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American Journal of Plant Sciences 2012年第5期3卷 589-595页

作者： Christian Troncoso Jose Becerra Claudia Perez Victor Hernandez Aurelio San Martin manuel sanchez-olate Darcy Rios Centro de Biotecnologia Laboratorio de Cultivo de Tejidos Vegetales Universidad de Concepcion Concepcion Chile Departamento de Botanica Facultad de Ciencias Naturales y Oceanograficas Universidad de Concepcion Concepcion Chile Departamento de Quimica Facultad de Ciencias Universidad de Chile Santiago Chile Facultad de Ciencias Forestales Universidad de Concepcion Concepcion Chile

This study evaluated the expression of defense compounds from the secondary metabolism of Eucalyptus globulus plants, subjected to direct and indirect stimuli by the insect Ctenarytaina eucalypti (blue gum Psyllid). Results showed that defense responses were activated in plants in all tested cases. Were detected and identified thirty-two compounds in the leaves of treated plants, of which five compounds differed with the control, and all are part of the chemical defenses from the plants, three of them were oxygenated monoterpenes (borneol, exo-2-hydroxy cineole and thymol), a aromatic carboxylic acid (benzoic acid) and a quinone (6-acethyl-flaviolin). The plants induced by volatile compounds and by indirect entomological manner, showed its capability to synthesize defensive compounds without a wound that promotes these responses. Were also found some constitutive secondary metabolites over expressed in the different inductions compared with the control.

关键词： Chemical Defense E. globules Secondary Metabolites Terpenes

National assessment of the evolution of forest fragmentation in Mexico

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Journal of Forestry Research 2011年第2期22卷 167-174页

作者： Rafael Moreno-sanchez Francisco Moreno-sanchez Juan manuel Torres-Rojo University of Colorado Denver Department of Geography and Environmental SciencesCampus Box 172 P.O.Box 173364DenverCO 80217-3364USA Instituto Nacional de Investigaciones Forestales y Agropecuarias(INIFAP) Av Progreso #5CoyoacánMéxico D.F.04100México Centro de Investigación y Docencia Económicas(CIDE) Carretera México-Toluca 3655Col.Lomas de Santa FeMéxicoD.F.01210México

This paper presents assessments of the fragmentation of the temperate and tropical forests in Mexico at the national level for two dates 1993 and *** study was based on land use and vegetation cover data sets scale 1：250,*** broad forest types（Temperate Forests and Tropical Forests） and five more specific forest types（Broadleaf Forests,and Coniferous Forests;Tropical Dry Deciduous Forests,Tropical Sub-evergreen Forests,and Tropical Evergreen Forests） were defined to conduct the *** 3.3 was used to estimate nine metrics of the spatial pattern of the forests for each forest type and date *** results indicate that the land cover transitions that have occurred between 1993 and 2002 have resulted in more isolated forest patches with simpler shapes in both the Temperate and Tropical *** remaining Tropical Forest patches have become smaller and more *** contrast,the remaining Temperate Forest patches are fewer and on average *** the more specific forest types defined in this study,the Broadleaf Forests have the highest indicators of *** these forests are usually embedded or adjacent to Coniferous *** more concern for conservation purposes are the high values of fragmentation metrics found for the Tropical Evergreen Forests and Tropical Dry Deciduous Forests,because these forest types are usually surrounded by non-forest land covers or anthropogenic land uses.

关键词： forest fragmentation Mexico FragStats.

Pseudostress-BasedMixed Finite Element Methods for the Stokes Problem in Rn with Dirichlet Boundary Conditions.I:A Priori Error Analysis

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Communications in Computational Physics 2012年第6期12卷 109-134页

作者： Gabriel N.Gatica Antonio Marquez manuel A.sanchez CI2MA and Departamento de Ingenier´ıa Matem´atica Universidad de Concepci´onCasilla 160-CConcepcionChile Departamento de Construcci´on e Ingenier´ıa de Fabricacion Universidad de OviedoOviedoEspa-na.

We consider a non-standard mixed method for the Stokes problem in Rn,n∈{2,3},with Dirichlet boundary conditions,in which,after using the incompressibility condition to eliminate the pressure,the pseudostress tensor s and the velocity vector u become the only ***,we apply the Babuˇska-Brezzi theory to prove the well-posedness of the corresponding continuous and discrete *** particular,we show that Raviart-Thomas elements of order k≥0 for s and piecewise polynomials of degree k for u ensure unique solvability and stability of the associated Galerkin *** addition,we introduce and analyze an augmented approach for our pseudostress-velocity *** methodology employed is based on the introduction of the Galerkin least-squares type terms arising from the constitutive and equilibrium equations,and the Dirichlet boundary condition for the velocity,all of them multiplied by suitable stabilization *** show that these parameters can be chosen so that the resulting augmented variational formulation is defined by a strongly coercive bilinear form,whence the associated Galerkin scheme becomes well posed for any choice of finite element *** instance,Raviart-Thomas elements of order k≥0 for s and continuous piecewise polynomials of degree k+1 for u become a feasible choice in this ***,extensive numerical experiments illustrating the good performance of the methods and comparing them with other procedures available in the literature,are provided.

关键词： Mixed finite element pseudostress incompressible flow

Simultaneous pars plana vitrectomy,panretinal photocoagulation,cryotherapy,and Ahmed valve implantation for neovascular glaucoma

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International Journal of Ophthalmology(English edition) 2021年第9期14卷 1396-1401页

作者： Carolina Bernal-Morales Marina Dotti-Boada Alvaro olate-Perez manuel J.Navarro-Angulo Laura Pelegrín Marc Figueras-Roca Institut Clínic d’Oftalmologia(ICOF) Hospital ClínicBarcelona 08028Spain August Pi i Sunyer Biomedical Research Institute(IDIBAPS) Barcelona 08028Spain

AIM:To describe and evaluate the efficacy of Ahmed glaucoma valve implantation(AGV)combined with pars plana vitrectomy(PPV)in a single surgical act for the treatment of advanced neovascular glaucoma(NVG).METHODS:Retrospective observational case series included 51 eyes from 50 patients with severe NVG treated with PPV,AGV,and panretinal photocoagulation and/or cryotherapy in a single surgical act during a 13-year period(2005-2018).Preoperative,intraoperative and postoperative data at day 1 and months 1,3,6,21,and 24 were systematically *** of surgical success was stablished at IOP between 6 and 21 mm Hg with or without topical ***:Main indications for surgery were NVG secondary to proliferative diabetic retinopathy(39.2%)and central retinal vein occlusion(37.3%).Mean(±SD)preoperative IOP was 42.0±11.2 mm Hg decreasing to 15.5±7.1 mm Hg at 12 mo and 15.8±9.1 mm Hg at 24 mo of follow *** incidence of success of IOP control was 76.0%at first postoperative month,reaching 88.3%at 6 *** of successful IOP control at long term was 74.4%at 12 mo and 71.4%at 24 *** evisceration for unsuccessful NVG management was required in 1 case(2.0%).CONCLUSION:Combination of AGV implantation and PPV in a single act may be a suitable option for severe forms of NVG in a case-by-case basis for effective IOP control and a complete panretinal photocoagulation.

关键词： neovascular glaucoma Ahmed valve pars plana vitrectomy panretinal photocoagulation cryotherapy

Mesenchymal stem cells and cell-free preparations for treating atopic dermatitis

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BIOCELL 2022年第11期46卷 2363-2367页

作者： TRINIDAD MONTERO-VILCHEZ manuel sanchez-DIAZ CAROLINA MONTERO-VILCHEZ ALVARO SIERRA-sanchez SALVADOR ARIAS-SANTIAGO Dermatology Department Virgen de las Nieves University HospitalGranadaSpain Instituto de Investigación Biosanitaria Granada GranadaSpain Pharmacy Department Virgen de las Nieves University HospitalGranadaSpain Dermatology Department Faculty of MedicineUniversity of GranadaGranadaSpain

Atopic dermatitis(AD)is a chronic cutaneous inflammatory disease caused by an interaction between genetic,immune and epidermal barrier *** treatments can be used to treat this disease but there are patients that do not respond to actual ***,there is a need to develop effective therapies for *** stem cells(MSCs)are non-hematopoietic multipotent adult progenitor cells with immunomodulatory power and self-regenerating capacity to repair tissue damage,so they could be a potential effective treatment for ***-Conditioned Medium(CM)and MSCs-exosomes are cell-free preparation with molecules secreted by stem cells that could be also beneficial for *** viewpoint reviews the actual development of MSCs,MSCs-CM and MSCs-exosomes for treating patients with AD.

关键词： Atopic dermatitis Conditioned medium Dermatology Mesenchymal stem cells Stem cells

Gastrointestinal stromal tumors:a multidisciplinary challenge

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World Journal of Gastroenterology 2018年第18期24卷 1925-1941页

作者： Juan manuel sanchez-Hidalgo manuel Duran-Martinez Rafael Molero-Payan Sebastian Rufian-Pena Alvaro Arjona-sanchez Angela Casado-Adam Antonio Cosano-Alvarez Javier Briceno-Delgado Department of General and Digestive Surgery Reina Sofia University HospitalAvda.Menéndez Pidal s/nCordoba 14004Spain Department of Intern Medicine Reina Sofia University HospitalAvda.Menéndez Pidal s/nCordoba 14004Spain Lipids and Atherosclerosis Research Unit IMIBIC/Hospital Universitario Reina Sofía/Universidad de CórdobaCordoba 14004Spain

Gastrointestinal stromal tumors(GISTs) are the most common mesenchymal tumors located in the alimentary tract. Its usual manifestation is gastrointestinal bleeding. However, small asymptomatic lesions are frequently detected as incidental finding. Characteristically, most GISTs(> 95%) are positive for the KIT protein(CD117) by IHC staining and approximately 80%-90% of GISTs carry a mutation in the c-KIT or PDGFRA genes. Mutational analysis should be performed when planning adjuvant and neoadjuvant therapy, due to its possible resistance to conventional treatment. The arise of tyrosine kinase inhibitor has supposed a revolution in GISTs treatment being useful as adjuvant, neoadjuvant or recurrence disease treatment. That is why a multidisciplinary approach to this disease is required. The correct characterization of the tumor at diagnosis(the diagnosis of recurrences and the evaluation of the response to treatment with tyrosine kinase inhibitors) is fundamental for facing these tumors and requires specialized Endoscopist, Radiologists and Nuclear Medicine Physician. Surgery is the only potentially curative treatment for suspected resectable GIST. In the case of high risk GISTs, surgery plus adjuvantImatinib-Mesylate for 3 years is the standard treatment. Neoadjuvant imatinib-mesylate should be considered to shrink the tumor in case of locally advanced primary or recurrence disease, unresectable or potentially resectable metastasic tumors, and potentially resectable disease in complex anatomic locations to decrease the related morbidity. In the case of Metastatic GIST under Neoadjuvant treatment, when there are complete response, stable disease or limited disease progression, complete cytoreductive surgery could be a therapeutic option if feasible.

关键词： Gastrointestinal stromal tumors Surgery Oncology Radiology Endoscopy Nuclear medicine Pathology Disease management Tyrosine kinase inhibitors Gastroenterology

Contributions to data transmission at critical moments on unmanned aerial vehicles

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Chinese Journal of Aeronautics 2023年第8期36卷 247-257页

作者： Jose Enrique RODRIGUEZ David SEGURADO manuel sanchez Jose Javier MARTINEZ Rafael GONZALEZ National Institute of Aerospace Technology Madrid 28850Spain Department of Computer Science University of AlcalaAlcala de HenaresMadrid 28054Spain

As for unmanned aircraft, the knowledge of the aircraft performance is directly related with the navigation, guidance, and control system programming. Therefore, the measured data in each phase of the flight must be sufficiently precise to obtain a good characterization of *** article proposes new methods of sending information to ground, which make it possible to know the aircraft behavior accurately, and for this purpose, four contributions have been made for ALO(Avión Ligero de Observación, Spanish acronym for Light Observation Aircraft). Currently, the characterization is based on data obtained at ten samples per second, insufficient to acquire detailed knowledge of what happened during the whole flight of an aircraft. As a result of these contributions, many more samples per second of accelerations and angular velocities are obtained at the most critical moments of the flight, such as takeoff or landing. Among the improvements included are data compression techniques, providing references to locate the measured data in time and identifying labels of each parameter.

关键词： Critical moments Data transmission Datacompression tech-niques Radio-modem Recommended Standard 232(RS-232) Unmannedaerial vehicle

Complications of extrahepatic echinococcosis:Fistulization of an adrenal hydatid cyst into the intestine

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World Journal of Gastroenterology 2008年第9期14卷 1467-1469页

作者： Juan Francisco Ruiz-Rabelo manuel Gomez-Alvarez Joaquin sanchez-Rodriguez Sebastian Rufian Pea Department of General Surgery Reina Sofia University Hospital Avda Menendez Pidal S/N Cordoba 14004 Spain

Echinococcal cysts are usually found in liver and lungs, but any other organ can potentially be involved. Extrahepatic disease due to hydatid cyst may develop in the abdominal and pelvic cavity, aside from in other less common locations, which may make both diagnosis and treatment more complex. We present a rare case of extrahepatic echinococcosis in a 70-year old patient with a 4-d history of dull abdominal pain, anemia within the transfusion range and fever. She underwent surgery for left renal hydatid cysts 30 years ago. After non operative treatment, imaging studies showed a calcified hydatid cyst in a retrogastric location communicating with a proximal jejunal loop. En-block resection of the mass together with the adrenal gland was performed including closure of the enteric fistula. Anatomic pathology confirmed the diagnosis of a calcified hydatid cyst of left adrenal origin. Surgery is the treatment of choice and most authors recommend removal of cyst and adrenal gland.

关键词： Echinococcosis Adrenal cyst Surgery

National assessment of the fragmentation,accessibility and anthropogenic pressure on the forests in Mexico

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Journal of Forestry Research 2012年第4期23卷 529-541页

作者： Rafael Moreno-sanchez Juan manuel Torres-Rojo Francisco Moreno-sanchez Sue Hawkins Justin Little Susan McPartland University of Colorado Denver Department of Geography and Environmental SciencesCampus Box 172 P.O.Box 173364DenverCO 80217-3364USA. Centro de Investigación y Docencia Económicas(CIDE) Carretera México-Toluca 3655Col.Lomas de Santa FeMéxicoD.F.01210México. Instituto Nacional de Investigaciones Forestales y Agropecuarias(INIFAP) Av Progreso #5CoyoacánMéxico D.F.04100México Department of Geography and Environmental Sciences University of Colorado DenverCampus Box 172 P.O.Box 173364 DenverCO 80217-3364USA

Forest managers and policy makers increasingly demand to have access to estimates of forest fragmentation, human accessibility to forest areas and levels of anthropogenic pressure on the remaining forests to integrate them into monitoring systems, management and conservation plans. Forest fragmentation is defined as the breaking up of a forest unit, where the number of patches and the amount of expose edge increase while the amount of core area decreases. Forest fragmentation studies in Mexico have been limited to local or regional levels and have concen- trated only on specific forest types. This paper presents an assessment of the fragmentation of all forest types at the national level, their effective proximity to anthropogenic influences, and the development of an indica- tor of anthropogenic pressure on the forests areas. Broadleaf forests, tropical evergreen forests and tropical dry deciduous forests show the greatest fragmentation. Almost half （47%） of the tropical forests are in close effective proximity to anthropogenic influences and only 12% of their area can be considered isolated from anthropogenic influences. The values for the temperate forests are 23% and 29% respectively. Anthro- pogenic pressure in the immediate vicinity of anthropogenic activities is much higher in the tropical forests （75 in a scale 0-100） than in the tem- perate forests （30）. When considering these results jointly, the tropical forests, and more specifically, the tropical evergreen forests and tropical dry deciduous forests are under the greatest pressure and risks of degra- dation.

关键词： forest fragmentation effective proximity anthropogenicpressure Mexico forests GIS.

Clinical presentation and early predictors for poor outcomes in pediatric myocarditis:A retrospective study

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World Journal of Clinical Cases 2019年第5期7卷 548-561页

作者： Moises Rodriguez-Gonzalez Maria Isabel sanchez-Codez manuel Lubian-Gutierrez Ana Castellano-Martinez Department of Pediatric Cardiology Puerta del Mar University Hospital Department of Pediatrics Puerta del Mar University Hospital Department of Pediatric Nephrology Puerta del Mar University Hospital

BACKGROUND Myocarditis is an important cause of morbidity and mortality in children, leading to long-term sequelae including chronic congestive heart failure, dilated cardiomyopathy, heart transplantation, and death. The initial diagnosis of myocarditis is usually based on clinical presentation, but this widely ranges from the severe sudden onset of a cardiogenic shock to asymptomatic patients. Early recognition is essential in order to monitor and start supportive treatment prior to the development of severe adverse events. Of note, many cases of fulminant myocarditis are usually misdiagnosed as otherwise minor conditions during the weeks before the unexpected *** To provide diagnostic clues to make an early recognition of pediatric *** investigate early predictors for poor *** We conducted a retrospective cross-sectional single-center study from January 2008 to November 2017 at the Pediatric Department of our institution, including children < 18-years-old diagnosed with myocarditis. Poor outcome was defined as the occurrence of any of the following facts: death, heart transplant, persistent left ventricular systolic dysfunction or dilation at hospital discharge(early poor outcome), or after 1 year of follow-up(late poor outcome). We analyzed different clinical features and diagnostic test findings in order to provide diagnostic clues for myocarditis in children. Multivariable stepwise logistic regression analysis was performed using all variables that had been selected by univariate analysis to determine independent factors that predicted a poor early or late outcome in our study *** A total of 42 patients [69% male; median age of 8(1.5-12) years] met study inclusion criteria. Chest pain(40%) was the most common specific cardiac symptom. Respiratory tract symptoms(cough, apnea, rhinorrhea)(38%),shortness of breath(35%), gastrointestinal tract symptoms(vomiting, abdominal pain, diarrhea)(33%), and fever(31%) were

关键词： Myocarditis Children Echocardiography N-terminal pro-brain natriuretic peptide Myocardial ischemia Cardiac magnetic resonance imaging Heart transplantation Dilated cardiomyopathy