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Hydrocarbon generation from lacustrine shales with retained oil during thermal maturation

Petroleum Science 2020年第6期17卷 1478-1490页

作者： Xin-He Shao Xiong-Qi Pang mao-wen li Zhi-Ming li Yi Zhao State Key Laboratory of Petroleum Resources and Prospecting China University of PetroleumBeijing 102249China College of Geosciences China University of PetroleumBeijing 102249China State Key Laboratory of Shale Oil and Shale Gas Resources and Eff ective Development SINOPEC Petroleum Exploration and Production Research InstituteBeijing 100083China SINOPEC Key Laboratory of Petroleum Accumulation Mechanisms Wuxi Institute of Petroleum GeologyWuxi 214126JiangsuChina

Thermal maturation in the shale oil/gas system is inherently complex due to the competitive interplays between hydrocarbon generation and retention *** study hydrocarbon generation characteristics from shales within different stages of thermal maturation under the influence of retained oil,we performed Micro-Scale Sealed Vessels(MSSV)pyrolysis on a set of artificially matured lacustrine shale s amples from the Shahejie Formation in the Dongpu Depression in Bohai B ay Basin,*** results show that hydrocarbon yields of shale samples with or without retained oil at various thermal maturities follow different evolution *** components(C15+)in samples crack at high temperatures and generally follow a sequence,where they first transform into C6-14 then to C2-5 and *** accounts for most of the gaseous products at high temperatures in all samples,with different *** cracking of C2-5 is the main methane-generating process in samples with retained oil,whereas the source of methane in samples without retained oil is *** the studied shales,retained oils at early-mature stage retard the transformation of liquid to gaseous hydrocarbon and prompt the cracking of C2-5 to C1 to some *** reaction related to gypsum in the studied samples is the primary reason that can explain the loss of hydrocarbon yields,especially at high *** addition,transformation of volatile hydrocarbons to gas and coke also accounts for the loss of generated hydrocarbon,as a secondary factor.

关键词： MSSV pyrolysis Hydrocarbon generation Lacustrine shales Thermal maturation Retained oil

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Establishment of multiplexed,microsphere-based flow cytometric assay for multiple human tumor markers

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Acta Pharmacologica Sinica 2007年第12期28卷 2011-2018页

作者： Kai SUN,Qian WANG~2,Xiao-hui HUANG,mao-chuan ZHEN,wen li,Long-juan ZHANGDepartment of Hepatobiliary Surgery,the First Affiliated Hospital of Sun Yat-Sen University,Guangzhou 510080,China Department of Hepatobiliary Surgery the First Affiliated Hospital of Sun Yat-Sen University Guangzhou China

Aim:The multiplexed,microsphere-based flow cytometric assay (MFCA) for mul-tiple human tumor markers was established for the early screening and detectionof suspected cancer ***:Covalent coupling of capture antibodiesdirected against their respective tumor markers to fluorescent microspheres wasperformed by following the protocols recommended by a commercial corporationwith some *** coupling efficiency and cross-reactivity were iden-tified by the Luminex 100 system and associated *** standard curvewas constructed by using serial dilution of recombinant tumor marker standardsand was validated by comparison with EliSA for quantifying the tumor markers inserum ***:The identifications revealed that the coupling proce-dures were successful without non-specific cross-reactivity and the standardcurve was highly ***,it was necessary to ensure the quality con-trol of the coupling process since slight variations in the coupling procedurescould profoundly affect the density of capture reagents coupled to themicrospheres and consequently adversely affect the assay *** additionto its multi-analyte capability,the MFCA system had definite advantages,such ashigher reproducibility,greater dynamic range of measurement,and considerablyless preparation time and labor over the conventional"gold standard",which wasthe ***:The successful establishment of the MFCA system forthe simultaneous detection of multiple tumor markers will provide the foundationfor the further study of clinical applications.

关键词： fluorescent microsphere microsphere-based flow cytometric assay tumor marker

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固液混合发动机燃面退移规律辩识方法

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推进技术 2006年第6期27卷 481-483,509页

作者：杨威许敏毛成立毛励文上海新力动力设备研究所上海200125

为了以尽可能少的试验对固液混合发动机的燃面退移规律进行辨识,采用在一发试验中适当调节工作参数的方式,并结合瞬时燃面退移速率求解方法,总结出了一套固液混合发动机燃面退移规律辨识方法进行了试验验证,结果表明:采用二维药型的固... 详细信息

为了以尽可能少的试验对固液混合发动机的燃面退移规律进行辨识,采用在一发试验中适当调节工作参数的方式,并结合瞬时燃面退移速率求解方法,总结出了一套固液混合发动机燃面退移规律辨识方法进行了试验验证,结果表明:采用二维药型的固液混合发动机,通过一发试验即可较准确地掌握其燃面退移规律,还可应用于其它同种类型的固液混合发动机内弹道性能预测。

关键词：固液混合发动机退移速率内弹道性能预测

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Wave effect of gravitational waves intersected with a microlens field Ⅱ:An adaptive hierarchical tree algorithm and population study

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 241-254页

作者： Xikai Shan Guoliang li Xuechun Chen wen Zhao Bin Hu Shude mao Department of Astronomy Tsinghua University Purple Mountain Observatory Chinese Academy of Sciences Institute for Frontier in Astronomy and Astrophysics Beijing Normal University School of Physics and Astronomy Beijing Normal University School of Astronomy and Space Science University of Science and Technology of China CAS Key Laboratory for Researches in Galaxies and Cosmology Department of Astronomy University of Science and Technology of ChinaChinese Academy of Sciences

The gravitational lensing wave effect generated by a microlensing field embedded in a lens galaxy is an inevitable phenomenon in strong lensed gravitational waves （SLGWs）.This effect presents both challenges and opportunities for the detection and application of ***,investigating this wave effect requires computing a complete diffraction integral over each microlens in the *** is extremely time-consuming due to the large number of microlenses （10～3-10～6）.Therefore,simply adding all the microlenses is ***,the complexity of the time delay surface makes the lens plane resolution a crucial factor in controlling numerical *** this paper,we propose a trapezoid approximation-based adaptive hierarchical tree algorithm to meet the challenges of calculation speed and *** find that this algorithm accelerates the calculation by four orders of magnitude compared to the simple adding method and is one order of magnitude faster than the fixed hierarchical tree algorithm proposed for electromagnetic *** importantly,our algorithm ensures controllable numerical errors,increasing confidence in the *** with our previous work （***.66,239511,2023）,this paper addresses all numerical issues,including integral convergence,precision,and computational time1).Finally,we conducted a population study on the microlensing wave effect of SLGWs using this algorithm and found that the microlensing wave effect cannot be ignored,especially for Type II SLGWs （from saddle position of the time delay surface） due to their intrinsic geometric structures and their typical intersection with a denser microlensing ***,more than 33%（11%） of SLGWs have a mismatch larger than 1%（3%） compared to the unlensed ***,we found that the mismatch between signal pairs in a doubly imaged GW is generally larger than 10-3,and 61%（25%） of signal pairs have a mismatch larger than 1%（3%）.Therefo

关键词： gravitational lensing diffractional integral algorithm gravitational wave

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轮轨系统的现状与展望

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交通运输工程学报 2022年第1期22卷 42-57页

作者：沈钢毛鑫毛文力董强强尹相琴同济大学铁道与城市轨道交通研究院上海201804 中国铁路上海局集团有限公司上海大型养路机械运用检修段上海200439 中国铁路上海局集团有限公司上海动车段上海201812 云南汇通成铁路设备有限公司云南昆明650220

总结了现有传统钢轮钢轨式轮轨系统的工程问题、研究现状和工程处理方法;分析了钢轨波磨和车轮不圆的形成和发展机理,对困扰高铁的踏面凹磨问题提出了创新性治理设想;拟通过轮轨系统的廓形设计-磨损评价-磨损治理的系统化革新思路,获得... 详细信息

总结了现有传统钢轮钢轨式轮轨系统的工程问题、研究现状和工程处理方法;分析了钢轨波磨和车轮不圆的形成和发展机理,对困扰高铁的踏面凹磨问题提出了创新性治理设想;拟通过轮轨系统的廓形设计-磨损评价-磨损治理的系统化革新思路,获得既安全又经济的线路条件个性最优化方案;总结和展望了目前轮轨系统的打磨和镟轮,讨论了轮轨系统的检测方法;提出了避免过度检测的新思路,并预测了轮轨系统的未来发展前景。分析结果表明:钢轨波磨和车轮失圆的机理都出于轮轨系统的参激振动与切向轮轨磨损的耦合,在交变正压力和切向磨损同相位作用下,使凸起区域的磨损低于凹下区域的磨损;高铁的凹磨问题是轮轨在高速直线上和超大半径曲线上,轮轨处于非常微小的横向扰动,又在非常平顺的线路下发生镶嵌磨损,即轮轨接触部分廓形发生相互拷贝式磨损;低速城轨系统轮缘侧面磨损是由于在较小曲线半径上运行时,在较大的横向蠕滑作用下引起轮缘的导向作用而为,其踏面不易发生凹磨;钢轨和道岔的各种病害与轴重和冲击载荷有关,其疲劳破坏以局部应力过大下的低周疲劳为主;随着车辆速度和轴重的提高,轮轨系统仅在车辆侧和轨道侧进行优化已达到极限,只有相互联合优化才能深入发掘潜力,继续维持轮轨交通的应用价值。

关键词：轨道交通轮轨系统轮轨维护踏面/钢轨外形设计旋轮打磨

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刘建秋教授治疗特发性肺纤维化经验

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中华中医药杂志 2015年第9期30卷 3182-3184页

作者：毛文丽李竹英黑龙江中医药大学哈尔滨150040 黑龙江中医药大学附属第一医院哈尔滨150040

特发性肺纤维化的病因与发病机制尚未完全明确,刘建秋教授认为其主要病机为本虚标实,肺肾两虚为病之本,痰、瘀为病之标,并以此提出了"益气养阴、补肺健脾益肾、化痰祛瘀通络"的治则。以益气养阴、补肺健脾益肾为本,提高肺脏功能;以化痰... 详细信息

特发性肺纤维化的病因与发病机制尚未完全明确,刘建秋教授认为其主要病机为本虚标实,肺肾两虚为病之本,痰、瘀为病之标,并以此提出了"益气养阴、补肺健脾益肾、化痰祛瘀通络"的治则。以益气养阴、补肺健脾益肾为本,提高肺脏功能;以化痰祛瘀为助,改善局部病灶,临证时辨证施治,疗效甚佳。文章先从探讨特发性肺纤维化的病因病机入手,详述了刘建秋教授对此病的诊疗特点,并加1则典型病案予以阐述,总结了刘建秋教授治疗特发性肺纤维化的经验。

关键词：特发性肺纤维化刘建秋经验中医药

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浅谈计算机房环境条件对设备的影响

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浙江电力 2009年第B7期28卷 84-86页

作者：毛文利浙江省电力试验研究院杭州310014

计算机监控和信息机房使用了大量易受环境条件影响的电子元器件,这些设备对机房环境有严格的要求。通过对计算机监控和信息机房环境条件的测量,从温度、湿度、尘埃、振动、噪声、电磁干扰等几个方面,阐述了计算机监控和信息机房的环境... 详细信息

计算机监控和信息机房使用了大量易受环境条件影响的电子元器件,这些设备对机房环境有严格的要求。通过对计算机监控和信息机房环境条件的测量,从温度、湿度、尘埃、振动、噪声、电磁干扰等几个方面,阐述了计算机监控和信息机房的环境条件对设备的影响。

关键词：计算机监控信息机房环境条件设备影响

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桥梁钢护栏防撞性能有限元分析

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浙江交通职业技术学院学报 2011年第4期12卷 14-18页

作者：毛雯丽浙江工业大学杭州310014 浙江交通职业技术学院杭州311112

梁柱式钢护栏作为一种半刚性护栏,具有一定的刚性和柔性,能依靠护栏的弯曲变形和张拉力来抵抗车辆的碰撞。为研究桥梁钢护栏的防撞性能,本文采用ABAQUS有限元分析软件对桥梁梁柱式钢护栏进行静力碰撞分析,研究了碰撞速度一定时,不同碰... 详细信息

梁柱式钢护栏作为一种半刚性护栏,具有一定的刚性和柔性,能依靠护栏的弯曲变形和张拉力来抵抗车辆的碰撞。为研究桥梁钢护栏的防撞性能,本文采用ABAQUS有限元分析软件对桥梁梁柱式钢护栏进行静力碰撞分析,研究了碰撞速度一定时,不同碰撞角度对碰撞性能的影响,结果表明在初始碰撞速度80 km/h不变的情况下,随着碰撞角度的增大,护栏的最大应力和最大位移都将增大,从而使护栏提前进入塑性阶段而屈服。

关键词：桥梁钢护栏碰撞有限元 ABAQUS 碰撞角度

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电力系统常用油品中磨损金属测定方法的研究

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电力环境保护 2006年第2期22卷 57-60页

作者：毛文利浙江电力试验研究所浙江杭州310000

采用干、湿两种消解方法,进行了电力系统常用油品的消解方法研究,对消解后试液采用ICP/AES无机进样系统进行测定。通过对测定结果的统计、处理和汇总,以及方法精密度和准确度验证,最终得出了用直接燃烧灰化法代替ASTMD5708标准中的湿法... 详细信息

采用干、湿两种消解方法,进行了电力系统常用油品的消解方法研究,对消解后试液采用ICP/AES无机进样系统进行测定。通过对测定结果的统计、处理和汇总,以及方法精密度和准确度验证,最终得出了用直接燃烧灰化法代替ASTMD5708标准中的湿法消解来进行样品消解浓缩,使整个操作更为简便、省时。

关键词：油品磨损金属测定研究

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Real-world evidence on the efficacy and safety of vonoprazanamoxicillin dual therapy for Helicobacter pylori treatment in elderly patients

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World Journal of Gastroenterology 2025年第1期31卷 68-78页

作者： wen Gao Jing-wen li Hui Ye Xue-Zhi Zhang Jian-Xiang liu Hong Cheng Department of Gastroenterology Peking University First HospitalBeijing 100034China School of Medicine Tsinghua MedicineTsinghua UniversityBeijing 100034China Department of Traditional Chinese Medicine and Integrative Medicine Peking University First HospitalBeijing 100034China

BACKGROUND A dual therapy regimen containing amoxicillin is a common treatment option for the eradication of Helicobacter pylori(***).While substantial research supports the efficacy and safety of vonoprazan and amoxicillin(VA)dual therapy in the general population,there is still a lack of studies specifically focusing on its safety in elderly *** To evaluate efficacy and safety of VA dual therapy as first-line or rescue treatment for *** in elderly *** As a real-world retrospective study,data were collected from elderly patients aged 60 years and above who accepted VA dual therapy(vonoprazan 20 mg twice daily+amoxicillin 1000 mg thrice daily for 14 days)for *** eradication in the Department of Gastroenterology at Peking University First Hospital between June 2020 and January *** status was evaluated by^(13)C-urease breath test 6 weeks after *** adverse events(AEs)during treatment were *** In total,401 cases were ***-one cases were excluded due to loss to follow-up,lack of re-examination,or unwillingness to take *** total of 380 included cases comprised 250 who received VA dual therapy as first-line treatment and 130 who received VA dual therapy as rescue *** was successfully eradicated in 239 cases(95.6%)in the first-line treatment group and 116 cases(89.2%)in the rescue treatment *** overall incidence of AEs was 9.5%for both ***,9.2%of patients experienced an AE in the first-line treatment group and 10.0%in the rescue treatment *** patients discontinued treatment due to AE,with a discontinuation rate of 1.3%.No serious AE *** The VA dual therapy regimen as a first-line treatment and a rescue therapy was effective and safe for elderly patients aged 60 and older.

关键词： Helicobacter pylori Vonoprazan Amoxicillin Dual therapy Elderly

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