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Gender Differences in Comorbidities and Sleep Patterns of Obese Patients with Obstructive Sleep Apnea

World Journal of Neuroscience 2015年第1期5卷 49-57页

作者： Ricardo José Benício Valadares Klayton Galante Sousa marília nascimento espindola Carlos Eduardo Ventura Gaio dos Santos Carlos Alberto Assis Viegas Postgraduate School of Medicine at the University of Brasilia (UNB) Brasilia Brazil

Objective: The aim of the study was to compare the comorbidities and sleep patterns most commonly associated with each gender in obstructive sleep apnea (OSA). Methods: This was a cross-sectional study of obese individuals with OSA.?The polysomnographies were carried out in a sleep laboratory environment, using a 15-channel polysomnography setup. Airflow was measured using a nasal pressure cannula/thermistor combination. A standard handbook was used for interpretation of PSG findings. Results: A total of 284 subjects were included in the study, (147 females). The mean age, body mass index and neck circumference were similar between females and males (p?= 0.9579,?p??p?< 0.0001, respectively). On polysomnography, females exhibited longer latency to REM sleep (146.50 ± 85.93 vs. 122.3 ± 68.28,?p?= 0.0210) and a higher percentage of?delta sleep (10.09 ± 7.48 vs. 7.55 ± 6.57,?p?= 0.0037);males had more frequent microarousals (38.37?± 27.44 vs. 28.07 ± 21.23,?p?= 0.0017) and a higher AHI score (30.56 ± 27.52 vs. 17.31 ± 21.23,?p?< 0.0001). The comorbidities most commonly associated with female gender were diabetes (29% vs. 9.49%,?p?= 0.0132), hypothyroidism (20% vs. 2.19%,?p?< 0.0001), and depression (81.63% vs. 51.22%,?p?< 0.0001). Male gender was associated with myocardial infarction (6.57% vs. 1.38%,?p?= 0.0245) and alcohol intake (33.88% vs. 11.34%,?p?< 0.0001). Obese males with OSA have a larger?neck circumference and higher AHI and arousal indices than females. Conclusions: There are genderdifferences both in the sleep patterns and in the comorbidities of patients with OSA. Men had a larger neck circumference, higher apnea and sleep fragmentation scores, were more likely to consume alcohol, and were more likely to have a history of myocardial infarction than women.

关键词： Obstructive Sleep Apnea Obesity Gender Comorbidity

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Yeast-TiO<sub>2</sub>Biotemplate for Oxytetracycline Solar Photodecomposition

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Journal of Materials Science and Chemical Engineering 2020年第7期8卷 12-26页

作者： Nilce Ortiz Lucia nascimento Fernanda Maichin Izabela Rodrigues Cerqueira Lima Azevedo marília Guerino Vieira Institute for Nuclear and Energy Research—IPEN S&#227 o Paulo Brasil

The detection of the pharmaceutical compounds used in human and veterinary medicine is in several environmental matrices (surface waters, effluents, groundwater, soils, and sediments), and such presence promotes the resistance bacteria development, making them ineffective in some diseases treatment. The research project promotes the TiO2 synthesis using yeast culture as biotemplate, the step followed by the microstructure characterization with surface area enhancement;such properties are responsible for the improvement of solar photodecomposition processes of the veterinary antibiotic oxytetracycline. In such simple and standard process conditions the system reaches about 84% of removal percentage with a better agreement with the pseudo-first-order with the Pearson coefficient in the range from 0.82 to 0.94 and K1 = 0.035 M−1∙s−1. The degradation rate constant increased with the increasing initial Yeast-TiO2 dosage until the maximum mass of 0.1 g or with the decreasing of initial oxytetracycline concentration. The solar light used as a sustainable irradiation source is abundant and low cost in tropical countries, perfect to be applied in water treatment to decompose the pharmaceuticals pollutants, as the veterinarian antibiotics. The study demonstrates that solar photodecomposition is an efficient treatment technology for the removal of antibiotics from polluted water and provides insightful information on the potential practical application of this technology to treat contaminated water, possibly also in rural, distant areas.

关键词： Oxytetracycline Photodecomposition Bio Template Yeast Solar

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Oxytetracycline Water Contamination Treated with Biocarbon TiO2 and Solar Photodecomposition

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Journal of Agricultural Chemistry and Environment 2020年第4期9卷 299-313页

作者： Nilce Ortiz Izabela Rodrigues Cerqueira Lima Azevedo marília Guerino Vieira Fernanda Maichin Lucia nascimento Institute for Nuclear and Energy Research—IPEN S&#227 o Paulo SP Brasil

Reliable data of antibiotic use and environmental discharge as veterinary medicine are essential to help countries raise awareness of the appropriate use, control, and correct water release. The first approach is to change the regulatory framework based on consuming information, use policy, and discharge laws. The important research contribution is a novel water treatment process to treat, remove, and reduce antibiotic concentration in discharged water, mainly those used in the animal protein industry. The low particle biochar added during the titanium isopropoxide hydrolysis reduces the titanium dioxide (TiO2) agglomerates and promotes the adsorption surface process. Such improved catalyst material enhances the solar decomposition efficiency to 93% from original oxytetracycline with better correspondence with the Elovich kinetics, intraparticle diffusion, R-P isotherm, and Langmuir-Hinshelwood model.

关键词： Oxytetracycline Solar Photodecomposition Biocarbon Elovich Langmuir-Hinshelwood (L-H)

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Treatability studies of naphthalene in soil,water and air with persulfate activated by iron(Ⅱ)

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Journal of Environmental Sciences 2020年第4期32卷 67-77页

作者： Gabriela P.Mendes Vivian M.A.Magalhaes Lélia C·R·Soares Rayanne M.Aranha Claudio A.O.nascimento marilda M.G.R.Vianna Osvaldo Chiavone-Filho Department of Chemical Engineering University of Sao PauloSPf 05508-000Brazil Department of Chemical Engineering Federal University of Rio Grande Do NorteNatalRN59072-970Brazil

Chemical oxidation was applied to an artificially contaminated soil with naphthalene(NAP).Evaluation of NAP distribution and mass reduction in soil,water and air phases was carried out through mass *** of NAP distribution and mass reduction in soil,water and air phases was carried out through mass *** importance of the air phase analysis was emphasized by demonstrating how NAP behaves in a sealed system over a 4 hr reaction *** of Experiments method was applied to the following variables:sodium persulfate concentration[SP],ferrous sulfate concentration[FeS04],and *** system operated with a prefixed solid to liquid ratio of 1:*** following conditions resulted in optimum NAP removal[SP]=18.37 g/L,[FeSO4]=4.25 g/L and pH=*** the end of the 4 hr reaction,62%of NAP was *** the soil phase,the chemical oxidation reduced the NAP concentration thus achieving levels which comply with Brazilian and USA environmental *** the NAP partitioning view,the monitoring of each phase allowed the variabilities assessment over the process,refining the knowledge of mass *** on NAP distribution in the system,this study demonstrates the importance of evaluating the presence of semi-volatile and volatile organic compounds in the air phase during remediation,so that there is greater control of the system as to the distribution and presence of the contaminant in the *** results highlight the importance of treating the contaminant in all its phases at the contaminated site.

关键词： Chemical oxidation Phase distribution Degradation kinetics PAH Soil remediation Mass balance

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Chemical,Sensorial and Rheological Properties of a New Organic Rice Bran Beverage

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Rice science 2009年第3期16卷 226-234页

作者： Gerson Luis FACCIN Leila do nascimento VIEIRA Letícia Adélia MIOTTo Pedro Luiz Manique BARRETO Edna Regina AMANTE Department of Food Science and Technology University Federal of the Santa CatarinaRod Admar Gonzaga1346-Itacorubi FlorianópolisSCCEP 88034001Brazil

Rice bran is a solid residue from rice polishing that is used in animal nutrition and rice oil production. Cultivation conditions with agro-toxics, lipids instability, and tendency for mycotoxin contamination restrict its application in human nutrition. Therefore, organic agriculture is an alternative to use the properties of rice bran. Rice bran beverage is a new cereal product from organic rice. This work presents the preliminary results of the chemical and rheological studies of a bath pasteurized rice bran beverage. Compared with integral defatted milk, soy extracts, and brown rice low-fat milk, the rice bran beverage studied in this work presents itself as an important source of minerals and unsaturated lipids. All essential amino acids were found in this product. Glutamic and aspartic acids were predominant. Bath pasteurization at boiling water temperature for 15 and 30 min was adequate for microbiological safety. Refrigeration storage for 20 days, evaluated by pH and acidity variations, was ideal for assessment of the beverage conservation time. The beverage viscosity was of the Newtonian standard behavior, and its viscosity during storage was not a good parameter to evaluate shelf life. Sensory preference tests showed positive perspectives for this new beverage.

关键词： beverage composition residue rice bran viscosity

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Progress toward understanding the contribution of alkali generation in dental biofilms to inhibition of dental caries

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International Journal of Oral Science 2012年第3期4卷 135-140页

作者： Ya-Ling Liu marcelle nascimento Robert A Burne Depa rtment of Oral Biology College of Dent stry University of Florida Gainesville USA Department of Restorative Dental Sciences Division of Operative Dentistry College of Dentistry University of Florida Gainesville USA

Alkali production by oral bacteria is believed to have a major impact on oral microbial ecology and to be inibitory to the initiation and progression of dental caries. A substantial body of evidence is beginning to accumulate that indicates the modulation of the alkalinogenic potential of dental biofilms may be a promising strategy for caries control. This brief review highlights recent progress toward understanding molecular genetic and physiologic aspects of important alkali-generating pathways in oral bacteria, and the role of alkali production in the ecology of dental biofilms in health and disease.

关键词： arginine biofilm dental caries microbial ecology urea

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Colon and rectal cancer:An emergent public health problem

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World Journal of Gastroenterology 2024年第7期30卷 644-651页

作者： marina Pinheiro David nascimento Moreira Michele Ghidini LAQV REQUIMTEDepartment of ChemistryFaculty of PharmacyUniversity of Porto4050-313 PortoPortugal Unidade de Saúde Pública Unidade Local de Saúde Barcelos/EsposendeBarcelinhos 4755-069BragaPortugal Medical Oncology Unit Fondazione IRCCS Ca’Granda Ospedale Maggiore PoliclinicoMilan 20122Italy

Colorectal cancer ranks third globally,with a high mortality *** the United States,and different countries in Europe,organized population screenings exist and include people between 50 and 74 years of *** screenings have allowed an early diagnosis and consequently an improvement in health *** and rectal cancer(CRC)is a disease of particular interest due to the high global burden associated with it and the role attributed to prevention and early diagnosis in reducing morbidity and *** study is a review of CRC pathology and includes the most recent scientific evidence regarding this pathology,as well as a diagnosis of the epidemiological situation of ***,the recommendation from a public health perspective will be discussed in detail taking into account the context and the most current recommendations.

关键词： Colon and rectal neoplasia Colon and rectal tumor Mortality Morbidity

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Catalytic combustion of soot over Ru-doped mixed oxides catalysts

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Journal of Rare Earths 2014年第7期32卷 610-620页

作者： L.F.nascimento R.F.martins O.A.Serra Department of Chemistry Faculdade de FilosofiaCiências e Letras de Ribeirao PretoUniversity of Sao PauloAv.Bandeirantes 3900CEP 14040-901 Ribeirao PretoSPBrazil

We employed modified substrates as outer heterogeneous catalysts to reduce the soot originating from the incomplete diesel combustion. Here, we proposed that ceria（CeO2）-based catalysts could lower the temperature at which soot combustion occurred from 610 oC to values included in the operation range of diesel exhausts（270–400 oC）. Here, we used the sol-gel method to synthesize catalysts based on mixed oxides（ZnO：CeO2） deposited on cordierite substrates, and modified by ruthenium nanoparticles. The presence of ZnO in these mixed oxides produced defects associated with oxygen vacancies, improving thermal stability, redox potential, sulfur resistance, and oxygen storage. We evaluated the morphological and structural properties of the material by X-ray diffraction（XRD）, Brumauer-emmett-teller method（BET）, temperature programmed reduction（H2-TPR）, scanning electron microscopy（SEM）, and transmission electron microscopy（TEM）. We investigated how the addition of Ru（0.5 wt.%） affected the catalytic activity of ZnO：CeO2 in terms of soot combustion. Thermogravimetric analysis（TG/DTA） revealed that presence of the catalyst decreased the soot combustion temperature by 250 oC, indicating that the oxygen species arose at low temperatures, which was the main reason for the high reactivity of the oxidation reactions. Comparative analysis of soot emission by diffuse reflectance spectroscopy（DRS） showed that the catalyst containing Ru on the mixed oxide-impregnated cordierite samples efficiently oxidized soot in a diesel stationary motor： soot emission decreased 80%.

关键词： soot combustion ceria mixed oxides ruthenium nanoparticles rare earths

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A High-Order Localized Artificial Diffusivity Scheme for Discontinuity Capturing on 1D Drift-Flux Models for Gas-Liquid Flows

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Advances in Applied Mathematics and Mechanics 2024年第1期16卷 47-74页

作者： Adyllyson H.nascimento Eugenio S.Rosa Department of Energy School of Mechanical EngineeringUniversity of CampinasCampinasBrazil

A computational code is developed for the numerical solution of onedimensional transient gas-liquid flows using drift-flux models,in isothermal and also with phase change *** these two-phase models,classical upwind schemes such as Roe-and Godunov-type schemes are generally difficult to derive and expensive to use,since there are no treatable analytic expressions for the Jacobian matrix,eigenvalues and eigenvectors of the system of *** the other hand,the highorder compact finite difference scheme becomes an attractive alternative on these occasions,as it does not make use of any wave propagation information from the system of *** present paper extends the localized artificial diffusivity method for high-order compact finite difference schemes to solve two-phase flows with *** numerical method has simple formulation,straightforward implementation,low computational cost and,most importantly,*** numerical methodology proposed is validated by solving several numerical examples given in the *** simulations are sixth-order accurate and it is shown that the proposed numerical method provides accurate approximations of shock waves and contact *** is an essential property for simulations of realistic mass transport problems relevant to operations in the petroleum industry。

关键词： Compressible two-phase flows drift-flux model localized artificial diffusivity highorder numerical methods

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Catalytic combustion of soot over ceria-zinc mixed oxides catalysts supported onto cordierite

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Journal of Environmental Sciences 2014年第3期26卷 694-701页

作者： Leandro Fontanetti nascimento Renata Figueredo martins Rodrigo Ferreira Silva Osvaldo Antonio Serra Department of Chemistry FFCLRP University of Sao Paulo

Modified substrates as outer heterogeneous catalysts was employed to reduce the soot generated from incomplete combustion of diesel or diesel/biodiesel blends, a process that harms the environment and public health. The unique storage properties of ceria （CeO2） makes it one of the most efficient catalysts available to date. Here, we proposed that ceria-based catalysts can lower the temperature at which soot combustion occurs; more specifically, from 610℃ to values included in the diesel exhausts operation range （300-450℃）. The sol-gel method was used to synthesize mixed oxide-based catalysts （CeO2：ZnO）; the resulting catalysts were deposited onto cordierite substrates. In addition, the morphological and structural properties of the material were evaluated by XRD, BET, TPR-H2, and SEM. Thermogravimetric （TG/DTA） analysis revealed that the presence of the catalyst decreased the soot combustion temperature by 200℃ on average, indicating that the oxygen species arise at low temperatures in this situation, promoting highly reactive oxidation reactions. Comparative analysis of soot emission by diffuse reflectance spectroscopy （DRS） showed that catalyst-impregnated cordierite samples efficiently oxidized soot in a diesel/biodiesel stationary motor： soot emission decreased by more than 70%.

关键词： soot oxidation mixed oxides ceria

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