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Storage time and condensed tannin content of high-moisture sorghum grains:Effects on in vitro fermentation and mold populations

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Animal Nutrition 2020年第1期6卷 92-97页

作者： Carmen García y Santos Lina Bettucci Sebastián Brambillasca cecilia Cajarville Laboratorio de Toxicología Facultad de VeterinariaUniversidad de la RepúblicaLasplaces 1550PC 11.600MontevideoUruguay Laboratorio de Micología Facultad de Ciencias-Facultad de IngenieríaUniversidad de la RepúblicaJulio Herrera y Reissig 565PC 11.300MontevideoUruguay Instituto de Producción Animal Facultad de VeterinariaUniversidad de la RepúblicaRuta 1km 42.200PC 80.100San JoseUruguay

Silage of high moisture sorghum grains is a highly relevant source of energy in cattle production systems in South *** is little information related to the chemical characteristics,the kinetics of fermentation and the toxic fungal populations of these *** aim of this study was to evaluate the effect of storage time and condensed tannins content of the grain on chemical composition,in vitro fermentation parameters,and toxicogenic fungal populations of moist sorghum grain stored in *** of 2 varieties of sorghum grains(high-tannin[HT]and low-tannin[LT]),were obtained during the grain harvest before silage making and after 30,90,and 180 d of storage(n=16).High-tannin grains had higher acid detergent fiber,tannins,gas production(P<0.05)and lower starch and rate of gas production(P<0.01).Interaction variety x storage time were observed for all chemical parameters(P<0.01),except for neutral detergent fiber assayed with a heat stable amylase and expressed inclusive of residual ash(aNDF)and *** and protein content increased in both varieties,tannins decreased in HT and LT,and organic matter(OM)increased in HT and declined in LT(P<0.05).The rate of gas production increased with the storage time for HT and LT(P<0.01).A linear reduction in the Aspergillus number of colonies in the HT varieties was observed(P<0.01),whereas a linear increase in Penicillium isolation was detected in the LT sorghums(P<0.01).The storage time was beneficial in terms of decreasing the condensed tannins,increasing fractional rate of gas production and minimizing fungal contamination,particularly on HT grains.

关键词： Sorghum grains silages Condensed tannins Toxicogenic fungal populations Storage time

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Modelling fuel loads of understorey vegetation and forest floor components in pine stands in NW Spain

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Forest Ecosystems 2022年第6期9卷 775-789页

作者： Jose A.Vega Stefano Arellano-Perez Juan Gabriel Alvarez-Gonzalez Cristina Fernandez Enrique Jimenez Pedro Cuinas Jose maría Fernandez-Alonso Daniel J.Vega-Nieva Fernando Castedo-Dorado cecilia Alonso-Rego Teresa Fontúrbel Ana Daría Ruiz-Gonzalez Centro de Investigacion Forestal de Lourizan PO Box 12736080PontevedraSpain Unidad de Gestion Ambiental y Forestal Sostenible(UXAFORES) Departamento de Ingeniería AgroforestalEscuela Politecnica Superior de IngenieríaUniversidad de Santiago de CompostelaCampus Universitario s/n27002LugoSpain Facultad de Ciencias Forestales Universidad Juarez del Estado de DurangoRío Papaloapan y Blvd.Durango s/nCol.Valle del Sur34120DurangoMexico Departamento de Ingeniería y Ciencias Agrarias Universidad de LeonCampus de Ponferrada24401PonferradaSpain

In this study,310 destructively sampled plots were used to develop two equation systems for the three main pine species in NW Spain(***;*** and ***):one for estimating loads of understorey fuel components by size and condition(live and dead)and another one for forest floor *** systems of equations were simultaneously fitted for estimating fuel loads using overstorey,understorey and forest floor variables as *** systems of equations included both the effect of pine species and the effect of understorey compositions dominated by ferns-brambles or by woody species,due to their obvious structural and physiological *** general,the goodness-of-fit statistics indicated that the estimates were reasonably robust and accurate for all of the fuel *** best results were obtained for total understorey vegetation,total forest floor and raw humus fuel loads,with more than 76%of the observed variability explained,whereas the poorest results were obtained for coarse fuel loads of understory vegetation with a 53%of observed variability *** reduce the overall costs associated with the field inventories necessary for operational use of the models,the additive systems were fitted again using only overstorey variables as potential *** relationships for fine(<6 mm)and total understorey vegetation and total forest floor fuel loads were obtained,indicating the complexity of the forest overstorey-understorey and overstorey-forest floor ***,these models explained around 52%of the observed ***,equations estimating the total understorey vegetation and the total forest floor fuel loads based only on canopy cover were *** models explained only 26%-32%of the observed variability;however,their main advantage is that although understorey vegetation in forested landscapes is largely invisible to remote sensing,canopy cover can be estimated with moderate accuracy,allowin

关键词： Area-based approach Additive equation systems Live and dead fine fuel Pinus pinaster Pinus radiata Pinus sylvestris

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Degenerative Mitral Valve Repair： From Etiology, Pathology, Surgical Strategy to Durability

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Chinese Medical Journal 2018年第20期131卷 2486-2488页

作者： Hong-Guang Fan cecilia marcacci Filip Dulguerov Gilles D Dreylus Department of Cardiovascular Surgery Fuwai Hospital Peking Union Medical College and Chinese Academy of Medical Sciences Beijing 100037 China Cardio-Thoracic Center of Monaco Monte Carlo 98000 Monaco

To the Editor： Degenerative mitral valve disease is a common disorder afflicting 2-3 % of the general population and nearly half of them are elderly. Plenty of studies have confirmed that mitral repair would result ... 详细信息

关键词： PROLAPSE

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Antimicrobial Activity against Escherichia coli of Cu-Ni Nanoalloy and Combination of Ag Nanoparticles,Obtained by Different Method

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Journal of Pharmacy and Pharmacology 2021年第12期9卷 420-427页

作者： cecilia A.Fernandez Yamila AIllanez Gaston Fernandez marcelo R.Esquivel maría de los ACangiano Research Institute of Chemical Technology(INTEQUI) National University of San Luis(UNSL)-CONICET.Almirante Brown 1455San Luis 5700Argentina School of Engineering and Farming Sciences(FICA) National University of San Luis(UNSL)Ruta 55 Ext.NorteVilla MercedesSan Luis5730Argentina School of Chemistry Biochemistry and PharmacyUNSLSan LuisArgentina School of Medical Sciences of the Catholic University of Cuyo San LuisArgentina Atomic Center of Bariloche(CNEA-CONICET) Avenida Bustillo km 95BarilocheRío Negro8400Argentina National University of Comahue(UNCo)-Bariloche Quintral 1250BarilocheRío Negro8400Argentina

Escherichia coli,is a pathogenic bacterium that causes serious infections,whose therapeutic treatment is threatened by the emergence of multiple resistance to conventional *** recent years,metal nanoparticles(NPs)have been studied for their antimicrobial capacity and their possible applications as an alternative to antibiotics against different *** also vary in synthesis techniques;either by chemical,physical and biological *** objective of this work was to study the possible antimicrobial capacity of Cu-Ni nanoalloys obtained by a method called *** antimicrobial capacity of the NPs mentioned above was evaluated in vitro by the agar diffusion *** of the NPs evaluated showed antibacterial activity against the strain of *** *** combining chemical and biological NP,synergistic effects are observed with an increase in antibacterial activity in some *** can conclude that NPs derived from chemical and biological synthesis could be used as antimicrobials against *** and when these are combined,antibacterial effects *** the future,these applications of nanomaterials could be used as an alternative to the use of antibiotics against infections that have limited treatments.

关键词： Nanoalloys Cu-Ni antibacterial activity human pathogens nanotechnology

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5-Azacytidine induces changes in electrophysiological properties of human mesenchymal stem cells

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Cell Research 2006年第12期16卷 949-960页

作者： Bartosz Balana cecilia Nicolett Ihor Zahanich Eva M Graf Torsten Christ Sabine Boxberger Department of Pharmacology and Toxicology Medical Clinic I Medical FacultyDresden University of TechnologyFetscherstr.74D-01307 DresdenGermany

Previously,mouse bone marrow-derived stem cells（MSC）treated with the unspecific DNA methyltransferase inhibi-tor 5-azacytidine were reported to differentiate into *** aim of the present study was to investigate theefficiency of a similar differentiation strategy in human mononuclear cells obtained from healthy bone marrow *** 1-3 passages,cultures were exposed for 24 h to 5-azacytidine（3μM）followed by 6 weeks of further *** treatment did not induce expression of myogenic marker MyoD or cardiac markers Nkx2.5 and GATA-4 and didnot yield beating cells during *** patch clamp experiments,approximately 10-15% of treated and untreatedcells exhibited L-type Ca2+ *** all cells showed outwardly rectifying K+currents of rapid or slow *** current amplitude at +60 mV doubled after 6 weeks of treatment compared with time-matched *** capacitance of treated cells was significantly larger than in controls 2 weeks after treatment and remained highafter 6 *** levels ofmRNAs for the K+channels Kv1.1,Kv1.5,Kv2.1,Kv4.3 and KCNMA1 and for theCa2+ channel Cav1.2 were not affected by *** with potassium channel blockers tetraethylammoniumand clofilium at concentrations shown previously to inhibit rapid or slowly activating K+currents of hMSC inhibitedproliferation of these *** results suggest that despite the absence of differentiation of hMSC into cardiomyocytes,treatment with 5-azacytidine caused profound changes in current density.

关键词： human mesenchymal stem cells 5-azacytidine cardiac differentiation outward K~+ currents

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18,X,Y aneuploidies and transmission electron microscopy studies in spermatozoa from five carriers of different reciprocal translocations

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Asian Journal of Andrology 2009年第3期11卷 325-332页

作者： Elena Moretti Nicola Antonio Pascarelli Valentina Giannerini Michela Geminiani cecilia Anichini Giulia Collodel Department of Biomedical Sciences Applied Biology Section University of Siena Siena 53100 Italy Department of Pediatrics Obstetrics and Reproductive Medicine University of Siena Siena 53100 Italy

We analysed ejaculated spermatozoa from five infertile men with different balanced reciprocal translocations to contribute to the study of meiotic segregation of chromosomes 18, X and Y and also to evaluate sperm morphology by transmission electron microscopy （TEM） analysis. Conventional lymphocyte karyotype analyses highlighted dif- ferent reciprocal balanced translocations： t（12; 13）, t（4;9）, t（X;8）, t（8; 10） and t（3; 16）. Semen analysis was performed by light and TEM. Fluorescence in situ hybridization was performed directly on sperm nuclei using centromeric probes for chromosomes 18, X and Y. The carriers of the balanced reciprocal translocations considered in the present study showed a very similar pattern of sperm pathologies： diffused presence of apoptosis and immaturity. All patients showed meiotic segregation derangements, highlighted by the presence of sperm diploidies and sex chromosome disomies particularly related to the failure of the first meiotic division. However, an increased incidence of chromosome 18 aneuploidy was detected in spermatozoa from t（X;8） and t（8;10） carriers. We have also reported values from sex chromosomes such as t（X;8）, although the X chromosome was involved in translocation. Since patients with reciprocal translocations and spermatogenetic impairment are candidates for intracytoplasmic sperm injection cycles, the study of sperm parameters, and particularly of the level of aneuploidy rates, would provide better information for couples at risk and would contribute to the data in the literature for a better understanding of the effects of chromosomal rearrangement on the whole meiotic process and, in particular, on chromosomes not involved in translocation.

关键词： electron microscopy fluorescence in situ hybridization altered karyotype spermatozoa reciprocal translocation

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China’s Noninterference Policy and Its Implications: the Case of China in Sub-Saharan Africa

China’s Noninterference Policy and Its Implications: the Ca...

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作者： cecilia Moipone Mokotjo（丽娅）山东大学

学位级别：硕士

中国经济在过去三十年里迅速发展备受世界关注,中国崛起的问题也引发了学者和国家政策制定者引人入胜的辩论和深入的研究。中国经济的崛起开启了中非关系的新时代,从而证明了中国和非洲国家之间的经济联系日益增多,这尤其表现在与撒哈... 详细信息

中国经济在过去三十年里迅速发展备受世界关注,中国崛起的问题也引发了学者和国家政策制定者引人入胜的辩论和深入的研究。中国经济的崛起开启了中非关系的新时代,从而证明了中国和非洲国家之间的经济联系日益增多,这尤其表现在与撒哈拉沙漠以南的国家之间。在过去的十年里,由于中国社会地位的提高,中非关系经历了一次充满活力的复兴。这些复兴主要表现在经济方面,包括中国对非洲基础设施投资和债务和解的增多,以及外交联系的密切。然而,这日益发展的关系也让许多国家产生中国对非洲国家帮助的真实意图的怀疑。尽管中国推动了非洲国家的经济发展以及帮助非洲国家克服了很多经济障碍,但这也被很多国家怀疑是在谋求对非洲国家的管控。虽然非洲国家热情地接受中国无附带条件的援助,西方国家却指出中国意在掠夺非洲自然资源来实现自我的发展。西方国家同时也指出,中国在保持“不干涉内政”政策的同时,忽视了对非洲国家的人权和社会公正以及政治民主方面的建设。中国只注重对非洲经济和财政方面的发展,这与西方在非洲的模式显然不同。中国和非洲的一些积极分子则认为,与西方在非洲失败的模式相比,中非之间的这种模式是最适合的。另一方面,在经常受到批评的同时,中国对非洲的发展援助政策还尚未显出很大成果。中非国家之间则认为,中国尊重非洲国家主权且帮助非洲经济发展,这就已经给非洲提供了和平解决内部矛盾的途径。最重要的是,本论文强调国际政治经济学,即政治和经济之间的相互影响。通过研究两者中其中一者对另一者的影响程度,来推论出中国的政策对非洲国家产生的直接和间接影响。当今的作家尖锐地指出：中国是经济导向型模式,而西方国家为政治导向型模式。而且,在经济方面,由于中国对撒哈拉沙漠以南国家自然资源的考虑,中国在撒哈拉沙漠以南的模式促进了非洲“荷兰病”现象的蔓延,即被称为“中国对非洲资源的掠夺”现象。因此,本论文评价了中国的“不干涉内政”政策是否真实,这种政策对非洲的发展有何启示意义。同时,本论文也探求关于中国与撒哈拉以南非洲国家的一些双边协定带来的机遇与挑战,以及这些协定以否是促进经济发展的最佳途径。同时,透过分析中国对撒哈拉以南非洲国家一系列的事务参与,本论文试图回答中国的“不干涉内政”政策是否需要改进。本论文承认撒哈拉以南非洲国家不断地得到了中国的利益,但也提倡两边政策之间的改进。第一章节简要介绍了在过去的三十年里中国的崛起以及充满活力的中非关系,这是为了给读者提供一个关于中非关系的历史走向。这个过程也有利于观察中国对非洲的政策是否受国际因素和国际力量变化的影响而改变。在观察中国对非洲的历史政策同时,本章节还通过提供不同学者关于中国“不干涉内政”政策和中非关系的学术观点,来也分析当今世界对中国“不干涉内政”政策及影响的看法。因为不同的观点也能消除偏见,从而提供一个全面的看法。第二章节阐述了“不干涉内政”政策的推论和其意义。尽管人们都把这个政策和中国关联起来,但这章节提供了不同国家以及一些国际机构对“不干涉内政”的看法。整个世界都承认,“不干涉内政”政策的原则最早是是来自于西方国家。然而,西方国家已经把该政策的思想提升了,认为在严重的人道主义情况出现时,可以对别的国家进行干涉,这被称为“非漠视”政策。因此,由于解释上的分歧,本章节探求中国对传统意义的“不干涉内政”原则严格坚守的理论根据。再者,本章节也分析非盟和中国对“不干涉内政”政策看法的相似点。因为中国受到过近百年耻辱的侵略,以及非洲的殖民历史经历,本章节通过中国在非洲的历史政策来分析当今的观点和政策。第三章是通过中国对撒哈拉以南非洲国家“不干涉内政”政策的实践,来进一步分析该政策。本章节通过列出中国的实践和“不干涉内政”政策相矛盾的例子,来探求中国对撒哈拉以南国家的行为举动是否始终坚持于该政策。通过分析历史上和当今中国对撒哈拉以南国家的政策,来观察其政策在本质上是否变化。此外,分析中国在联合国安全理事会的投票情况,也是一个分析中国国际立场的重要途径。最后,本章节也透过中国和所谓的“无赖国家”之间的关系及互动,来强调中国在撒哈拉以南国家的实际举动和“不干涉内政”政策之间的矛盾。第四章节试图综合地分析本论文前面所提及的中国在对撒哈拉以南国家的实际举动,以及分析这些举动对撒哈拉以南国家是否有直接和间接影响,这主要是通过评估经济、财政、社会经济和政治方面的结果来达成的。本章节是整个论文的总结性章节,最终阐述了中国对撒哈拉以南国家的参与是利大于弊,还是弊大于利,以及如何消除其弊端。此外,本章节也总结出中国的“不干涉内政”政策是否需要改正。最后,本章节也对所有的研究作总结,对中非关系的发展提出了一些大体的建议。

关键词：中国对非政策不干涉内政中非关系和平发展

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Dietary patterns and risk of cervical cancer: a case-control study in Uruguay

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Open Journal of Obstetrics and Gynecology 2011年第2期1卷 25-30页

作者： Eduardo De Stefani Gisele Acosta Hugo Deneo-Pellegrini Alvaro L. Ronco maría Mendilaharsu Gabriel Landó maría E. Luaces cecilia Silva 不详

In the time period 1996-2004, a case-control study on diet and cervical cancer was conducted at the National Cancer Institute in Uruguay. The study included 268 cases and 536 controls with non-neoplastic diseases. The foods and beverages in the food-frequency questionnaire were included in a factor analytic model. This method retained three factors which were labeled as the drinker, red meat, and prudent patterns. The model explained 60% of the variance. Whereas the red meat and drinker patterns were directly associated with the risk of cervical cancer (OR for red meat pattern 1.79, 95% CI 1.12-2.86), on the other hand, the prudent pattern was inversely associated with cervical cancer (OR 0.60, 95% CI 0.38-0.93). To our knowledge, this study was the first one using factor analysis in order to elucidate the role of the diet in relation with cervical cancer.

关键词： Dietary Patterns Cervical Cancer

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The antiplasmodial effect of the extracts and formulated capsules of Phyllanthus amarus on Plasmodium yoelii infection in mice

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Asian Pacific Journal of Tropical Medicine 2011年第4期4卷 283-287页

作者： Tolulope O Ajala cecilia I Igwilo Ibrahim A Oreagba Oluwatoyin A Odeku Department of Pharmaceutics & Pharmaceutical Technology Faculty of PharmacyOlabisi Onabanjo University Department of Pharmaceutics and Pharmaceutical Technology Faculty of PharmacyUniversity of Lagos Department of Pharmacology College of MedicineUniversity of Lagos Department of Pharmaceutics and Industrial Pharmacy Faculty of PharmacyUniversity of Ibadan

Objective:To investigate the antiplasmodial activity of the extracts of Phyllanthus amarus(P. amarus) on Plasmodium yoelii(***)(a resistant malaria parasite strain used in animal stuthes) infection in ***:The aqueous and ethanol extracts of the whole plant of Phyllanthus amarus was administered to Swiss albino mice at doses of 200 mg/kg/day,400 mg/ kg/day,800 mg/kg/day and 1 600 mg/kg/day and the prophylactic and chemotherapeutic effect of the extracts against *** infection in mice was investigated and compared with those of standard antimalaria drugs used in the treatment of malaria parasite *** toxicity test was carried out in mice to determine the safety of the plant extract when administered orally. Results:The results showed that the extracts demonstrated a dose-dependent prophylactic and chemotherapeutic activity with the aqueous extracts showing slightly higher effect than the ethanol *** antiplasmodial effects of the extracts were comparable to the standard prophylactic and chemotherapeutic drugs used in chloroquine resistant Plasmodium infection although the activity depended on the dose of the extract *** extracts showed prophylactic effect by significantly delaying the onset of infection with the suppression of 79% at a dose of 1 600 mg/kg/***:The results obtained indicate that the extracts of the whole plant of *** possess repository and chemotherapeutic effects against resistant strains of *** in Swiss albino *** findings justify the use of the extract of *** in traditional medicine practice,for the treatment of malaria infections.

关键词： Antiplasmodial activity Phyllanthus amarus Plasmodium yoelli Artesunate/amodiaquine Pyrimethamine

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Dynamics of populations with two sexes

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International Journal of Biomathematics 2015年第4期8卷 127-144页

作者： M. cecilia Perez E. Adriana Saavedra mariano A. Ferrari Facultad de Ingenieria Universidad Nacional de la Patagonia San Juan Bosco Esquel Chubut Argentina Facultad de Ingenieria Universidad Nacional de la Patagonia San Juan Bosco Trelew Chubut Argentina Facultad de Ingenierla Universidad Nacional de la Patagonia San Juan Bosco Puerto Madryn Chubut Argentina Centro Nacional Patagdnico CONICET Puerto Madryn Chubut Argentina

A mathematical model is presented in order to describe the dynamics of polygamous populations, bearing in mind single individuals of both sexes and the development of reproductive groups. In this context, the description leads us to consider positive homogeneous dynamical systems, establishing conditions for the stationary state existence and its local stability. A fourth pre-reproductive stage was considered, i.e. males and females spend part of their lives before being in condition to reproduce, as a first step to consider more general models. Finally, we parametrized the proposed model using southern elephant seal data, to analyze the direct applicability to a real population.

关键词： Dynamical systems two-sex model mating system local stability.

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