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Machine Learning Applied to Problem-Solving in Medical Applications

Computers, Materials & Continua 2021年第11期69卷 2277-2294页

作者： Mahmoud Ragab Ali Algarni Adel A.Bahaddad Romany F.mansour Department of Information Technology Faculty of Computing and Information TechnologyKing Abdulaziz UniversityJeddah21589Saudi Arabia Centre for Artificial Intelligence in Precision Medicine King Abdulaziz UniversityJeddah21589Saudi Arabia Department of Statistics Faculty of ScienceKing Abdulaziz UniversityJeddah21589Saudi Arabia Department of Information Systems Faculty of Computing and Information TechnologyKing Abdulaziz UniversityJeddah21589Saudi Arabia Department of Mathematics Faculty of ScienceNew Valley UniversityEl-Kharga72511Egypt

Physical health plays an important role in overall well-being of the human *** is the most observed dimension of health among others such as social,intellectual,emotional,spiritual and environmental *** to exponential increase in the development of wireless communication techniques,Internet of Things(IoT)has effectively penetrated different aspects of human *** is one of the dynamic domains with ever-growing demands which can be met by IoT *** can be leveraged through several health service offerings such as remote health and monitoring services,aided living,personalized treatment,and so *** this scenario,Deep Learning(DL)models are employed in proficient disease *** current research work presents a new IoT-based physical health monitoring and management method using optimal Stacked Sparse Denoising Autoencoder(SSDA)technique i.e.,*** proposed model utilizes a set of IoT devices to collect the data from *** class problem poses serious challenges during disease diagnosis ***,the OSSDA model includes Synthetic Minority Over-Sampling Technique(SMOTE)to generate artificial minority class instances to balance the class ***,the hyperparameter settings of the OSSDA model exhibit heavy influence upon the classification performance of SSDA *** number of hidden layers,sparsity,and noise count are determined by Sailfish Optimizer(SFO).In order to validate the effectiveness and performance of the proposed OSSDA technique,a set of experiments was conducted on diabetes and heart disease *** simulation results portrayed a proficient diagnostic outcome from OSSDA technique over other *** proposed method achieved the highest accuracy values i.e.,0.9604 and 0.9548 on the applied heart disease and diabetes datasets respectively.

关键词： IoT patient monitoring physical health deep learning parameter tuning

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Outgrowth endothelial cells form a functional cerebral barrier and restore its integrity after damage

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Neural Regeneration Research 2020年第6期15卷 1071-1078页

作者： Rais Reskiawan Abdulkadir mansour Alwjwaj Othman Ahmad Othman Kamini Rakkar Ulvi Bayraktutan Stroke Division of Clinical Neuroscience Clinical Sciences Building School of MedicineHucknall Road Nottingham NG5 1PB UK

Breakdown of blood-brain barrier,formed mainly by brain microvascular endothelial cells(BMECs),represents the major cause of mortality during early phases of ischemic ***,discovery of novel agents that can effectively replace dead or dying endothelial cells to restore blood-brain barrier integrity is of paramount importance in stroke *** endothelial progenitor cells(EPCs)represent one such agents,their rarity in peripheral blood severely limits their adequate isolation and therapeutic use for acute ischemic stroke which necessitate their ex vivo expansion and generate early EPCs and outgrowth endothelial cells(OECs)as a *** analyses of these cells,in the present study,demonstrated that only OECs endocytosed DiI-labelled acetylated low-density lipoprotein and formed tubules on matrigel,prominent endothelial cell and angiogenesis markers,*** analyses by flow cytometry demonstrated that OECs expressed specific markers for sternness(CD34),immaturity(CD133)and endothelial cells(CD31)but not for hematopoietic cells(CD45).Like BMECs,OECs established an equally tight in vitro model of human BBB with astrocytes and pericytes,suggesting their capacity to form tight *** injury mimicked by concurrent deprivation of oxygen and glucose(4 hours)or deprivation of oxygen and glucose followed by reperfusion(20 hours)affected both barrier integrity and function in a similar fashion as evidenced by decreases in transendothelial electrical resistance and increases in paracellular flux,*** scratch assays comparing the vasculoreparative capacity of cells revealed that,compared to BMECs,OECs possessed a greater proliferative and directional migratory *** a triple culture model of BBB established with astrocytes,pericytes and BMEC,exogenous addition of OECs effectively repaired the damage induced on endothelial layer in serum-free *** together,these data demonstrate that OECs may effect

关键词： cell-based therapy endothelial progenitor cells endothelium ischemic stroke neurodegeneration novel therapeutics outgrowth endothelial cells regenerative medicine stem cells translational medicine

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Facies development and sedimentology of the Middle Miocene carbonates of the Raghama Formation, northeastern Saudi Arabia

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Acta Geochimica 2024年第1期43卷 87-96页

作者： mansour H.Al-Hashim Abdelbaset S.El-Sorogy Meshal Wadani Department of Geology and Geophysics College of ScienceKing Saud University2455Riyadh 11451Saudi Arabia

Ragahama Formation comprises a siliciclastic continental deposits followed by marine carbonates, representing prograding alluvial fans from adjacent high hinterlands seaward into lagoons and fringing reef environments. The present work aimed to document the facies development and sedimentology of the Raghama carbonates exposed along the eastern coastal plain of the Red Sea, northwestern Saudi Arabia. Four stratigraphic sections were measured and sampled(D1–D4) and thin sections and major and trace element analyses were prepared and applied for petrographic and geochemical approaches. The carbonates were subdivided into three successive fore-reef, reef-core, and back-reef depositional facies. Sandy stromatolitic boundstone, microbial laminites, dolomitic ooidal grainstone, bioclastic coralline algal wackestone, sandy bioclastic wackestone, and coral boundstones were the reported microfacies types. Petrographic analysis reveals that the studied carbonates were affected by dissolution, dolomitization, and aggrading recrystallization, which affects both the original micrite matrix and grains or acts as fracture and veinlet filling leading to widespread vuggy and moldic porosity. No evidence of physical compaction, suggesting rapid lithification and recrystallization during early diagenesis and prior to substantial burial and intensive flushing by meteoric waters. Most of the original microstructure of corals were leached and destructed. This is indicated by the higher depletion in Sr and Ca levels and increase in Mg,Na, Fe, and Mn levels, especially in section D1, in comparison with the worldwide carbonates.

关键词： Raghama Formation Miocene Diagenesis Geochemistry Saudi Arabia

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Use of axial dispersion model for determination of Sherwood number and mass transfer coefficients in a perforated rotating disc contactor

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Chinese Journal of Chemical Engineering 2017年第1期25卷 53-61页

作者： Mehdi Asadollahzadeh Alireza Hemmati Meisam Torab-Mostaedi mansour Shirvani Ahad Ghaemi Zahra Sadat Mohsenzadeh Nuclear Fuel Cycle Research School Nuclear Science and Technology Research Institute P.O. Box： 11365-8486 Tehran Iran School of Chemical Engineering Iron University of Science and Technology Tehran P.O. Box 16765-163 Iran Department of Chemical Engineering Faculty of Engineering South Tehran Branch Islamic Azad University Iran

The mass transfer process in a perforated rotating disk contactor(PRDC) using a toluene-acetone-water system was *** volumetric overall mass transfer coefficients are calculated in a PRDC *** mass transfer directions are considered in *** influences of operating variables containing agitation rate,dispersed and continuous phase flow rates and mass transfer in the extraction column are *** to obtained results,mass transfer is significantly dependent on agitation rate,while the dispersed and continuous phase flow rates have a minor effect on mass transfer in the extraction ***,a novel empirical correlation is developed for prediction of overall continuous phase Sherwood number based on dispersed phase holdup,Reynolds number and mass transfer *** has been great agreement between experimental data and predicted values using a proposed correlation for all operating conditions.

关键词： Perforated rotating disk contactor Mass transfer coefficient dispersed phase holdup Interfacial area

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Induced Surface Austenitic-Martensitic Transition by Mechanical Deformation in Mn *** of Surface Properties

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Journal of Iron and Steel Research International 2011年第S1期18卷 223-227页

作者： Boutarek-Zaourar Nama mansour Samir Amara Sif Eddine USTHB FGMGPBP 32 EL ALIA BAB EZZOUARALGER USTHB FCBP 32 EL ALIA BAB EZZOUARALGER

For a lot of applications in the mechanical industry,both attractive and mechanical properties of materials and wear resistance are *** such a combination is achieved only by performing surface *** aim of this investigation is the consolidation of 12% Mn steel surface by treatment of *** show by optical and scanning electron microscopy,X ray diffraction,X ray spectrometry analysis and also by the realization of micro hardness,the effect of this kind of treatment on the mechanical and structural stability of the surface *** of many obtained results,we distinguish the clear surface consolidation induced by a modification of surface zone crystalline *** mechanical deformation causes the transformation from an austenitic structure to the martensitic structure.

关键词： phase transition Mn steel mechanical deformation surface properties impact treatment

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A survey on Hibiscus rosa-sinensis,Alcea rosea *** Malva neglecta Wallr as antibacterial agents

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Asian Pacific Journal of Tropical Medicine 2010年第5期3卷 351-355页

作者： Seyyed mansour Seyyednejad Haniyeh Koochak Esmaeil Darabpour Hossein Motamedi Department of Biology Faculty of ScienceShahid Chamran University

Objective:To guide for selection of plants with antibacterial activity for further phytochemical works on the isolation and identification of the active ***:Ethanolic extracts of 3 species from Malvaceae family were evaluated by agar disc diffusion method for antibacterial activity against some gram-positive and gram-negative bacteria(Pseudomonas aeruginosa,Listeria monocytogenes,Staphylococcus *** aureus, Klebsiella *** typhi,Bacillus *** anthracis,Escherichia coli and Streptococcus pyogenes).The extracts were obtained from aerial parts of Hibiscus rosa(H. rosa)-sinensis(leaf and flower),Alcea rosea(***) L.(leaf and flower) and Malva neglecta(M. neglecta) Wallr(flower).Results:These extracts had inhibitory effects at different concentrations (0.05,0.10,0.20 and 0.40 g/mL) against above mentioned *** coli was the most resistant *** highest inhibitory zone was showed by ethanolic extract of *** against Staphylococcus epidermidis(22 mm) and followed by ethanolic extract from flower of *** against Staphylococcus epidermidis and Staphylococcus aureus(20 mm).The Minimum Inhibitory Concentration(MIC) and Minimum Bactericidal Concentration(MBC) values against Staphylococcus epidermidis were equal(M1C=MBC=5 mg/mL for *** extract and for H. rosa extract MIC=MBC=20 mg/mL).Conclusions:These findings suggest that these native plants have good antibacterial properties that can be used for infection control and treatment and could also be as new source for antibiotics discovery and infection treatment.

关键词： Alcea rosea Antibacterial activity Ethanolic extract Hibiscus rosa-sinensis Malva neglecta

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Emphysematous sloughed floating ball after prostate water vaporization Rezum:A case report

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World Journal of Clinical Cases 2023年第23期11卷 5525-5529页

作者： mansour Alnazari Abdulaziz Bakhsh Emad Sabri Rajih Department of Urology Taibah UniversityMadinah 16655Al MadinahSaudi Arabia Urology Section Department of SurgeryKing Faisal Specialist Hospital&Research CenterMadinahSaudi Arabia

BACKGROUND Rezūm™water vapor therapy is a new minimally invasive endoscopic technology for the management and treatment of benign prostatic *** SUMMARY A 63-year-old male presented to our department with severe dysuria,frequency,urgency,and interrupted stream 2 mo after receiving Rezūm™*** symptoms were caused by a retained floating emphysematous necrotic sloughed *** also discovered a persistent bacterial infection that was resistant to parenteral antimicrobial *** treatment of the patient included surgical removal of the necrotic *** Despite the good safety profile and minimal adverse events related to Rezūm™therapy,major complications can still occur.

关键词： Benign prostatic hyperplasia Rezum Lower urinary tract symptoms Minimally invasive therapy Water vapor therapy Transurethral resection of the prostate Case report

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Synthesis of a New Class of Highly Functionalized Phosphorus Ylides Containing Heterocyclic Compounds

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Chinese Journal of Chemistry 2012年第8期30卷 1893-1900页

作者： Shaabani Ahmad Keshipour Sajjad Aghaei Morteza Khodabandeh M. Hassan Zahedi mansour Department of Chemistry Shahid Beheshti University G. C. P. O. Box 19396-4716 Tehran Iran

The zwitterionic intermediate generated from the reaction of triphenylphosphine with electron deficient acety- lenic compounds was trapped by various NH acids. The synthesis resulted in a new class of highly functionalized heterocyclic compounds. Some of the reactions produced E and Z isomers. And the stability and transformation of them were studied by dynamic 1H NMR and density functional theory （DFT） calculations.

关键词： highly functionalized heterocyclic compounds phosphorus ylides triphenylphosphine DFT dynamic 1H NMR

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Hepatocellular carcinoma with complete response to the immunotherapy:the oncologist’s dilemma

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Hepatobiliary Surgery and Nutrition 2022年第1期11卷 119-122页

作者： mansour Al-Moundhri Antonio Cubisino Fabrizio Panaro Medical Oncology Department Sultan Qaboos Comprehensive Cancer CenterSultan Qaboos UniversityMuscatOman Department of Surgery University of Illinois at ChicagoChicagoILUSA Department of Surgery Montpellier University HospitalMontpellierFrance Surgical Oncology Department Sultan Qaboos Comprehensive Cancer CenterSultan Qaboos UniversityMuscatOman

Hepatocellular carcinoma(HCC)is the seventh most common cancer and the fourth leading cause of cancer-related death worldwide(1).During the last decade,many efforts have been made to improve patient survival by conducting clinical trials investigating local and systemic treatment options for patients with unresectable ***,despite significant research efforts,only few treatment approaches have been validated for HCC.

关键词： cancer immunotherapy clinical

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Y^(3+) substituting-adjusted mechanical,dielectric,and impedance properties of cobalt copper zinc nanoferrites for high frequency applications

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Journal of Rare Earths 2023年第10期41卷 1597-1605,I0005页

作者： S.F.mansour N.S.Al-Bassami M.Afifi M.A.Abdo Physics Department Faculty of ScienceZagazig UniversityZagazigEgypt General Studies Department Jubail Industrial CollegeJubail Industrial CitySaudi Arabia Faculty of Nanotechnology for Postgraduate Studies Cairo UniversityEl-Sheikh Zayed12588Egypt

Upgrading mechanical-dielectric features of ferrites through rare-earth yttrium(Y^(3+))doping provides feasibility to evolving high-frequency electronic *** paper reports the mechanical and dielectric properties of Co_(0.5)Cu_(0.25)Zn_(0.25)Y_(x)Fe_(2-x)O_(4)ferrite nanoparticles labeled as CCZYF#0,CCZYF#1,CCZYF#2,CCZYF#3,CCZYF#4 and CCZYF#5 for x=0.***.0.02,0.04,0.06,0.08,and 0.1,*** frequency and temperature dependence of dielectric parameters and co nductivity of all CCZYF nanoferrites are well *** nanoferrite CCZYF#5 has the highest dielectric constant(enhancing ratio 170%)and the highest conductivity(enhancing ratio 7125.81%)compared with the undoped *** plots of all CCZYF nano ferrites manifest two arcs;the main reasons for the dielectric process are the grain boundaries and bulk *** impedance parameters were determined,which showed the effective role of Y^(3+)ions on their *** nanoferrite CCZYF#5 has the highest grain boundaries capacitance(with enhancing ratio of 59.40%)and the highest grains capacitance(with enhancing ratio of 22.53%)with a relaxation time decrement efficiency of 62.51%.An ultrasonic flaw detector was utilized to determine the elastic moduli of all CCZYF *** nanoferrite CCZYF#5 has the highest longitudinal modulus(with enhancing ratio of 20.95%),the highest shear modulus(with enhancing ratio of48.72%),highest Young's modulus(with enhancing ratio of 88.47%),the highest bulk modulus(with enhancing ratio 13.27%)and the highest micro hardness(with enhancing ratio 77.77%).Hence,Y3+tuned Co-Cu-Zn nanoferrites possess new opportunities for high-frequency and storage applications.

关键词： Nanoferrites Rare arth ions Mechanical properties Dielectric parameters Impedance spectroscopy

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