检索结果-南通市图书馆

World Journal of Biological Chemistry 2016年第1期7卷 14-43页

作者： Lisa Schmolz marc Birringer Stefan Lorkowski Maria Wallert Department of Nutritional Biochemistry and Physiology Institute of NutritionFriedrich Schiller University JenaGermany and Competence Center for Nutrition and Cardiovascular Health Department of Nutritional Food and Consumer StudiesUniversity of Applied Sciences

Bioavailability of vitamin e is influenced by several factors, most are highlighted in this review. While gender, age and genetic constitution influence vitamin e bioavailability but cannot be modified, life-style and intake of vitamin e can be. Numerous factors must be taken into account however, i.e., when vitamin e is orally administrated, the food matrix may contain competing nutrients. The complex metabolic processes comprise intestinal absorption, vascular transport, hepatic sorting by intracellular binding proteins, such as the significant α-tocopherol-transfer protein, and hepatic metabolism. The coordinated changes involved in the hepatic metabolism of vitamin e provide an effective physiological pathway to protect tissues against the excessive accumulation of, in particular, non-α-tocopherol forms. Metabolism of vitamin e begins with one cycle of CYP4F2/CYP3A4-dependent ω-hydroxylation followed by five cycles of subsequent β-oxidation, and forms the water-soluble end-product carboxyethylhydroxychroman. All known hepatic metabolites can be conjugated and are excreted, depending on the length of their sidechain, either via urine or feces. The physiological handling of vitamin e underlies kinetics which vary between the different vitamin e forms. Here, saturation of the side-chain and also substitution of the chromanol ring system are important. Most of the metabolic reactions and processes that are involved with vitamin e are also shared by other fat soluble vitamins. Influencing interactions with other nutrients such as vitamin K or pharmaceuticals are also covered by this review. All these processes modulate the formation of vitamin e metabolites and their concentrations in tissues and body fluids. Differences in metabolism might be responsible for the discrepancies that have been observed in studies performed in vivo and in vitro using vitamin e as a supplement or nutrient. To evaluate individual vitamin e status, the analytical procedures used for detect

关键词： Vitamin e metabolism Long-chain metabolites of vitamin e Vitamin e bioavailability Vitamin e transport

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

effect of emotional valence on episodic memory stages as indexed by event-related potentials

引用

World Journal of Neuroscience 2013年第4期3卷 250-262页

作者： marc e. Lavoie Kieron P. O’Connor Centre de Recherche Institut Universitaire en Santé Mentale de Montréal Montréal Canada&Département de Psychiatrie Université de Montréal Montréal Canada Département de Psychiatrie Université de Montréal Montréal Canada

Several investigations have shown that emotional events show superior recall than non-emotional ones. However, the cortical mechanisms underlying the episodic recall of emotional scenes are still poorly understood. Our main aim was to compare the magnitude of the event-Related brain Potentials (eRP) old-new effect related to emotionally unpleasant, pleasant and neutral photographic images. As expected, correct recognition of all types of images elicited three topographically distinct eRP components sensitive to the classical old-new recognition effect. The results revealed that the behavioral performances were mainly sensitive to arousal, while the eRP old/new effect over posterior regions (300 - 1000 ms) was exclusively affected by unpleasantness. A later component (1000 - 1400 ms) showed an inverted old/ new effect at parietal sites, which was also sensitive to unpleasantness. These results imply that eRP reflecting episodic conscious recollection and post-retrieval monitoring are clearly affected both by valence and arousal.

关键词： emotion Memory Familiarity Recollection Old/New effect event-Related Potentials

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Influence of gadolinium and dysprosium substitution on magnetic properties and magnetocaloric effect of Fe78-xRexSi4Nb5B12Cu1 amorphous alloys

引用

Journal of Rare earths 2020年第12期38卷 1317-1321页

作者： Lizhong Zhao Huacun Tian Xichun Zhong Zhongwu Liu Jean-marc Greneche R.V.Ramanujan Institute of Advanced Magnetic Materials Hangzhou Dianzi UniversityHangzhou 310012China School of Materials Science and engineering South China University of TechnologyGuangzhou 510640China Guangdong Institute of Special equipment Inspection and Research Guangzhou 528251China Institut des Molecules et Materiaux du Mans UMR CNRS 6283 Le Mans UniversiteAvenue MessiaenLe MansF-72085France School of Materials Science and engineering Nanyang Technological University639798Singapore Singapore-HUJ Alliance for Research and enterprise(SHARe) Nanomaterials for Energy and Energy-Water Nexus(NEW)Campus for Research Excellence and Technological Enterprise(CREATE)Singapore138602Singapore

Amorphous Fe78-xRexSi4 Nb5 B12Cu1(Re=Gd,Dy) ribbons with different Re contents were prepared by melt spinning to investigate the effect of heavy rare earth(Gd,Dy) substitution on the hyperfine structure,magnetic properties and magnetocaloric *** Curie temperature of Re substituted alloys,hyperfine field and magnetic moments of Fe atoms initially increase up to 1 at% Re content and then decrease monotonously for increasing Re content up to 10 at%.The dependence of magnetic entropy change(-△SM) and refrigeration capacity(RC) of the alloys on Re contents displays the same *** RCAReA values of the alloys substituted with 1 at% Gd and Dy are similar to those of recently reported Fe-based metallic glasses with enhanced RC values compared with those of Gd5 Ge1.9Si2 ***-△SM and RC values,negligible coercive force and hysteresis commonly make these Fe78-xRex-Si4 Nb5 B12Cu1 amorphous alloys as low-cost candidates for high-temperature magnetic refrigeration.

关键词： Magnetic properties Magnetocaloric effect Refrigeration capacity Rare earths

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Molecular Mechanism of CYTOSOLIC FeRRITIN Degradation and Iron release

引用

生物物理学报 2009年第S1期25卷 108-109页

作者： marc Mikhae Shan Soe-Lin Prem Ponka Lady Davis Institute for Medical Research Sir Mortimer B.Davis Jewish General Hospital and Departments of Physiology and Medicine McGill University 3755 Cote Ste-Catherine Road Montreal Quebec H3T 1E2 Canada

Ferritin sequesters and stores iron and, consequently, protect cells against iron-mediated free radical damage. However, the mechanism of iron exit from the ferritin nanocage and

关键词： cell Molecular Mechanism of CYTOSOLIC FeRRITIN Degradation and Iron release

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Transcatheter embolization therapy in liver cancer:an update of clinical evidences

引用

Chinese Journal of Cancer Research 2015年第2期27卷 96-121页

作者： Yi-Xiang J.Wang Thierry De Baere Jean-marc Idee Sebastien Ballet Department of Imaging and Interventional Radiology Faculty of MedicineThe Chinese University of Hong KongPrince of Wales Hospital Gustave Roussy Department of Interventional Radiology Guerbet Division of Research & Innovation

Transarterial chemoembolization （TACe） is a form of intra-arterial catheter-based chemotherapy that selectively delivers high doses of cytotoxic drug to the tumor bed combining with the effect of ischemic necrosis induced by arterial embolization. Chemoembolization and radioembolization are at the core of the treatment of liver hepatocellular carcinoma （HCC） patients who cannot receive potentially curative therapies such as transplantation, resection or percutaneous ablation. TACe for liver cancer has been proven to be useful in local tumor control, to prevent tumor progression, prolong patients＇ life and control patient symptoms. Recent evidence showed in patients with single-nodule HCC of 3 cm or smaller without vascular invasion, the 5-year overall survival （OS） with TACe was similar to that with hepatic resection and radiofrequency ablation. Mthough being used for decades, Lipiodol~ （Lipiodol~ Ultra Fluid~, Guerbet, France） remains important as a tumor-seeking and radio-opaque clrug delivery vector in intervendonal oncology. There have been efforts to improve the delivery of chemotherapeutic agents to tumors. Drug-eluting bead （DeB） is a relatively novel drug delivery embolization system which allows for fixed dosing and the ability to release the anticancer agents in a sustained manner. Three DeBs are available, i.e., Tandem~ （CeloNova Biosciences Inc., USA）, DC-Beads~ （BTG, UK） and HepaSphere~ （BioSphere Medical, Inc., USA）. Transarterial radioembolization （TARe） technique has been developed, and proven to be efficient and safe in advanced liver cancers and those with vascular complications. Two types of radioembolization microspheres are available i.e., SIR-Spheres~ （Sirtex Medical Limited, Australia） and TheraSphere~ （BTG, UK）. This review describes the basic procedure of TACe, properties and efficacy of some chemoembolization systems and radioembolization agents which are commercially available and/or currently under clinical evaluation. The key clinical tr

关键词： Transarterial chemoembolization hepatocellular carcinoma (HCC) drug-eluting particles microspheres Lipiodol radioembolization yttrium-90

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Mapping mountain areas: learning from Global, european and Norwegian perspectives

引用

Journal of Mountain Science 2019年第1期16卷 1-15页

作者： Martin F.PRICe Tor ARNeSeN erik GL?eRSeN marc J.MeTZGeR Centre for Mountain Studies Perth College University of the Highlands and Islands Mountain Research Programme Eastern Norway Research Institute Spatial Foresight Territorial Policy Support and Research Research Institute of Geography and the Lived environment School of GeoSciences University of Edinburgh

Defining the spatial extent of mountain areas has long been a challenge. In the present century, the availability of digital elevation models(DeMs) incorporated into geographic information systems(GIS) has allowed the definition of mountain areas based on topographic and other criteria. This paper presents the various delineations of mountains that have been prepared at three scales – global, regional(europe), and national – and explores the reasons and processes leading to these delineations, and how they have been used. A detailed case study is then presented for Norway. Overall, two types of approaches to mapping mountains have been taken: first, considering mountains per se, based on elevation and/or topography; second, considering them among other categories, e.g., landforms or biogeographical, environmental or landscape zones. All attempts to map mountain areas derive essentially from the objectives of those commissioning and/or undertaking the work; a unitary definition remains unlikely.

关键词： Mountains Mapping Geographic information systems europe Norway Topography

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

A power supply module for autonomous portable electronics:ultralow-frequency MeMS electrostatic kinetic energy harvester with a comb structure reducing air damping

引用

Microsystems & Nanoengineering 2018年第1期4卷 128-140页

作者： Yingxian Lu Frédéric Marty Dimitri Galayko Jean-marc Laheurte Philippe Basset UniversitéParis-est ESYCOM(EA2552)CNAMESIEE Paris and UPEMLVNoisyle-Grand 93162France Sorbonne Université LIP6 labCIAN groupJussieu campusParis 75005France UniversitéParis-est ESYCOM(EA2552)CNAMESIEE Paris and UPEMLVMarne-la-Vallée 77420France

A MeMS electrostatic kinetic energy harvester(e-KeH)of about 1 cm2,working at ultralow frequency(1–20 Hz),without any supported additional mass on its mobile electrode,and working even without a vacuum environment is *** prototype is especially suitable for environments with abundant low frequency motions such as wearable *** proposed e-KeH consists of a capacitor with a finger-teeth interdigited comb *** greatly reduces the air damping effect,and thus the capacitance variation remains important regardless of the presence of *** the new design,the energy transduced per cycle of excitation is no less than 33 times higher than the classic design within 10–40 Hz/2 g_(peak),while is 85 times higher at 15 Hz/2 g_(peak).An enclosed miniature ball combined with non-linear stoppers enables the oscillation of the movable electrode through impact-based frequency up-conversion mechanism,which is also improved by the low air *** to this new design,a higher efficiency than the classic gap-closing comb structure is obtained,as a larger range of working frequency(1–180 Hz)in air.A maximum energy conversion of 450 nJ/cycle is obtained with a bias voltage of 45 V and an acceleration of 11 Hz,3 g_(peak).Working with a diode AC-DC rectifier,the proposed KeH is able to support up to 3 RFID communications within 16 s while operated at 11 Hz,3 g_(peak).

关键词： autonomous kinetic electrostatic

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Finite-Size Conformational Transitions: A Unifying Concept Underlying Chromosome Dynamics

引用

Communications in Theoretical Physics 2014年第10期61卷 607-616页

作者： Bertrand R.Caré Pascal Carrivain Thierry Forné Jean-marc Victor Annick Lesne Laboratoire de Physique Théorique de la Matière Condensée CNRS UMR 7600UPMC University Paris 06F-75005ParisFrance CNRS GDR 3536 UPMC University Paris 06F-75005ParisFrance Institut de Génétique Humaine CNRS UPR 1142 MontpellierFrance Institut de Génétique Moléculaire de Montpellier CNRS UMR 5535University of MontpellierMontpellierFrance Kavli Institute for Theoretical Physics China CAS

Investigating average thermodynamic quantities is not sufficient to understand conformational transitions of a finite-size polymer. We propose that such transitions are better described in terms of the probability distribution of some finite-size order parameter, and the evolution of this distribution as a control parameter varies. We demonstrate this claim for the coil-globule transition of a linear polymer and its mapping onto a two-state model. In a biological context, polymer models delineate the physical constraints experienced by the genome at different levels of organization,from DNA to chromatin to chromosome. We apply our finite-size approach to the formation of plectonemes in a DNA segment submitted to an applied torque and the ensuing helix-coil transition that can be numerically observed, with a coexistence of the helix and coil states in a range of parameters. Polymer models are also essential to analyze recent in vivo experiments providing the frequency of pairwise contacts between genomic loci. The probability distribution of these contacts yields quantitative information on the conformational fluctuations of chromosome regions. The changes observed in the shape of the distribution when the cell type or the physiological conditions vary may reveal an epigenetic modulation of the conformational constraints experienced by the chromosomes.

关键词： coil-globule transition helix-coil transition chromosome conformational capture two-state model

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Schematic capture with MicroSim PSpice 3rd ed

Schematic capture with MicroSim PSpice

引用

1998年

作者： Herniter marc e

来源：畅想之星图书光盘版（南... 评论

在线全文

畅想之星图书光盘版（南通市图书馆镜像）

学校读者我要写书评

暂无评论

A ReVIeW OF THe SUSTAINABILITY OF ReSIDeNTIAL HOT WATeR INFRASTRUCTURe:PUBLIC HeALTH,eNVIRONMeNTAL IMPACTS,AND CONSUMeR DRIVeRS

引用

Journal of Green Building 2011年第4期6卷 77-95页

作者： Randi H.Brazeaua marc A.edwardsb Virginia Tech 418 Durham HallBlacksburgVAUSA 24060

Residential water heating is linked to the primary source of waterborne disease outbreaks in the United States,and accounts for greater energy demand than the combined water/wastewater utility ***,home water heating is the second largest energy consumer in the home and thus represents an integral part of the water-energy *** date,there has been little practical research that can guide decision-making by consumers,public health officials and regulators with regards to water heater selection and operation to minimize energy costs and the likelihood of waterborne *** uncertainties associated with existing“green”advice have potentially created misguided policy with long-term negative *** review is aimed at defining the current state of knowledge related to hot water infrastructure and in highlighting current gaps in the *** there are many sustainability claims of certain water heater types(i.e.,hot water recirculation systems and instantaneous water heaters)these claims have not been substantiated in head-to-head testing of the interplay between water temperature,energy,microbial growth,and scaling,all measures that need to be better defined.

关键词： water heaters energy water-energy nexus sustainable design green energy premise plumbing pathogens

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：