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Batch synthesis of rare-earth nickelates electronic phase transition perovskites via rare-earth processing intermediates

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Rare Metals 2022年第10期41卷 3495-3503页

作者： Xiao-Yu Li Zi-ang Li Feng-Bo Yan Hao Zhang Jia-ou Wang Xin-You Ke Yong Jiang Nuo-Fu Chen Ji-Kun Chen School of New Energy North China Electric Power UniversityBeijing102206China School of Materials Science and Engineering University of Science and Technology BeijingBeijing100083China Beijing Synchrotron Radiation Facility Institute of High Energy PhysicsChinese Academy of SciencesBeijing100049China Department of Mechanical and Aerospace Engineering Case Western Reserve UniversityClevelandOH44106USA

The rare-earth nickelates(RENiO_(3)) exhibit an exceptional complex electronic phase diagram and multiple electronic phase transitions that enrich promising applications in correlated electronic devices beyond conventional ***,the practical applications of RENiO_(3) are challenged by their intrinsic thermodynamic metastability in material synthesis and high material ***,developing an economical strategy to achieve the batch synthesis of RENiO_(3) is of vital *** this work,we enlarged the synthesis amount of RENiO_(3) up to 20 g per batch using chloride(KCI) assisted molten salt *** optimizing the reaction conditions,the powder of RENiO_(3) with the cubic shape and average size of ~2μm was effectively synthesized,while their phase purity exceeded 95%.In addition,the cost to synthesize RENiO_(3) was further reduced by using rare-earth extraction intermediate products as the raw materials,instead of using the pure rare-earth *** also achieved wide adjustments in the metal-to-insulator-transition temperature from160 to 420 K without significantly reducing the transition *** enlarging the synthesis amount and the reducing the cost,it paves the way to the device application of RENiO_(3).

关键词： Quantum materials Rare-earth nickelates Metastable materials Perovskite oxides

High-density lipoprotein regulates angiogenesis by affecting autophagy via miRNA-181a-5p

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Science China(Life Sciences) 2024年第2期67卷 286-300页

作者： Bi-ang Kang Hua-Ming Li Ya-Ting Chen Meng-Jie Deng Yan Li Yue-Ming Peng Jian-Jun Gao Zhi-Wei Mo Jia-Guo Zhou Zhi-Jun ou Jing-Song ou Division of Cardiac Surgery Cardiovascular Diseases InstituteThe First Affiliated HospitalSun Yat-sen UniversityGuangzhou 510080China National-Guangdong Joint Engineering Laboratory for Diagnosis and Treatment of Vascular Diseases Guangzhou 510080China NHC key Laboratory of Assisted Circulation(Sun Yat-sen University) Guangzhou 510080China Guangdong Provincial Engineering and Technology Center for Diagnosis and Treatment of Vascular Diseases Guangzhou 510080China Division of Vascular Surgery The First Affiliated HospitalSun Yat-sen UniversityGuangzhou 510080China Department of Pharmacology Cardiac and Cerebral Vascular Research CenterZhongshan School of MedicineSun Yat-sen UniversityGuangzhou 510080China Division of Hypertension and Vascular Diseases Department of CardiologyCardiovascular Diseases InstituteThe First Affiliated HospitalSun Yat-sen UniversityGuangzhou 510080China Guangdong Provincial Key Laboratory of Brain Function and Disease Zhongshan School of MedicineSun Yat-sen UniversityGuangzhou 510080China

We previously demonstrated that normal high-density lipoprotein(nHDL)can promote angiogenesis,whereas HDL from patients with coronary artery disease(d HDL)is dysfunctional and impairs *** plays a critical role in angiogenesis,and HDL regulates ***,it is unclear whether n HDL and d HDL regulate angiogenesis by affecting *** cells(ECs)were treated with n HDL and d HDL with or without an autophagy ***,endothelial nitric oxide synthase(e NOS)expression,miRNA expression,nitric oxide(NO)production,superoxide anion(O2^(·-))generation,EC migration,and tube formation were evaluated.n HDL suppressed the expression of miR-181a-5p,which promotes autophagy and the expression of e NOS,resulting in NO production and the inhibition of O2^(·-)generation,and ultimately increasing in EC migration and tube formation.d HDL showed opposite effects compared to n HDL and ultimately inhibited EC migration and tube *** found that autophagy-related protein 5(ATG5)was a direct target of ***5 silencing or miR-181a-5p mimic inhibited n HDL-induced autophagy,e NOS expression,NO production,EC migration,tube formation,and enhanced O2^(·-)generation,whereas overexpression of ATG5 or miR-181a-5p inhibitor reversed the above effects of d ***5 expression and angiogenesis were decreased in the ischemic lower limbs of hypercholesterolemic low-density lipoprotein receptor null(LDLr^(-/-))mice when compared to C57BL/6 ***5 overexpression improved angiogenesis in ischemic hypercholesterolemic LDLr^(-/-)*** together,nHDL was able to stimulate autophagy by suppressing miR-181a-5p,subsequently increasing e NOS expression,which generated NO and promoted *** contrast,d HDL inhibited angiogenesis,at least partially,by increasing miR-181a-5p expression,which decreased autophagy and e NOS expression,resulting in a decrease in NO production and an increase in O2^(·-)*** findings reveal a nov

关键词： high-density lipoprotein angiogenesis autophagy ATG5 miRNA endothelial nitric oxide synthase

The PPR protein RARE1-mediated editing of chloroplast accD transcripts is required for fatty acid biosynthesis and heat tolerance in Arabidopsis

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Plant Communications 2023年第1期4卷 217-227页

作者： Chao Huang Dan Liu Zi-ang Li David P.Molloy Zhou-Fei Luo Yi Su Hai-ou Li Qing Liu Ruo-Zhong Wang Lang-Tao Xiao College of Bioscience and Biotechnology Hunan Agricultural UniversityChangsha 410128China Department of Biochemistry and Molecular Biology School of Basic Medical ScienceChongqing Medical UniversityChongqing 400016China

It has been reported that Arabidopsis chloroplast accD transcripts undergo RNA editing and that loss of accD-C794 RNA editing does not affect plant growth under normal *** date,the exact biological role of accD-C794 editing has remained ***,we reveal an unexpected role for accD-C794 editing in response to heat *** of accD-C794 editing results in a yellow and dwarf phenotype with decreased chloroplast gene expression under heat stress,and artificial improvement of C794-edited accD gene expression enhances heat tolerance in *** data suggest that accD-C794 editing confers heat tolerance in *** also found that treatment with the product of acetyl coenzyme A carboxylase(ACCase)could allay mutant phenotypic characteristics and showed that a mutation in the CAC3 gene for the a-subunit of ACCase was associated with dwarfism under heat *** observations indicate that defective accD-C794 editing may be intrinsic to reduced ACCase activity,thereby contributing to heat *** catalyzes the committed step of de novo fatty acid(FA)*** content analysis revealed that unsaturated oleic(C18:1)and linoleic acids(C18:2)were low in the accD-C794 editing-defective mutant but high in the C794-edited accD-overexpressing plants compared with the wild *** exogenous C18:1 and C18:2 could rescue the mutant phenotype,suggesting that these FAs play an essential role in tolerance to heat *** electron microscopy observations showed that heat stress seriously affected the membrane architecture in accD editing-defective mutants but not in accD-overexpressing *** results provide the first evidence that accD-C794 editing regulates FA biosynthesis for maintenance of membrane structural homeostasis under heat stress.

关键词： chloroplast RNA editing RARE1 accD fatty acid heat stress

Application of Flower Borders in Hefei City

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Journal of Landscape Research 2024年第4期16卷 27-30页

作者： MENG Yuyang ZHAO Zhiyan ang Shengchao MENG Yi WEN Shiyang ou Xueni Department of Architecture and Landscape Design Anhui Xinhua UniversityHefei 230088China

The application value of 70 kinds of flowers in Hefei City was evaluated by analytic hierarchy process(AHP).From the three aspects of adaptability,ornamental value and economic traits,12 indicators were summarized to establish a comprehensive evaluation *** results show that the application of grade-I plants(J≥3.6642)in flower borders is the most suitable,and they include 19 species of plants such as Osmanthus fragrans ***,accounting for 27.14%.The application of grade-II plants(3.2319≤J≤3.6641)in flower borders is suitable,and 36 species of plants such as Jacobaea maritima are included,with the proportion of 51.42%.The application of grade-III plants(2.7935≤J≤3.2318)in flower borders is relatively suitable,and they contain 8 species of plants such as Acer palmatum’Atropurpureum’(Van Houtte)Schwerim,accounting for 11.42%.Grade-IV plants(J≤2.7934)can be applied in flower borders under special circumstances,and include 6 species of plants such as Muehlenbeckia complexa Meisn.,accounting for 8.57%.The results can provide reference for the selection of flower border plants in *** locations and types of 40 flower borders were summarized to provide a basis for the development direction and future planning of flower borders in Hefei.

关键词： Analytic hierarchy process(AHP) Flower border Application value Comprehensive evaluation

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线性规划在优化钻机动迁方案中的应用

西南石油大学学报（自然科学版） 2016年第3期38卷 144-149页

作者：刘昂谢刚欧瑾中国石油天然气勘探开发公司北京西城100034

钻井工程是油气田开发过程中的投资大项,而钻机服务费又是总钻井成本的主要构成,通过优化项目开发期间的钻机动迁方案,可以有效降低投资成本。结合工作实践,针对如何在开发期内优化钻机动迁的问题,探讨了混合整数线性规划方法在伊拉克... 详细信息

钻井工程是油气田开发过程中的投资大项,而钻机服务费又是总钻井成本的主要构成,通过优化项目开发期间的钻机动迁方案,可以有效降低投资成本。结合工作实践,针对如何在开发期内优化钻机动迁的问题,探讨了混合整数线性规划方法在伊拉克哈法亚油田钻机动迁方案优化中的应用,为项目运作的合理安排提供了科学的决策依据。不同于传统的钻机年度计划安排,混合整数线性规划利用了整个开发期的信息,以最小化钻机服务费为目标函数,根据年度钻井数量确定约束条件,优化模型求得开发期内每年需要各种钻机的数量。模型解优于年度钻机动迁计划,同时模型适应性强,响应快,最优解会根据工作量和约束条件的变化而调整,可以有效地提高工作效率。

关键词：混合整数线性规划优化钻机服务费钻机动迁方案伊拉克哈法亚油田

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中药安神制剂研发的探析

世界科学技术-中医药现代化 2014年第2期16卷 234-238页

作者：游秋云王平湖北中医药大学国家中医药管理局老年性痴呆醒脑益智重点研究室武汉430065 湖北中医药大学药学院武汉430065

随着各种压力的增大,失眠成为临床上常见疾病。对于失眠的治疗,安神中药制剂以其独特的优势发挥着显著的疗效。笔者就安神中药制剂的研发现状和存在的问题,以及具体实践研究作相关的探讨,以期为中药安神制剂的应用开发提供参考依据。

关键词：失眠安神中药制剂研究

High-density lipoprotein regulates angiogenesis by long non-coding RNA HDRACA

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Signal Transduction and Targeted Therapy 2023年第9期8卷 4320-4337页

作者： Zhi-Wei Mo Yue-Ming Peng Yi-Xin Zhang Yan Li Bi-ang Kang Ya-Ting Chen Le Li Mary GSorci-Thomas Yi-Jun Lin Yang Cao Si Chen Ze-Long Liu Jian-Jun Gao Zhan-Peng Huang Jia-Guo Zhou Mian Wang Guang-Qi Chang Meng-Jie Deng Yu-Jia Liu Zhen-Sheng Ma Zuo-Jun Hu Yu-Gang Dong Zhi-Jun ou Jing-Song ou Division of Cardiac Surgery Cardiovascular Diseases InstituteThe First Affiliated HospitalSun Yat-sen UniversityGuangzhouChina National-Guangdong Joint Engineering Laboratory for Diagnosis and Treatment of Vascular Diseases NHC Key Laboratory of Assisted Circulation(Sun Yat-sen University)Guangdong Provincial Engineering and Technology Center for Diagnosis and Treatment of Vascular DiseasesGuangzhouChina Division of Vascular Surgery The First Affiliated HospitalSun Yat-sen UniversityGuangzhouChina Division of Hypertension and Vascular Diseases Department of CardiologyHeart CenterThe First Affiliated HospitalSun Yat-sen UniversityGuangzhouChina Medical College of Wisconsin MilwaukeeWIUSA Center for Translational Medicine Institute of Precision MedicineThe First Affiliated HospitalSun Yat-sen UniversityGuangzhouChina Department of Cardiology Heart CenterThe First Affiliated HospitalSun Yat-sen UniversityGuangzhouChina Department of Pharmacology Cardiac and Cerebral Vascular Research CenterZhongshan School of Medicine of Sun Yat-sen UniversityGuangzhouChina Guangdong Provincial Key Laboratory of Brain Function and Disease Zhongshan School of MedicineSun Yat-sen UniversityGuangzhou 510080P.R.China

Normal high-density lipoprotein(nHDL)can induce angiogenesis in healthy ***,HDL from patients with coronary artery disease undergoes various modifications,becomes dysfunctional(dHDL),and loses its ability to promote ***,we identified a long non-coding RNA,HDRACA,that is involved in the regulation of angiogenesis by *** this study,we showed that nHDL downregulates the expression of HDRACA in endothelial cells by activating WW domain-containing E3 ubiquitin protein ligase 2,which catalyzes the ubiquitination and subsequent degradation of its transcription factor,Kruppel-like factor 5,via sphingosine 1-phosphate(S1P)receptor *** contrast,dHDL with lower levels of S1P than nHDL were much less effective in decreasing the expression of *** was able to bind to Ras-interacting protein 1(RAIN)to hinder the interaction between RAIN and vigilin,which led to an increase in the binding between the vigilin protein and proliferating cell nuclear antigen(PCNA)mRNA,resulting in a decrease in the expression of PCNA and inhibition of *** expression of human HDRACA in a hindlimb ischemia mouse model inhibited the recovery of *** together,these findings suggest that HDRACA is involved in the HDL regulation of angiogenesis,which nHDL inhibits the expression of HDRACA to induce angiogenesis,and that dHDL is much less effective in inhibiting HDRACA expression,which provides an explanation for the decreased ability of dHDL to stimulate angiogenesis.

关键词： angiogenesis lipoprotein inhibited

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基于社会演化算法的聚类新算法

情报杂志 2006年第5期25卷 5-6,10页

作者：郝占刚王正欧天津大学系统工程研究所天津300072

K均值聚类算法通常只能以局部最优结束,很难找到全局最优。提出了一种基于社会演化算法和K均值算法相结合的聚类新算法。在该算法中提出了认知主体在聚类中对范式学习的新的方式。实验证明该算法能大大提高聚类的效率和精度。

关键词：聚类社会演化算法 K均值算法

Thoracic Aortic Aneurysm Revealed by Haemoptysis on a 10-Year-Old Girl at Paediatrics Department of Yalgado ouedraogo University Hospital

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Open Journal of Pediatrics 2017年第1期7卷 13-17页

作者： Chantal Zoungrana ouattara Caroline Yonaba angèle Kalmogho Flore ouédraogo Chantal Bouda ousseini Diallo Ludovic Kam Departement de Pédiatrie Centre Hospitalier Universitaire Yalgado Ouédraogo Ouagadougou Burkina-Faso Departement d’imagerie Médicale et Radiodiagnostic Centre Hospitalier Universitaire Yalgado Ouédraogo Ouagadougou Burkina-Faso

Thoracic aortic aneurysm is a rather rare disorder in children and difficult to diagnose. It is generally linked to congenital heart defects or connective-tissue diseases. our case is a 10-year-old girl admitted in the pediatric emergency care unit on January 19th, 2015 for massive haemoptysis and severe anaemia. Examination revealed severe anemia and a silent left lung. The Chest X-Ray revealed an abnormal mass on the upper left side of the mediastinum, and left lower lobe consolidation. The thoracic CT scan highlighted a 64 mm aneurysm of the subisthmic aorta with a thin 5 mm hole. It also showed pseudocoarctation of the aorta. Treatment in intensive care consisted of blood transfusion and iron supplement. She was due to travel abroad for cardio vascular surgery, but died on November 2016. Thoracic Aortic Aneurysm in our setting was discovered incidentally. In spite the fact that it is an extreme surgical emergency, in Burkina Faso, treatment can only be possible abroad upon medical evacuation.

关键词： Aorta Aneurysm Haemoptysis Coarctation Burkina Faso