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Alcohol drinking triggered decrease of oxidative balance score is associated with high all-cause and cardiovascular mortality in hypertensive individuals: findings from NHANES 1999-2014

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Journal of geriatric cardiology : JGC 2024年第8期21卷 779-790页

作者： Yu-Jun Zhang Jing-Jing Song Jian-Hao Zhan Chu-Lin Zhou Ao Li mao-qi wang Ben-Jie Li Cong-Cong Ding Yi-Wei Zhang Zi-Heng Tan Zai-Hua Cheng Xiao Huang Department of Cardiology the Second Affiliated Hospital Jiangxi Medical College Nanchang University Nanchang China. Huankui Academy Nanchang University Nanchang China. School of Ophthalmology and Optometry of Nanchang University Nanchang China. The Second Clinical Medical College Nanchang University Nanchang China. Queen Mary School Nanchang University Nanchang China. The First Clinical Medical College Nanchang University Nanchang China. Department of Cardiovascular Medicine Huzhou First People's Hospital Zhejiang China.

BACKGROUND:Oxidative stress is closely associated with hypertensive outcomes. The oxidative balance score (OBS) measures oxidative stress exposure from dietary and lifestyle elements. The objective of this study was to investigate the association between OBS and mortality in hypertensive patients.METHODS:This study included 7823 hypertensive patients from the National Health and Nutrition Examination Survey (NHANES) 1999-2014. Several models, including Cox regression, restricted cubic splines (RCS), Kaplan‒Meier survival analysis, subgroup, and sensitivity analyses, were exploited to investigate the relationship between OBS and the risk of mortality.RESULTS:Controlling for all potential confounders, a significantly inverse association was observed between elevated OBS and all-cause [hazard ratio (HR) = 0.90, 95% CI: 0.85-0.95] and cardiovascular mortality (HR = 0.85, 95% CI: 0.75-0.95). With adjustment for covariates, significant associations between lifestyle OBS and mortality risks diminished, whereas associations between dietary OBS and these mortality risks remained robust (all-cause mortality: HR = 0.91, 95% CI: 0.86-0.96; cardiovascular mortality: HR = 0.85, 95% CI: 0.76-0.96). RCS demonstrated a linear relationship between OBS and all-cause and cardiovascular mortality risk ( = 0.088 and = 0.447, respectively). Kaplan‒Meier curves demonstrated that the mortality rate was lower with a high OBS ( < 0.001). The consistency of the association was demonstrated in subgroup and sensitivity analyses. RCS after stratification showed that among current drinkers, those with higher OBS had a lower risk of mortality compared with former or never drinkers.CONCLUSIONS:In hypertensive individuals, there was a negative association between OBS and all-cause and cardiovascular mortality. Encouraging hypertensive individuals, especially those currently drinking, to maintain high levels of OBS may be beneficial in improving their prognosis.

关键词： high finding Alcohol

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Alcohol drinking triggered decrease of oxidative balance score is associated with high all-cause and cardiovascular mortality in hypertensive individuals: findings from NHANES 1999–2014

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Journal of Geriatric Cardiology 2024年第08期 779-790页

作者： Yu-Jun ZHANG Jing-Jing SONG Jian-Hao ZHAN Chu-Lin ZHOU Ao LI mao-qi wang Ben-Jie LI Cong-Cong DING Yi-Wei ZHANG Zi-Heng TAN Zai-Hua CHENG Xiao HUANG Department of Cardiology the Second Affiliated Hospital Jiangxi Medical College Nanchang University Huankui Academy Nanchang University School of Ophthalmology and Optometry of Nanchang University The Second Clinical Medical College Nanchang University Queen Mary School Nanchang University The First Clinical Medical College Nanchang University Department of Cardiovascular Medicine Huzhou First People's Hospital

BACKGROUND Oxidative stress is closely associated with hypertensive *** oxidative balance score （OBS） measures oxidative stress exposure from dietary and lifestyle *** objective of this study was to investigate the association between OBS and mortality in hypertensive *** This study included 7823 hypertensive patients from the National Health and Nutrition Examination Survey （NHA-NES） *** models,including Cox regression,restricted cubic splines （RCS）,Kaplan-Meier survival analysis,subgroup,and sensitivity analyses,were exploited to investigate the relationship between OBS and the risk of *** Controlling for all potential confounders,a significantly inverse association was observed between elevated OBS and all-cause[hazard ratio （HR）=0.90,95%CI:0.85-0.95]and cardiovascular mortality （HR=0.85,95%CI:0.75-0.95）.With adjustment for covariates,significant associations between lifestyle OBS and mortality risks diminished,whereas associations between dietary OBS and these mortality risks remained robust （all-cause mortality:HR=0.91,95%CI:0.86-0.96;cardiovascular mortality:HR=0.85,95%CI:0.76-0.96）.RCS demonstrated a linear relationship between OBS and all-cause and cardiovascular mortality risk (Pnonlinear=0.088 and Pnonlinear=0.447,respectively).Kaplan-Meier curves demonstrated that the mortality rate was lower with a high OBS （P<0.001）.The consistency of the association was demonstrated in subgroup and sensitivity *** after stratification showed that among current drinkers,those with higher OBS had a lower risk of mortality compared with former or never *** In hypertensive individuals,there was a negative association between OBS and all-cause and cardiovascular *** hypertensive individuals,especially those currently drinking,to maintain high levels of OBS may be beneficial in improving their prognosis.

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Lithological Facies Classification Using Attention-Based Gated Recurrent Unit

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Tsinghua Science and Technology 2024年第4期29卷 1206-1218页

作者： Yuwen Liu Yulan Zhang Xingyuan mao Xucheng Zhou Jingwen Chang Wenwei wang Pan wang Lianyong qi College of Computer Science and Technology China University of Petroleum(East China)Qingdao 266580China Shandong Provincial University Laboratory for Protected Horticulture Weifang University of Science and TechnologyShouguang 262700China School of Mechanical Electrical and Information EngineeringShandong UniversityWeihai 264209China Shandong Provincial Key Laboratory of Network Based Intelligent Computing University of JinanJinan 250022China School of Modern Posts Nanjing University of Posts and TelecommunicationsNanjing 210023China

Lithological facies classification is a pivotal task in petroleum geology, underpinning reservoir characterization and influencing decision-making in exploration and production operations. Traditional classification methods, such as support vector machines and Gaussian process classifiers, often struggle with the complexity and nonlinearity of geological data, leading to suboptimal performance. Moreover, numerous prevalent approaches fail to adequately consider the inherent dependencies in the sequence of measurements from adjacent depths in a well. A novel approach leveraging an attention-based gated recurrent unit (AGRU) model is introduced in this paper to address these challenges. The AGRU model excels by exploiting the sequential nature of well-log data and capturing long-range dependencies through an attention mechanism. This model enables a flexible and context-dependent weighting of different parts of the sequence, enhancing the discernment of key features for classification. The proposed method was validated on two publicly available datasets. Results demonstrate a considerably improvement over traditional methods. Specifically, the AGRU model achieved superior performance metrics considering precision, recall, and F1-score.

关键词： attention mechanism facies classification GRU MLP(multilayer perceptron)

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BoMyrosinase plays an essential role in sulforaphane accumulation in response to selenite treatment in broccoli

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Horticultural Plant Journal 2024年第2期10卷 488-502页

作者： qiuyun Wu qi Wu Yuxiao Tian Chunyan Zhou Shuxiang mao Junwei wang Ke Huang College of Horticulture Hunan Agricultural UniversityChangshaHunan 410128China Engineering Research Center for Horticultural Crop Germplasm Creation and New Variety Breeding Ministry of EducationChangshaHunan 410128China Key Laboratory for Vegetable Biology of Hunan Province ChangshaHunan 410128China Key Laboratory for Evaluation and Utilization of Gene Resources of Horticultural Crops Ministry of Agriculture and Rural Affairs of ChinaChangshaHunan 410128China

Sulforaphane, a naturally specialized metabolite, plays significant roles in human disease prevention and plant defense. Myrosinase(MY) is a key gene responsible for the catalysis of sulforaphane formation, but the molecular mechanisms through which MY regulates sulforaphane biosynthesis in plants remains largely unknown. Here, we discovered that the change of sulforaphane content in broccoli sprouts caused by exogenous selenite treatments is positively related to BoMY expression. BoMY overexpression in the Arabidopsis thaliana tgg1 mutants could dramatically increase myrosinase activity and sulforaphane content in the rosette leaves of 35S::BoMY/tgg1 and rescue its ***, an obvious increase of myrosinase activity and sulforaphane content was displayed in transgenic BoMY-overexpressed broccoli *** addition, a 2 033 bp promoter fragment of BoMY was isolated. Yeast one-hybrid(Y1H) library screening experiment uncovered that one bHLH transcription factor, BoFAMA, could directly bind to BoMY promoter to activate its expression, which was further evidenced by Y1H assay and dual-luciferase reporter assay. BoFAMA is a selenite-responsive transcription factor that is highly expressed in broccoli leaves;its protein is solely localized to nucleus. Additionally, genetic evidence suggested that the knockdown of FAMA gene in Arabidopsis thaliana could significantly decrease sulforaphane yield by inhibiting the expression of myrosinase genes. Interestingly, exogenous selenite supply could partially restore the low level of sulforaphane content in transgenic Arabidopsis FAMA-silencing plants. Our findings uncover a novel function of FAMAMY module in the regulation of selenite-mediated sulforaphane synthesis and provide a new insights into the molecular mechanism by which selenite regulates the accumulation of sulforaphane in plants.

关键词： Brassica oleracea var.italica Myrosinase BoMY Sulforaphane Selenite treatment

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On a Flexible Loan Repayment Method Depending on Borrower's Asset with an Early Termination Clause

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Acta Mathematicae Applicatae Sinica 2024年第2期40卷 557-567页

作者： Jin LIANG Jia-qi mao Zhao-ya LIU School of Mathematical Sciences Tongji UniversityShanghai 200092China

Aiming at the problem that the asset’s fluctuation influences the borrower’s repayment ability,a loan with a new and flexible repayment method is designed,which depends on the asset value of the *** repayment method can reduce the loan default probability,but it causes the uncertainty of the pay off *** the repayment term is related to the regular repayment amount in this method,a boundary for the regular repayment amount is set up in order to avoid too long repayment *** will balance the benefit of borrowers and lenders and improve the applicability of this *** establishing a mathematical model of the residual value of the loan,this model can be transformed into an initial-boundary problem of a partial differential *** analytic solution and the expected time to pay off the loan are ***,numerical analysis are shown.

关键词： flexible repayment method repayment ratio early termination clause expected pay off time

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In Situ Atomic Reconstruction Engineering Modulating Graphene-Like MXene-Based Multifunctional Electromagnetic Devices Covering Multi-Spectrum

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Nano-Micro Letters 2024年第9期16卷 247-261页

作者： Ting‑Ting Liu qi Zheng Wen‑qiang Cao Yu‑Ze wang Min Zhang Quan‑Liang Zhao mao‑Sheng Cao School of Materials Science and Engineering Beijing Institute of TechnologyBeijing 100081People’s Republic of China Department of Physics Beijing Technology and Business UniversityBeijing 100048People’s Republic of China School of Mechanical and Materials Engineering North China University of TechnologyBeijing 100144People’s Republic of China

With the diversified development of big data,detection and precision guidance technologies,electromagnetic(EM)functional materials and devices serving multiple spectrums have become a hot *** the multispectral response of materials is a challenging and meaningful scientific *** this study,MXene/TiO_(2)hybrids with tunable conduction loss and polarization relaxation are fabricated by in situ atomic reconstruction *** importantly,MXene/TiO_(2)hybrids exhibit adjustable spectral responses in the GHz,infrared and visible spectrums,and several EM devices are constructed based on *** antenna array provides excellent EM energy harvesting in multiple microwave bands,with|S11|up to−63.2 dB,and can be tuned by the degree of *** ultra-wideband bandpass filter realizes a passband of about 5.4 GHz and effectively suppresses the transmission of EM signals in the *** infrared stealth device has an emissivity of less than 0.2 in the infrared spectrum at wavelengths of 6-14μ*** work can provide new inspiration for the design and development of multifunctional,multi-spectrum EM devices.

关键词： Graphene-like MXene hybrids Multi-spectral response Multi-function antenna Ultra-wideband bandpass filter Electromagnetic device

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A nano-sheet graphene-based enhanced thermal radiation composite for passive heat dissipation from vehicle batteries

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Nano Materials Science 2024年第4期6卷 443-455页

作者： Ji-Xiang wang Christopher Salmean Jiaxin Li Chaojie Lei Jun Li Mingliang Zhong Bo qi Yufeng mao Hebei Key Laboratory of Man-machine Environmental Thermal Control Technology and Equipment Hebei Vocational University of Technology and Engineering College of Electrical Energy and Power EngineeringYangzhou University Department of Mechanical and Aerospace Engineering The Hong Kong University of Science and Technology Taizhou Wavexploration Energy Ltd. Department of Electrical and Computer Engineering University of Toronto China Academy of Launch Vehicle Technology Beijing Sino-Spark Technology Co. Ltd. School of Environmental Science and Engineering Suzhou University of Science and Technology Institute of Optics and Electronics Chinese Academy of Sciences National Key Laboratory of Optical Field Manipulation Science and Technology Chinese Academy of Sciences

In response to thermal runaway(TR) of electric vehicles, recent attention has been focused on mitigation strategies such as efficient heat dredging in battery thermal management. Thermal management with particular focus on battery cooling has been becoming increasingly significant. TR usually happened when an electric vehicle is unpowered and charged. In this state, traditional active battery cooling schemes are disabled, which can easily lead to dangerous incidents due to loss of cooling ability, and advanced passive cooling strategies are therefore gaining importance. Herein, we developed an enhanced thermal radiation material, consisting of ～1 μm thick multilayered nano-sheet graphene film coated upon the heat dissipation surface, thereby enhancing thermal radiation in the nanoscale. The surface was characterized on the nanoscale, and tested in a battery-cooling *** found that the graphene-based coating's spectral emissivity is between 91 % and 95 % in the mid-infrared region, and thermal experiments consequently illustrated that graphene-based radiative cooling yielded up to15.1 % temperature reduction when compared to the uncoated analogue. Using the novel graphene surface to augment a heat pipe, the temperature reduction can be further enlarged to 25.6 %. The new material may contribute to transportation safety, global warming mitigation and carbon neutralization.

关键词： Battery thermal management Nano-sheet graphene Functional material Passive cooling Thermal radiation

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Optimization Design of the Multi-Layer Cross-Sectional Layout of An Umbilical Based on the GA-GLM

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China Ocean Engineering 2024年第2期38卷 247-254页

作者： YANG Zhi-xun YIN Xu FAN Zhi-rui YAN Jun LU Yu-cheng SU qi mao Yandong wang Hua-lin Institute of marine machinery College of Mechanical and Electrical EngineeringHarbin Engineering UniversityHarbin 150001China State Key Laboratory of Structural Analysis Optimization and CAE Software for Industrial EquipmentDepartment of Engineering MechanicsDalian University of TechnologyDalian 116024China Ningbo Institube of Dalian University of Technology Ningbo 315040China

Marine umbilical is one of the key equipment for subsea oil and gas exploitation,which is usually integrated by a great number of different functional components with *** layout of these components directly affects manufacturing,operation and storage performances of the *** the multi-layer cross-sectional layout design of the umbilical,a quantifiable multi-objective optimization model is established according to the operation and storage *** the manufacturing factors,the multi-layering strategy based on contact point identification is introduced for a great number of functional ***,the GA-GLM global optimization algorithm is proposed combining the genetic algorithm and the generalized multiplier method,and the selection operator of the genetic algorithm is improved based on the steepest descent *** algorithm is used to find the optimal solution in the global space,which can converge from any initial layout to the feasible layout *** feasible layout solution is taken as the initial value of the generalized multiplier method for fast and accurate ***,taking umbilicals with a great number of components as examples,the results show that the cross-sectional performance of the umbilical obtained by optimization algorithm is better and the solution efficiency is ***,the multi-layering strategy is effective and *** design method proposed in this paper can quickly obtain the optimal multi-layer cross-sectional layout,which replaces the manual design,and provides useful reference and guidance for the umbilical industry.

关键词： umbilical cross-sectional layout multi-layers GA-GLM optimization

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A novel method for determining the resistivity of compressed superconducting materials

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Matter and Radiation at Extremes 2024年第4期9卷 1-3页

作者： Liling Sun qi Wu Shu Cai Yang Ding Ho-kwang mao Center for High Pressure Science and Technology Advanced Research Beijing 100094China Institute of Physics Chinese Academy of SciencesBeijing 100190China

The measurement of resistivity in a compressed material within a diamond anvil cell presents significant *** high-pressure exper-imental setup makes it difficult to directly measure the size changes induced by pressure in the three crystallographic directions of the *** this study,we introduce a novel and effective method that addresses these technical *** method is anticipated to offer a valuable foundation for high-pressure investigations on quantum materials,particularly those with anisotropic layered structures.

关键词： resistivity method foundation

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Metal-free Optical Pressure Sensor with High Sensitivity and Extensive Range

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CSEE Journal of Power and Energy Systems 2024年第3期10卷 1291-1300页

作者： mao Ji Meng Huang Haomin Lyu Sheng Shi Bo qi Chengrong Li State Key Laboratory of Alternate Electrical Power System with Renewable Energy Sources North China Electric Power UniversityBeijing 102206China IEEE CSEE

Pressure monitoring of a transformer oil tank can grasp the pressure change process caused by gas production when severe internal defects occur and take timely measures to ensure the safe operation of the *** pressure sensors generally use metal encapsulation or have an air cavity structure,threatening the transformer’s insulation if it is directly used inside the *** this end,this paper proposes a method for developing a high-sensitivity,large-range,and metallizationfree optical pressure sensing device with temperature *** grating is encapsulated by fluorosilicone rubber and supplemented by an epoxy resin shielding shell on the *** the same time,a double-grating vertical arrangement is adopted to improve pressure measurement sensitivity,further avoiding the influence of temperature rise caused by a defect of the transformer on the measurement result of the *** addition,by optimizing the geometric structure of the internal sensitizing element,pre-stretching length of the fiber grating,gap distance,and other parameters,probe size can be reduced while ensuring the sensor’s *** show the proposed method can meet the requirements of sensor fabrication with different sensitivities and ranges,and to a certain extent,both high sensitivity and extensive ranges can be taken into *** sensitivity of the fabricated prototype is 15 pm/kPa,and the range is about 0.2 *** the same time,the metal-free feature of the sensor makes it suitable for use in various oil-immersed power *** records oil pressure changes caused by oil discharge breakdown,making it sensitive to small pressure changes in early failures.

关键词： Highly sensitive extensive range optical sensing no metallization pressure perception temperature compensation transformer

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