检索结果-南通市图书馆

Microglial activation and adult neurogenesis after brain stroke

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2021年第3期16卷 456-459页

作者： Ijair R.C.dos santos Michelle Nerissa C.dias Walace Gomes-Leal Laboratory of Experimental Neuroprotection and Neuroregeneration Institute of Biological SciencesFederal University of Pará-BrazilBelém-ParáBrazil

The discovery that new neurons are produced in some regions of the adult mammalian brain is a paradigm-shift in neuroscience *** new-born cells are produced from neuroprogenitors mainly in the subventricular zone at the margin of the lateral ventricle,subgranular zone in the hippocampal dentate gyrus and in the striatum,a component of the basal ganglia,even in *** the human hippocampus,neuroblasts are produced even in *** regulation of adult neurogenesis is a complex phenomenon involving a multitude of molecules,neurotransmitters and soluble factors released by different sources including glial ***,the resident macrophages of the central nervous system,are considered to play an important role on the regulation of adult neurogenesis both in physiological and pathological *** stroke and other acute neural disorders,there is an increase in the numbers of neuroblast production in the neurogenic *** activation is believed to display both beneficial and detrimental role on adult neurogenesis after stroke,depending on the activation level and brain *** this article,we review the scientific evidence addressing the role of microglial activation on adult neurogenesis after ischemia.A comprehensive understanding of the microglial role after stroke and other neural disorders it is an important step for development of future therapies based on manipulation of adult neurogenesis.

关键词： adult neurogenesis hippocampus ischemia microglia neuroinflammation neuroprotection stroke subventricular zone therapy

Dealing with Multisource Information for Estuarine Flood Risk Appraisal in Two Western European Coastal Areas

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

International Journal of Disaster Risk Science 2022年第2期13卷 199-213页

作者： Ana Rodrigues Rilo Alexandre manuel de Oliveira Soares Tavares Paula Maria dos santos Freire José Luis Zêzere Estuarine and Coastal Zones Unit LNEC-National Civil Engineering Laboratory.1700-075 LisbonPortugal Centre of Geographical Studies Institute of Geography and Spatial PlanningUniversidade de Lisboa1700-066 LisbonPortugal Centre for Social Studies and Earth Sciences Department Coimbra University3030-790 CoimbraPortugal

Estuaries are usually affected by compound flooding triggers that cause diverse territorial *** fluvial flood risk assessment frameworks are well established in the literature,integrated management instruments that deal with estuarine flood risk remain incomplete and often *** research presents a methodology to extract relevant information from multiple sources post-event and a database building process that is applied to two contrasting estuaries(the Tagus River estuary in Portugal,and the Shannon River estuary in Ireland)in the Western European coastal ***,a total of 274 documents were analyzed and the information was stored in two *** correspondence analysis was applied to extract the most informative and relevant estuarine flood *** integrated estuarine flood risk assessment framework is presented and discussed based on the extracted *** framework is driven by two distinct dimensions(oceanic and hydrographic)and revealed the transversal position of triggers of estuarine floods,reflecting the compounding effects usually present in these *** results also highlight two levels of flood risk mostly based on damage typology.

关键词： Estuarine floods Estuarine flood indicators Multiple correspondence analysis Post-hazard multisource information Western Europe

Structural phase relations in perovskite-structured BiFeO_(3)-based multiferroic compounds

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Journal of Advanced Ceramics 2013年第2期2卷 103-111页

作者： Valdirlei Fernandes FREITAS Gustavo Sanguino dias Otávio Algusto PROTZEK Diogo Zampieri MONTANHER Igor Barbosa CATELLANI Daniel Matos SILVA Luiz Fernando CÓTICA Ivair Aparecido dos santos UEM-Universidade Estadual de Maringá GDDM-Grupo de Desenvolvimento de Dispositivos MultifuncionaisDepartamento de FísicaMaringáBrazil

In this review,the state of the art in understanding the structural phase relations in perovskite-structured BiFeO_(3)-based polycrystalline solid solutions is presented and *** about the close relation between the structural phase and overall physical properties of the reviewed systems are pointed out and *** is shown that,by adjusting the structural symmetric arrangement,the ferroelectric and magnetic properties of BiFeO_(3)-based polycrystalline solid solutions can be tuned to find specific multifunctional ***,an intrinsic mechanism linking structural arrangement and physical properties cannot be identified,revealing that this subject still deserves further discussion and investigation.

关键词： bismuth ferrite ferroelectrics multiferroics

Hydrodynamics and suspended particulate matter retention in macrotidal estuaries located in Amazonia-semiarid interface(Northeastern-Brazil)

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Sediment Research 2020年第4期35卷 417-429页

作者： Vinicius Henrique Maciel dos santos Francisco Jose da Silva dias Audalio Rebelo Torres Romulo Araujo Soares Lais Costa Terto Antonio Carlos Leal de Castro Ricardo Luvizotto santos Marco Valerio Jansen Cutrim Laboratorio de Hidrodinamica Costeira Estuarina e de Aguas Interiores (LHiCEAI) Do Programa de Pos-Graduacao Em Oceanografia (PPGOceano) da Universidade Federal Do Maranhao (UFMA)Cidade Universitaria Dom Delgado Laboratorio de Ictiologia (LabIctio) da Universidade Federal Do Maranhao (UFMA) Cidade Universitaria Dom Delgado Laboratorio de Ecotoxicologia (LabEcotox) Do Programa de Pos-Graduacao Em Oceanografia (PPGOceano) da Universidade Federal Do Maranhao (UFMA) Cidade Universitaria Dom Delgado Laboratorio de Ficologia (LabFic) Do Programa de Pos-Graduacao Em Oceanografia (PPGOceano) da Universidade Federal Do Maranhao (UFMA) Cidade Universitaria Dom Delgado

The aim of the current study was to determine the nature of the seasonal variability of the Suspended Particulate Matter(SPM) fluxes from the drainage basin to the estuary in a macrotidal region(Northeastern Brazil),and the estuarine response to a seawater intrusion regarding sediment deposition,which will support the understanding of the global transport of materials at the continent-ocean *** structure data was acquired using a Conductivity,Temperature,and Depth(CTD) probe with a sampling frequency of 4 *** particulate material was measured by gravimetric measurements applied to exact filtered volume *** outflows were measured through the use of an Acoustic Doppler Current Profiler(ADCP) with frequency of 1.5 *** horizontal thermal and saline gradients varied from warmer and less saline waters(2014) to cooler and saline waters(2015).The gradient behavior when linked to volume transport and SPM flows,suggests a minimization of the fluvial flows in 2015,easing the advance of coastal water(CW) towards the inner estuary,leading to an inversion of the baroclinic pressure *** bottom saline front,generated by the entrance of coastal water masses,caused an increase in SPM concentrations due to increased fluid density,resuspension of previously deposited sediment,and erosion of *** concentrations of SPM indicate higher volume transport suggesting a hydraulic barrier due to the change/inversion of the baroclinic pressure gradient,resulting in water and material *** deposition was observed during neap tide,while during spring tide the material is resuspended,increasing the concentration,generating cycles of deposition and erosion during the neap-spring *** sediment in suspension that reach the estuary,even with low fluvial volume,stay in this environment forming new islands because of *** deposition rates or sediment cycling,if generated by the hydraulic barrier,may indicate that the flo

关键词： Brazilian Amazonia Materials discharges Macrotidal estuaries Freshwater percentage Residence time

On Boolean Functions Associated to Finite Aligned Spaces

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Journal of Mathematics and System Science 2018年第3期8卷 74-76页

作者： Jose manuel dos santos Simoes Pereira Department of Mathematics University of Coimbra Coimbra 3000373 Portugal

Boolean or switching functions can be associated to finite aligned spaces in a way similar to the way they can be associated to finite topological spaces. We prove a characterization of switching functions associated to aligned spaces which is similar to the one we have given for switching functions associated to finite topological spaces.

关键词： Aligned space topological space boolean function switching function.

Biomass-glycerol briquettes are not necessarily mechanically stable and energetically effective

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Waste Disposal and Sustainable Energy 2020年第4期2卷 291-303页

作者： Bruno Rafael de Almeida Moreira Ronaldo da Silva Viana Samuel dias Moreira Monique dos santos Lima Anderson Chagas Magalhães Celso Tadao Miasaki JoséClaudio Caraschi Department of Phytosanitary Rural Engineering and SoilsSchool of EngineeringSão Paulo State University(Unesp)Ilha SolteiraSão PauloBrazil Department of Plant Production College of Agricultural and Technological SciencesSão Paulo State University(Unesp)DracenaBrazil São Paulo State University(Unesp) ItapevaSão PauloBrazil

The re-use of glycerol from biodiesel industry as an alternative lubricant for making high-performance briquettes is ***,the technical performance of this agro-industrial residue is not *** study outlines,accordingly,the real risk of introducing glycerol into the co-briquetting of highly caloric by-products of *** production of hybrid briquettes consisted of pressing mixtures of residues of sugarcane and sorghum with the liquid additive at 10,20,and 30 wt.%in bench-scale hydraulic piston presser *** of the blend,briquettes containing the supplement at the highest level as part of their composition ended up being much more hygroscopic(20.10%)and less energetic(3.15 GJ m^(−3)).The explanation for the negative impact of glycerol on the thermomechanical behavior of briquettes would be overconcen-tration of additive capable of effectively defying compacting *** degree of compaction during co-briquetting has likely gone down quickly with a maximizing level of *** long as the additive is not able to lubricate the feedstock suitably,improbability of biomass particles to successfully bond together to form themselves into mechanically stable and energetically effective briquettes is *** lower density(273.80 kg m^(−3))and higher relaxation(22.75%),briquettes with glycerol at 30 wt.%generally were aesthetically ***,these products resisted no longer to handling,transportation,and *** lost their shape easily during emptying and shifting them,thus,releasing larger quanti-ties of biomass to the *** evidence of high-viscosity glycerol capable of limiting safe and effective production of high-performance briquettes for heating and power exists.

关键词： Additive Agro-residues Densification Biosolids Waste-to-energy

An Overview of the Amazonian Craton Evolution: Insights for Paleocontinental Reconstruction

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Geosciences 2015年第9期6卷 1060-1076页

作者： Mauro Cesar Geraldes Armando dias Tavares Anderson Costa dos santos Rio de Janeiro State University Maracana Rio de Janeiro Brazil

The Amazonian craton major accretionary and collisional processes may be correlated to supercontinent assemblies developed at several times in the Earth history. Based on geologic, structural and paleomagnetic evidence paleocontinent reconstructions have been proposed for Archean to younger times. The oldest continent (Ur) was formed probably by five Achaean cratonic areas (Kaapvaal, Western Dhawar, Bhandara, Singhhum and Pilbara cratons). Geologic evidences suggest the participation of the Archaean rocks of the Carajás region in the Ur landmass. Supercontinental 2.45 Ga Kenorland amalgamation is indicated by paleomagnetic data including Laurentia, Baltica, Australia, and Kalahari and Kaapvaal cratons. There is no evidence indicating that Amazonian craton was part of the Kenorland supercontinent. From 1.83 Ga to 1.25 Ga Columbia and Hudsonland supercontinents including Amazonian craton were proposed based on NE portion of the Amazonian craton (Maroni/Itacaiunas province) connection with West Africa and Kalahari cratons. Rodinia supercontinent reconstructions show Amazonia joined to Laurentia-Baltica as result of 1.1 Ga to 1.0 Ga fusion based on the Sunsas-Aguapei belts and Greenville and Sveconorwegian belts, respectivelly. The large Late Mesoproterozoic landmass included also Siberia, East Antartica, West Nile, Kalahari, Congo/Sao Francisco and Greenland. The 750 - 520 Ma Gondwana assembly includes most of the continental fragments rifted apart during the break-up of Rodinia followed by diachronic collisions (Araguaia, Paraguay and Tucavaca belts). The supercontinent Pangea is comprised of Gondwana and Laurentia formed at about 300 - 180 Ma ago. The Amazonian craton margins probably were not envolved in the collisional processes during Pangea because it was embebed in Neoproterozoic materials. As consequence, Amazonian craton borders have no record of the orogenic processes responsible for the Pangea amalgamation.

关键词： Amazonian Craton Tectonic Evolution Paleocontinents

Mannosylated glycans impair normal T-cell development by reprogramming commitment and repertoire diversity

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Cellular & Molecular Immunology 2023年第8期20卷 955-968页

作者： manuel M.Vicente Inês Alves Ângela Fernandes Ana M.dias Beatriz santos-Pereira Elena Pérez-Anton Sofia santos Tao Yang Alexandra Correia Anja Münster-Kühnel Afonso R.M.Almeida Sarina Ravens Gabriel A.Rabinovich manuel Vilanova Ana E.Sousa SaloméS.Pinho i3S–Institute for Research and Innovation in Health University of PortoPortoPortugal Institute of Biomedical Sciences Abel Salazar(ICBAS) University of PortoPortoPortugal Graduate Program in Areas of Basic and Applied Biology(GABBA) ICBASUniversity of PortoPortoPortugal Faculty of Medicine University of PortoPortoPortugal Nephrology Department Centro Hospitalar e Universitário do PortoPortoPortugal Institute of Immunology Hannover Medical SchoolHannoverGermany Institute of Clinical Biochemistry Hannover Medical SchoolHannoverGermany Instituto de Medicina Molecular João Lobo Antunes Faculdade de MedicinaUniversidade de LisboaLisboaPortugal Laboratorio de Inmunopatología Instituto de Biología y Medicina Experimental(IBYME)Consejo Nacional de Investigaciones Científicas y Técnicas(CONICET)Ciudad de Buenos AiresArgentina Laboratorio de Inmuno-oncología Translacional Instituto de Biología y Medicina Experimental(IBYME)Consejo Nacional de Investigaciones Científicas y Técnicas(CONICET)Ciudad de Buenos AiresArgentina Facultad de Ciencias Exactas y Naturales(FCEyN) Universidad de Buenos AiresCiudad de Buenos AiresArgentina

T-cell development ensures the formation of diverse repertoires of T-cell receptors(TCRs)that recognize a variety of *** is a major posttranslational modification present in virtually all cells,including T-lymphocytes,that regulates activity/*** these structures are known to be involved in TCR-selection in DP thymocytes,it is unclear how glycans regulate other thymic development processes and how they influence susceptibility to ***,we discovered stage-specific glycome compositions during T-cell development in human and murine thymocytes,as well as dynamic *** restricting the N-glycosylation profile of thymocytes to high-mannose structures,using specific glycoengineered mice(Rag1CreMgat1fl/fl),we showed remarkable defects in key developmental checkpoints,includingß-selection,regulatory T-cell generation andγδT-cell development,associated with increased susceptibility to colon and kidney inflammation and *** further demonstrated that a single N-glycan antenna(modeled in Rag1CreMgat2fl/fl mice)is the sine-qua-non condition to ensure normal *** conclusion,we revealed that mannosylated thymocytes lead to a dysregulation in T-cell development that is associated with inflammation susceptibility.

关键词： N-glycosylation T-cell development Thymocytes Glycocalyx Inflammation

Study of Reinforcement Distribution,Adhesion between Layers,and Porosity Induced by FDM

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

材料科学与工程（中英文A版） 2021年第2期11卷 56-62页

作者： Arthur Wernke Rafael dos santos Leonardo santos manuel Barcelos Jr Emmanuel Lima Laboratório Associado de Sensores e Materiais Instituto Nacional de Pesquisas Espaciais(INPE)Avenida dos Astronautas 1758São Josédos Campos-SP 12245-970Brazil Faculdade do Gama(FGA) Universidade de Brasília(UnB)St.Leste Projeção AGama-DF 72444-240Brazil

This study aims to understand the distribution of reinforcement material in the matrix,evaluate the adherence between layers,and determine the air gap between printing *** printed the specimen with two different composite materials,Polylactic Acid(PLA)reinforced with acrylic particles,and another filament reinforced with short carbon *** the observations of the samples,we used a Confocal *** estimated the porosity of the material by comparing the expected mass with that achieved after *** pixel count,after binarization,we found the average percentage of acrylate *** showed fair distribution through the PLA matrix even after the manufacturing *** determination of fibers alignment was made by binarization of image,together with k-means and edge *** combination of methods allows estimating the fiber alignment by orientation straight *** manufacturing process did not offer good alignment of the fibers,even with the filament initially well aligned.

关键词： 3D printing porosity in 3D printed parts 3D printed composite materials