检索结果-南通市图书馆

Preparation of a Slow Release Biofertilizer From a Polymeric Urea-Formaldehyde Matrix (PUFM)

在线全文

学校读者我要写书评

暂无评论

Phyton-international Journal of Experimental Botany 2019年第4期88卷 459-470页

作者： Laura Siverio martínez Mayra González Hurtado Laura M.Castro González Jacques Rieumont Briones Ariel martínez García maría i.hernández díaz institute of Materials Science and Technology Polymer LaboratoryUniversity of HavanaZapata and GC.P.10400C.Havana CityCuba National Autonomous University of Mexico Department of Physical and Theoretical Chemistry CoyoacanDistrito FederalMX Faculty of Chemistry University of HavanaDepartment of Physical ChemistryZapata and GC.P.10400Havana CityCuba institute of Horticultural Research Liliana dimitrova Quivicánkm 33½.Havana CityCuba

Fertilizers industry faces the challenge of improving the efficiency of its products either by optimizing the fertilizers in use or by developing new types of *** the last decade,controlled and slow release technologies have become more *** technologies aim to increase the efficiency of the applied substance by increasing its action over time and avoiding losses of all kinds(leaching,volatilization).The main purpose of the current study was to obtain a slow release biofertilizer by incorporating microalgae into a polymeric urea-formaldehyde matrix(PUFM).The quantitative analysis of macronutrients and micronutrients in the microalgae was determined using different techniques including titration,UV and Atomic Adsorption *** matrix and the formulation obtained(PUFM+CHLO)were also characterized by infrared Spectroscopy(FTiR)and Scanning Electron Microscopy(SEM).The“in vitro”study showed a typical slow release behavior of nitrogen(N),phosphorus(P)and potassium(K)*** was also shown that(PUFM+CHLO)formulation has the slowest macronutrients release time with a maximum release of 28%,26%y 46%for(N-P-K)macronutrients respectively during a period of 30 ***"in vivo"study exposed the benefits of the biofertilizer formulation(PUFM+CHLO)from conventional commercial fertilizer(CF)(NPK-14-5-12).due to the presence of nutrients of natural origin in microalgae,(PUFM+CHLO)shows ecological effects which could also developing sustainable agriculture systems.

关键词： Slow-release fertilizer microalgae polymeric matrix nutrients

Role of lipids in the control of autophagy and primary cilium signaling in neurons

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2024年第2期19卷 264-271页

作者： maría Paz hernández-Cáceres daniela Pinto-Nuñez Patricia Rivera Paulina Burgos Francisco díaz-Castro Alfredo Criollo maria Jose Yañez Eugenia Morselli instituto de investigación en Ciencias Odontológicas(iCOd) Facultad de OdontologíaUniversidad de ChileSantiagoChile department of Basic Sciences Faculty of Medicine and ScienceUniversidad San SebastiánSantiagoChile Physiology department Faculty of Biological SciencesPontificia Universidad Católica de ChileSantiagoChile Advanced Center for Chronic diseases(ACCdiS) Facultad de Ciencias Químicas y Farmacéuticas&Facultad de MedicinaUniversidad de ChileSantiagoChile Autophagy Research Center SantiagoChile

The brain is,after the adipose tissue,the organ with the greatest amount of lipids and diversity in their composition in the human *** neurons,lipids are involved in signaling pathways controlling autophagy,a lysosome-dependent catabolic process essential for the maintenance of neuronal homeostasis and the function of the primary cilium,a cellular antenna that acts as a communication hub that transfers extracellular signals into intracellular responses required for neurogenesis and brain development.A crosstalk between primary cilia and autophagy has been established;however,its role in the control of neuronal activity and homeostasis is barely *** this review,we briefly discuss the current knowledge regarding the role of autophagy and the primary cilium in *** we review the recent literature about specific lipid subclasses in the regulation of autophagy,in the control of primary cilium structure and its dependent cellular signaling in physiological and pathological conditions,specifically focusing on neurons,an area of research that could have major implications in neurodevelopment,energy homeostasis,and neurodegeneration.

关键词： autophagic flux cholesterol fatty acids GPCR lysosomal storage diseases neurons NPC1 phosphoinositides primary cilium

Topical ocular administration of dPP-Ⅳ inhibitors:a new approach for treating diabetes-induced retinal neurodegeneration

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2024年第4期19卷 713-714页

作者： Rafael Simó Cristina hernández diabetes and Metabolism Research Unit Vall d’Hebron Research Institute(VHIR) department of Medicine Autonomous University of Barcelona Centro de investigación Biomédica en Red de diabetes y Enfermedades Metabólicas Asociadas(CiBERdEM) Instituto de Salud CarlosⅢ(ICSⅢ)

Retinal neurodegeneration plays a significant role in the pathogenesis of diabetic retinopathy(dR),the leading cause of preventable *** fact,the American diabetes Association has defined dR as a highly specific neurovascular complication(Solomon et al.,2017).Therefore,it is no longer acceptable to consider dR as merely a microvascular *** this regard,the term diabetic retinal disease(dRd)has been proposed as a broader term comprising microangiopathy and ***,there are currently no treatments available that directly target the neurodegenerative changes of *** paper will give new insights into the translational research in this field with particular emphasis on glucagon-like peptide 1/dipeptidyl peptidase iV(GLP-1/dPP-iV)inhibitors.

关键词： neurodegeneration ocular insight

Refractive outcomes after V4c Toric collamer lens implantation over 1y of follow-up

在线全文

学校读者我要写书评

暂无评论

international Journal of Ophthalmology(English edition) 2024年第7期17卷 1322-1330页

作者： Humberto Carreras-díaz Josefina Reñones de Abajo maría del Rosario Carreras-díaz Amalia Lorente-Velázquez Vithas Eurocanarias Las Palmas de Gran Canaria 35004Spain University Hospital of Girona doctor Josep Trueta Gerona 17007Spain departament of Optometry and Vision Faculty of Optics and OptometryComplutense University of MadridMadrid 28040Spain

AiM:To evaluate refractive outcomes and corneal astigmatism changes after Toric implantable collamer lens with a central port(V4c T-iCL)implantation over 1y of ***:A retrospective study was performed including 50 eyes of 50 patients that underwent V4c T-iCL ***(UdVA)and corrected(CdVA)distance visual acuities,refraction,refractive and corneal astigmatism changes and corneal coupling correction were evaluated preoperatively,1 and 12mo *** analysis was used for astigmatism *** of adjustment(CAdj)was calculated for corneal coupling ***:The mean UdVA achieved was 0.03 logmar at 1mo and remained unchanged throughout the whole follow-up(P=0.193).At the last visit,84%of the eyes achieved a CdVA of 0.00 logmar or *** spherical equivalent refraction(SEQ),96%of eyes were ranges of±1.00 d and 84%of them within±0.50 ***,94%of eyes had a remaining refractive cylinder within±1.00 d and 78%of them within±0.50 ***,SEQ and refractive cylinder,remain stable over the postoperative follow-up(P=1.000 and P=0.660,respectively).in terms of surgically induced astigmatism(SiA),no statistically significant differences were found over the follow-up(P=0.102)and under correction was found with a correction index lower than the unit at each visit.A keratometric astigmatism induced of 0.59±0.53(vector mean:0.26×73º)d was reached at the last *** significant changes in terms of corneal astigmatism orientation were reported over post-surgery visits(P=0.129 and P=0.097 at 1 and 12mo respectively).No clinical significance was found for CAdj on with-the-rule *** postoperative complications resulting from the surgery were ***:Refractive outcomes suggest that the V4c T-iCL implantation for correction of myopic astigmatism was satisfactory in terms of effectiveness,safety,and stability during 1y of *** astigmatism induced by the incision around 0.5 d is achieved

关键词： V4c Toric collamer lens corneal astigmatism surgically induced astigmatism corneal coupling

dNA metabarcoding reveals seasonal changes in diet composition across four arthropod-eating lizard species(Phrynosomatidae:Sceloporus)

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

integrative Zoology 2024年第3期19卷 480-495页

作者： Mauricio hernÁndez Stephanie HEREiRA-PACHECO Antton ALBERdi Aníbal H.dÍaz dE LA VEGA-PÉREZ Arturo ESTRAdA-TORRES Sergio ANCONA Yendi E.NAVARRO-NOYA doctorado en Ciencias Biológicas Centro Tlaxcala de Biología de la ConductaUniversidad Autónoma de TlaxcalaTlaxcalaMexico Estación Científica La Malinche Centro Tlaxcala de Biología de la ConductaUniversidad Autónoma de TlaxcalaTlaxcalaMexico Center for Evolutionary Hologenomics The Globe InstituteUniversity of CopenhagenCopenhagenDenmark Consejo Nacional de Ciencia y Tecnología-Centro Tlaxcala de Biología de la Conducta Universidad Autónoma de TlaxcalaTlaxcalaMexico departamento de Ecología Evolutiva Instituto de EcologíaUniversidad Nacional Autónoma de MéxicoMexico CityMexico Laboratorio de interacciones Bióticas Centro de Investigación en Ciencias BiológicasUniversidad Autónoma de TlaxcalaSan Felipe IxtacuixtlaTlaxcalaMexico

diet composition and its ecological drivers are rarely investigated in coexisting closely related *** used a molecular approach to characterize the seasonal variation in diet composition in four spiny lizard species inhabiting a mountainous *** metabarcoding revealed that the lizards Sceloporus aeneus,***,***,and *** mostly consumed arthropods of the orders Hemiptera,Araneae,Hymenoptera,and *** terrestrial lizards *** and *** mostly predated ants and spiders,whereas the arboreal–saxicolous *** and saxicolous *** largely consumed grasshoppers and *** taxonomic and phylogenetic diversity of the prey was higher during the dry season than the rainy season,likely because reduced prey availability in the dry season forced lizards to diversify their diets to meet their nutritional *** and phylogenetic composition varied seasonally depending on the species,but only dietary composition varied with *** dietary turnover was greater in *** than in ***,suggesting site-specific seasonal variability in prey availability;no other differences among species were ***,which lives at the highest altitude in our study site,displayed interseasonal variation in diet *** differences were correlated with the species’feeding strategies and elevational distribution,which likely contributed to the coexistence of these lizard species in the studied geographic area and beyond.

关键词： arthropod-eating lizards diet breadth environmental barcoding mountainous ecosystem seasonal dietary shifts

Tracking the change in Spanish greenhouse gas emissions through an LMdi decomposition model:A global and sectoral approach

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Environmental Sciences 2024年第5期139卷 114-122页

作者： Paula Fernández González maría José Presno Manuel Landajo department of Applied Economics University of OviedoAuda del Cristos/n 33011 OviedoSpain

The reduction of GHG emissions to reverse the greenhouse effect is one of the main challenges in this *** this paper we pursue two ***,we analyze the evolution of GHG emissions in Spain in 2008–2018,at both the global and sectoral levels,with the variation in emissions decomposed into a set of determining ***,we propose several actions specifically oriented to more tightly controlling the level of *** results showed a remarkable reduction(18.44%)in GHG emissions,mainly due to the intensity effect,but also to the production-per-capita *** detected somewhat different patterns among the various sectors *** the intensity effect was the most influential one in the agricultural,transport,and others sectors,the production-per-capita effect was predominant in the case of *** carbonization effect was revealed as crucial in the commerce *** above findings highlight the importance of the energy efficiency measures taken in recent years in the Spanish economy,also pointing to the need to deepen those strategies and to propose new measures that entail greater efficiency in *** efforts in areas like innovation,R&d,diffusion of more eco-friendly technologies,and a greater use of greener energies all prove to be essential reduction actions to fight the greenhouse effect.

关键词： LMdi decomposition Spain GHG emissions

Resilience to structural and molecular changes in excitatory synapses in the hippocampus contributes to cognitive function recovery in Tg2576 mice

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2024年第9期19卷 2068-2074页

作者： Carolina Aguado Sara Badesso Josémartínez-hernández Alejandro martín-Belmonte Rocío Alfaro-Ruiz Miriam Fernández Ana Esther Moreno-martínez mar Cuadrado-Tejedor Ana García-Osta Rafael Luján Synaptic Structure Laboratory Instituto de Investigación en Discapacidades Neurológicas(IDINE)Department of Medical SciencesFacultad de MedicinaUniversidad de Castilla-La ManchaCampus BiosanitarioAlbaceteSpain Gene Therapy for Neurological disease Program Center for Applied Medical Research(CIMA)University of NavarraInstituto de Investigación Sanitaria de Navarra(IdiSNA)PamplonaSpain Pharmacology Unit Department of Pathology and Experimental TherapeuticsFaculty of Medicine and Health SciencesInstitute of NeurosciencesUniversity of BarcelonaBarcelonaSpain Neuropharmacology and Pain Group Neuroscience ProgramInstitut d’InvestigacióBiomèdica de BellvitgeIDIBELLL’Hospitalet de LlobregatSpain department of Pathology Anatomy and PhysiologySchool of MedicineUniversity of NavarraPamplonaSpain UniversitéGrenoble Alpes Grenoble Institut des NeurosciencesGrenobleFrance

Plaques of amyloid-β(Aβ)and neurofibrillary tangles are the main pathological characteristics of Alzheimer’s disease(Ad).However,some older adult people with Ad pathological hallmarks can retain cognitive *** the factors that lead to this cognitive resilience to Ad offers promising prospects for identifying new therapeutic *** hypothesis focuses on the contribution of resilience to changes in excitatory synapses at the structural and molecular levels,which may underlie healthy cognitive performance in aged Ad *** the Morris Water Maze test,we selected resilient(asymptomatic)and cognitively impaired aged Tg2576 *** the enzyme-linked immunosorbent assay showed similar levels of Aβ42 in both experimental groups,western blot analysis revealed differences in tau pathology in the pre-synaptic supernatant *** further investigate the density of synapses in the hippocampus of 16-18 month-old Tg2576 mice,we employed stereological and electron microscopic *** findings indicated a decrease in the density of excitatory synapses in the stratum radiatum of the hippocampal CA1 in cognitively impaired Tg2576 mice compared with age-matched resilient Tg2576 and non-transgenic ***,through quantitative immunoelectron microscopy in the hippocampus of impaired and resilient Tg2576 transgenic Ad mice,we uncovered differences in the subcellular localization of glutamate ***,the density of GluA1,GluA2/3,and mGlu5 in spines and dendritic shafts of CA1 pyramidal cells in impaired Tg2576 mice was significantly reduced compared with age-matched resilient Tg2576 and non-transgenic ***,the density of GluA2/3 in resilient Tg2576 mice was significantly increased in spines but not in dendritic shafts compared with impaired Tg2576 and non-transgenic *** subcellular findings strongly support the hypothesis that dendritic spine plasticity and synaptic machinery in the hippocampus play cr

关键词： aging Alzheimer´s disease cognitive hippocampus immunoelectron microscopy resilience synapse

Liquid biopsy for gastric cancer:Techniques,applications,and future directions

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2024年第12期30卷 1680-1705页

作者： Cristina díaz del Arco M Jesús Fernández Aceñero Luis Ortega Medina department of Surgical Pathology Health Research Institute of the Hospital Clínico San CarlosHospital Clínico San CarlosMadrid 28040Spain department of Legal Medicine Psychiatry and PathologyUniversidad Complutense de MadridMadrid 28040Spain

After the study of circulating tumor cells in blood through liquid biopsy(LB),this technique has evolved to encompass the analysis of multiple materials originating from the tumor,such as nucleic acids,extracellular vesicles,tumor-educated platelets,and other ***,research has extended to include the examination of samples other than blood or plasma,such as saliva,gastric juice,urine,or *** techniques are diverse,intricate,and *** must be highly sensitive,and pre-analytical,patient,and tumor-related factors significantly influence the detection threshold,diagnostic method selection,and potential ***,the implementation of LB in clinical practice still faces several *** potential applications of LB range from early cancer detection to guiding targeted therapy or immunotherapy in both early and advanced cancer cases,monitoring treatment response,early identification of relapses,or assessing patient *** the other hand,gastric cancer(GC)is a disease often diagnosed at advanced *** recent advances in molecular understanding,the currently available treatment options have not substantially improved the prognosis for many of these *** application of LB in GC could be highly valuable as a non-invasive method for early diagnosis and for enhancing the management and outcomes of these *** this comprehensive review,from a pathologist’s perspective,we provide an overview of the main options available in LB,delve into the fundamental principles of the most studied techniques,explore the potential utility of LB application in the context of GC,and address the obstacles that need to be overcome in the future to make this innovative technique a game-changer in cancer diagnosis and treatment within clinical practice.

关键词： Liquid biopsy Gastric cancer Circulating tumor cells Cell-free dNA Circulating tumor dNA Molecular

deep optics preconditioner for modulation-free pyramid wavefront sensing

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Photonics Research 2024年第2期12卷 301-312页

作者： FELiPE GUZMÁN JORGE TAPiA CAMiLO WEiNBERGER NiCOLÁS hernÁndez JORGE BACCA BENOiT NEiCHEL ESTEBAN VERA School of Electrical Engineering Pontificia Universidad Católica de Valparaı´soValparaı´soChile department of Systems Engineering Universidad Industrial de SantanderBucaramangaColombia Laboratoire d’Astrophysique de marseille MarseilleFrance

The pyramid wavefront sensor(PWFS)can provide the sensitivity needed for demanding adaptive optics applications,such as imaging exoplanets using the future extremely large telescopes of over 30 m of diameter(d).However,its exquisite sensitivity has a limited linear range of operation,or dynamic range,although it can be extended through the use of beam modulation—despite sacrificing sensitivity and requiring additional optical *** by artificial intelligence techniques,this work proposes to train an optical layer—comprising a passive diffractive element placed at a conjugated Fourier plane of the pyramid prism—to boost the linear response of the pyramid sensor without the need for cumbersome *** develop an end-2-end simulation to train the diffractive element,which acts as an optical preconditioner to the traditional least-square modal phase estimation *** results with a large range of turbulence conditions show a noticeable improvement in the aberration estimation performance equivalent to over 3λ∕d of modulation when using the optically preconditioned deep PWFS(dPWFS).Experimental results validate the advantages of using the designed optical layer,where the dPWFS can pair the performance of a traditional PWFS with 2λ∕d of *** and adding an optical preconditioner to the PWFS is just the tip of the iceberg,since the proposed deep optics methodology can be used for the design of a completely new generation of wavefront sensors that can better fit the demands of sophisticated adaptive optics applications such as ground-to-space and underwater optical communications and imaging through scattering media.

关键词： process optics pyramid