检索结果-南通市图书馆

诗刊 2024年第7期 168-174页

作者： [墨西哥]罗伯托·阿库尼亚范童心(译) 墨西哥国立自治大学不详

Research foresight in bridging open science and open innovation:Overview based on the complex thinking paradigm

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Innovation Studies 2024年第1期8卷 59-75页

作者： Jorge Sanabria-Z marco cruz-Sandoval Athziri Moreno-Romo Sofía Bosch-Gómez maría Soledad Ramírez-Montoya Institute for the Future of Education Tecnologico de MonterreyZapopan45201Mexico central Bohemian Innovation center(SIc) PragueCzech Republic The Burnes center for Social change Northeastern UniversityBostonMA02115USA Institute for the Future of Education Tecnologico de MonterreyMonterrey64700Mexico

Open innovation benefits from access to cutting-edge discoveries to increase their transformation into tangible applications for the benefit of *** research quality has been proposed as a primary objective of open science by the United Nations,to increase science reproducibility,impact,and trust,leading to robust decision-making and ***,opening access to data and processes is insufficient for researchers to achieve open innovation in the context of globalization,for example,by gathering insights from external and internal *** the appropriate mindset to manage complexity and generate synergy among researchers in academia,industry,and the government is essential to catalyze knowledge and transform it into relevant innovations for *** gain insights into the roles and challenges of researchers aiming to bridge the gap between open science and open innovation,a decade-plus Mapping Literature Review was conducted based on the complex thinking *** thinking allows for novel connections of the information collected through open science and open innovation,considering different forms of engaging with alternative means of knowledge creation that may promote innovative and critical *** findings revealed:a)broad positioning of the terms in the European Union;b)open access and open data as current driving themes;c)a constant trade-off between the terms“open data”and“information protection”;d)lack of studies on researchers’complex thinking to help them manage openness;e)absence of the environmental helix in the initiatives;and(f)challenges in innovative communication and collaborative practices among public and private ***,we identified an opportunity to develop researchers’complex thinking such that the openness of information becomes a shared responsibility among partners across multiple *** shared responsibility can have methodological implications that permeate how open science and ope

关键词： Open innovation Open science complex thinking Ecosystems Research enhancement Educational innovation Higher education

Experimental and computational study of smoke dynamics from multiple fire sources inside a large-volume building

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Building Simulation 2021年第4期14卷 1147-1161页

作者： Gabriele Vigne Wojciech Węgrzyński Alexis cantizano Pablo Ayala Guillermo Rein cándido gutiérrez-Montes Fluid Dynamics Division of the Department of Mining and Mechanical Engineering Universidad de JaénJaénSpain Institute for Research in Technology ICAIUniversidad Pontificia ComillasMadridSpain Building Research Institute(ITB) WarsawPoland Imperial college London LondonUK JVVA Fire&Risk MadridSpain

Fire in large-volume buildings poses separate and distinct challenges from compartmented *** particular,the risk it poses on life safety is mostly due to the smoke it produces,its effects on the evacuation process,and how it can affect the firefighters when they approach the building to fight the fire and rescue the *** is why smoke control in large-volume enclosures is of utter importance for life safety,property protection and business *** research presents an experimental and numerical study of the smoke dynamics from four fire sources(combined heat release rate of 5.2 MW)with different ignition times and under transient ventilation conditions,inside a 20 m high cubic *** measurements in the plume and close to the walls have been recorded using 59 *** data was used in the determination of the smoke layer interface height,with the least-square and the N-Percent *** show that significantly worse conditions are induced by multiple sources than those in a single fire of equal *** results have been obtained using the computational fluid dynamics code FDS(Fire Dynamics Simulator,v6.7.1).The comparison shows that in the far field the temperature predictions are accurate inside the smoke layer(10 m and 15 m)with discrepancies lower than 10%,whereas higher significant discrepancies were observed at the smoke layer interface,i.e.5 m high,with discrepancies up to 20%.Furthermore,a grid analysis has been performed showing that grid resolutions,D*/δ,based on the global HRR of the fire might be sufficient to predict the fire induced conditions far from the *** analysis confirmed the applicability of FDS to the assessment of the smoke dynamics under complex fire conditions away from ***,the present work shows the importance of considering fires with multiple sources due to the faster smoke production compared with single fires.

关键词： experiments simulation fire buildings FDS cFD

Gas-phase electrocatalytic conversion of cO_2 to chemicals on sputtered cu and cu–c catalysts electrodes

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Energy chemistry 2019年第4期28卷 46-53页

作者： N.gutiérrez-Guerra J.A.González J.c.Serrano-ruiz E.López-Fernández J.L.Valverde A.de Lucas-consuegra Departamento de Ingeniería Química Facultad de Ciencias y Tecnologías Químicas Universidad de Castilla-La Mancha Instituto Regional de Investigación científica Aplicada (IRIcA) and Departamento de Física Aplicada Universidad de Castilla-La Mancha Departamento de Ingeniería Universidad Loyola Andalucía

A novel gas-phase electrocatalytic cell containing a low-temperature proton exchange membrane(PEM)was developed to electrochemically convert cO_2into organic *** different cu-based cathode catalysts(cu and cu–c)were prepared by physical vapor deposition method(sputtering)and subsequently employed for the gas-phase electroreduction of cO_2at different temperatures(70–90°c).The prepared electrodes cu and cu–c were characterized by X-ray diffraction(XRD),X-ray photoemission spectroscopy(XPS)and scanning electron microscopy(SEM).As revealed,cu is partially oxidized on the surface of the samples and the cu and cu–c cathodic catalysts were comprised of a porous,continuous,and homogeneous film with nanocrystalline cu with a grain size of 16 and 8 nm,*** influence of the applied current and temperature on the electro-catalytic activity and selectivity of these materials was *** the two investigated electrodes,the pure cu catalyst film showed the highest cO_2specific electrocatalytic reduction rates and higher selectivity to methanol formation compared to the cu–c electrode,which was attributed to the higher particle size of the former and lower cu O/cu *** obtained results show potential interest for the possible use of electrical renewable energy for the transformation of cO_2into valuable products using low metal loading cu based electrodes(0.5 mg cu cm^(-2))prepared by sputtering.

关键词： cO_2 valorization Electro-reduction cu catalyst PEM Selectivity Methanol production

Hydrogeochemical Studies in Drought Scenarios: canelones, Uruguay case Study

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Journal of Geoscience and Environment Protection 2024年第5期12卷 188-217页

作者： Karina Pamoukaghlian Elena Alvareda mariano cáceres Rebeca Panzl marcelo Aboy Sofìa Da Rocha Pablo Gamazo maría Paula collazo Instituto de ciencias Geoló gicas Facultad de Ciencias Universidad de la Rep&#250blica Montevideo Uruguay Departamento del Agua Centro Universitario Regional Litoral Norte Universidad de la Rep&#250blica Salto Uruguay Á rea Toxicolog&#237a Departamento Estrella Campos Facultad de Qu&#237mica Universidad de la Rep&#250blica Montevideo Uruguay

The water scarcity in quality and quantity is becoming more noticeable and an urgent concern around the world. In Uruguay, these issues become exacerbated by the need to obtain drinking water in coastal areas, influenced by the climate change. Basic and structural geologies are strong conditioners in heterogeneous coastal aquifers. The objective of this study is to characterize the hydrochemistry of the fractured aquifers after having identified the main bearing fractures and the causes of aleatoreous water scarcity and quality problems, for hydric resources sustainable management. Identification of water bearing fracture, hydrogeochemical analysis and water quality evaluation are specific objectives. Some strategies were performed: 1) a base map in QGIS Software;2) fracture photointerpretation;3) geological correlation;4) statistical analysis of the background geochemistry data;5) ions analysis of strategically located wells. There were found water bearing fractures corresponding to 28 m3/h maximum flow rate for the NW-SE and 12 m3/h maximum flow rate for the NE-SW fracture direction, respectively. Besides, there could be a problem related to the high Sodium (Na) and chloride (cl) levels. In this respect, having previous data from 25 well samples, ions geochemical analysis has been carried out for 14 wells from costa Azul and surrounding to have a first approach about the possible cause for the high values of Na (max. 385 mg/L) and cl (max. 381 mg/L). The selected area for this study has a particular characteristic, because it corresponds to a heterogeneous fractured aquifer, which makes it difficult to catch water with enough flow rates and water quality to meet the population demand.

关键词： Water Bearing Fractures Hydrogeochemistry Water Quality Sustainable Management

Induced pluripotent stem cells from Huntington's disease patients:a promising approach to define and correct disease-related alterations

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2019年第5期14卷 769-770页

作者： Azra Fatima Ricardo gutiérrez-Garcia David Vilchez Institute for Genetics and cologne Excellence cluster for cellular Stress Responses in Aging-Associated Diseases(cEcAD) University of Cologne

Adult somatic cells such as skin or blood cells from either health donors or patients can be reprogrammed into induced pluripotent stem cells(iPScs).Given their unlimited self-renewal and differentiation capacities,iPScs are an invaluable resource to generate terminally differentiated ***,iPScs can facilitate the study of human diseases and drug screening,holding great promise for regenerative *** significant advantage of iPSc disease-modeling is that normal and mutant proteins are expressed at endogenous *** addition,subtle phenotypes and the effects of genetic background variations can be assessed by comparison between iPSc lines obtained from different patients and healthy donors as well as isogenic lines,in which disease-related mutations are corrected.

关键词： Adult somatic cells skin or blood cells Huntington’s disease patients

The Environmental Effects of Tourism Architecture on Island Ecosystem in cayo Guillermo, cuba

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Journal of Environmental Protection 2015年第9期6卷 1057-1065页

作者： Lourdes ruiz gutiérrez International University of Ecuador Quito Ecuador

The objective of this study is to determine the main adverse impacts that may be caused by tourism architecture upon island ecosystems consisting of small islands or islets and to propose an architectural and landscape design with a focus on the environmental sustainability of the same. A study of projects was undertaken in cayo Guillermo, located to the north of ciego de Avila in cuba using methods of life-cycle assessment of buildings, matrix methods of the activities that caused severe environmental impact and statistical processing through multivariate analysis. conclusions were reached on the need for designs that did not harm the ecosystems of islands with high ecological fragility. It has been determined that suitable construction intervention would decrease the negative impact and would allow the natural resources of these valuable ecosystems that are the basis for responsible sun and sand tourism to be preserved.

关键词： Environmental Effects Architecture Tourism Island Ecosystem

Impact Assessment of Tourism construction in cuba

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Building construction and Planning Research 2015年第1期3卷 10-17页

作者： Lourdes ruiz gutiérrez International University of Ecuador Quito Ecuador

This paper discusses a methodology for the environmental assessment of tourist facilities located in cuban coastal zones in which the general aspects of the process are discussed, defined, and characterized, and examines the main processes that occur as a result of the negative impacts of construction activities. It establishes the theoretical conceptual framework underlying the research and includes a detailed analysis and processing of a sample of tourism projects located in coastal ecosystems. The methodology is complemented by results that include proposed strategic lines of action and a plan for managing negative environmental impacts throughout the life cycle of tourist facilities through prevention, correction and mitigation measures. It ends with conclusions and recommendations to guide tourism development toward environmental sustainability.

关键词： Environmental Impact Tourist Facilities coastal Ecosystems construction

Medical plant extracts and natural compounds with a hepatoprotective effect against damage caused by antitubercular drugs: A review

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Asian Pacific Journal of Tropical Medicine 2016年第12期9卷 1116-1125页

作者： maría Adelina Jiménez-Arellanes Gabriel Alfonso gutiérrez-Rebolledo mariana Meckes-Fischer Rosalba León-Díaz Unidad de Investigación Médica en Farmacología.UMAE Hospital de Especialidades Centro Médico Nacional-Siglo XXI.Instituto Mexicano del Seguro Social

Drug-induced liver injury encompasses a spectrum of diseases ranging from mild biochemical abnormalities to acute liver failure; example of this scenery is hepatotoxicity caused by the first-line antituberculous drugs isoniazid, rifampin and pyrazinamide, which are basic for treatment of drug-sensible and drug-resistant tuberculosis. In the search for pharmacological alternatives to prevent liver damage, antitubercular drugs have been the subject of numerous studies and published reviews, a great majority of them carried out by Asian countries. At the same time, hepatoprotectors from plant source are now emerging as a possible alternative to counteract the toxic effects of these therapeutic agents. The present review aims to highlight the most recent studies on the subject, based information published in scientific databases such as Scopus and Pub Med.

关键词： Medicinal plants Hepatoprotective effect Antitubercular drugs-induced hepatotoxicity Natural compounds

Ursane derivatives isolated from leaves of Hylocereus undatus inhibit glycation at multiple stages

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

chinese Journal of Natural Medicines 2018年第11期16卷 856-865页

作者： ROSA marTHA Pérez-gutiérrez SUSANA GABRIELA Enriquez-Alvirde Research Laboratory of Natural Products School of Chemical Engineering and Extractive Industries National Polytechnic Institute

The present study was designed to evaluate the therapeutic potential of bioactive compounds from chloroform extract of the leaves of Hylocereus undatus in the formation of advanced glycation end products(AGEs) in vitro. Bioactivity-guided fractionation of chloroform extract from Hylocereus undatus afforded two novel 12-ursen-type triterpenes, 3β, 16α, 23-trihydroxy-urs-12-en-28-oic acid(1) and 3β, 6β, 19α, 22α-tetrahydroxy-urs-12-en-28-oic acid(2), as well as four known triterpenes 2α, 3β, 23-tetrahydroxy-urs-11-en-28-oic acid(3), 3β-acetoxy-28-hydroxyolean-12-ene(4), 3β, 16α-dihidroxyolean-12-ene(5) and 3β-acetoxy-olean-12-ene(6). Our results revealed that triterpenes 1–3 were able to inhibit the formation of AGEs in all tested assays. The data indicated that the triterpenes had inhibitory activity at the múltiple stages of glycation and that there might be a high potential for decreasing protein oxidation and protein glycation that can enhance glycative stress in diabetic complications.

关键词： Hylocereus undatus Advanced glycation end product Triterpenes