检索结果-南通市图书馆

Prognostic impact of inflammatory and nutritional biomarkers in pancreatic cancer

World Journal of Clinical Oncology 2025年第1期16卷 5-9页

作者： Macarena Teja maría I Garrido Abrahams Ocanto Felipe Counago Department of Radiation Oncology GenesisCare-San Francisco de Asís University HospitalMadrid 28002Spain Department of Radiation Oncology GenesisCare-Vithas La Milagrosa University HospitalMadrid 28010Spain national Director GenesisCare SpainMadrid 28043Spain Department of Medicine School of MedicineHealth and SportEuropean University of MadridMadrid 28670Spain

Pancreatic cancer is usually associated with a poor *** is the main curative treatment but pancreatic operations are aggressive and new tools that help clinicians to predict surgical and prognostic outcomes are *** et al recently published a retrospective,single centre cohort study evaluating the impact of seven nutritional and inflammatory markers in pancreatic cancer surgical patients:The albumin-to-globulin ratio,prognostic nutritional index(PnI),systemic immune-inflammation index(sII),neutrophil-to-lymphocyte ratio(nLR),platelet-to-lymphocyte ratio(PLR),nutritional risk index,and the geriatric nutritional risk index.A significant correlation was found between the PnI,sII,nLR,and PLR and a hospital discharge of less than 15 *** a univariable analysis,PnI,sII,nLR and PLR were significantly related to recurrence-free survival and,in a multivariable analysis PnI was associated with overall *** meta-analyses corroborate the results in terms of prognosis but individual studies are discordant on their ***,the cut-off values for these markers vary significantly between studies and there are no clinical trials comparing them to identify the most relevant *** are limitations when implementing nutritional and inflammatory biomarkers into clinical practice and further studies are needed in order to answer these questions.

关键词： Inflammatory biomarkers nutritional biomarkers Pancreatic cancer Prognosis surgical complications

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Extramedullary plasmacytoma with the uvula as first affected site:A case report

引用

World Journal of Clinical Oncology 2025年第1期16卷 53-58页

作者： Jing Yang Hui Peng sheng-Ke tu Min Li Kui song Department of Hematology The First Affiliated Hospital of Jishou UniversityJishou 416000Hunan ProvinceChina Department of Pharmacy The First Affiliated Hospital of Jishou UniversityJishou 416000Hunan ProvinceChina

BACKGROUnD Extramedullary plasmacytoma(EMP)represents one of the rarer forms of plasma cell malignancies,capable of impacting a variety of tissues and organs throughout the *** majority of EMP cases are predominantly found in the head and neck region,especially within the laryngopharynx,as well as in the gastrointestinal *** there have been documented instances of oropharyngeal involvement in EMP cases in the academic literature,it is important to note that EMP specifically affecting the uvula is exceedingly ***,it is noteworthy that over 60% of epithelial carcinomas in the upper respiratory tract and oropharynx tend to metastasize to the cervical lymph nodes,indicating a propensity for regional spread in these types of *** this context,we present a rare case of extramedullary plasmacytoma where the uvula served as the initially affected *** case emphasizes the need for heightened awareness among clinicians regarding such unusual comorbidities,as early recognition and diagnosis can significantly influence patient management and treatment *** addition,a review of the relevant literature is included to further educate and inform healthcare professionals about this rare presentation,ultimately aiming to enhance clinical understanding and improve patient care in similar *** sUMmarY A 51-year-old man was admitted to our hospital because of a slowly enlarging neck mass.A physical examination revealed a palpable left lymph node,and magnetic resonance imaging(MRI)of the oropharynx and the neck showed a soft tissue mass in the oropharynx and enlargement of multiple lymph nodes in the *** soft tissue mass was diagnosed as plasmacytoma by immunohistochemical *** immunoglobulins and bone marrow biopsy showed normal ***,we diagnosed that as EMP of the *** four cycles of adjuvant chemotherapy dominated by bortezomib,MRI reexamination showed a significant reduction of the mass

关键词： Extramedullary plasmacytoma Plasmacytoma Uvula Multiple myeloma Case report

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Causes and treatment of idiopathic benign paroxysmal positional vertigo based on endocrinological and other metabolic factors

引用

Journal of Otology 2020年第4期15卷 155-160页

作者： Joaquín Guerra jesús Devesa Otolaryngology Medical Center FoltraTravesía de Montouto 2415886TeoSpain scientific Direction Medical Center FoltraTravesía de Montouto 2415886TeoSpain

The genesis of the Benign Paroxysmal Positional Vertigo(BPPV)seems to be related to some metabolic *** factors,such as vitamin D,glucocorticoids,and even thyroid and growth hormones,can affect bone metabolism and the mineralization of *** also seems to link to factors related to aging or nutritional ***,since the incidence of BPPV is quantitatively higher in women than in men,female sex steroids could be associated with this *** could be useful to understand how these factors act in otoconial mineralization if we want to develop treatments aimed at preventing or delaying BPPV *** this review,we will analyze the role of these metabolic and hormonal factors in otoconial mineralization and in the treatment of BPPV.

关键词： Benign paroxysmal positional vertigo Otoconia Bone metabolism Vitamin D Estrogens GH

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Is the Export-led Growth Hypothesis Enough to Account for China's Growth?

引用

China & World Economy 2010年第4期18卷 34-51页

作者： maría jesús Herrerias Vicente Orts Department of Economics and lnstitut of International Economics Universitat Jaume I Department of Economics Universitat Jaume I

One of the missing pieces preventing us from understanding recent Chinese economic development is the role played by openness and capital accumulation in this process. The question is whether the sharp economic＇ growth that the Chinese economy has experienced is another case of export-led growth due to the open-door policy or whether, on the contrary, this growth has been caused by high domestic savings and investment rates （and the consequent capital accumulation）. To answer this question, we employed an empirical framework of the cointegrated vector autoregressive model. The empirical results show that both investment （in physieal capital and R＆D） and exports, as well as the exchange rate policy, are relevant factors in explaining China＇s long-run economic growth over the past 4 decades.

关键词： investment labor productivity openness output

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Brain-derived neurotrophic factor signaling in the neuromuscular junction during developmental axonal competition and synapse elimination

引用

neural Regeneration Research 2025年第2期20卷 394-401页

作者： Josep Tomàs Víctor Cilleros-Mañé Laia Just-Borràs marta Balanyà-segura Aleksandra Polishchuk Laura nadal marta Tomàs Carolina silvera-simón Manel M.santafé maria A.Lanuza Unitat d’Histologia i neurobiologia(UHneurob) Facultat de Medicina i Ciències de la SalutUniversitat Rovira i VirgiliReusSpain

During the development of the nervous system,there is an overproduction of neurons and *** competition between neighboring nerve endings and synapses performing different activity levels leads to their elimination or *** have extensively studied the involvement of the brain-derived neurotrophic factor-Tropomyosin-related kinase B receptor neurotrophic retrograde pathway,at the neuromuscular junction,in the axonal development and synapse elimination process versus the synapse *** purpose of this review is to describe the neurotrophic influence on developmental synapse elimination,in relation to other molecular pathways that we and others have found to regulate this *** particular,we summarize our published results based on transmitter release analysis and axonal counts to show the different involvement of the presynaptic acetylcholine muscarinic autoreceptors,coupled to downstream serine-threonine protein kinases A and C(PKA and PKC)and voltage-gated calcium channels,at different nerve endings in developmental *** dynamic changes that occur simultaneously in several nerve terminals and synapses converge across a postsynaptic site,influence each other,and require careful studies to individualize the mechanisms of specific *** describe an activity-dependent balance(related to the extent of transmitter release)between the presynaptic muscarinic subtypes and the neurotrophin-mediated TrkB/p75nTR pathways that can influence the timing and fate of the competitive interactions between the different axon *** downstream displacement of the PKA/PKC activity ratio to lower values,both in competing nerve terminals and at postsynaptic sites,plays a relevant role in controlling the elimination of supernumerary ***,calcium entry through L-and P/Q-subtypes of voltage-gated calcium channels(both channels are present,together with the n-type channel in developing nerve terminals)contributes to red

关键词： acetylcholine release adenosine receptors axonal competition brain-derived neurotrophic factor calcium channels motor end-plate muscarinic acetylcholine receptors postnatal synapse elimination serine kinases tropomyosin-related kinase receptorB

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

saturation effect of up-conversion luminescence from erbium-doped,silicatitania sol-gel powders

引用

Journal of Rare Earths 2011年第5期29卷 420-425页

作者： jesús Castaeda Guadalajara University Los Lagos University Center

The intensity of the visible up-conversion luminescence could be limited by a saturation effect produced by increased pump power. Visible up-conversion luminescence was obtained in erbium doped,silica-titania sol gel powders under dynamical pumping at 1532 nm. The saturation effect was studied for erbium radiative transitions 2H9/2→4I15/2 （410 nm）,2H11/2→4I15/2 （530 nm）,4s3/2→4I15/2 （550 nm）,2H9/2→4I13/2 （567 nm） and 4F9/2→4I15/2 （675 nm）. The recorded up-conversion luminescence decreased when increasing excitation power. The results suggested that the saturation effect was determined by the pump power,the sample composition and the lifetimes of the corresponding first excited states.

关键词： erbium up-conversion luminescence saturation rare earths

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Estimation of the carbon pool in soil and above-ground biomass within mangrove forests in southeast Mexico using allometric equations

引用

Journal of Forestry Research 2014年第1期25卷 129-134页

作者： jesús Jaime Guerra-santos Rosa maría Cerón-Bretón Julia Griselda Cerón-Bretón Diana Lizett Damián-Hernández Reyna Cristina sánchez-Junco Emma del Carmen Guevara Carrió Centro de Investigación de Ciencias Ambientales-Universidad Autónoma del Carmen Av.Abasolo s/n.Col.Renovación 2da.Sección C.P.24180.Cd.del CarmenCampecheMéxico

We report the results of carbon stored in soil and aboveground biomass from the most important area of mangroves in Mexico, with dominant vegetation of Red mangrove （Rhizophora mangle L.）, Black mangrove （Avicennia germinans L.）, white mangrove （Laguncularia racemosa Gaertn.） and button mangrove （Conocarpus erectus L.）. We sampled soils with high fertility during the dry season in 2009 and 2010 at three sites on Atasta Peninsula, Campeche. We used allometric equations to estimate above ground biomass （AGB） of trees. AGB was higher in C. erectus （253.18±32.17 t？ha-1）, lower in A. germinans （161.93±12.63 t？ha-1）, and intermediate in R. mangle （181.70±16.58 t？ha-1） and L. racemosa （206.07±19.12 t？ha-1）. Of the three studied sites, the highest absolute value for AGB was 279.72 t？ha-1 in button mangrove forest at any single site. Carbon stored in soil at the three sites ranged from 36.80±10.27 to 235.77±66.11 t？ha-1. The tukey test （p 〈0.05） made for AGB was higher for black mangrove showed significant differences in soil carbon content between black mangrove and button mangrove. C. erectus had higher AGB compared with the other species. A. germinans trees had lower AGB because they grew in hypersaline environments, which reduced their development. C. erectus grew on higher ground where soils were richer in nutrients. AGB tended to be low in areas near the sea and increased with distance from the coast. A. germinans usually grew on recently deposited sediments. We assumed that all sites have the same potential to store carbon in soil, and then we found that there were no significant differences in carbon content between the three samples sites： all sites had potential to store carbon for long periods. Carbon storage at the three sampling sites in the state of Campeche, Mexico, was higher than that reported for other locations.

关键词： carbon storage Rhizophora mangle Laguncularia racemosa,Avicennia germinans tree biomass

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Fagus sylvatica and Quercus pyrenaica:Two neighbors with few things in common

引用

Forest Ecosystems 2023年第2期10卷 162-175页

作者： sergio de Tomás marín jesús Rodríguez-Calcerrada salvador Arenas-Castro Iván Prieto Guillermo González Luis Gil Enrique G.de la Riva Department of Ecology Brandenburgische Technische Universität Cottbus-SenftenbergKonrad-Wachsmann-Allee 603046CottbusGermany Forest Genetics and Ecophysiology Research Group School of Forestry EngineeringUniversidad Politécnica de MadridMadridSpain Area of Ecology Botany DepartmentEcology and Plant PhysiologyFaculty of SciencesUniversidad de CórdobaCórdobaSpain Ecology Department Faculty of Biology and Environmental SciencesUniversidad de LeónLeónSpain

Background:The Iberian Peninsula comprises one of the largest boundaries between Mediterranean and Eurosiberian vegetation,known as sub-Mediterranean *** ecotone hosts many unique plant species and communities and constitutes the low-latitude(warm)margin of numerous central European species which co-occur with Mediterranean *** of the main species found in this region are the Eurosiberian European beech(Fagus sylvatica L.)and the Mediterranean Pyrenean oak(Quercus pyrenaica Willd.).It remains unclear how the different physiological and adaptive strategies of these two species reflect their niche partitioning within a subMediterranean community and to what extent phenotypic variation(intraspecific variability)is driving niche partitioning across Eurosiberian and Mediterranean ***:We quantified functional niche partitioning,based on the n-dimensional hypervolume to nine traits related to resource acquisition strategies(leaf,stem and root)plus relative growth rate as an additional wholeplant trait,and the environmental niche similarity between Pyrenean oak and European ***,we analyzed the degree of phenotypic variation of both target species and its relationship with relative growth rates(RGR)and environmental *** recruitment was measured for both target species as a proxy for the average ***:species’functional space was highly segregated(13.09%overlap),mainly due to differences in niche breadth(59.7%)rather than niche replacement(25.6%),and beech showed higher trait variability,i.e.,had larger functional ***,both species shared the environmental space,i.e.,environmental niches were *** plant traits were not related to abiotic variables or RGR,neither did RGR to plant ***:Both target species share similar environmental space,however,show notably different functional resource-use strategies,promoting a high complementarity that contributes to maintaining a high functiona

关键词： Environmental niche European beech Forest dynamics Functional niche Hypervolume Pyrenean oak species coexistence sub-Mediterranean community

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Comparison of heuristic and deep learning-based methods for ground classification from aerial point clouds

引用

International Journal of Digital Earth 2020年第10期13卷 1115-1134页

作者： mario soilán Belén Riveiro jesús Balado Pedro Arias Department of Materials Engineering Applied Mechanics and ConstructionSchool of Industrial EngineeringUniversity of VigoVigoSpain Department of natural Resources and Environmental Engineering School of Mining EngineeringUniversity of VigoVigoSpain

The automatic definition of the ground from 3D point clouds has been a common process for the last two decades,with many different approaches and applications that can be found in a vast *** paper presents a comparison of three different methodological concepts for ground classification,in order to establish the advantages and drawbacks of each ***,a heuristic method,based on previous knowledge of the geometry and context of the 3D ***,a Deep Convolutional network based on segnet that classifies 2D images generated from the 3D point ***,the third method applies a Deep Learning classification based on Pointnet,which takes 3D points directly as *** validate each method and compare them,public and labelled point clouds from the Actueel Hoogtebestand nederland dataset are ***,the three methods are validated against the IsPRs 3D semantic Labeling Contest *** results obtained show that the deep learning-based approaches outperform the heuristic method,with F-scores above 96%.The best results were obtained using a shallower version of segnet,with F-score above 97%.

关键词： Ground classification aerial point cloud deep learning point cloud processing

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

APRI as a predictor of early viral response in chronic hepatitis C patients

引用

World Journal of Gastroenterology 2009年第39期15卷 4923-4927页

作者： José A Mata-marín José L Fuentes-Allen jesús Gaytán-martínez Bulmaro Manjarrez-Téllez Alberto Chaparro-sánchez Carla I Arroyo-Anduiza Infectious Diseases Department Hospital de Infectología"La Raza"National Medical CenterIMSS Clinical Pathology Department Hospital General "La Raza"National Medical CenterIMSS

AIM:To evaluate the aspartate aminotransferase(AsT) to platelet ratio index(APRI) as a predictive factor of early viral response in chronic hepatitis C naive ***:We performed an ambispective case-control *** enrolled chronic hepatitis C naive patients who were evaluated to start therapy with PEGylated interferon α-2b(1.5 μg/kg per week) and ribavirin(>75 kg:1200mg and nts were allocated into two groups,group 1:Hepatitis C patients with early viral response(EVR),group 2:Patients without *** ratio(OR) and 95% confi dence interval(CI) were calculated to assess the relationship between each risk factor and the EVR in both ***:During the study,80 patients were analyzed,45 retrospectively and 35 *** mean ± sD age of our subjects was 42.9 ± 12 years;weight 70 kg(±11.19),AsT 64.6 IU/mL(±48.74),alanine aminotransferase(ALT) 76.3 IU/mL(±63.08) and platelets 209000 mill/mm3(±84 429).Fifty-five(68.8%) were genotype 1 and 25(31.3%) were genotype 2 or 3;the mean hepatitis C virus RnA viral load was 2 269 061 IU/mL(±7220266).In the univariate analysis,APRI was not associated with EVR [OR 0.61(95% CI 0.229-1.655,P=0.33)],and the absence of EVR was only associated with genotype 1 [OR 0.28(95% CI 0.08-0.94,P=0.034)].After adjustment in a logistic regression model,genotype 1 remains signifi ***:APRI was not a predictor of EVR in chronic hepatitis C;Genotype 1 was the only predictive factor associated with the absence of EVR in our patients.

关键词： Hepatitis C virus viral load Viral genotype Hepatitis C Aspartate aminotransferase to platelet ratio index Early viral response

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：