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International Journal of Ophthalmology(English edition) 2020年第9期13卷 1368-1373页

作者： josé-maría sánchez-González Concepción De-Hita-Cantalejo maría Carmen sánchez-González Department of Physics of Condensed Matter Optics AreaUniversity of SevilleSeville 41012Spain

AIM:To study the effect of uncrosslinked and crosslinked hyaluronic acid combined with other artificial tear components in patients with dry eye caused by moderate meibomian gland ***:Prospective,single-blind,contralateral eye *** eyes(25 patients)were *** selection for each tear type was random,and the eye drop formulations,0.4%uncrosslinked hyaluronic acid and 0.2%galactoxyloglucan(tear A)and 0.15%crosslinked hyaluronic acid,crocin,and liposomes(tear B)were *** determined dosing schedule was three times a day for six weeks,and the study participants underwent a clinical examination before and 45 d after lubricant *** schirmer test,tear breakup time(TBUT)test,and Ocular surface Disease Index(OsDI)questionnaire were applied before and after instillation period with both types of artificial ***:On the schirmer test,a significant improvement was obtained with both tear A(Pst,a significant improvement was obtained with tear A(PsDI score significantly decreased after instillation period with both artificial tear types(PsION:Uncrosslinked hyaluronic acid combined with other components,such as tamarind seed polysaccharide,and crosslinked hyaluronic acid combined with liposomes and crocin are effective for management symptoms of dry eye disease.

关键词： liposome crosslinked hyaluronic acid meibomian gland dysfunction contact lens dry eye disease

Bayés syndrome and acute cardioembolic ischemic stroke

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World Journal of Clinical Cases 2017年第3期5卷 93-101页

作者： Adrià Arboix Lucía martí sebastien Dorison maría josé sánchez Division of Cerebrovascular Universitat de Barcelona Department of Neurology Hospita Universitari del Sagrat Cor Medicine school Universidad de los Andes 111711 Bogotá Medical Library Hospital Universitari Sagrat Cor

Bayés syndrome is an under-recognized clinical condition characterized by advanced interatrial ***és syndrome is a subclinical disease that manifests electrocardiographically as a prolonged P wave duration>120 ms with biphasic morphology±in the inferior *** clinical relevance of Bayés syndrome lies in the fact that is a clear arrhythmological syndrome and has a strong association with supraventricular arrhythmias,particularly atypical atrial flutter and atrial ***,Bayés syndrome has been recently identified as a novel risk factor for non-lacunar cardioembolic ischemic stroke and vascular *** interatrial block can be a risk for embolic stroke due to its known sequelae of left atrial dilation,left atrial electromechanical dysfunction or atrial tachyarrhythmia(paroxysmal or persistent atrial fibrillation),conditions predisposing to ***és syndrome may be responsible for some of the unexplained ischemic strokes and shall be considered and investigated as a possible cause for cryptogenetic *** summary,Bayés syndrome is a poorly recognized cardiac rhythm disorder with important cardiologic and neurologic implications.

关键词： Bayés syndrome Cardioembolic stroke Electrophysiological processes Cardiovascular risk factors Heart conduction system

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西班牙梅里达古罗马狄安娜神庙区域更新设计

建筑遗产 2024年第1期 107-117页

作者： [西]何塞·马利亚·桑切斯·加西亚檀烨(译) 马德里理工大学马德里28040 不详

古罗马狄安娜神庙及其周边考古遗址是西班牙梅里达市最重要的区域之一,随着城市的发展,其周边场地被围墙围合,丧失了城市公共性。文章首先指出建筑师在古罗马狄安娜神庙区域更新项目中的首要目标,是重新利用古罗马时期遗留的广场空间,... 详细信息

古罗马狄安娜神庙及其周边考古遗址是西班牙梅里达市最重要的区域之一,随着城市的发展,其周边场地被围墙围合,丧失了城市公共性。文章首先指出建筑师在古罗马狄安娜神庙区域更新项目中的首要目标,是重新利用古罗马时期遗留的广场空间,在延续历史痕迹的同时重建城市公共空间;文章进一步从场地、几何形态和材料三方面详细分析了具体的设计策略,包括重整场地秩序,根据遗址和周边住宅情况新建“围廊建筑”,通过对“围廊建筑”层高、材料和细部构造的精心设计,与神庙对话,最终形成以神庙为中心的复合广场空间;新建建筑充分尊重历史遗产,满足当代功能,为城市创造了充满活力、灵活可变的公共空间。

关键词：古罗马狄安娜神庙围廊建筑场地几何材料更新考古遗产

Experimental implementation of phase triplicator gratings in a spatial light modulator

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Chinese Optics Letters 2024年第2期22卷 64-69页

作者：高尚 maría del mar sánchez-López Ignacio Moreno Instituto de Bioingeniería Universidad Miguel HernándezElche 03202Spain Departamento de Física Aplicada Universidad Miguel HernándezElche 03202Spain Departamento de Ciencia de Materiales Óptica y Tec.Electr´onicaUniversidad Miguel HernándezElche 03202Spain

In this work,we compare different methods for implementing a triplicator,a phase grating that generates three equiintense diffraction *** design with optimal efficiency features a continuous phase profile,which cannot be easily reproduced,and is typically affected by *** compare its performance with binary and sinusoidal phase *** also analyze the effect of quantizing the phase ***,a random approach is adopted to eliminate the additional harmonic *** all cases,a liquid-crystal-on-silicon spatial light modulator is employed to experimentally verify and compare the different approaches.

关键词： diffraction gratings phase modulation triplicator spatial light modulators

Cost Optimisation for Minimizing the Visual Impact of Ornamental stone Quarrying. A Case study in Murcia Region

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Journal of Geoscience and Environment Protection 2018年第2期6卷 74-88页

作者： josé Molina-Ruiz maría josé martínez-sánchez Carmen Pérez-sirvent mari Luz García-Lorenzo maría Luz Tudela-serrano Department of Geography Faculty of Geography University of Murcia Campus de la Merced Murcia Spain Department of Agricultural Chemistry Geology and Pedology Faculty of Chemistry University of Murcia Campus de Espinardo Murcia Spain Department of Mineralogy and Petrology Faculty of Geology University Complutense of Madrid Madrid Spain

Quarrying of ornamental stone has adverse effects that are both visual and environmental. This paper aims to develop a methodology for minimising the costs associated with reducing the visual impact of ornamental stone quarrying. This study uses digital topographical maps of the study zone and a GPs and GIs application to calculate the extent of the area affected by quarrying activities for each altitude designated in the work plan and to calculate the extent of the potential visual impact. The results obtained applying the proposed methodology for the selected area suggested that the potential visual impact is minimal for an altitude of 520 metres, this being the optimal point for the observer. When altitude increases, the potential visual impact increases and the optimal point for the observer diminishes until the highest impact altitude (740 m) is readied. The optimal point that the exploitation should reach is that at which the values of the diagram generated by the (%) area of potential visual impact and area of exploitation (%) intersect. The methodology allows the optimal altitude to be determined for mining exploitations and helps assess the viability of a given exploitation from an environmental point of view.

关键词： Restoration Costs Ornamental stone Visual Impact Limestone Quarrying

Does enhanced recovery after surgery programs improve clinical outcomes in liver cancer surgery?

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World Journal of Gastrointestinal Oncology 2024年第2期16卷 255-258页

作者： Belinda sánchez-Pérez joséM Ramia Department of General Digestive and Transplantation SurgeryUniversity Regional HospitalMálaga 29010MálagaSpain Department of surgery Hospital General Universitario Dr.BalmisAlicante 03010Spain

Enhanced recovery after surgery(ERAs)programs have been widely applied in liver surgery since the publication of the first ERAs guidelines in 2016 and the new recommendations in *** surgery is usually performed in oncological patients(liver metastasis,hepatocellular carcinoma,cholangiocarcinoma,etc.),but the real impact of liver surgery ERAs programs in oncological outcomes is not clearly *** advantages of ERAs programs are:ERAs decreases postoperative complication rates and has been demonstrated a clear relationship between complications and oncological outcomes;a better and faster posto-perative recovery should let oncologic teams begin chemotherapeutic regimens on time;prehabilitation and nutrition actions before surgery should also improve the performance status of the patients receiving ***,ERAs could be another way to improve our oncological *** will discuss the literature about liver surgery ERAs focusing on its oncological implications and future investigations projects.

关键词： Enhanced recovery after surgery programs Liver surgery Key components Long-term oncological outcomes Enhanced recovery after surgery compliance

Assessment of the Acoustic Impact of Wind Farm Projects: Methodology and Case

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Journal of Geoscience and Environment Protection 2018年第1期6卷 99-110页

作者： jose Molina-Ruiz mari Luz García-Lorenzo maría josé martínez-sánchez Diego Gallego Department of Geography Faculty of Geography University of Murcia Murcia Spain Department of Mineralogy and Petrology Faculty of Geology University Complutense of Madrid Madrid Spain Department of Agricultural Chemistry Geology and Pedology Faculty of Chemistry University of Murcia Murcia Spain Diego Gallego Cambronero Departamento Ecologia Faculty of Sciences University of Alicante Alicante Spain

Wind energy is a clean renewable and its benefits are considered greater than the disadvantages. However, even though wind farms represent environmentally friendly projects, they frequently generate public resistance. Wind turbines are socially controversial because of their visual and acoustic impacts. The aim of this work was to design a methodology for the preliminary evaluation of potential acoustic impact of wind farms. Three steps have been proposed: identification, characterization and assessment of the acoustic impact during the construction, operation and decommissioning phase. Obtained results in the studied area suggested that at a maximum power, at 500 meters of wind turbines, noise level is lower than the reference level established in the legislation. In summary, proposed methodology could help to determine and to evaluate the best location for new wind farm projects. Proposed methodology could help to determine and to evaluate the best location for new wind farm projects. Moreover, this method could be used as a consulting tool for public organizations and private institutions, being quick, concise and clear. Obtained results for the studied wind farm project suggested that almost all the area showed noise levels lower than established background noise level.

关键词： Wind Turbine Environmental Impact Assessment Acoustic Impact Wind Farm

Tracking the change in spanish greenhouse gas emissions through an LMDI decomposition model:A global and sectoral approach

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Journal of Environmental sciences 2024年第5期139卷 114-122页

作者： Paula Fernández González maría josé Presno Manuel Landajo Department of Applied Economics University of OviedoAuda del Cristos/n 33011 OviedoSpain

The reduction of GHG emissions to reverse the greenhouse effect is one of the main challenges in this *** this paper we pursue two ***,we analyze the evolution of GHG emissions in spain in 2008–2018,at both the global and sectoral levels,with the variation in emissions decomposed into a set of determining ***,we propose several actions specifically oriented to more tightly controlling the level of *** results showed a remarkable reduction(18.44%)in GHG emissions,mainly due to the intensity effect,but also to the production-per-capita *** detected somewhat different patterns among the various sectors *** the intensity effect was the most influential one in the agricultural,transport,and others sectors,the production-per-capita effect was predominant in the case of *** carbonization effect was revealed as crucial in the commerce *** above findings highlight the importance of the energy efficiency measures taken in recent years in the spanish economy,also pointing to the need to deepen those strategies and to propose new measures that entail greater efficiency in *** efforts in areas like innovation,R&D,diffusion of more eco-friendly technologies,and a greater use of greener energies all prove to be essential reduction actions to fight the greenhouse effect.

关键词： LMDI Decomposition spain GHG emissions

Cortical laminar necrosis related to migrainous cerebral infarction

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World Journal of Clinical Cases 2013年第8期1卷 256-259页

作者： Adrià Arboix sebastià González-Peris Elisenda Grivé maría-josé sánchez Emili Comes Cerebrovascular Division Department of NeurologyHospital Universitari del Sagrat Cor.Universitat de BarcelonaE-08029 BarcelonaSpain Department of Neuroradiology Hospital Universitari Sagrat Cor.E-08029 BarcelonaSpain Medical Library Hospital Universitari Sagrat Cor.E-08029 BarcelonaSpain

We present a 29-year-old woman with a long history of attacks of migraine with and without visual *** was a heavy smoker(20 cigarettes/d) and was currently taking oral contraceptives. During a typical migraine attack with aura, she developed dysarthria,left brachial hemiparesis and hemihypoesthesia and brief and autolimited left clonic facial movements. Four hours after onset, vascular headache and focal sensorimotor neurological deficit were the only persisting symptoms and, on seventh day, she was completely recovered. Brain magnetic resonance imaging on day 20 after onset showed a subacute ischemic lesion in the right temporo-parietal cortex compatible with cortical laminar necrosis(CLN). Extensive neurological work-up done to rule out other known causes of cerebral infarct with CLN was unrevealing. Only ten of 3.808 consecutive stroke patients included in our stroke registry over a 19-year period fulfilled the strictly defined International Headache society criteria for migrainous stroke. The present case is the unique one in our stroke registry that presents CLN related to migrainous cerebral infarction. Migrainous infarction can result in CLN.

关键词： Cortical laminar necrosis Migrainous stroke Migraine Cerebrovascular diseases stroke

The immune system:uncharted pathways between senses and the brain

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Neural Regeneration Research 2024年第6期19卷 1173-1174页

作者： Noelia Casares mar Cuadrado-Tejedor Ana García-Osta Juan joséLasarte Immunology and Immunotherapy Program Centre for Applied Medical Research(CIMA)University of NavarraIDISNAPamplonaSpain Division of Gene Therapy for Neurological Disorders Centre for Applied Medical Research(CIMA)University of NavarraIDISNAPamplonaSpain Pathology Anatomy and Physiology DepartmentSchool of MedicineUniversity of NavarraIDISNAPamplonaSpain

Humans and animals use the classic five senses-sight,hearing,touch,smell,and taste-to detect and monitor their environment,with the sense of position and movement often referred to as the sixth *** perception of external signals through the senses is essential to an organism's survival,transmitting signals to the central nervous system(CNs)and prompting physiological changes in other biological *** addition to the direct effects of sense-induced mediators in the brain.

关键词： prompt system transmitting