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NIBU:An Integrated Framework for Representing the Relation Among Building Structure and Interior Utilities in Micro-Scale Environment

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Geo-Spatial Information Science 2011年第2期14卷 98-108页

作者： Ihab HIJAZI Sisi ZLATANOVA manfred EHLERS Institute for Geoinformatics and Remote Sensing (IGF) University of Osnabrueck OTB Research Institute for HousingUrban and Mobility Studies Delft University of Technology

This paper describes a framework for modeling interdependencies between different network systems and building *** provides an approach for the integrated analysis of interior building utilities by describing a framework to model and simulate infrastructure interdependencies and their complex *** is a graph-based spatial model that can support use cases such as providing the location and specifications of interior utilities to a technician who wants to perform a maintenance *** location could be needed for maintenance or replacement,or to investigate the result of damage to the building structure on another utility network,or to estimate the effect of different maintenance operations in different locations along utilities service *** model accounts for two important aspects:first,the relationship between interior utilities and building elements or spaces and second,the building hierarchy structure to which the utilities network is related.A proper hierarchy of the building is developed which supports the generation of human-oriented descriptions of interior utilities,where a method for partitions of large building element and spaces as well as a method to reference a network element to another building are *** connection of the different utilities network systems and buildings are generated using joints,which are based on a containment *** example is presented which shows the effectiveness of this approach for supporting maintenance operations,as well as the independences between the maintenance operation location and the other network *** paper presents the data model and explains the links with current 3D building model standards.

关键词： Building Information Model (BIM) building service system utility network graph city models

The effect of microclimate on wood decay is indirectly altered by tree species diversity in a litterbag study

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Journal of Plant Ecology 2017年第1期10卷 170-178页

作者： David Eichenberg Katherina Pietsch Christian Meister Wenyong Ding Mingjian Yu Christian wirth Institut für Spezielle Botanik und Funktionelle Biodiversität University of LeipzigJohannisallee 21-23Leipzig 04103Germany College of Life Sciences Zhejiang University866 Yuhangtang RoadHangzhou 310058China German Centre for Integrative Biodiversity Research(iDiv)Halle-Jena-Leipzig Deutscher Platz 5eLeipzig 04103Germany

Aims We studied the influence of tree species diversity on the dynamics of coarse wood decomposition in developing forest communities in a natural,topographically heterogeneous *** the litter bag technique,we investigated how and to which extent canopy tree species richness or the exclusion of mesoinvertebrates and macroinvertebrates affected wood decomposition in the light of natural variations in the *** compared the relative importance of the two aspects(experimental treatment versus microclimate)on wood decay rates using Schima superba as a standard *** Coarse woody debris(CWD)was deposited in litter bags with two different mesh sizes in a total of 134 plots along a gradient of canopy tree species richness(0-24 species).Wood decomposition was assessed at two consecutive time points,one and three years after deposition in the *** climatic conditions were assessed throughout the duration of the *** conditions were assessed both,directly in the field as well as indirectly via correlations with local *** used analysis of variance based approaches to assess the relative importance of the treatments(community tree species richness and macro invertebrate exclusion)and microclimatic conditions on wood *** Findings No direct influence of tree species richness on wood decay could be ***,the exclusion of macroinvertebrates significantly decreased wood decomposition *** addition,microclimatic conditions accounted for a substantial proportion of explained variance in the observed ***,wood decomposition was negatively affected by low mean temperatures and high variations in local humidity and ***,tree species richness as well as the respective species composition affected the presence of termites within forest ***,in turn,significantly increased the decay of *** strength of both,experimental treatment and microclimate increased with o

关键词： wood decomposition microclimate litter bag tree species diversity community composition

Human-as-a-security-sensor for harvesting threat intelligence

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Cybersecurity 2018年第1期1卷 652-666页

作者： manfred Vielberth Florian Menges Gunther Pernul Universitat Regensburg Universitatstr.3193053 RegensburgDEGermany

Humans are commonly seen as the weakest link in corporate information *** led to a lot of effort being put into security training and awareness campaigns,which resulted in employees being less likely the target of successful *** approaches,however,do not tap the full potential that can be gained through these *** the one hand,human perception offers an additional source of contextual information for detected incidents,on the other hand it serves as information source for incidents that may not be detectable by automated *** approaches only allow a text-based reporting of basic incident information.A structured recording of human delivered information that also provides compatibility with existing SIEM systems is still *** this work,we propose an approach,which allows humans to systematically report perceived anomalies or incidents in a structured *** approach furthermore supports the integration of such reports into analytics ***,we identify connecting points to SIEM systems,develop a taxonomy for structuring elements reportable by humans acting as a security sensor and develop a structured data format to record data delivered by humans.A prototypical human-as-a-security-sensor wizard applied to a real-world use-case shows our proof of concept.

关键词： Cyber threat intelligence Human awareness Human-as-a-security-sensor Security information and event management(SIEM)

Advancing Digital Earth:beyond the next generation

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International Journal of Digital Earth 2014年第1期7卷 3-16页

作者： manfred Ehlers Peter Woodgate Alessandro Annoni Sven Schade Institute for Geoinformatics and Remote Sensing University of Osnabru˝ckOsnabru˝ckGermany Cooperative Research Centre for Spatial Information Australia and New ZealandMelbourneAustralia Joint Research Centre European CommissionIspraItaly European Environment Agency CopenhagenDenmark

The Digital Earth(DE)movement is gaining *** of it is *** paper examines a number of recent developments including those in health sensors(Wearable Absence,Q-Sensor,and Guardian Angels)and systems frameworks(Gelernter’s Mirror Worlds,Virtual Australia,and New Zealand).Consideration is given to the implications of DE for citizens and on citizen science,including those of ethics.A suite of principles to guide the development of DE is proposed.

关键词： Digital Earth vision virtual spatial science Geomatics social science ethics

Pervasive geo-security - a lightweight triple-A approach to securing distributed geo-service infrastructures

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International Journal of Digital Earth 2014年第5期7卷 373-390页

作者： Bernd Resch Bernhard Schulz manfred Mittlboeck Thomas Heistracher Research Studio iSPACE Research Studios AustriaSalzburgAustria SENSEable City Laboratory Massachusetts Institute of TechnologyBostonMAUSA Department of Information Technology and Systems Management University of Applied SciencesSalzburgAustria

Security has recently become a major concern in distributed geo-infrastructures for spatial data ***,a lightweight approach for securing distributed low-power environments such as geo-sensor networks is *** first part of this article presents a survey of current security mechanisms for authentication and *** on this survey,a lightweight and scalable token-based security infrastructure was developed,which is tailored for use in distributed geo-web service *** developed security framework comprises dedicated components for authentication,rule-based authorisation and optimised storage and administration of access *** validation purposes,a prototypical implementation of the approach has been created.

关键词： pervasive security distributed geo-service infrastructures triple-A geo-authorisation standardised sensor networks service protection Geographic Information Systems(GIS) geoinformatics spatial data infrastructure Digital Earth Digital Earth Architecture

Diversity of wing patterns and abdomen-generated substrate sounds in 3 European scorpionfly species

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Insect Science 2015年第4期22卷 521-531页

作者： manfred Hartbauer Johannes Gepp Karin Hinteregger Stephan Koblmuller Institute of Zoology KarI-Franzens-University Graz Universitatsplatz 2 8010 Graz Institute for Nature Conservation Herdergasse 3 8010 Graz Austria

In the genus Panorpa （Insecta： Mecoptera）, also known as scorpionflies, pre- mating behavior includes repeated sequences of slow wing movements （waving, fanning, flagging） which are accompanied by rapid abdomen vibrations that generate substantial substrate-borne sound. It is still unknown whether wing patterns or vibratory signals contain information about species identity, sex and/or the quality of potential mating part- ners. Besides species-specific pheromones, these multimodal signals may be of particular importance for the maintenance of reproductive isolation in sympatrically occurring scor- pionfly species. Here, we analyzed phyologenetic relationships among, and the pattern of forewings as well as substrate-borne sound in 3 different sympatric Central-European scorpionfly species （P communis, P germanica, and P alpina）. Divergence time estimates, based on 879 bp of the mitochondrial COI gene, indicate longstanding separate evolu- tionary histories for the studied Panorpa species. Morphological analysis revealed that wing length as an indicator of body size increased in the following order： P alpina 〈 P. germanica 〈 P. communis. Individuals can be assigned to the correct species and sex with high accuracy just by evaluation of the number of dark spots and the proportion of wing pigmentation. Despite high variability of interpulse period at an individual level, across species analysis revealed a positive correlation of average interpulse period as well as mean signal amplitude with forewing length. These results suggest wing patterns, but less likely vibratory signals, to contain information about species identity. Furthermore, receivers may be able to estimate the body size of a signaler solely on the basis of substrate-borne sound.

关键词： courtship signals laser vibrometry phylogeny species recognition substrate-borne sound wing pattern

Selective Suspension in Aqueous Sodium Dodecyl Sulfate According to Electronic Structure Type Allows Simple Separation of Metallic from Semiconducting Single-Walled Carbon Nanotubes

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Nano Research 2009年第8期2卷 599-606页

作者： Kai Moshammer Frank Hennrich manfred M.Kappes Forschungszentrum Karlsruhe Institut für NanotechnologieD-76021 KarlsruheGermany Institut für Physikalische Chemie Universität KarlsruheD-76128 KarlsruheGermany

Both density gradient centrifugation and gel electrophoresis have been reported to allow high throughput separation of metallic from semiconducting single-walled carbon nanotubes(SWNTs)when using aqueous sodium dodecyl sulphate(SDS)*** show here that both methods rely on an initial dispersion-by-sonication step,which is already selective with respect to electronic structure *** corresponding aqueous SDS“starting”suspensions obtained after sonication and purifi cation by simple centrifugation(70,000 g,1 h)contain semiconducting SWNTs primarily in the form of small bundles whereas metallic SWNTs are predominantly suspended as individual *** gradient centrifugation then separates the bundles from the individual tubes on the basis of differences in their overall buoyant *** electrophoresis separates the longer bundles from the shorter individual tubes on the basis of their different *** also demonstrate that such starting suspensions can be fractionated according to electronic structure type by even simpler techniques such as size exclusion chromatography or gel fi ltration,thus opening the way for simple scale-up.

关键词： Single-walled carbon nanotubes metallic–semiconducting separation electrophoresis density gradient centrifugation size exclusion chromatography

Role of glycosylation in TGF-β signaling and epithelial-to-mesenchymal transition in cancer

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Protein & Cell 2021年第2期12卷 89-106页

作者： Jing Zhang Peter ten Dijke manfred Wuhrer Tao Zhang Oncode Institute and Cell Chemical Biology Leiden University Medical Center2300 RC LeidenThe Netherlands Center for Proteomics and Metabolomics Leiden University Medical CenterLeidenThe Netherlands

Glycosylation is a common posttranslational modification on membrane-associated and secreted proteins that is of pivotal importance for regulating cell *** glycosylation can lead to uncontrolled cell proliferation,cell-matrix interactions,migration and differentiation,and has been shown to be involved in cancer and other *** epithelial-to-mesenchymal transition is a key step in the metastatic process by which cancer cells gain the ability to invade tissues and extravasate into the *** cellular transformation process,which is associated by morphological change,loss of epithelial traits and gain of mesenchymal markers,is triggered by the secreted cytokine transforming growth factor-β(TGF-β).TGF-βbioactivity is carefully regulated,and its effects on cells are mediated by its receptors on the cell *** this review,we first provide a brief overview of major types of glycans,namely,N-glycans,O-glycans,glycosphingolipids and glycosaminoglycans that are involved in cancer ***,we summarize studies on how the glycosylation of TGF-βsignaling components regulates TGF-βsecretion,bioavailability and TGF-βreceptor ***,we review glycosylation changes associated with TGF-β-induced epithelial-to-mesenchymal transition in *** and understanding the mechanisms by which glycosylation affects TGF-βsignaling and downstream biological responses will facilitate the identification of glycans as biomarkers and enable novel therapeutic approaches.

关键词： cancer epithelial-to-mesenchymal transition glycosphingolipids N-glycosylation Oglycosylation transforming growth factor-β

Monitoring dynamics of defects and single Fe atoms in N-functionalized few-layer graphene by in situ temperature programmed scanning transmission electron microscopy

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Journal of Energy Chemistry 2022年第1期31卷 520-530,I0014页

作者： Rosa Arrigo Takeo Sasaki June Callison Diego Gianolio manfred Erwin Schuster School of Science Engineering and EnvironmentUniversity of SalfordManchester M54WTUK Diamond Light Source Harwell Science and Innovation CampusDidcot 0X1/ODEUK JEOL UK Ltd.JEOL House 1-2 Silver CourtWatchmeadWelwyn Garden CityHerts AL71LTUK Department of Chemistry University College London20 Gordon StreetLondon WC1H OAJUK UK Catalysis Hub Research Complex at Harwell(RCaH)Rutherford Appleton LaboratoryHarwell Oxon 0X11 OFAUK Johnson Matthey Technology Centre Reading RG49NH.UK

In this study,we aim to contribute an understanding of the pathway of formation of Fe species during top-down synthesis of dispersed Fe on N-functionalized few layer graphene,widely used in *** use X-ray absorption spectroscopy to determine the electronic structure and coordination geometry of the Fe species and in situ high angle annular dark field scanning transmission electron microscopy combined with atomic resolved electron energy loss spectroscopy to localize these,identify their chemical configuration and monitor their dynamics during thermal *** show the high mobility of peripheral Fe atoms,first diffusing rapidly at the trims of the graphene layers and at temperatures as high as 573 K,diffusing from the edge planes towards in-plane locations of the graphene layers forming three-,four-coordinated metal sites and more complexes polynuclear Fe *** process occurs via bond C-C breaking which partially reduces the extension of the graphene ***,the vast majority of Fe is segregated as a metal *** dynamic interconversion depends on the structural details of the surrounding graphitic environment in which these are formed as well as the Fe loading.N species appear stabilizing isolated and polynuclear Fe species even at temperatures as high as 873 *** significance of our results lies on the fact that single Fe atoms in graphene are highly mobile and therefore a structural description of the electroactive sites as such is insufficient and more complex species might be more relevant,especially in the case of multielectron transfer *** we provide the experimental evidence of the formation of these polynuclear Fe-N sites and their structural characteristics.

关键词： HAADF-STEM Single Fe atom sites N-doped Few-layer graphene Dinuclear Fe species