检索结果-南通市图书馆

Evaluation of the Mechanisms Acting on the Atlantic Meridional Overturning Circulation in CESM2 for the 1pctCO_(2) Experiment

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Atmospheric Science Research 2024年第1期7卷 40-58页

作者： Lívia Sancho Elisa Passos marcio Cataldi Luiz Paulo de freitas Assad Luiz Landau Laboratory of Computational Methods in Engineering Civil Engineering ProgramAlberto Luiz Coimbra Institute for Graduate Studies and Research in EngineeringFederal University of Rio de JaneiroRio de Janeiro21941-617Brazil Civil Engineering Program Alberto Luiz Coimbra Institute for Graduate Studies and Engineering ResearchFederal University of Rio de JaneiroRio de Janeiro21941-617Brazil Physical Oceanography Laboratory Department of Physical OceanographyFaculty of OceanographyRio de Janeiro State UniversityRio de Janeiro20559-900Brazil Climate System Monitoring and Modeling Laboratory Water Resources and Environmental EngineeringFluminense Federal University24020-140Brazil Regional Atmospheric Modeling Group(mar) Physics of the EarthDepartment of PhysicsRegional Campus of International Excellence(CEIR)“Campus Mare Nostrum”University of MurciaMurcia30100Spain Department of Meteorology Institute of GeosciencesFederal University of Rio de JaneiroRio de Janeiro21941-617Brazil

The Atlantic Meridional Overturning Circulation(AMOC)is a crucial component of the Earth’s climate system due to its fundamental role in heat distribution,carbon and oxygen transport,and the *** climate components,such as the atmosphere and sea ice,influence the *** the physical mechanisms of those interactions is paramount to increasing knowledge about AMOC’s *** this study,the authors used outputs from the Community Earth System Model version 2 and observational data to investigate changes in theAMOC and the associated physical *** DECK experiments were evaluated:piControl and 1pctCO_(2),with an annual increase of 1%of atmospheric CO_(2).The analysis revealed a significant decrease in the AMOC,associated with changes in mixed layer depth and buoyancy in high latitudes of the North Atlantic,resulting in the shutdown of deep convection and potentially affecting the formation of North Atlantic Deep Water and Antarctic Bottom Water.A vital aspect observed in this study is the association between increased runoff and reduced water evaporation,giving rise to a positive feedback ***,the rates of freshwater spreading have intensified during this period,which could lead to an accelerated disruption of the AMOC beyond the projections of existing models.

关键词： AMOC Meridional cell Climate change Deep circulation CESM2 results CMIP6

Genetic Diversity of Accessions and First Generation Progeny of the Mangaba Genebank

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

American Journal of Plant Sciences 2018年第8期9卷 1618-1629页

作者： Adrielle Naiana Ribeiro Soares Debora Clivati marília.freitas de Vasconcelos Melo Matthew Gitzendanner Pamela Soltis Douglas Soltis Josué Francisco da Silva Júnior Ana da Silva Ledo Ana Veruska Cruz da Silva Federal University of Sergipe S&atilde o Cristovã o Brazil National Institute of Amazonian Research Manaus Brazil Federal University of Alagoas Maceió Brazil University of Florida Gainesville USA Embrapa Coastal Tablelands Aracaju Brazil

Mangaba (Hancornia speciose Gomes—Apocynaceae) is an important fruit tree in Brazil and has an unexplored stock germplasm collection. Commercial varieties are unavailable and little is known about its potential as a source of genetic diversity for molecular breeding programs. Progeny tests may improve studies on commercial variability and facilitate genetic improvement of the species. Our aim was to evaluate the genetic diversity and structure of accessions and progeny from the Mangaba Genebank of Embrapa Coastal Tablelands. We estimated the genetic diversity of 96 individuals using 4 SSR markers. The mean observed heterozygosity was lower than expected, showing an excess of homozygotes, corroborated by the positive coefficient of endogamy. The genetic diversity indexes (Fst) and Nei’s unbiased genetic identity (GI) revealed, in general, moderate genetic diversity between accessions. The relationship between matrices and progenies showed that there may be a greater degree of genetic information sharing between the ABP1 and ABP2 accessions. The Bayesian analysis suggested the presence of two distinct groups of genotypes (K = 2). These results will assist future breeding programs and facilitate the conservation of mangaba.

关键词： Hancornia speciose Gomes Brazilian Fruits Microsatellite markers Genetic Resources

A novel supplement with yeast b-glucan, prebiotic, minerals and Silybum mar.anum synergistically modulates metabolic and inflammatory pathways and improves steatosis in obese mice

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Integrative Medicine 2021年第5期19卷 439-450页

作者： Victor Abou Nehmi Gilson Masahiro Murata Ruan Carlos Macêdo de Moraes Gabriely Cristina AlvesLima Danielle Araujo De Miranda Katrin Radloff Raquel Galvao Figuerêdo Costa Joyce de Cassia Rosade Jesus Jéssica Alves De freitas Nayara Izabel Viana Ruan Pimenta Katia Ramos Moreira Leite JoséPinhata Otoch Ana Flávia mar.al Pessoa Laboratory of Medical Investigation(LIM-26) Department of SurgeryUniversity of Sao Paulo Medical SchoolSao PauloSP 01246903Brazil Laboratory of Medical Investigation(LIM-29) Clinic Medical DepartmentUniversity of Sao Paulo Medical SchoolSao PauloSP 01246903Brazil Department of Physiology Escola Paulista de Medicina/Universidade Federal de Sao PauloSP 04023062Brazil Max Rubner-Institut Federal Research Institute of Nutrition and FoodKarlsruheBW 76131Germany Cancer and Inflammation Program Center for Cancer ResearchNational Cancer InstituteNational Institutes of HealthBethesdaMD 20892United States Laboratory of Medical Investigation(LIM-55) Urology DepartmentUniversity of Sao Paulo Medical SchoolSao PauloSP 01246903Brazil D'Or Institute for Research and Education RJ 22281-100Brazil Program in Anesthesiology Surgical Sciencesand Perioperative MedicineUniversity of Sao PauloSao PauloSP 01246903Brazil Brazilian Academic Consortium for Integrative Health(CABSIN) Natural Products CommitteeSao PauloSP 05449-070Brazil

Objective: To evaluate the synergic effects of a novel oral supplement formulation, containing prebiotics,yeast b-glucans, minerals and silymarin(Silybum mar.anum), on lipid and glycidic metabolism, inflammatory and mitochondrial proteins of the liver, in control and high-fat diet-induced obese ***: After an acclimation period, 32 male C57 BL/6 mice were divided into the following groups:nonfat diet(NFD) vehicle, NFD supplemented, high-fat diet(HFD) vehicle and HFD supplemented. The vehicle and experimental formulation were administered orally by gavage once a day during the last four weeks of the diet(28 consecutive days). We then evaluated energy homeostasis, inflammation, and mitochondrial protein expression in these groups of ***: After four weeks of supplementation, study groups experienced reduced glycemia, dyslipidemia,fat, and hepatic fibrosis levels. Additionally, proliferator-activated receptor-α, AMP-activated protein kinase-1α, peroxisome proliferator-activated receptor γ co-activator-1α, and mitochondrial transcription factor A expression levels were augmented;however, levels of inhibitor of nuclear factor-κB kinase subunit a and p65 nuclear factor-κB expression, and oxidative markers were reduced. Notably, the cortisol/C-reactive protein ratio, a well-characterized marker of the hypothalamic–pituitary–adrenal axis immune interface status, was found to be modulated by the ***: We discovered that the novel supplement was able to modify different antioxidant, metabolic and inflammatory pathways, improving the energy homeostasis and inflammatory status, and consequently alleviated hepatic steatosis.

关键词： Supplement Silymarin Prebiotic Obese Mice Steatosis Inflammation Mitochondrial biogenesis

Long COVID: A Molecular, Cellular and Histopathology Overview

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Journal of Biosciences and Medicines 2023年第9期11卷 90-113页

作者： Bárbara Rafaela da Silva Barros Leonardo Carvalho de Oliveira Cruz Georon Ferreira de Sousa Guilherme Antonio Souza-Silva marília R. C. F. de Lima Elifrances G. Oliveira Anna Jéssica Duarte Silva Larissa S. Macêdo Lígia R. S. Leal Bianca F. São marcos Carolina Elsztein mar.a da Conceição V. Invenção Antonio Carlos de freitas Cristiane Moutinho-Melo Immunological and Antitumor Analysis Laboratory (LAIA) and Keizo Asami Immunopathology Laboratory Institute (iLIKA) Federal University of Pernambuco Recife Brazil Laboratory of Neuroendocrinology and Metabolism Federal University of Pernambuco Recife Brazil Laboratory of Molecular Studies and Experimental Therapy Federal University of Pernambuco Recife Brazil

Long COVID has been studied as different sequelae that some individuals can develop after the acute phase of the disease. Persistent symptoms such as dry cough, fatigue, and dyspnea can remain after six months of COVID-19 cure. Others such as lung fibrosis, kidney injury, and thrombotic risk also are observed. Here, a deep review of each human organ and system infected by the virus was performed aiming to show how molecules expression and cell signaling can induce the organism cure or injuries and, subsequently sequelae. The review also suggests the importance of public health surveillance for these cases including a more comprehensive analysis of molecular biology tools that can clarify and assist in the prognosis, treatment, and preventive methods for potentially more serious disorders in post-COVID-19 patients.

关键词： Long COVID COVID-19 Sequelae Public Health Surveillance