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Endophytic Occupation in Nodules of rhynchosia plants from Semiarid regions of Argentina

phyton-International Journal of Experimental Botany 2024年第6期93卷 1081-1099页

作者： Cinthia T.Lucero mar.a de los Á.ruíz Fabiola pagliero Carolina Castaño mariela L.Ambrosino Graciela S.Lorda Facultad de Ciencias Exactas y Naturales Universidad Nacional de La PampaRuta Nacional 35km 330Santa RosaLa PampaCP6300Argentina INTA EEA Anguil“Ing.Agr.Guillermo Covas”ruta Nacional 5 km 580AnguilLa PampaCC116326Argentina

Beneﬁcial microbes can improve soil health by promoting soil structure,nutrient cycling,and disease *** addition,a wide array of rhizospheric microbes are responsible for producing metabolically active compounds including various types of plant growth ***,microbial biodiversity studies could contribute to the improvement of agricultural practices in deprived areas,such as the pampean semiarid *** vast majority of studies conducted on endophytic microorganisms have focused on intensive crop legume *** contrast,little attention has been paid to microorganisms of native legumes,whose ecology is not directly affected by human *** this study,endophytic microorganisms isolated from root nodules of a selected native legume of the genus rhynchosia were *** isolates were studied with a focus on their plant growth-pro-moting rhizobacteria(pGpr)*** the edaphic characteristics of the pampean semiarid region,the isolates obtained were evaluated for their ability to grow under three salt stress conditions(50,100,and 200 mM NaCl)and four different pH values(6,7,8,and 9).Based on their pGpr activities,the selected strains were phylogenetically grouped using *** results showed great variability among the isolates in terms of the characteristics *** legumes manifested a wide endophytic variability and remar.able perfor-mance in pGpr *** conclude that they could be used as potential bioinoculants for legume cultivation,an excellent alternative to the use of chemical fertilizers that currently pollute the environment.

关键词： Native strains endophytes pGpr native legumes stress

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research foresight in bridging open science and open innovation:Overview based on the complex thinking paradigm

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International Journal of Innovation Studies 2024年第1期8卷 59-75页

作者： Jorge Sanabria-z marco Cr.z-Sandoval Athziri Moreno-romo Sofía Bosch-Gómez mar.a Soledad ramír.z-Montoya Institute for the Future of Education Tecnologico de MonterreyZapopan45201Mexico Central Bohemian Innovation Center(SIC) PragueCzech Republic The Burnes Center for Social Change Northeastern UniversityBostonMA02115USA Institute for the Future of Education Tecnologico de MonterreyMonterrey64700Mexico

Open innovation benefits from access to cutting-edge discoveries to increase their transformation into tangible applications for the benefit of *** research quality has been proposed as a primary objective of open science by the United Nations,to increase science reproducibility,impact,and trust,leading to robust decision-making and ***,opening access to data and processes is insufficient for researchers to achieve open innovation in the context of globalization,for example,by gathering insights from external and internal *** the appropriate mindset to manage complexity and generate synergy among researchers in academia,industry,and the government is essential to catalyze knowledge and transform it into relevant innovations for *** gain insights into the roles and challenges of researchers aiming to bridge the gap between open science and open innovation,a decade-plus Mapping Literature review was conducted based on the complex thinking *** thinking allows for novel connections of the information collected through open science and open innovation,considering different forms of engaging with alternative means of knowledge creation that may promote innovative and critical *** findings revealed:a)broad positioning of the terms in the European Union;b)open access and open data as current driving themes;c)a constant trade-off between the terms“open data”and“information protection”;d)lack of studies on researchers’complex thinking to help them manage openness;e)absence of the environmental helix in the initiatives;and(f)challenges in innovative communication and collaborative practices among public and private ***,we identified an opportunity to develop researchers’complex thinking such that the openness of information becomes a shared responsibility among partners across multiple *** shared responsibility can have methodological implications that permeate how open science and ope

关键词： Open innovation Open science Complex thinking Ecosystems research enhancement Educational innovation Higher education

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Body Contour in the post-Bariatric Male patient

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Modern plastic Surgery 2024年第2期14卷 15-22页

作者： Erick zúñiga-Garza Israel Salgado-Adame Claudio D. rojas-Gutiérr.z Laura mar.a rodríguez-Barrios Guillermo Álvar.z-Sánchez Eduardo Camacho-Quintero Department of plastic Surgery National Medical Center &#822020 de Noviembre&#8221 Mexico City Mexico

Background: Obesity is currently considered a public health problem. Bariatric procedures have become an important part of obesity management and, consequently, the number of male patients seeking post-bariatric reconstructive procedures have increased. Therefore, the clinical approach and understanding of the body contour of this population have become more relevant. The goal of post-bariatric reconstruction is to enhance the male silhouette through removal of skin and adipose tissue excess, and abdominal rectus diastasis repair. Material and Methods: We conducted a retrospective study at the plastic and reconstructive Surgery Department of the National Medical Center “20 de Noviembre”. All male patients referred to our department to start a post-bariatric reconstruction protocol from January 2018 to December 2022 were included in this study. results: In total, 15 patients who underwent corporal contouring procedures were included;median age was 49.2 years with minimum of 33 years, and a maximum of 57 years. Median Body mass index was 28.4 kg/mp>2p> with minimum of 22 kg/mp>2p> and maximum of 38 kg/mp>2p>. All patients were treated 18 months after their bariatric surgery. All patients underwent an abdominoplasty as a body contouring procedure. 4 (26.7%) patients presented complications related to the surgery. Conclusion: We described a comprehensive and systematic approach to massive weight loss for male patients, suggesting an abdominal marking based on the patient’s clinical features and the expected results avoiding feminization of the abdominal body contour.

关键词： Massive Weight Loss post-Bariatric Male Abdominoplasty Contouring

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Dietary(poly)phenol intake is associated with cardiometabolic health parameters in adolescents

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Food Science and Human Wellness 2024年

作者： Emily p.Laveriano-Santos Sara Castro-Barquero Camila Arancibia-riveros Ana mar.a ruiz-León rosa Casas ramón Estruch patricia Bodega Mercedes de Miguel Amaya de Cos-Gandoy Jesús martínez-Gómez Gloria Santos-Beneit Juan M.Fernández-Alvira rodrigo Fernández-Jiménez rosa M.Lamuela-raventós Anna Tresserra-rimbau The zena and Michael A.Wiener Cardiovascular Institute， Icahn School of Medicine at Mount Sinai Department de Nutrició， Ciències de l'Alimentació I Gastronomia， XIA， Facultat de Farmàcia i Ciències de l'alimentació， Institut de recerca en Nutrició i Seguretat Alimentària (INSA-UB)， Universitat de Barcelona Department of Internal Medicine， Hospital Clínic， Institutd'Investigacions Biomèdiques August pi I Sunyer (IDIBApS)， University of Barcelona Consorcio CIBEr， M.p.Fisiopatología de la Obesidad y Nutrición (CIBErObn)， Instituto de Salud Carlos III (ISCIII) Mediterranean Diet Foundation 5. Foundation for Science， Health and Education (SHE) 6. Centro Nacional de Investigaciones Cardiovasculares (CNIC) CIBEr de Enfermedades Cardiovasculares (CIBErCV) 9. Hospital Universitario Clínico San Carlos

Background: The protective role of (poly)phenols against metabolic disorders has been extensively studied in adults but not in ***: To assess associations of dietary (poly)phenols and their subclasses with cardiometabolic health parameters in adolescents. Methods: A cross-sectional study was conducted in 944 individuals aged 11 to 14 years enrolled in the SI! program for Secondary Schools trial (NCT03504059). (poly)phenol intake was assessed using semi-quantitative food frequency questionnaires and the phenol-Explorer database. The measured cardiometabolic parameters were waist circumference (WC) age-sex z-score， blood pressure (Bp) age-sex z-score， blood glucose (BG)， triglycerides (TG)， and high-density lipoprotein cholesterol (HDL-c). Multilevel mixed-effect linear regression models were applied to examine the association between (poly)phenol quintiles and cardiometabolic health ***: Compared to the lowest quintile， adolescents in the highest quintile of total (poly)phenol intake had lower WC z-scores (β=-0.09， 95%CI=-0.09;-0.08， p-for trend=0.002)， mean arterial pressure z-scores (β =-0.11， 95%CI=-0.12;-0.09， p-for trend=0.206)， and HDL-c (β=-1.52， 95%CI=-2.90;-0.14， p-for trend=0.108)， after multivariable adjustment. The WC z-scores (β=-0.11， 95%CI=-0.19;-0.03， p-for trend=0.013) and HDL-c (β=-2.16， 95%CI=-3.78;-0.53， p-for trend=0.046) were lower in the highest quintile of flavonoid intake compared to the lowest quintile. The highest quintile of phenolic acid intake was associated with a lower WC z-score (β=-0.14， 95%CI=-0.26;-0.02， p-for trend=0.011) and TG levels (β=-8.83， 95%CI=-12.37;-5.30， p-for trend r BG (β=-1.83， 95%CI= -3.103;-0.64， p-for trend p-for trend=0.034)， and with higher HDL-c (β=2.328， 95%CI= 1.40;3.17， p-for trend=0.466) compared to the lowest quintile. Conclusion: A higher intake of (poly)phenols， espe

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Carbon Dioxide/Methane Separation by Adsorption on Sepiolite

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Journal of Natural Gas Chemistry 2007年第3期16卷 235-243页

作者： José A.Delgado mar.a A.Uguina José L.Sotelo Beatr.z ruíz marcio rosário Department of Chemical Engineering Universidad Complutense de Madrid28040Madrid.Spain

In this work, the use of sepiolite for the removal of carbon dioxide from a carbon dioxide/methane mixture by a pressure swing adsorption （pSA） process has been researched. Adsorption equilibrium and kinetics have been measured in a fixed-bed, and the adsorption equilibrium parameters of carbon dioxide and methane on sepiolite have been obtained. A model based on the LDF approximation has been employed to simulate the fixed-bed kinetics, using the Langmuir equation to describe the adsorption equilibrium isotherm. The functioning of a pSA cycle for separating carbon dioxide/methane mixtures using sepiolite as adsorbent has also been studied. The experimental results were compared with the ones predicted by the model adapted to a pSA system. Methane with purity higher than 97% can be obtained from feeds containing carbon dioxide with concentrations ranging from 34% to 56% with the proposed pSA cycle. These results suggest that sepiolite is an adsorbent with good properties for its employment in a pSA cycle for carbon dioxide removal from landfill gases.

关键词： carbon dioxide methane sepiolite adsorption fixed-bed pressure swing adsorption

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Biodegradable stents in gastrointestinal endoscopy

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World Journal of Gastroenterology 2014年第9期20卷 2212-2217页

作者： Vicente Lorenzo-zú?iga Vicente Moreno-de-Vega Ingrid marín Jaume Boix Endoscopy Unit Department of Gastroenterology Hospital Universitari Germans Trias i Pujol 08916 Badalona Spain Centro de Investigación Biomédica en red de Enfermedades Hepáticas y Digestivas (CIBErEHD) 08916 Badalona Spain

Biodegradable stents(BDSs)are an attractive option to avoid ongoing dilation or surgery in patients with benign stenoses of the small and large *** experience with the currently the only BDS for endoscopic placement,made of poly-dioxanone,have shown promising *** some aspects should be improved as are the fact that BDSs lose their radial force over time due to the degradable material,and that can cause stent-induced mucosal or parenchymal *** complication rate and modest clinical efficacy has to be carefully considered in individual patients prior to placement of ***,the price of these stents therefore it is nowadays an important limitation.

关键词： Biodegradable stents Strictures Endoscopy Endoscopic placement Stenoses

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The First pilot Epigenetic Type Improvement of Neuropsychiatric Symptoms in a polymorphic Dopamine D2 (-DrD2/ANKK (Taq1A)), OprM1 (A/G), DrD3 (C/T), and MAOA (4r) Compromised preadolescence Male with putative pANDAS/CANS: positive Clinical Outcome with precision-Guided DNA Testing and pro-Dopamine regulation (KB220) and Antibacterial Therapies

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Open Journal of Immunology 2024年第3期14卷 60-86页

作者： Kenneth Blum Igor Elman David Han Colin Hanna David Baron Ashim Gupta Shan Kazmi Jag Khalsa Debasis Bagchi Thomas McLaughlin rajendra D. Badgaiyan Edward J. Modestino Drew Edwards Catherine A. Dennen Eric r. Braverman Abdalla Bowirrat Keerthy Sunder Kevin Murphy Nicole Jafari Foojan zeine paul r. Carney mark S. Gold Kai-Uwe Lewandowski Alir.za Sharafshah Aryeh r. pollack panayotis K. Thanos Division of Addiction research & Education Center for Sports and Mental Health Western University of Health Sciences Pomona CA USA Department of psychiatry Boonshoft School of Medicine Wright State University and Dayton VA Medical Centre Dayton OH USA Division of Nutrigenomics Victory Nutrition International Lederoch PA USA Institute of psychology ELTE Etvs Lornd University Budapest Hungary Department of psychiatry School of Medicine University of Vermont Burlington VT USA The Kenneth Blum Behavioral & Neurogenetic Institute LLC. Austin TX USA Department of Molecular Biology Adelson School of Medicine Ariel University Ariel Israel Division of Neuromodulation research Karma Doctors & Karma TMS Palm Springs CA USA Division of personalized Interventions Peak Logic Del Mar CA USA Division of personalized Medicine Cross-Cultural Research & Educational Institute San Clemente CA USA Awareness Integration Institute San Clemente CA USA Division of personalized pain Therapy Center for Advanced Spine Care of Southern Arizona Tucson AZ USA Department of psychiatry Harvard School of Medicine Cambridge MA USA Department of Management Science and Statistics University of Texas San Antonio TX USA Behavioral Neuropharmacology and Neuroimaging Laboratory Clinical Research Institute on Addictions Department of Pharmacology and Toxicology Jacobs School of Medicine and Biomedical Sciences University at Buffalo Buffalo NY USA Future Biologics Lawrenceville GA USA Department of Microbiology Immunology & Tropic Diseases School of Medicine Georgetown University Washington DC USA Department of pharmaceutical Sciences College of Pharmacy Texas Southern University Houston TX USA Department of psychiatry School of Medicine Case Western University Cleveland OH USA Brain and Behavior Laboratory Curry College Milton MA USA The Neurogenesis project Jacksonville FL USA Department of Family Medicine Jefferson Health Northeast Philadelphia PA USA Departmen

pediatric autoimmune neuropsychiatric disorders associated with or without streptococcal and other bacterial infections (pANDAS/CANS) are emerging as a featured pediatric disorder. Although there is some controversy regarding treatment approaches, especially related to the behavioral sequelae, we have hypothesized in other published work that it is character.zed by the rapid onset of reward Deficiency Syndrome (rDS) in children. We propose utilizing a multi-systems biological approach involving the coupling of genetic addiction risk testing and pro-dopamine regulation (KB220/pOLYGEN®) to help induce “dopamine homeostasis” in patients with pANDAS, especially those with known DNA-induced hypodopaminergia. This case study examines a 12-year-old Caucasian male with no prior psychiatric issues who presented with a sudden onset of severe anxiety, depression, emotional liability, and suicidal ideation. The patient underwent genotyping and the genetic addiction risk score (GArS) testing, which revealed risk polymorphisms in the dopamine D2 (-DrD2/ANKK (Taq1A), OprM1 (A/G), DrD3 (C/T), and MAOA (4r) genes. These polymorphisms have been linked to hypodopaminergia. The patient was subsequently placed on research ID-KB220zpBMpOLY (pOLYGEN®), and albeit the possibility of bias, based upon self and parental assessment, a marked rapid improvement in psychiatric symptoms was observed. In the second phase of treatment (102 days utilizing KB220), the patient received standard antibody testing, which was positive for Lyme. Antibacterial therapy started immediately, and KB220z was discontinued to provide a wash-out period. A monotonic trend analysis was performed on each outcome measure, and a consistently decreasing trend was observed utilizing antibacterial therapy. Our recommendation, albeit only one case, is to utilize and further research a combined therapeutic approach, involving precision-guided DNA testing and pro-dopamine regulation along with antibacterial therapy, as well as

关键词： pANDAS CANS Genetic Addiction risk Testing (GArS) pro-Dopamine regulation Hypodopaminergia polymorphisms Antibacterial Therapy Infections

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Endoscopic submucosal dissection training with pig models in a Western country

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World Journal of Gastroenterology 2010年第23期16卷 2895-2900页

作者： Adolfo parra-Blanco mar.a rosa Arnau David Nicolás-pér.z Antonio z Gimeno-García Nicolás González Juan A Díaz-Acosta Alejandro Jiménez Enrique Quintero Department of Gastroenterology University Hospital of the Canary Islands Ofra s/n Endoscopy Unit Department of GastroenterologyAsturias Central University HospitalCelestino Villamil s/n research Animal Laboratory Ofra s/nLa Laguna University Department of Gastroenterology Montevideo Clinic HospitalAvda Italia s/n research Unit University Hospital of the Canary IslandsOfra s/n

AIM:To test a strategy for endoscopic submucosal dissection(ESD) training in animal models designed to overcome the initial learning ***:ESD was attempted in ex vivo and in vivo pig *** ESD procedures were attempted in the esophagus(n=9) or the stomach(n=21).The ex vivo model was used until initial competence was *** the in vivo model,several ESD procedures were performed in up to 3 *** following variables were analyzed:specimen size,complete and en bloc resection rate,time for circumferential incision,time for submucosal dissection,total ESD duration,and ***:Complete resection was achieved in 28 cases(en bloc 27);2 could not be completed(one perforation,one technical diff iculty).The mean ± SD time for circumferential incision was 36.2±16.8 min(range:8-87 min),and the mean±SD time for submucosal dissection was 45.1±35.7 min(range:9-196 min).The mean±SD size of the resected specimens was 45.2±17.8 *** mean±SD total resection time was signif icantly increased for the gastric cases performed in the f irst half of the study(n=13) than in the second half(n=8)(98.9±62.4 min vs 61.7±17.6 min,p=0.04),although the specimen size did not ***:Training in animal models could help endoscopists overcome the learning curve before starting ESD in humans.

关键词： Endoscopic submucosal dissection Training Animal model

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Effects of cellulase and xylanase enzymes mixed with increasing doses of Salix babylonica extract on in vitro rumen gas production kinetics of a mixture of corn silage with concentrate

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Journal of Integrative Agriculture 2015年第1期14卷 131-139页

作者： Abdelfattah z M Salem German Buendía-rodríguez Mona M M Elghandour mar.a A mariezcurrena Berasain Francisco J pea Jiménez Alberto B pliego Juan C V Chagoyán mar.a A Cerrillo Miguel A rodríguez Faculty of Veterinary Medicine and Animal Science Autonomous University of the State of Mexico National Center of Disciplinary research in Animal physiology and Improvement INIFAP Ajuchitlán Institute of Agricultural Sciences Autonomous University of HidalgoEx-Hda. of Aquetzalpa Faculty of Veterinary Medicine and Animal Science Juárez University of the Durango State

An in vitro gas production （Gp） technique was used to investigate the effects of combining different doses of Salix babylonica extract （SB） with exogenous fibrolytic enzymes （Ez） based on xylanase （X） and cellulase （C）, or their mixture （XC; 1：1 v/v） on in vitro fermentation characteristics of a total mixed ration of corn silage and concentrate mixture （50：50, w/w） as substrate. Four levels of SB （0, 0.6, 1.2 and 1.8 mL g-1 dry matter （DM）） and four supplemental styles of Ez （1 μL g-1 DM; control （no enzymes）, X, C and XC （1：1, v/v） were used in a 4×4 factorial arrangement. In vitro Gp （mL g-1 DM） were recorded at 2, 4, 6, 8, 10, 12, 24, 36, 48 and 72 h of incubation. After 72 h, the incubation process was stopped and supernatant pH was determined, and then filtered to determine dry matter degradability （DMD）. Fermentation parameters, such as the 24 h gas yield （GY24）, in vitro organic matter digestibility （OMD）, metabolizable energy （ME）, short chain fatty acid concentrations （SCFA）, and microbial crude protein production （MCp） were also estimated. results indicated that there was a SBxEz interaction （p〈0.0001） for the asymptotic gas production （b）, the rate of gas production （c）, Gp from 6 to 72 h, Gp2 （p=0.0095）, and Gp4 （p=0.02）. The SB and different combination of enzymes supplementation influenced （p〈0.001） in vitro Gp parameters after 12 h of incubation; the highest doses of SB （i.e., 1.8 mL g-1 DM）, in the absence of any Ez, quadratically increased （p〈0.05） the initial delay before Gp begins （L） and Gp at different incubation times, with lowering b （quadratic effect, p〈0.0001 ） and c （quadratic effect, p〈0.0001 ; linear effect, p=0.0018）. The Gp was the lowest （p〈0.05） when the highest SB level was combined with cellulose. There were SBxEz interactions （p〈0.001） for OMD, ME, the partitioning factor at 72 h of incubation （pF72）, GY24, SCFA, MCp （p=0.0143）, and pH （p=0.0008）. The OMD, ME, GY24 and SCFA with supplementation of SB extract at 1.8 mL g-1 DM were h

关键词： cellulase degradability gas production Salix babylonica xylanase

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Comparison of Snellen and Early Treatment Diabetic retinopathy Study charts using a computer simulation

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International Journal of Ophthalmology(English edition) 2016年第1期9卷 119-123页

作者： reuben r.Shamir Yael Friedman Leo Joskowicz Michael Mimouni Eytan z.Blumenthal School of Engineering and Computer Science the Hebrew University Department of Ophthalmology Hadassah-Hebrew University Medical Center Department of Ophthalmology Rambam Medical Center

AIM：To compare accuracy,reproducibility and test duration for the Snellen and the Early Treatment Diabetic retinopathy Study（ETDrS）charts,two main tools used to measure visual acuity（VA）.·M ETHODS：A computer simulation was programmed to run multiple virtual patients,each with a unique set of assigned parameters,including VA,false-positive and false-negative error *** each virtual patient,assigned VA was randomly chosen along a continuous scale spanning the range between 1.0 to 0.0 log mar units（equivalent to 20/200 to 20/20）.Each of 30 000virtual patients were run ten times on each of the two VA charts.·rESULTS：Average test duration（expressed as the total number of characters presented during the test±SD）was12.6±11.1 and 31.2±14.7 characters,for the Snellen and ETDrS,***,defined as the absolute difference（±SD）between the assigned VA and the measured VA,expressed in log mar units,was superior in the ETDrS charts：0.12±0.14 and 0.08±0.08,for the Snellen and ETDrS charts,***,expressed as test-retest variability,was superior in the ETDrS charts：0.23±0.17 and 0.11±0.09 log mar units,for the Snellen and ETDrS charts,respectively.·CONCLUSION：A comparison of true（assigned）VA to measured VA,demonstrated,on average,better accuracy and reproducibility of the ETDrS chart,but at the penalty of significantly longer test *** differences were most pronounced in the low VA *** reproducibility using a simulation approach is in line with reproducibility values found in several clinical studies.

关键词： Early Treatment Diabetic retinopathyStudy Snellen computer simulation visual acuity testing virtual patients

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