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Real-time-guided bone regeneration around standardized critical size calvarial defects using bone marrow-derived mesenchymal stem cells and collagen membrane with and without using tricalcium phosphate: an in vivo microcomputed tomographic and histologic e

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International Journal of Oral Science 2016年第1期8卷 7-15页

作者： Khalid al-Hezaimi Sundar Ramalingam mansour al-askar Aws S ArRejaie Nasser Nooh Fawad Jawad Abdullah aldahmash Muhammad Atteya Cun-Yu Wang Engineer A.B.Growth Factors and Bone Regeneration Research Chair and 3D Imaging Center College of DentistryKing Saud UniversityRiyadhSaudi Arabia Department of Periodontics and Community Dentistry College of DentistryKing Saud UniversityRiyadhSaudi Arabia Department of Oral and Maxillofacial Surgery College of DentistryKing Saud UniversityRiyadhSaudi Arabia Department of Substitutive Dental Sciences College of DentistryUniversity of DammamDammamSaudi Arabia Stem Cell Unit Department of AnatomyCollege of MedicineKing Saud UniversityRiyadh Division of Oral Biology and Medicine School of DentistryUniversity of California at Los AngelesLos AngelesUSA

The aim of the present real time in vivo micro-computed tomography （pCT） and histologic experiment was to assess the efficacy of guided bone regeneration （GBR） around standardized calvarial critical size defects （CSD） using bone marrow-derived mesenchymal stem cells （BMSCs）, and collagen membrane （CM） with and without tricalcium phosphate （TCP） graft material. In the calvaria of nine female Sprague-Dawley rats, full-thickness CSD （diameter 4.6 mm） were created under general anesthesia. Treatment-wise, rats were divided into three groups. In group 1, CSD was covered with a resorbable CM; in group 2, BMSCs were filled in CSD and covered with CM; and in group 3, TCP soaked in BMSCs was placed in CSD and covered with CM. all defects were closed using resorbable sutures. Bone volume and bone mineral density of newly formed bone （NFB） and remaining TCP particles and rate of new bone formation was determined at baseline, 2, 4, 6, and 10 weeks using in vivo pCT. At the lOth week, the rats were killed and calvarial segments were assessed histologically. The results showed that the hardness of NFB was similar to that of the native bone in groups I and 2 as compared to the NFB in group 3. Likewise, values for the modulus of elasticity were also significantly higher in group 3 compared to groups 1 and 2. This suggests that TCP when used in combination with BMSCs and without CM was unable to form bone of significant strength that could possibly provide mechanical ＂lock＂ between the natural bone and NFB. The use of BMSCs as adjuncts to conventional GBR initiated new bone formation as early as 2 weeks of treatment compared to when GBR is attempted without adiunct BMSC therapy.

关键词： bone marrow-derived mesenchymal stem collagen membrane critical size defect guided bone regeneration tricalciumphosphate

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Characteristics of newly-formed cementum following emdogain application

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International Journal of Oral Science 2011年第1期3卷 21-26页

作者： Khalid al-Hezaimi mansour al-askar Abdulaziz al-Rasheed Eng.A.B.Bagshan Growth Factors and Bone Regeneration Research Chair King Saud UniversityRiyadhSaudi Arabia Department of Periodontology School of Dentistry King Saud UniversityRiyadh Saudi Arabia Eng.A.B.Bagshan Growth Factors and Bone Regeneration Research Chair King Saud UniversityRiyadh Saudi Arabia Department of Periodontology School of Dentistry King Saud UniversityRiyadhSaudi Arabia

Periodontal regenerative techniques have been proposed; however, the outcomes remain debatable. The present investigation assessed the regenerated cementum following enamel matrix derivative application in dehiscence-type defects. Buccal osseous dehiscences were surgically created on the maxillary cuspid, and the second and fourth premolars in five female beagle dogs. The treatment group （n=15 sites） received the enamel matrix derived application, whereas the control groups （n=15） did not. The dogs were sacrificed 4 months following treatment and the specimens were histologically and histometrically examined. The newly formed cementum was uneven in thickness and mineralization, overlapped the old cementum and exhibited functional orientation, cementocyte lacunae and collagen fibril bundles. Most of the histological specimens showed the presence of a gap between the newly formed cementum and the underlying dentin. Control sites did not exhibit any cementum formation. The present study concluded that newly formed cementum is of cellular type and exhibits multiple characteristics.

关键词： regeneration cementum enamel matrix protein

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Facies development and sedimentology of the Middle Miocene carbonates of the Raghama Formation, northeastern Saudi Arabia

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Acta Geochimica 2024年第1期43卷 87-96页

作者： mansour H.al-Hashim Abdelbaset S.El-Sorogy Meshal Wadani Department of Geology and Geophysics College of ScienceKing Saud University2455Riyadh 11451Saudi Arabia

Ragahama Formation comprises a siliciclastic continental deposits followed by marine carbonates, representing prograding alluvial fans from adjacent high hinterlands seaward into lagoons and fringing reef environments. The present work aimed to document the facies development and sedimentology of the Raghama carbonates exposed along the eastern coastal plain of the Red Sea, northwestern Saudi Arabia. Four stratigraphic sections were measured and sampled(D1–D4) and thin sections and major and trace element analyses were prepared and applied for petrographic and geochemical approaches. The carbonates were subdivided into three successive fore-reef, reef-core, and back-reef depositional facies. Sandy stromatolitic boundstone, microbial laminites, dolomitic ooidal grainstone, bioclastic coralline algal wackestone, sandy bioclastic wackestone, and coral boundstones were the reported microfacies types. Petrographic analysis reveals that the studied carbonates were affected by dissolution, dolomitization, and aggrading recrystallization, which affects both the original micrite matrix and grains or acts as fracture and veinlet filling leading to widespread vuggy and moldic porosity. No evidence of physical compaction, suggesting rapid lithification and recrystallization during early diagenesis and prior to substantial burial and intensive flushing by meteoric waters. Most of the original microstructure of corals were leached and destructed. This is indicated by the higher depletion in Sr and Ca levels and increase in Mg,Na, Fe, and Mn levels, especially in section D1, in comparison with the worldwide carbonates.

关键词： Raghama Formation Miocene Diagenesis Geochemistry Saudi Arabia

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Examining the Use of Scott’s Formula and Link Expiration Time Metric for Vehicular Clustering

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Computer Modeling in Engineering & Sciences 2024年第3期138卷 2421-2444页

作者： Fady Samann Shavan askar Department of Energy Engineering Technical College of EngineeringDuhok Polytechnic UniversityDuhok42001Iraq Department of Information System Engineering Technical College of EngineeringErbil Polytechnic UniversityErbil44001Iraq

Implementing machine learning algorithms in the non-conducive environment of the vehicular network requires some adaptations due to the high computational complexity of these algorithms.K-clustering algorithms are simplistic,with fast performance and relative ***,their implementation depends on the initial selection of clusters number(K),the initial clusters’centers,and the clustering *** paper investigated using Scott’s histogram formula to estimate the K number and the Link Expiration Time(LET)as a clustering *** traffic flows were considered for three maps,namely Highway,Traffic Light junction,and Roundabout junction,to study the effect of road layout on estimating the K number.A fast version of the PAM algorithm was used for clustering with a modification to reduce time *** Affinity propagation algorithm sets the baseline for the estimated K number,and the Medoid Silhouette method is used to quantify the ***++,Veins,and SUMO were used to simulate the traffic,while the related algorithms were implemented in *** Scott’s formula estimation of the K number only matched the baseline when the road layout was ***,the clustering algorithm required one iteration on average to converge when used with LET.

关键词： Clustering vehicular network Scott’s formula FastPAM

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An Intelligent MCGDM Model in Green Suppliers Selection Using Interactional Aggregation Operators for Interval-Valued Pythagorean Fuzzy Soft Sets

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Computer Modeling in Engineering & Sciences 2024年第5期139卷 1829-1862页

作者： Rana Muhammad Zulqarnain Wen-Xiu Ma Imran Siddique Hijaz Ahmad Sameh askar School of Mathematical Sciences Zhejiang Normal UniversityJinhua321004China Department of Mathematics and Statistics University of South FloridaTampaFL 33620-5700USA School of Mathematical and Statistical Sciences North-West UniversityMafikeng CampusMmabatho2735South Africa Department of Mathematics University of SargodhaSargodha40100Pakistan Section of Mathematics International Telematic University UninettunoCorso Vittorio Emanuele IIRoma00186Italy Near East University Operational Research Center in HealthcareNicosia/Mersin99138Turkey Department of Statistics and Operations Research College of ScienceKing Saud UniversityRiyadh11451Saudi Arabia

Green supplier selection is an important debate in green supply chain management(GSCM),attracting global attention from scholars,especially companies and *** frequently search for new ideas and strategies to assist them in realizing sustainable *** of the speculative character of human opinions,supplier selection frequently includes unreliable data,and the interval-valued Pythagorean fuzzy soft set(IVPFSS)provides an exceptional capacity to cope with excessive fuzziness,inconsistency,and inexactness through the decision-making *** main goal of this study is to come up with new operational laws for interval-valued Pythagorean fuzzy soft numbers(IVPFSNs)and create two interaction operators-the intervalvalued Pythagorean fuzzy soft interaction weighted average(IVPFSIWA)and the interval-valued Pythagorean fuzzy soft interaction weighted geometric(IVPFSIWG)operators,and analyze their *** operators are highly advantageous in addressing uncertain problems by considering membership and non-membership values within intervals,providing a superior solution to other ***,specialist judgments were calculated by the MCGDM technique,supporting the use of interaction AOs to regulate the interdependence and fundamental partiality of green supplier assessment ***,a statistical clarification of the planned method for green supplier selection is presented.

关键词： Interval-valued Pythagorean fuzzy soft set IVPFSIWA operator IVPFSIWG operator MCGDM SCM

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抗菌光动力和激光治疗辅助机械清创在口臭治疗中的效果评价:系统综述

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中国口腔医学继续教育杂志 2019年第6期22卷 362-367页

作者： Sergio Varela Kellesarian Vanessa Ros Malignaggi Abdulaziz A.al-Kheraif mansour al-askar Michael Yunker Fawad Javed 李博亚(译) 韩莹(审) 不详北京大学口腔医院黏膜科北京市海淀区100081

目的:本项研究的目的是评价激光疗法(laser therapy,LT)和抗菌光动力疗法(antimicrobial photodynamic ***)辅助机械清创术(mechanical ***)治疗口臭的疗效。数据来源:为了表述"与单独使用机械清创(MD)相比,辅助使用激光疗法(LT)和/或... 详细信息

目的:本项研究的目的是评价激光疗法(laser therapy,LT)和抗菌光动力疗法(antimicrobial photodynamic ***)辅助机械清创术(mechanical ***)治疗口臭的疗效。数据来源:为了表述"与单独使用机械清创(MD)相比,辅助使用激光疗法(LT)和/或抗菌光动力疗法(APDT)的MD在口臭治疗中的效果更佳吗?"这个核心问题,截至2017年1月,在索引数据库中进行了无时间或语言限制的电子搜索,使用了不同关键词的组合,包括光化学治疗、激光、光、光动力疗法、口臭、口腔异味。排除标准包括定性和/或定量综述、病例报告、系列病例、评论、致编辑的信函、访谈和临床顾问。结果:纳入6个随机对照试验,并进行数据提取。所有研究的结果表明,与单独使用MD相比,联合LT或aPDT的MD在降低口臭和/或与口腔状况相关的挥发性硫化合物浓度方面更有效。一项研究报道,与仅单独使用MD相比,接受MD联合舌背外用光敏剂aPDT治疗的患者.舌背的细菌菌落数显著减少。结论:aPDT和/或LT治疗口臭的疗效尚不清楚。还需要进行进一步精心设计的随机临床试验,评估口臭治疗中进行机械清创同时使用LT或aPDT的效果。

关键词：口臭激光牙周疾病光化学治疗光动力治疗

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Explainable Conformer Network for Detection of COVID-19 Pneumonia from Chest CT Scan: From Concepts toward Clinical Explainability

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Computers, Materials & Continua 2024年第1期78卷 1171-1187页

作者： Mohamed Abdel-Basset Hossam Hawash Mohamed Abouhawwash S.S.askar alshaimaa A.Tantawy Faculty of Computers and Informatics Zagazig UniversityZagazig44519Egypt Department of Computational Mathematics Scienceand Engineering(CMSE)Michigan State UniversityEast LansingMI48824USA Department of Mathematics Faculty of ScienceMansoura UniversityMansoura35516Egypt Department of Statistics and Operations Research College of ScienceKing Saud UniversityP.O.Box 2455Riyadh11451Saudi Arabia

The early implementation of treatment therapies necessitates the swift and precise identification of COVID-19 pneumonia by the analysis of chest CT *** study aims to investigate the indispensable need for precise and interpretable diagnostic tools for improving clinical decision-making for COVID-19 *** paper proposes a novel deep learning approach,called Conformer Network,for explainable discrimination of viral pneumonia depending on the lung Region of Infections(ROI)within a single modality radiographic CT ***,an efficient U-shaped transformer network is integrated for lung image ***,a robust transfer learning technique is introduced to design a robust feature extractor based on pre-trained lightweight Big Transfer(BiT-L)and finetuned on medical data to effectively learn the patterns of infection in the input ***,this work presents a visual explanation method to guarantee clinical explainability for decisions made by Conformer *** evaluation of real-world CT data demonstrated that the diagnostic accuracy of ourmodel outperforms cutting-edge studies with statistical *** Conformer Network achieves 97.40% of detection accuracy under cross-validation *** model not only achieves high sensitivity and specificity but also affords visualizations of salient features contributing to each classification decision,enhancing the overall transparency and trustworthiness of our *** findings provide obvious implications for the ability of our model to empower clinical staff by generating transparent intuitions about the features driving diagnostic decisions.

关键词： Deep learning COVID-19 multi-modal medical image fusion diagnostic image fusion

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Einstein Hybrid Structure of q-Rung Orthopair Fuzzy Soft Set and Its Application for Diagnosis of Waterborne Infectious Disease

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Computer Modeling in Engineering & Sciences 2024年第5期139卷 1863-1892页

作者： Rana Muhammad Zulqarnain Hafiz Khalil ur Rehman Imran Siddique HijazAhmad Sameh askar Shahid Hussain Gurmani School of Mathematical Sciences Zhejiang Normal UniversityJinhua321004China Department of Mathematics Government College UniversityFaisalabad38000Pakistan Department of Mathematics University of SargodhaSargodha40100Pakistan Section of Mathematics International Telematic University UninettunoCorso Vittorio Emanuele IIRoma3900186Italy Near East University Operational Research Center in HealthcareNear East BoulevardNicosia/Mersin 1099138Turkey Department of Statistics and Operations Research College of ScienceKing Saud UniversityPO Box 2455Riyadh11451Saudi Arabia

This research is devoted to diagnosing water-borne infectious diseases caused by floods employing a novel diagnosis approach,the Einstein hybrid structure of q-rung orthopair fuzzy soft *** approach integrates parts of fuzzy logic and soft set theory to develop a robust alternative for disease detection in stressful situations,especially in areas affected by *** to the traditional intuitionistic fuzzy soft set and Pythagorean fuzzy soft set,the q-rung orthopair fuzzy soft set(q-ROFSS)adequately incorporates unclear and indeterminate *** major objective of this investigation is to formulate the q-rung orthopair fuzzy soft Einstein hybrid weighted average(q-ROFSEHWA)operator and its specific ***,our stated operator is implementing intelligentmulti-criteria group decision-making(MCGDM)*** are severe natural catastrophes that raise the risk of diseases and epidemics,particularly those caused by contaminants in the water,such as gastrointestinal diseases,respiratory infections,vector-borne diseases,skin infections,and water-borne *** designed MCGDM strategy tackles the prevalence of certain conditions in flood-affected patients.A comparative investigation determined that the suggested method for detecting water-borne infectious disease due to floods is more effective and productive than conventional methods because of its logical structure.

关键词： q-rung orthopair fuzzy soft set q-ROFSEHWA operator MCGDM environmental disaster water-born infection disease

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Cognitive-emotional feasibility of the effect of visual quality of building form on promoting the sense of place attachment(Case study:Cultural iconic buildings of Iran’s contemporary architecture)

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Frontiers of Architectural Research 2024年第1期13卷 37-56页

作者： Narmin Ariannia Negar Naseri mansour Yeganeh Digital Architecture and Artificial Intelligence Lab Department of ArchitectureTarbiat Modares UniversityTehranIran Architectural Design Modeling and Fabrication LabDepartment of ArchitectureTarbiat Modares UniversityTehranIran

The present research studies the relationship between place attachment and the perception of form’s visual quality in fifteen outstanding contemporary Iranian architectural cultural *** study puts forward the hypothesis that there is a correlation between the quality of building form and the sense of place attachment,in the sense that creating high visual quality through enhancing the quality of building form increases citizens’initial satisfaction with and subsequent attachment to the *** visual quality influences people’s experience of the environment and improves the quality of *** attachment highlights how people,on a personal level,recreate a sense of place for *** present study adopts the descriptive-analytical method as its theoretical framework and the survey as the empirical *** were developed using the Likert scale and distributed among experts and ordinary *** analysis using SPSS and the adoption of descriptive-analytical statistics,correlation analysis,and regression showed the relationship among the characteristics of *** results show a positive correlation between form and place attachment mediated through visual quality,and they are causal conditions for one *** addition,only some of the buildings under study evoke the same level of place attachment.

关键词： Visual preferences Environmental quality Environmental psychology Mental schemas Contemporary architecture

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Calibration of CO and CO₂ Monitors Used in Periodic Inspection of Vehicles at Fixed Stations for Environmental Control

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Green and Sustainable Chemistry 2024年第2期14卷 29-41页

作者： Adel Bassuoni Shehata Abdulrahman Rashed al askar Najjy Hamad al Yami Abdullah Suleiman al Owaysi Sultan K. alharbi Chemistry Department National Measurement and Calibration Center (NMCC) Saudi Standards Metrology and Quality Organization (SASO) Riyadh Kingdom of Saudi Arabia

Global efforts for environmental cleanliness through the control of gaseous emissions from vehicles are gaining momentum and attracting increasing attention. Calibration plays a crucial role in these efforts by ensuring the quantitative assessment of emissions for informed decisions on environmental treatments. This paper describes a method for the calibration of CO/CO2 monitors used for periodic inspections of vehicles in cites. The calibration was performed in the selected ranges: 900 - 12,000 µmol/mol for CO and 2000 - 20,000 µmol/mol for CO2. The traceability of the measurement results to the SI units was ensured by using certified reference materials from CO/N2 and CO2/N2 primary gas mixtures. The method performance was evaluated by assessing its linearity, accuracy, precision, bias, and uncertainty of the calibration results. The calibration data exhibited a strong linear trend with R² values close to 1, indicating an excellent fit between the measured values and the calibration lines. Precision, expressed as relative standard deviation (%RSD), ranged from 0.48 to 4.56% for CO and from 0.97 to 3.53% for CO2, staying well below the 5% threshold for reporting results at a 95% confidence level. Accuracy measured as percent recovery, was consistently high (≥ 99.1%) for CO and ranged from 84.90% to 101.54% across the calibration range for CO2. In addition, the method exhibited minimal bias for both CO and CO2 calibrations and thus provided a reliable and accurate approach for calibrating CO/CO2 monitors used in vehicle inspections. Thus, it ensures the effectiveness of exhaust emission control for better environment.

关键词： Monitors Periodic Inspection CO/CO2 Calibration Linearity Precision Accuracy

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