMilanItaly Cancer Registry of Granada Institute for Biosanitary Research of Granada(ibs.GRANADA)GranadaSpain Epidemiology and Control of Chronic Diseases Group Epidemiology and Public Health Networking Biomedical Research CentreMadridSpain Navarra Public Health Institute PamplonaSpain Unit of Nutrition and Cancer Cancer Epidemiology Research ProgramCatalan Institute of Oncology(ICO)-Bellvitge Biomedical Research Institute(IDIBELL)L’Hospitalet de LlobregatBarcelonaSpain Department of Epidemiology Harvard Tseng-Hsi Chan School of Public HealthBostonMassachusettsUSA Department of Epidemiology and Biostatistics School of Public HealthImperial College LondonSt Mary’s CampusNorfolk PlaceLondonUK

Owing to shared risk factors between cardiometabolic diseases(CMDs)and cancer,coupled with population aging,the lifetime risk of an individual developing cancer after a CMD is ***,biological mechanisms such as insulin resistance or inflammation may not only predispose individuals withCMDto an elevated risk of certain types of cancer but also to a diagnosis of cancer at an advanced stage[1,2].

关键词： diagnosis diseases cancer

Generalized Backward Doubly Stochastic Differential Equations Driven by Lévy Processes with Continuous Coefficients

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Acta Mathematica Sinica,English Series 2012年第10期28卷 2011-2020页

作者： Auguste AMAN Jean marc OWO UFR de Mathématiques et Informatique Université de Cocody

A new class of generalized backward doubly stochastic differential equations （GBDSDEs in short） driven by Teugels martingales associated with Levy process are investigated. We establish a comparison theorem which al... 详细信息

关键词： Backward doubly stochastic differential equations L@vy processes Teugels martingales comparison theorem continuous and linear growth conditions

Functionally Graded Dual-nanoparticulate-reinforced Aluminium Matrix Bulk Materials Fabricated by Spark Plasma Sintering

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Journal of Materials Science & Technology 2014年第8期30卷 736-742页

作者： Hansang Kwon marc Leparoux Akira Kawasaki Department of Materials System Engineering Pukyong National University365 Sinsenro608-759 BusanKorea Empa Swiss Federal Laboratories for Materials Science and TechnologyAdvanced Materials ProcessingFeuerwerkerstrasse 39CH-3602 ThunSwitzerland Department of Materials Processing Engineering Graduate School of EngineeringTohoku University980-8579 SendaiJapan

Functionally graded（FG） carbon nanotubes（CNT） and nano-silicon carbide（nSiC） reinforced aluminium（Al）matrix composites have been successfully fabricated using high-energy ball milling followed by solid-state spark plasma sintering *** CNTs were well-dispersed in the Al particles using the nSiC as a solid mixing *** different types of multi-walled CNTs were used to add different amounts of CNTs in the same *** ball milled Al—CNT—nSiC and Al—CNT powder mixtures were fully densified and demonstrated good adhesion with no serious microcracks and pores within an FG multilayer *** layer contained different amounts of the CNTs,and the nSiC additions showed different microstructures and *** is possible to control the characteristics of the FG multilayer composite through the efficient design of an Al—CNT—nSiC gradient *** concept offers a feasible approach for fabricating the dualnanoparticulate-reinforced Al matrix nanocomposites and can be applied to other scenarios such as polymer and ceramic systems.

关键词： Carbon nanotubes(CNT) Silicon carbide High-energy ball milling Spark plasma sintering(SPS) Functionally graded materials(FGM)