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Software improvement for evaluation of laryngopharyngeal pH testing(Restech)——a comparison between Data View 3 and 4

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World Journal of Gastrointestinal Surgery 2020年第5期12卷 236-246页

作者： dolores Thea Müller Elena Schulte Benjamin Babic Laura Knepper Claudia Fuchs Wolfgang Schroder Christiane J Bruns Jessica M Leers Hans Friedrich Fuchs Department of General VisceralCancer and Transplant SurgeryUniversity of CologneKoln 50937Germany

BACKGROUND When gastroesophageal reflux contents reach above the upper esophageal sphincter,patients may,in addition to typical reflux symptoms,present with atypical,extraesophageal symptoms related to laryngopharyngeal reflux(LPR).Surgical treatment of LPR has shown to lead to 70%symptom improvement,however no gold standard for the diagnosis of LPR *** 2007,the Restech Dx-pH was released as a valid method to measure acid exposure above the upper esophageal ***,a new software update was introduced for analysis of measured pH data and calculation of composite *** effect of the changes applied to the new software version have not yet been *** To compare results generated by Data View 3 to the most recently released Data View *** All patients with gastroesophageal reflux disease symptoms were seen in a specialized surgical outpatient clinic for gastrointestinal function *** chart review was performed of all patients presenting with suspected gastroesophageal reflux disease and extraesophageal reflux symptoms,who underwent laryngopharyngeal pH monitoring using the Restech Dx-pH system(Respiratory Technology Corp.,Houston,TX,United States)and simultaneous esophageal pH *** View 3 and Data View 4 were used to evaluate Restech studies *** entries such as mealtimes,supine and upright periods,and symptoms were entered manually to ensure accuracy and precise conversion of data between both software *** t test was performed for statistical analysis of *** A total of 174 patients(63.8%female)met inclusion criteria,all suffering from extraesophageal reflux symptoms as well as typical gastroesophageal reflux disease *** RYAN score upright was 48.77 in Data View 3 compared to 22.17 in Data View 4,showing a significant difference(~aP=0.0001).Similar results were shown for supine period(mean RYAN Score Data View 35.29 vs 1.42 in Data View 4,~cP=0.0001).For upright pe

关键词： Gastroesophageal reflux disease Laryngopharyngeal reflux disease Esophageal pH testing Oropharyngeal pH testing Restech Dx pH DeMeester score RYAN Score

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Pathways of Phosphorus Absorption and Early Signaling between the Mycorrhizal Fungi and Plants

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Phyton-International Journal of Experimental Botany 2021年第5期90卷 1321-1338页

作者： Griselda Madrid-Delgado marcos Orozco-Miranda mario Cruz-Osorio Ofelia Adriana Hernández-Rodríguez Raúl Rodríguez-Heredia Melchor Roa-Huerta Graciela dolores Avila-Quezada Facultad de Ciencias Agrotecnológicas Universidad Autónoma de Chihuahua(UACH)Chihuahua31000México Innovak Global Chihuahua31375México

This review highlights the key role that mycorrhizal fungi play in making phosphorus(Pi)more available to plants,including pathways of phosphorus absorption,phosphate transporters and plant-mycorrhizal fungus symbiosis,especially in conditions where the level of inorganic phosphorus(Pi)in the soil is *** fungi colonization involves a series of signaling where the plant root exudates strigolactones,while the mycorrhizal fungi release a mixture of chito-oligosaccharides and liposaccharides,that activate the symbiosis process through gene signaling pathways,and contact between the hyphae and the *** the symbiosis is established,the extraradical mycelium acts as an extension of the roots and increases the absorption of nutrients,particularly phosphorus by the phosphate *** then moves along the hyphae to the plant root/fungus *** transfer of Pi occurs in the apoplectic space;in the case of arbuscular mycorrhizal fungi,Pi is discharged from the arbuscular to the plant’s root symplasm,in the membrane that surrounds the *** is then absorbed through the plant periarbuscular membrane by plant phosphate ***,plants can acquire Pi from soil as a direct absorption *** a result of this review,several genes that codify for high-affinity Pi transporters were *** plants,the main family is Pht1 although it is possible to find others such as Pht2,Pht3,Pho1 and *** in plants,mycorrhizal fungi have genes belonging to the Pht1 *** arbuscular mycorrhizal fungi we found L1PT1,GiPT,MtPT1,MtPT2,MtPT4,HvPT8,ZmPht1,TaPTH1.2,GmosPT and ***1,HcPT2 and BePT have been characterized in ectomycorrhizal *** gene has a different way of expressing *** this review,we present diagrams of the symbiotic relationship between mycorrhizal fungi and the *** knowledge allows us to design solutions to regional problems such as food production in soils with low levels of Pi.

关键词： Interaction,mycorrhiza establishment,symbiosis phosphate uptake

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散货海港泊位分配及装卸设备调度协同优化研究

散货海港泊位分配及装卸设备调度协同优化研究

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作者： dolores G. Perez Orozco 上海交通大学

学位级别：硕士

大宗货物需求的日益增长趋势促使包括散货海港在内的港口提高效率。2015年7月新加坡港的石油吞吐量创了新高并导致了港区的拥堵,中国和澳大利亚的港口由于煤炭进出口需求的增大面临着同样的问题。因此,有必要通过开发数学优化模型以提... 详细信息

大宗货物需求的日益增长趋势促使包括散货海港在内的港口提高效率。2015年7月新加坡港的石油吞吐量创了新高并导致了港区的拥堵,中国和澳大利亚的港口由于煤炭进出口需求的增大面临着同样的问题。因此,有必要通过开发数学优化模型以提高港口作业的效率。本论文研究目的是通过开发泊位分配及装卸设备调度协同优化模型以提高散货海港的作业效率。针对离散泊位布局,本文既考虑船舶在码头的停靠位置(泊位分配),又根据货物的类型做出装卸设备调度的决策,以最小化船舶在港靠泊时间。所构建的数学优化模型考虑了不同装卸设备(如输送带、管道、抓斗起重机和水泥设施)的具体作业效率。基于实际港口的案例研究表明,该模型合理分配了专用泊位、专用装卸设备,显著减少了在港靠泊时间和拥堵。本文同时针对港口可持续性和韧性的概念开展了系统性的文献综述,为港口建设具备可持续性的系统总结了经验和建议。

关键词：散货海港可持续性泊位分配航运物流

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Physiological and Morphological Responses of Susceptible and Resistant Barleys to Bird Cherry-Oat Aphid Feeding

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American Journal of Plant Sciences 2023年第10期14卷 1115-1129页

作者： Rafael Hayashida John Scott Armstrong William Wyatt Hoback dolores Mornhinweg Department of Entomology and Plant Pathology Oklahoma State University Stillwater OK USA United States Department of Agriculture Agricultural Research Service Peanut and Cereal Crops Research Unit Stillwater OK USA

The bird cherry-oat aphid (Rhopalosiphum padi [Linnaeus, 1758]) is considered a key pest of cereal crops worldwide, causing direct damage through sap feeding and by acting as a vector for viral diseases. Managing aphids is challenging because of their biology and potential resistance to insecticides. Developing resistant barley genotypes is a sustainable strategy for managing BCOA. In this study, we assessed responses of susceptible “Morex” and resistant “BCO R001” barley, Hordeum vulgare L. genotypes to different initial BCOA densities (0, 50, 100 or 200 ***-1). Physiological and morphological parameters were measured weekly for four weeks after infestation. Chlorophyll content, photosynthetic rate, plant aerial fresh and dry weight were greater for the resistant cultivar at lower aphid abundances and up to three weeks after infestation. Carbon assimilation curves (A/Ci) of infested “BCO R001” were similar to controls 15 days post infestation, differing from Morex. However, BCOA infestation of 50 ***-1 for two weeks negatively impacted the fitness of both genotypes. Initial resistance by BCO R001 to BCOA infestation can allow growers and natural enemies more time contributing to more effective and sustainable management of BCOA infestations.

关键词： Plant Tolerance Hemiptera Piercing-Sucking Injury Cereal Crops

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Canine Leptospirosis Serology in Southern Mexico City

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Open Journal of Medical Microbiology 2016年第4期6卷 171-180页

作者： Ignacio martínez-Barbabosa Edubiel Arturo Alpizar-Sosa dolores Guadalupe Gavaldón-Rosas Luís Pedro Moles-Cervantes marcia Gutiérrez Cárdenas Rafael García-González Michael Shea Ana maría Fernández-Presas Health Attention Department Human Parasitology Laboratory Universidad Autónoma Metropolitana-Xochimilco México DF México Animal and Agriculture Production Department Universidad Autónoma Metropolitana-Xochimilco México DF México Microbiology and Parasitology Department School of Medicine Universidad Autónoma de México México DF México Education and Communication Department Universidad Autónoma Metropolitana-Xochimilco México DF México

Background: Leptospirosis is an important zooanthroponotic disease spread worldwide which infection is recognized as a re-emergent disease. Leptospirosis is a systemic disease of humans and domestic animals, mainly dogs, cattle and swine, characterized by fever, renal and hepatic insufficiency, pulmonary manifestations and reproductive failure. Objective: To study the seroprevalence of anti-Leptospira antibodies in an urban canine population. Materials and Methods: The study was performed in march 2014 in stray dogs that had been captured in the districts of Coyoacan, Iztapalapa, Iztacalco and Benito Juarez in Mexico City;117 dogs were analyzed, from each of which 5 ml of blood were obtained. Serology was performed using a MAT test (Microscopic Agglutination Test), finding that the antigens corresponded to 13 serotypes of Leptospirainterrogans. Three age groups were formed: Group 1) younger than a year (n = 28), Group 2) 1 to 6 years (n = 75), and Group 3) older than 6 years (n = 14). Results: Of the analyzed sera, 28.2% were seropositive to one or more Leptospira serotypes, 74% of the positive seracoagglutinated with two or more serotypes. The most frequent serotypes were: Canicola, Icterohaemorrhagiae and Portland-vere. Serotypes Canicola, Pyrogenes, and Bratislava resulted statistically significant (p 0.001). The presence of anti-Leptospira antibodies in the blood of animals of 1 to 6 years resulted with a p 0.001. The sera from Iztapalapa reacted to nine serotypes. Conclusion: The 28.2% of seropositivity indicates Leptospira transmission in the canine population that was studied could exhibit a potential public health risk.

关键词： Leptospira Leptospirosis Canicola Icterohaemorrhagiae Dogs

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黄连素及其与BCNU联合应用治疗恶性脑肿瘤的实验研究

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中国神经精神疾病杂志 1993年第2期19卷 86-89页

作者：张荣勋 markL.Posenblum dolores V.Dougherty 河北医学院第二附属医院神经外科 050000 美国旧金山加里福尼亚大学医学院神经外科脑肿瘤研究中心

本文对黄连素的抗脑肿瘤作用,以及与1,3-bis(2-chloroethyl)-l-nitrosourea(BC-NU)联合应用进行了实验研究。用集落生成率测定(CFE)对6个人类脑胶质瘤细胞株和大白鼠9L脑肿瘤细胞(胶质肉瘤)进行了离体研究。用姐妹染色体交换法(SCE),对9... 详细信息

本文对黄连素的抗脑肿瘤作用,以及与1,3-bis(2-chloroethyl)-l-nitrosourea(BC-NU)联合应用进行了实验研究。用集落生成率测定(CFE)对6个人类脑胶质瘤细胞株和大白鼠9L脑肿瘤细胞(胶质肉瘤)进行了离体研究。用姐妹染色体交换法(SCE),对9L脑肿瘤细胞进行了评价。同时,在活体实验中用集落生成率测定对脑内固体9L脑肿瘤的治疗进行了分析。在BCNU的浓度为23μm单独使用时,对6个人类脑胶质瘤细胞株可获得平均为43％的细胞杀灭作用(0.24Log Kill)。而在黄连素与23μmBCNV联合应用治疗中,则可见到平均为97％的细胞杀灭相加作用(1.55Log Kill)。在采用150μg/ml黄连素离体治疗中,9L细胞姐妹染色体相对数的增高超过底数的2.7倍。在活体实验中,黄连素与BCNU联合应用也显示出细胞毒性相加作用。

关键词：黄连素 BCNU 脑肿瘤联合用药

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The Epidemio-Clinic Profile of Clandestine Abortion at Saint Joseph Hospital (Kinshasa)

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Open Journal of Obstetrics and Gynecology 2018年第12期8卷 1176-1184页

作者： Leon Mubikayi Aristide Yamba Yannick Mubikayi Elisee Kuedimutshima dolores Nembunzu School of Medicine Kasayi University Kananga Democratic Republic of the Congo Nurse School of Kananga Kananga Democratic Republic of the Congo Saint Joseph Hospital Kinshasa Democratic Republic of the Congo

Objective: To identify the epidemiologic profile of the woman having practiced the clandestine abortion, to determine the frequency and the complications of the clandestine abortion and to evaluate the prognosis of the clandestine abortion in our area. Method: The present study is descriptive and retrospective covering the period from January 2017 to December 2017, the one year period. On 118 patients received in the service for clandestine abortion, 60 were retained for the study. The 58 other files were excluded because of not containing sufficient information for this study. The descriptive statistical analyses were applied for the data analysis. Results: The frequency of the allowed patients for complication of clandestine abortion caused at the Saint Joseph hospital of Kinshasa was 6.03%. The most concerned population with this practice was less than 15 years and more than 45 years;they were unmarried (41.6%) and nulliparous (41.6%) in most cases. Ancillary medical staff (especially nurses) was accused the most in this practice of the illegal abortion caused by the dilatation and curettage with 50%. The genital haemorrhage constitutes the principal complication and reason for consultation and accounted for 78.3%. The assumption of responsibility is primarily medical and surgical. The vital prognosis is satisfactory for the immediate one, because no death is noted. Conclusion: The clandestine abortion remains public health problem in our communities. The results found in our study call for certain reflections so that to reduce its frequency and to avoid its complications.

关键词： Abortions Clandestine Complications

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Selection of a Plotting Position for a Normal Q-Q Plot. R Script

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通讯和计算机（中英文版） 2012年第3期9卷 243-250页

作者： Castillo-Gutierrez Sonia Lozano-Aguilera Emilio Estudillo-martinez maria dolores Department of Statistics and Operations Research University of Jaen 23071 Jaen Spain

In this contribution an R script for the construction of a Normal Quantile-Quantile Plot or a Normal Q-Q Plot is presented. The assessing of the fit of a probability model to some sample data is performed by this probability plot. The Q-Q Plot compares the empirical quintiles of sample data with the corresponding quintiles of a theoretical distribution, previously selected. Specifically, the theoretical probability model considered in this paper is the normal distribution. Thus, the Normal Q-Q Plot is a graphical technique to assess whether a set of sample observations come from a normal distribution. The plotting positions are key elements in the construction of a Normal Q-Q Plot. The possibility for choosing between seven possible plotting positions is included in the R script developed. An example allows us to check the differences between these plotting positions and emphasizes the importance of these elements.

关键词： Q图脚本位置样本数据概率模型正态分布理论分布概率图

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A New Proposal to Adjust a Straight Line to a Normal Q-Q Plot

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Journal of Mathematics and System Science 2012年第5期2卷 327-333页

作者： Sonia Castillo-Gutierrez Emilio Damian Lozano-Aguilera maria dolores Estudillo-martinez Department of Statistics and Operations Research University of Jadn Jadn 23071 Spain

In this paper a new proposal of a straight line, the ＂modified Tukey＇s line＂, for fitting to a normal quantile-quantile Plot, or normal Q-Q plot, is presented. This probability plot allows us to determine whether a set of sample observations is distributed according to a normal distribution. For this, the sample quantiles are represented against the quantiles of a theoretical probability model, which in this case is the normal distribution. If the data set follows the above mentioned distribution, the plotted points will have a rectilinear configuration. To verify this, there are different alternatives for fitting a straight line to the plotted points. Among the straight lines which can be fitted to a Q-Q plot, in this paper, besides the proposed straight line, the following straight lines are considered： straight line that passes through the first and third quartiles, straight line that passes through the 10th and 90th percentiles, straight line fitted by the method of least squares, straight line with slope s and constant the average of the data set, Theil＇s line and Tukey＇s line. In addition, an example, in which there are represented the different straight lines considered and the proposed straight line on a normal Q-Q plot obtained for the same set of observations, is developed. In this example the existing differences among the straight lines are observed.

关键词： Normal Q-Q plot straight line modified Tukey's line.

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Rainfall Influence on the Abundance of Bacteria in Dubrovnik marine Waters

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Journal of Health Science 2018年第5期6卷 355-357页

作者： Antonia Mercep Andrej Jozinovic Lucia Stipicevic dolores Grilec marijana Pecarevic Department of Aquaculture University of Dubrovnik Cira Carica 4 Dubrovnik Croatia Institute of Public Health Dubrovnik-Neretva County Dr. Ante Sercera 4a Dubrovnik Croatia

Microbiological testing of the sea gives us great knowledge about its quality for swimming. Here we are following the fluctuations in the abundance of E. coli colonies, intestinal enterococci and total coliforms on three beaches in Dubrovnik during the rainfall in winter and spring. Three beaches Porporela, Banje and Excelsior are the most visited beaches during the summer season. Samples were taken before, during and after the rainfall on the surface, in the depth of 0.5 m and 1 m. Membrane filtration was used for sample treatment. Expected increase in the abundance of colonies is shown most on the Banje beach where the total coliforms increased 15.80 times while on the Excelsior beach E. coli colonies increased 12 times during the rainfall. On the Porporela beach there was a mild increase of intestinal enterococci colonies for 6.66 times. Regarding the data of the Institute of Public Health Dubrovnik-Neretva County the beaches were mostly marked as “excellent” especially since 2003 when the sewers were regulated in the Dubrovnik Old Town. The number of all colonies after the rainfall reduced for 99.80% in all three locations.

关键词： Bacteria sea for swimming rainfall

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