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Turbo-taxonomy to assemble a megadiverse lichen genus:seventy new species of Cora(Basidiomycota:Agaricales:Hygrophoraceae),honouring David Leslie Hawksworth’s seventieth birthday

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Fungal Diversity 2017年第3期84卷 139-207页

作者： Robert Lücking Manuela Dal Forno Bibiana Moncada Luis Fernando Coca Leidy Yasmín Vargas-Mendoza André Aptroot laura Juliana Arias Betty Besal Frank Bungartz Diego Mauricio Cabrera-Amaya marcela E.S.Cáceres José Luis Chaves Sionara Eliasaro martha Cecilia Gutiérrez Jesús E.Hernández marin maría de los Ángeles Herrera-Campos maría E.Holgado-Rojas Harald Jonitz martin Kukwa Fabiane Lucheta Santiago Madriñán marcelo Pinto marcelli Suzana maria de Azevedo martins Joel A.Mercado-Díaz Jorge Alberto Molina Eduardo A.Morales Peter R.Nelson Freddy Nugra Francisco Ortega Telma Paredes Ayda Lucía Patiño Rouchi Nadine Peláez-Pulido rosa Emilia Pérez Pérez Gary B.Perlmutter Eimy Rivas-Plata Javier Robayo Camilo Rodríguez Diego Fernando Simijaca Edier Soto-Medina Adriano Afonso Spielmann Alejandra Suárez-Corredor Jean-marc Torres Carlos Alberto Vargas Alba Yánez-Ayabaca Gothamie Weerakoon Karina Wilk marcela Celis Pacheco Mauricio Diazgranados Grischa Brokamp Thomas Borsch Patrick M.Gillevet Masoumeh Sikaroodi James D.Lawrey Botanical Garden and Botanical Museum Berlin KöniginLuise-Straße 6-814195 BerlinGermany Science Education The Field Museum1400 South Lake ShoreChicagoIL 60605USA Department of Botany Smithsonian InstitutionNational Museum of Natural History10th St Constitution Ave NWWashingtonDC 20560USA Department of Environmental Science and Policy George Mason UniversityFairfaxVA 22030-4444USA Licenciatura en Biologı´a Universidad Distrital Francisco Jose´de CaldasCra.4 No.26D-54Torre de LaboratoriosHerbarioBogota´D.C.Colombia Herbario Universidad de Caldas(FAUC) Edificio BicentenarioCalle 65No.26-10ManizalesA.A.275CaldasColombia ABL Herbarium G.v.d.Veenstraat 1073762 XK SoestThe Netherlands Biologı´a Universidad del Quindı´oCarrera 15 Calle 12 NorteArmeniaQuindı´oColombia 120 Chavis Avenue LexingtonVA 24450USA Charles Darwin Foundation Puerto AyoraSanta Cruz IslandGala´pagosEcuador Schedestraße 8 53113 BonnGermany Jardı´n Bota´nico de Bogota´Jose´Celestino Mutis Avenida Calle 63 No.68-95Bogota´D.C.Colombia Departamento de Biocieˆncias Universidade Federal de SergipeAvenida Vereador Olı´mpio Grandes/n.ItabaianaCEP:49.500-000 SergipeBrazil Laboratorio de Hongos Instituto Nacional de Biodiversidad(INBio)Apdo.22-3100Santo Domingo de HerediaCosta Rica Departamento de Botaˆnica Universidade Federal do Parana´Campus Polite´cnicoSetor de Cieˆncias Biolo´gicasAv.Cel.Francisco H.dos Santoss/nJardim das Ame´ricas81531-980 CuritibaPRBrazil Ingenierı´a Ambiental Universidad Distrital Francisco Jose´de CaldasCarrera 5 Este No.15-82Av.CircumvalarBogota´D.C.Colombia Instituto Experimental Jardı´n Bota´nico Dr.Tobı´as Lasser Centro de Investigacio´n y DesarrolloUniversidad Central de VenezuelaAve.Salvador AllendeJardı´n Bota´nico de CaracasApartado#2156Caracas 1010-AVenezuela Departamento de Bota´nica Instituto de Biologı´aUniversidad Nacional Auto´noma de Me´xicoApartado Postal 70-36704510 Ciudad De Me´xicoMexico Facultad de Ciencias Escuela Profesional de Biologı´aUniv

Following a large-scale phylogenetic study of the lichenized genus Cora(Basidiomycota:Agaricales:Hygrophoraceae),we formally describe 70 new species,honouring the seventieth birthday of David Leslie Hawksworth,one of the preeminent figures in mycology and lichenology in the past 50 *** on an updated phylogeny using the ITS fungal barcoding locus,we now recognize 189 taxa in a genus that until recently was considered to represent a single species;including this contribution,92 of these are formally recognized,including five taxa based on historical names or collections that have not been *** of Cora can be recognized by a combination of morphological(size,colour,lobe configuration,surface hairs,hymenophore size and shape),anatomical(thallus thickness,cortex structure,photobiont type,hyphal papillae),and ecogeographical features(substrate,habitat,distribution),and a keytable allowing the identification of all accepted taxa is *** new species are:Cora accipiter Moncada,Madrin˜a´n&Lücking ***.,*** Moncada,Soto-Medina&Lücking ***.,*** Moncada,Dal Forno&Lücking ***.,*** Dal Forno,Chaves&Lücking ***.,*** Moncada,***ı´guez&Lücking ***.,*** Lücking,Moncada&*** ***.,*** Moncada,Ya´nez-Ayabaca&Lücking ***.,*** Moncada,Patin˜o&Lücking ***.,*** Lücking,***&Dal Forno ***.,*** Holgado,Rivas Plata&Perlmutter ***.,*** Dal Forno,Eliasaro&Spielmann ***.,*** Nugra,Dal Forno&Lücking ***.,*** Lücking,martins&Lucheta ***.,*** Moncada,R.-***´rez&Lücking ***.,*** Moncada,***.&Lücking ***.,*** Moncada,CabreraAmaya&Lücking ***.,*** Moncada,R.-***´rez&***.,*** Lücking,***&Dal Forno ***.,*** Moncada,***´rez-Corredor&Lücking ***.,*** Moncada,***&Lücking ***.,***

关键词： Bolivia Citizen science Chile Mexico Puerto Rico Sri Lanka

Efficacy of Alzer<sup>®</sup>and Diamel, Nutritional Supplements, in the Prevention of Severe Diabetic Macular Edema

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Open Journal of Ophthalmology 2020年第4期10卷 307-322页

作者： Juana Elvira Maciques Rodríguez maria Emoé Pérez Muñoz Eduardo Cabrera Rode laura rosa Redondo Piño Raísa Beltrán Sainz Teresa González Calero Manuel Licea Puig Juan Lence Anta rosaralis Paneca Santiesteban Yordanka marrero Álvarez Eduardo Sanz Navares Instituto Nacional de Endocrinología Havana Cuba Hospital Universitario Salvador Allende Havana Cuba Instituto Nacional de Oncologia Havana Cuba Catalysis SL. Madrid Spain

Introduction: Macular edema is the main cause of low vision in diabetic patients. Laser photocoagulation continues to be the treatment of choice in conjunction with the use of steroids and anti-angiogenics, but these treatments include possible ocular complications. The nutritional supplement Alzer (whose primary active ingredient is Ginkgo biloba, a powerful antioxidant that acts on vascular factors and oxidative damage, which are two of the mechanisms implicated in the pathogenesis of diabetic macular edema), which has been used on other non-diabetic macular conditions, along with the Diamel nutritional supplement has been shown to be effective on glycemic control and could represent a treatment alternative for mild to moderate macular edema by reducing the thickness of the macular retina and preventing the progression of other more advanced clinical presentations that are harder to treat. Objective: Identify the effect of Alzer along with Diamel in reduction of the thickness of the macular retina among patients with mild to moderate diabetic macular edema. Materials and Methods: A phase II double-blind clinical trial was conducted in 64 patients with non-severe diabetic macular edema over the course of non-proliferative diabetic retinopathy, who attended the ophthalmology service of the Institute of Endocrinology of Havana from January 2016 to December 2016. The treatment was randomly assigned to two groups: one received Alzer plus Diamel (n

关键词： Alzer Diamel Ginkgo Biloba Macular Edema Macular Thickness Nutritional Supplement

Application of antigenic biomarkers for Mycobacterium tuberculosis

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2020年第11期21卷 856-870页

作者： Elba RODRIGUEZ-HERNANDEZ laura Itzel QUINTAS-GRANADOS Susana FLORES-VILLALVA Jorge Germinal CANTO-ALARCON Feliciano MILIAN-SUAZO Instituto Nacional de Investigaciones Forestales Agricolas y Pecuarias(INIFAP)Centro Nacional de Investigacion Disciplinaria en Fisiologia y Mejoramiento AnimalKm.1 Carretera a ColonAjuchitlan Colon76280ColonQueretaroMexico Universidad Mexiquense del Bicentenario Unidad de Estudios Superiores de TultitlanAvenida Ex-Hacienda de Portales s/nVilla EsmeraldaTultitlan Estado de Mexico54910TultitlanMexico Universidad Autonoma de Queretaro Facultadde Ciencias NaturalesAvenida de las Ciencias s/nJuriquillaDelegacion Santa Rosa Jauregui76230QueretaroMexico

The study and characterization of biomolecules involved in the interaction between mycobacteria and their hosts are crucial to determine their roles in the invasion process and provide basic knowledge about the biology and pathogenesis of *** new biomarkers for diagnosis and immunotherapy have emerged *** is an ancient pathogen that has developed complex strategies for its persistence in the host and environment,likely based on the complexity of the network of interactions between the molecules involved in *** biomarkers have received recent attention in the process of developing rapid and reliable detection techniques for *** the most widely investigated antigens are CFP-10(10-kDa culture filtrate protein),ESAT-6(6-kD a early secretory antigenic target),Ag85 A,Ag85 B,CFP-7,and *** of these antigens have been proposed as biomarkers to assess the key elements of the response to infection of both the pathogen and *** design of novel and accurate diagnostic methods is essential for the control of tuberculosis ***,the diagnostic methods are based on the identification of molecules in the humoral response in infected ***,these tests depend on the capacity of the host to develop an immune response,which usually is *** the last 20 years,special attention has been given to the design of multiantigenic diagnostic methods to improve the levels of sensitivity and *** this review,we summarize the state of the art in the study and use of mycobacterium biomolecules with the potential to support novel tuberculosis control strategies.

关键词： Mycobacterium tuberculosis Recombinant antigen Diagnostics Biomarker

Comparative study of breast cancer in Mexican and Mexican-American women

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Health 2010年第9期2卷 1040-1048页

作者： maria Elena martinez Luis Enrique Gutierrez-Millan Melissa Bondy Adrian Daneri-Navarro maria Mercedes Meza-Montenegro Ivan Anduro-Corona Ma Isabel Aramburo-Rubio Luz maria Adriana Balderas-Pena Jose Adelfo Barragan-Ruiz Abenaa Brewster Graciela Caire-Juvera Juan Manuel Castro-Cervantes mario Alberto Chavez Zamudio Giovanna Cruz Alicia Del Toro-Arreola mary EEdgerton maria rosa Flores-marquez Ramon Antonio Franco-Topete Helga Garcia Susan Andrea Gutierrez-Rubio Karin Hahn Luz margarita Jimenez-Perez Ian KKomenaka Zoila Areli Lopez Bujanda Dihui Lu Gilberto Morgan-Villela James LMurray Jesse NNodora Antonio Oceguera-Villanueva Miguel Angel Ortiz martinez laura Perez Michel Antonio Quintero-Ramos Aysegul Sahin Jeong Yun Shim Maureen Stewart Gonzalo Vazquez-Camacho Betsy Wertheim Rachel Zenuk Patricia Thompson Arizona Cancer Center and Mel and Enid Zuckerman College of Public Health University of ArizonaTucsonUSA Departamento de Investigaciones Cientificas y Tecnologicas Universidad de SonoraHermosilloMexico University of Texas M.D.Anderson Cancer Center HoustonUSA Departamento de Fisiologia Centro Universitario de Ciencias de la SaludUniversidad de GuadalajaraGuadalajaraMexico Instituto Tecnologico de Sonora Ciudad ObregónMexico Instituto Mexicano del Seguro Social HermosilloMexico Instituto Mexicano del Seguro Social CMNOGuadalajaraJalisco Centro de Investigacion en Alimentacion y Desarrollo HermosilloMexico Instituto Mexicano del Seguro Social Ciudad ObregonMexico OPD Hospital Civil de Guadalajara GuadalajaraMexico Departamento de Salud Publica Centro Universitario de Ciencias de la SaludUniversidad de GuadalajaraGuadalajaraMexico maricopa Medical Center Department of SurgeryPhoenixUSA University of North Carolina Lineberger Cancer CenterChapel HillUSA Arizona Cancer Center and Department of Family and Community Medicine University of ArizonaTucsonUSA Instituto Jalisciense de Cancerologia GuadalajaraMexico

Breast cancer is the number one cause of can- cer deaths among Hispanic women in the United States, and in Mexico, it recently became the primary cause of cancer deaths. This malign- nancy represents a poorly understood and un- derstudied disease in Hispanic women. The ELLA Binational Breast Cancer Study was es- tablished in 2006 as a multi-center study to as- sess patterns of breast tumor markers, clinical characteristics, and their risk factors in women of Mexican descent. We describe the design and implementation of the ELLA Study and provide a risk factor comparison between women in the U.S. and those in Mexico based on a sample of 765 patients (364 in the U.S. and 401 in Mexico). Compared to women in Mexico, U.S. women had significantly (p < 0.05) lower parity (3.2 vs. 3.9 mean live births) and breastfeeding rates (57.5% vs. 80.5%), higher use of oral contraceptives (60.7% vs. 50.1%) and hormone replacement therapy (23.3% vs. 7.6%), and higher family history of breast cancer (15.7% vs. 9.0%). Re- sults show that differences in breast cancer risk factor patterns exist between Mexico and U.S. women. We provide lessons learned from the conduct of our study. Binational studies are an important step in understanding disease pat- terns and etiology for women in both countries.

关键词： Binational Study Breast Cancer Hispanics Mexico United States