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Neuroprotective effects of a mitochondrial K^+-ATP channel opener (diazoxide) are mediated by Bcl-2 expression upregulation

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Neural Regeneration Research 2011年第12期6卷 956-960页

作者： Majid Katebi mansooreh soleimani Mehdi Mehdizadeh Department of Anatomy School of MedicineHormozgan University of Medical Sciences Cellular and Molecular Research Center Tehran University of Medical Sciences Department of Anatomy School of MedicineTehran University of Medical Sciences Research Institute for Islamic & Complementary Medicine Tehran University of Medical Sciences

Mitochondrial K＋-ATP （mito-KATP） channels play an important role in cellular function and survival following ischemic stress. The present results revealed that intervention with diazoxide, a mito-KATP channel opener, led to an increase in Bcl-2 expression in the cerebral cortex of rats subjected to cerebral ischemia reperfusion injury. In addition, the intervention also led to clear improvements in neuronal mitochondrial morphology and consciousness post-injury. Glibenclamide a mito-KATP channel blocker, exhibited the converse effects. Both diazoxide and glibenclamide exerted dose-dependent effects （in particular, at 18 mg/kg diazoxide and 25 mg/kg glibenclamide）. These findings suggest that diazoxide exerts a neuroprotective effect on cerebral ischemia reperfusion injury by opening mito-KATP channels and upregulating Bcl-2 expression.

关键词： K-ATP channel Bcl-2 cerebral ischemia reperfusion injury diazoxide

Activated Hard Shell of Apricot Stones： A Promising Adsorbent in Gold Recovery

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Chinese Journal of Chemical Engineering 2008年第1期16卷 112-118页

作者： mansooreh soleimani Tahereh Kaghazchi Faculty of Chemical Engineering AmirKabir University of Technology Tehran 15875-4413 Iran

Activated carbon has been proven to be an effective adsorbent for the recovery of a wide variety of metal ions from aqueous solutions. In this research, the activated hard shell of Iranian apricot stones was used for gold recovery from electro-plating wastewater. The effect of parameters such as dose and particle size of adsorbent,pH, agitation speed of mixing on the gold recovery was investigated. The results showed that under the optimum operating conditions more than 98% of gold ions were adsorbed onto activated carbon after just 3 h. In addition, the adsorbed gold could be eluted from this adsorbent by improved striping method. The process involves contact of gold-laden adsorbent with a strong base at ambient temperatures followed by elution with an aqueous solution containing an organic solvent. It was found that activated hard shell of apricot stones has the potential to replace im ported commercial activated carbons in gold adsorption processes.

关键词： gold recovery activated carbon hardshell of apricot stones adsorbent

Performance analysis of a tuned point absorber using SPH calm water and wave tank simulations

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Journal of Ocean Engineering and Science 2024年第5期9卷 409-436页

作者： Kaveh soleimani Mohammad Javad Ketabdari Department of Maritime Engineering Amirkabir University of TechnologyTehranIran

In this paper,two smoothed particle hydrodynamics(SPH)models,namely SPH-W and SPH-C were used to evaluate the motion response of a point absorber wave energy converter(WEC).In the SPH-W model,a long wave flume was constructed and a long simulation was performed to obtain the motion response of the *** the SPH-C model,the SPH method is only used to find the hydrodynamic coefficients of the device by analysing a few seconds of free-decaying motion of WEC in calm water in a much smaller numerical ***,these coefficients were inserted in the equation of motion of a heaving WEC that was solved using a 4th order Runge-Kutta(ODE45)solver in ***,the energy conservation property of the WCSPH model was examined through a standing wave benchmark ***,the wavepoint absorber interaction was *** the simulation time for SPH-C model is much smaller than that of SPH-W,it gave almost similar results for the motion response of *** two models were used to evaluate the effects of the control force and the draft of a cone-cylinder point absorber on its hydrodynamic *** results showed that compared to the effect of the supplementary inertia,changes in the draft of the WEC have a small influence on its hydrodynamic *** buoy draft has an inverse relationship with both added mass and damping ***,increasing the supplementary mass increases the added mass and decreases the hydrodynamic damping coefficients.

关键词： Point absorber Power take-off Control forces SPH wave tank test SPH calm water test DualSPHysics

Blockchain privacy and regulatory compliance:Towards a practical equilibrium

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Blockchain(Research and Applications) 2024年第1期5卷 1-9页

作者： Vitalik Buterin Jacob Illum Matthias Nadler Fabian Schär Ameen soleimani Ethereum Foundation Switzerland Chainalysis United States of America University of Basel Switzerland Privacy Pools United States of America

We study Privacy Pools,a novel smart contract-based privacy-enhancing *** protocol introduces a mechanism for users to reveal certain properties of their transaction without having to reveal the transaction *** core concept involves allowing users to publish a zero-knowledge proof,demonstrating that their funds(do not)originate from known(un-)lawful sources,without publicly revealing their entire transaction *** is achieved by proving membership in custom association sets,which are designed to demonstrate compliance with regulatory frameworks or social *** illustrate how this mechanism can create a separating equilibrium between compliant and non-compliant *** work describes the technical underpinnings,incentives,and broader implications of this mechanism,highlighting how Privacy Pools-like protocols can create more private yet compliant blockchain transactions.

关键词： Blockchain Privacy Regulation Smart contracts Zero-knowledge proofs

Analysis of CH_(4) and H_(2) Adsorption on Heterogeneous Shale Surfaces Using aMolecular Dynamics Approach

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Fluid Dynamics & Materials Processing 2024年第1期20卷 31-44页

作者： Surajudeen Sikiru Hassan soleimani Amir Rostami Mohammed Falalu Hamza Lukmon Owolabi Afolabi Centre of Subsurface Imaging(CSI) Universiti Teknologi PETRONASTronohPerakMalaysia Department of Geosciences Universiti Teknologi PETRONASBandar Seri IskandarTronohPerakMalaysia Department of Pure&Industrial Chemistry Faculty of Physical SciencesBayero University KanoKanoNigeria Department of Mechanical Engineering Engineering Institute of TechnologyMelbourne Campus VictoriaMelbourneAustralia

Determining the adsorption of shale gas on complex surfaces remains a challenge in molecular simulation *** essentially stem from the need to create a realistic shale structure model in terms of mineral heterogeneityand ***,precise characterization of the competitive adsorption of hydrogen andmethane in shale generally requires the experimental determination of the related adsorptive *** thisstudy,the adsorption of adsorbates,methane(CH_(4)),and hydrogen(H_(2))on heterogeneous shale surface modelsof Kaolinite,Orthoclase,Muscovite,Mica,C_(60),and Butane has been simulated in the frame of a moleculardynamic’s numerical *** results show that these behaviors are influenced by pressure and *** increasing the pressure from 500 to 2000 psi,the sorption effect for CH_(4)significantly increasesbut shows a decline at a certain stage(if compared to H_(2)).The research findings also indicate that raw shalehas a higher capacity to adsorb CH_(4)compared to ***,in shale,this difference is negligible.

关键词： Shale gas adsorption methane hydrogen molecular dynamic sorption

Naturally fractured hydrocarbon reservoir simulation by elastic fracture modeling

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Petroleum Science 2017年第2期14卷 286-301页

作者： Mehrdad soleimani Faculty of Mining Petroleum and Geophysics Shahrood University of Technology Shahrood Iran

Accurate fluid flow simulation in geologically complex reservoirs is of particular importance in construction of reservoir *** approaches in naturally fractured reservoir simulation involve use of unstructured grids or a structured grid coupled with locally unstructured grids and discrete fracture *** methods suffer from drawbacks such as lack of flexibility and of ease of *** this study,I combined fracture modeling by elastic gridding which improves flexibility,especially in complex *** proposed model revises conventional modeling fractures by hard rigid planes that do not change through *** is a dubious assumption,especially in reservoirs with a high production rate in the *** proposed elastic fracture modeling considers changes in fracture properties,shape and aperture through the *** strategy is only reliable for naturally fractured reservoirs with high fracture permeability and less permeable matrix and parallel fractures with less *** of elastic fracture modeling results with conventional modeling showed that these assumptions will cause production pressure to enlarge fracture apertures and change fracture shapes,which consequently results in lower production compared with what was previously *** is concluded that an elastic gridded model could better simulate reservoir performance.

关键词： Reservoir performance Discrete fracture model Naturally fractured reservoir History matching Elastic gridding

Ultrasonic irradiation and solvent effects on destabilization of colloidal suspensions of platinum nanoparticles

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Particuology 2014年第6期12卷 145-148页

作者： Alireza Salabat Shima soleimani Department of Chemistry Faculty of ScienceArak University

In this work,ultrasonic irradiation and destabilizer solvent were used for destabilizing colloidal platinum *** stabilized platinum nanoparticles were prepared in w/o microemulsion systems composed of sodium bis-（2-ethylhexyl） sulfosuccinate（AOT） and four different solvents,namely,cyclohexane,n-hexane,n-heptane,and *** recovery process of Pt nanoparticles from the colloidal systems was performed by exposing the colloidal samples to ultrasonic irradiation and applying various destabilizing *** of UV-visible spectra confirms that the quantity of Pt nanoparticles removed from the suspension depends on the length of time of the ultrasonic irradiation and the nature of the microemulsion oil phase.A critical time for the ultrasonic irradiation has been introduced for the phase separation of colloidal *** perform the solvent study,four destabilizer solvents,namely,dioxane,ethyl acetate,diethyl ether,and tetrahydrofuran,were used for breaking the colloidal suspension of platinum *** on the ’good solvent’ and ’poor solvent’ idea,it is verified that the effect of the destabilizer solvents on the aggregation process follows the following order：tetrahydrofuran 〉 ethyl acetate 〉dioxane〉 diethyl ether.

关键词： Colloid destabilization Ultrasonic irradiation Microemulsion Solvent effect

The impact of Persian oak (Quercus brantii Lindl.) on soil characteristics in a declining forest

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Journal of Forestry Research 2020年第6期31卷 2359-2366页

作者： Reza soleimani Ahmad Hosseini Crop and Horticultural Science Research Department Ilam Agricultural and Natural Resources Research and Education CenterAREEOIlamIran Forests and Rangelands Research Department Ilam Agricultural and Natural Resources Research and Education CenterAREEOIlamIran

Root activity has an important impact on soil development but we have little knowledge of the interaction of the root zone and soil genetic *** aim of this investigation was to study the interactions between soil chemical characteristics and root zone processes in a declining Persian oak forest(Quercus brantii Lindl.).A randomized complete block design was used to investigate the long-term eff ect of Persian oak on soil horizons,and the chemical and biological properties in two soil zones(under and outside the canopy).Results indicate that the rhizosphere zone had signifi cantly higher total organic carbon(TOC)than outside the canopy soil in the upper soil *** subsurface horizons,water-extractable organic carbon values were signifi cantly higher in rhizosphere than in non-rhizospheric *** biomass carbon(MBC)values in the rhizospheric zone decreased from the fi rst to the second *** MBC/TOC ratio indicated signifi-cant diff erences between the rhizosphere and soils outside of the canopy,with the exception of the subsurface *** the subsurface horizon of the rhizosphere,there was greater respiration of organic carbon(ΣCO 2/TOC)than in outside of canopy *** addition,root processes infl uenced pH,nitrogen fractions,and availability of phosphorus,potassium,iron,zinc and *** erences in soil characteristics between rhizospheric and non-rhizospheric zones were signifi cant in surface horizons due to higher root density than in deeper soil *** fi ndings indicate that Persian oak(Quercus brantii Lindl.)roots infl uenced the main soil chemical properties,even in calcareous soils.

关键词： Declining forest Persian oak Rhizosphere Soil horizons

Er^(3+) ion concentration effect on transient and steady-state behavior in Er^(3+):YAG crystal

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Chinese Physics B 2014年第10期23卷 248-253页

作者： Asadpour Seyyed Hossein Rahimpour soleimani H Department of Physics University of Guilan

The effect of Er3＋ ion concentration on transient and steady-state behavior in 45-nm Er3＋：YAG crystal is investigated. It is shown that by changing the signal field, the coherent field and the concentration of Er3＋ ions in the crystal, the absorption, dispersion, and group index of the weak probe field can be adjusted. Also, it is found that the probe absorption occurs in the presence of population inversion and probe amplification is obtained in the absence of population inversion.

关键词： Er3+ ion concentration absorption dispersion group index