检索结果-南通市图书馆

微型全化学分析系统及技术进展

引用

高等学校化学学报 2000年第7期21卷 1028-1034页

作者：徐溢 EijkelJanC.T. manza. 重庆大学环境与化学化工学院重庆400044 Anal.Sci.Center

对微型全化学分析系统 (μ TAS)的发展现状及其应用领域进行了综述 ,对 μ TAS在毛细管电泳微型化、DNA及生化分析、组合化学研究等领域的应用研究作了重点介绍 .

关键词：微型全化学分析系统毛细管电泳微型化微屏片

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Assessment of groundwater quantity, quality, and associated health risk of the Tano river basin, Ghana

引用

Acta Geochimica 2024年第2期43卷 325-353页

作者： Adwoba Kua-manza.Edjah Bruce Banoeng-Yakubo Anthony Ewusi Enoch Sakyi-Yeboah David Saka Clara Turetta Giulio Cozzi David Atta-Peters Larry Pax Chegbeleh Water Resources Research Centre Ghana Atomic Energy CommissionAccraGhana Earth Science Department University of GhanaLegonAccraGhana Geological Engineering Department University of Mines and TechnologyTarkwaGhana Department of Statistics University of GhanaAccraLegonGhana Institute of Polar Sciences National Research Council of ItalyVeniceItaly

In the Tano River Basin,groundwater serves as a crucial resource;however,its quantity and quality with regard to trace elements and microbiological loadings remain poorly understood due to the lack of groundwater logs and limited water *** study presents a comprehensive analysis of the Tano River Basin,focusing on three key ***,it investigated the aquifer hydraulic parameters and the results showed signiﬁcant spatial variations in borehole depths,yields,transmissivity,hydraulic conductivity,and speciﬁc *** boreholes were concentrated in the northeastern and southeastern zones,while geological formations,particu-larly the Apollonian Formation,exhibit a strong inﬂuence on borehole *** study identiﬁed areas with high transmissivity and hydraulic conductivity in the southern and eastern regions,suggesting good groundwater avail-ability and suitability for sustainable water ***-ondly,the research investigated the groundwater quality and observed that the majority of borehole samples fall within WHO(Guidelines for Drinking-water Quality,Environmental Health Criteria,Geneva,2011,***://***)***,some samples have pH levels below the standards,although the groundwater generally qualiﬁes as *** study further explores hydrochemical facies and health risk assessment,highlighting the dominance of Ca–HCO3 water *** element analysis reveals minimal health risks from most elements,with chromium(Cr)as the primary contributor to chronic health ***,this study has provided a key insights into the Tano River Basin’s hydrogeology and associated health *** outcome of this research has contributed to the broader understanding of hydrogeologi-cal dynamics and the importance of managing groundwater resources sustainably in complex geological environments.

关键词： Groundwater Unsupervised machine learning technique Hydrochemistry Aquifer hydraulic parameter Health risk

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Neuroimaging of inflammation in alcohol use disorder: a review

引用

Science China(Information Sciences) 2020年第7期63卷 19-37页

作者： Dana E.FELDMAN Katherine L.MCPHERSON Catherine L.BIESECKER Corinde E.WIERS Peter manza.Nora D.VOLKOW Gene-Jack WANG National Institute on Alcohol Abuse and Alcoholism National Institute on Drug Abuse

Alcohol use disorder(AUD) is a global health concern associated with several *** health problems related to AUD, such as cognitive deficits, have been linked to *** use has been associated with changes in neuroimmune activity, although current literature has yielded mixed results. For example, markers of gliosis, including translocator protein 18-kDa(TSPO), proinflammatory cytokines, glutamate(Glu), and myo-inositol(mI), are disrupted in the alcohol-dependent brain. Further, neuroinflammatory-related phenomena including membrane turnover, blood brain barrier(BBB) permeability, and adenosine release have also shown alterations in AUD. However, current literature remains inconclusive about the directionality of these changes. Both in vivo and in vitro studies have provided insight on the relationship between alcohol use and neuroinflammatory processes, suggesting considerable treatment potential for alcohol use disorder and its inflammatory comorbidities. Here, we review current neuroimaging literature assessing the impacts of alcohol use on neuroimmune activity in the brain.

关键词： acetate adenosine alcohol use disorder blood brain barrier choline gliosis glutamate myoinositol neuroimaging neuroinflammation

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Ketamine use disorder:preclinical,clinical,and neuroimaging evidence to support proposed mechanisms of actions

引用

Intelligent Medicine 2022年第2期2卷 61-68页

作者： Leah Vines Diana Sotelo Allison Johnson Evan Dennis Peter manza.Nora D.Volkow Gene-Jack Wang Laboratory of Neuroimaging National Institute on Alcohol Abuse and AlcoholismNational Institutes of Health10 Center DrRm B2L124BethesdaMarylandUnited States

Ketamine,a noncompetitive N-methyl-D-aspartate(NMDA)receptor antagonist,has been exclusively used as an anesthetic in medicine and has led to new insights into the pathophysiology of neuropsychiatric *** studies have shown that low subanesthetic doses of ketamine produce antidepressant effects for individuals with ***,its use as a treatment for psychiatric disorders has been limited due to its reinforcing effects and high potential for diversion and *** studies have focused on understanding the molecular mechanisms underlying ketamine’s antidepressant effects,but a precise mechanism had yet to be *** we review different hypotheses for ketamine’s mechanism of action including the direct inhibition and disinhibition of NMDA receptors,aminomethylphosphonic acid receptors(AMPAR)activation,and heightened activation of monoaminergic *** proposed mechanisms are not mutually exclusive,and their combined influence may exert the observed structural and functional neural *** term use of ketamine induces brain structural,functional impairments,and neurodevelopmental effects in both rodents and *** misuse has increased rapidly in the past 20 years and is one of the most common addictive drugs used in *** proposed mechanisms of action and supporting neuroimaging data allow for the development of tools to identify‘biotypes’of ketamine use disorder(KUD)using machine learning approaches,which could inform intervention and treatment.

关键词： Ketamine Neuroimaging N-methyl-D-aspartate Dopamine Serotonin Glutamatergic Gamma-aminobutyric acid

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：