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The Journal of Biomedical Research 2012年第5期26卷 371-371页

作者： Gouri Sankar Bhunia manas Ranjan Dikhit Shreekant Kesari Ganesh Chandra Sahoo Pradeep das Rajendra Memorial Research Institute of Medical Sciences(ICMR) AgamkuanPatnaBihar 800007India

The author would like to inform the readers that the correct form of title ＂Role of remote sensing, geographic bioinformatics system and bioinformatics in kala-azar epidemiology＂ , content in ab-stract ＂The computational approaches like remote sensing, geographic information system （GIS） and bioinformatics are the key re-sources for the detection and distribution of vectors, patterns, ecologi- cal and environmental factors and genomic and proteomic analysis.＂, and keyword ＂geographical bioinformatics systems （GIS）＂ should be read as follows： title ＂Role of remote sensing, geographical bioinformation system and bioinformatics in kala-azar epidemiology＂, content in abstract ＂The com-putational approaches like remote sensing, geographical information system （GIS） and bioinformat-ics are the key re-sources for the detection and distribution of vectors, patterns, ecological and envi-ronmental factors and genomic and proteomic analysis.＂, and keyword ＂geographical bioinformation system （GIS）＂.

关键词： originally published as J Biomed Res 2011,25 GIS Corrigendum to Role of remote sensing,geographic bioinformatics system and bioinformatics in kala-azar epidemiology

Pattern of injuries due to wild animal attack among patients presenting to the emergency department:A retrospective observational study

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Chinese Journal of Traumatology 2021年第6期24卷 383-388页

作者： Pradeep Kumar Singh S Manwar Ali Rakesh Vadakkethil Radhakrishnan Chitta Ranjan Mohanty manas Ranjan Sahu Bishnu Prasad Patro Ijas MS Susant Kumar Panda Department of General Surgery All India Institute of Medical SciencesBhubaneswar751019India College of Nursing All India Institute of Medical SciencesBhubaneswar751019India Department of Trauma and Emergency All India Institute of Medical SciencesBhubaneswar751019India Department of Forensic Medicine and Toxicology All India Institute of Medical SciencesBhubaneswar751019India Department of Orthopedics All India Institute of Medical SciencesBhubaneswar751019India Department of General Surgery District Head Quarter HospitalAngulOdish1759122India

Purpose:The human-wildlife conflicts(HWCs)causing nuisances and injuries are becoming a growing public health concern over recent years *** aimed to study the demographic profile,mode of injury,pattern of injury,and outcome of wild animal attack victims presented to the emergency ***:This retrospective cross-sectional study was conducted in the emergency department of a tertiary-care hospital in Eastern *** were retrieved from the medical records from May 2017 to May *** of all ages and genders attacked by wild animals and secondary injuries were included in this *** with incomplete data,injuries due to the attack of stray and domestic animals and trauma due to other causes were *** profile,mode of injury,the pattern of injury,injury severity score(ISS),radiological pattern,and outcome were *** analysis with R(version 3.6.1.)was ***:A total of 411 wild animal attack victims were studied,of which 374(90.9%)were snakebite injuries and 37(9.1%)were wild mammalian(WM)attack *** mean age of WM attack victims was 46 years,and the male-to-female ratio was 4:*** attack injury(40.5%)was the most common WM attack injury *** WM attacks(43.2%)occurred between 4:00 *** 8:00 *** median ISS was 18.5(13-28),where 54.2%of patients had polytrauma(ISS>15).Elephant attack was associated with a higher ISS,but the difference was not significant compared to other animal types(p=0.2).Blunt trauma was common pattern of injury in the elephant attack injury *** and soft tissue injuries were common patterns in other animal *** snakebites,neurotoxic was the most common type(55.4%),and lower extremity was the most common site ***:The young male population is the major victim of HWCs;and elephant is the most common animal *** is a need to design scientifically sound preventive strategies for HWCs and to strengthen t

关键词： Wild animal Injury severity score Elephant Wild boar Polytrauma

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印度露天采矿的回填要求和制约因素

产业与环境 2002年第1期24卷 72-74页

作者： manas K.Mukhopadhyay I.N.Sinha 蔡笛 Manager MECON Ltd. N-162 Shyamali Colony Doranda Ranchi 834002 India Assistant Professor Centre of Mining Environment Indian School of Mines Dhanbad India

印度的大多数采矿活动都发生在生态敏感地区．本文讨论了一项回填(即用挖出来的物质填矿井)研究计划的结果．在一些情况下,由于技术限制,回填法的使用不得不被部分或全部放弃．也有许多费用方面的考虑．制定一条国家改造采矿用地战略是... 详细信息

印度的大多数采矿活动都发生在生态敏感地区．本文讨论了一项回填(即用挖出来的物质填矿井)研究计划的结果．在一些情况下,由于技术限制,回填法的使用不得不被部分或全部放弃．也有许多费用方面的考虑．制定一条国家改造采矿用地战略是最根本的策略．

关键词：印度露天采矿回填制约因素土地退化

DCP和液体NR对NR/PS共混体物理性能的影响

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橡胶参考资料 1998年第8期28卷 23-29页

作者： Z.manas I.Abdullah S.Ahmad 税珺琰

有关橡胶-塑料共混体的研究已有许多文献报道。由简单的加工方法获得的橡塑共混体具有宽广的性能,因此,从工艺上说它们在工业应用中是相当重要的。这种材料被称做热塑性橡胶,即它们在适当的加工温度下可以象塑料一样模制。

关键词：液体橡胶天然橡胶共混物理性能 DCP 聚苯乙烯

A Holistic Approach to Enhance FRCS General Surgery Examination Training Using Adult Learning Model: A Non-Profit Initiative

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Surgical Science 2023年第8期14卷 565-574页

作者： Rahul Winayak Sanjay V. Joshi Goran Ahmed Anne O’Neill Ishy Gurung Muhammad Nadeem Muhammed Alwahid Sudeendra Doddi manas Kumar Dube Ahmad Mirza Rishabha D. Sharma Bristol Medical School University of Bristol Bristol UK Medway Maritime Hospital Gillingham Kent UK Frimley Park Hospital Portsmouth Road Camberley UK University Hospitals Plymouth NHS Trust Plymouth UK Northern Devon Healthcare NHS Trust Barnstaple UK Yeovil District Hospital NHS Foundation Trust Yeovil UK Inverclyde Royal Hospital Greenock Scotland UK Princes Royal University Hospital Orpington UK Sherwood Forest Hospitals NHS Foundation Trust Mansfield UK Augusta University Medical Center Augusta GA USA

Objectives: To evaluate the impact of adult learning and simulation-based learning (SBL) on surgical trainees’ learning experiences and Fellowship of the Royal College of Surgeons (FRCS) Section 2 General Surgery examination pass rate. Methods: This was a cross-sequential study involving 148 surgical candidates (72 UK trainees, 75 non-UK trainees) who had attended our revision course (Phoenix FRCS Course) from June 2017 until 2023. Each course comprised a two-day weekend preparation with dedicated sections for clinical, viva, and academic reading, incorporating SBL as its key learning style. We maintained a prospective database of candidate and course details, examination results, and feedback since the course inception. Results: We found that 97% of candidates passed the FRCS examination after their first attempt. The course was attended once by 89% of candidates, and only 3 of the 148 candidates exhausted all four attempts at the examination. Candidate feedback for the course and its style of learning was positive, with simulation-based table viva sessions and virtual clinical sessions proving the most popular learning sessions (95% and 80% of candidates attending courses run in December 2017, April 2018, and May 2021 rated them “Excellent” respectively). Conclusions: The course is centered around shared adult learning and mindfulness tools to encourage candidates to learn from each other and develop confidence and mastery in all domains of surgical practice. These methods have been shown to be effective in achieving high success rates in the Intercollegiate and International FRCS examinations for UK and overseas surgeons.

关键词： Simulation-Based Learning (SBL) Adult Learning Mindfulness Tools FRCS Examination Interleaving

Pregnancy and inflammatory bowel diseases: Current perspectives, risks and patient management

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World Journal of Gastrointestinal Pharmacology and Therapeutics 2015年第4期6卷 156-171页

作者： Pegah Hosseini-Carroll Monica Mutyala Abhishek Seth Shaheen Nageeb Demiana Soliman Moheb Boktor Ankur Sheth Jonathon Chapman James Morris Paul Jordan Kenneth manas Felix Becker Jonathan Steven Alexander Department of Medicine Section of Gastroenterology and Hepatology Louisiana State University Health Sciences Center Department of Molecular and Cellular Physiology Louisiana State University Health Sciences Center Digestive Health Center of Louisiana Department of General and Visceral Surgery

Inflammatory bowel diseases(IBD) are chronic idiopathic inflammatory conditions characterized by relapsing and remitting episodes of inflammation which can affect several different regions of the gastrointestinal tract, but also shows extra-intestinal manifestations. IBD is most frequently diagnosed during peak female reproductive years, with 25% of women with IBD conceiving after their diagnosis. While IBD therapy has improved dramatically with enhanced surveillance and more abundant and powerful treatment options, IBD disease can have important effects on pregnancy and presents several challenges for maintaining optimal outcomes for mothers with IBD and the developing fetus/neonate. Women with IBD, the medical team treating them(both gastroenterologists and obstetricians/gynecologists) must often make highly complicated choices regarding conception, pregnancy, and post-natal care(particularly breastfeeding) related to their choice of treatment options at different phases of pregnancy as well as post-partum. This current review discusses current concerns and recommendations for pregnancy duringIBD and is intended for gastroenterologists, general practitioners and IBD patients intending to become,(or already) pregnant, and their families. We have addressed patterns of IBD inheritance, effects of IBD on fertility and conception(in both men and women), the effects of IBD disease activity on maintenance of pregnancy and outcomes, risks of diagnostic procedures during pregnancy and potential risks and complications associated with different classes of IBD therapeutics. We also have evaluated the clinical experience using "top-down" care with biologics, which is currently the standard care at our institution. Post-partum care and breastfeeding recommendations are also addressed.

关键词： Inflammatory bowel diseases Pregnancy Biologics Br

聚集体结构和基质对炭黑聚集体分散行为的影响

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橡胶参考资料 1996年第12期26卷 31-34页

作者： Qi Li D.LFeke I.manas-Zloczower 文闽军

前言炭黑是橡胶和塑料工业最常用的一种填料。填充聚合物的机械性能、光学性能及电性能在很大程度上依赖于炭黑分散的好坏。分散过程与炭黑聚集体的结构和形态、所施加的流动场的几何形状及强度以及炭黑粒子的堆砌和内聚强度有直接关系... 详细信息

前言炭黑是橡胶和塑料工业最常用的一种填料。填充聚合物的机械性能、光学性能及电性能在很大程度上依赖于炭黑分散的好坏。分散过程与炭黑聚集体的结构和形态、所施加的流动场的几何形状及强度以及炭黑粒子的堆砌和内聚强度有直接关系。本文。

关键词：炭黑聚集体炭黑粒子分散行为聚集体结构高结构炭黑低结构炭黑内聚力侵蚀破坏分散过程基质

A Study of Prevalence of Diabetes and Prediabetes in Patients of Non-Alcoholic Fatty Liver Disease and the Impact of Diabetes on Liver Histology in Coastal Eastern India

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Journal of Diabetes Mellitus 2014年第4期4卷 290-296页

作者： Shivaram Prasad Singh Ayaskanta Singh Girish Kumar Pati Bijay Misra Debasis Misra Sanjib Kumar Kar manas Kumar Panigrahi Chudamani Meher Omprakash Agrawal Niranjan Rout Kaumudi Pattnaik Pallavi Bhuyan Amarendra Mohapatra Department of Gastroenterology S. C. B. Medical College Cuttack India Department of Radiology Beam Diagnostics Centre Cuttack India Department of Oncopathology A. H. Regional Cancer Center Cuttack India Department of Pathology S. C. B. Medical College Cuttack India Regional Medical Research Centre Bhubaneswar India

Background and Objectives: Non-alcoholic fatty liver disease (NAFLD) is more common in diabetic patients. There are limited studies on clinical, biochemical and histological features of NAFLD patients who are diabetic. The aim of the study was to determine the prevalence of diabetes and prediabetes in a cohort of NAFLD patients and to compare anthropometry, biochemical and metabolic parameters and hepatic histology of diabetic NAFLD patients with non-diabetic NAFLD patients. Methods: 515 consecutive NAFLD patients diagnosed by abdominal ultrasound and 100 healthy controls were subjected to detailed anthropometric measurements and biochemical assays including blood sugars, LFT, lipid profile and HOMA. Diabetes and prediabetes were defined according to WHO criteria. Patients were categorized and compared according to the presence or absence of diabetes. Liver biopsy was performed in 240 NAFLD patients and the liver histology was also compared between the two groups. Statistical analysis was performed on SPSS 16. Results: 124 out of the 515 (24.08%) NAFLD patients were diabetics, 118 out of 515 (22.9%) were pre-diabetics, while only 3 out of 100 controls had impaired glucose tolerance. Diabetic patients were older. NAFLD patients with diabetes had significantly higher waist circumference [98.02 ± 12.01 vs 93.89 ± 8.8, p = 0.000] as compared to the NAFLD patients without diabetes. Fasting blood sugar [124 ± 46.3 vs 90.8 ± 10.2, p = 0.000], triglyceride level [218.4 ± 17.6 vs 192 ± 9, p = 0.03] and HOMA-IR [2.6 ± 0.36 vs 1.84 ± 0.2, p < 0.001] were significantly higher in NAFLD-diabetes group. Hypertension [35% vs 11.7%, p = 0.000] was commoner in diabetic NAFLD patients. Histopathology in the diabetic patients revealed steatosis alone in 34.2% cases, borderline NASH in 31.4% and definite NASH in 34.2%. Fatty change alone was noted in 16.5% cases, borderline NASH in 34.1%, while 49% had definite NASH on liver biopsy of NAFLD patients without diabetes. Fibrosis was noted

关键词： Fatty Liver Diabetes Prediabetes Liver Histology Insulin Resistance Steatohepatitis

Gut sterilization in experimental colitis leukocyte mediated colon injury, and effects on angiogenesis/lymphangiogenesis

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Open Journal of Gastroenterology 2013年第1期3卷 12-24页

作者： Mihir Patel Justin Olinde Allison Tatum Chaitanya V. Ganta Walter E. Cromer Ankur R. Sheth Merilyn H. Jennings J. Michael Mathis Traci Testerman Paul A. Jordan Kenneth manas Christopher P. Monceaux J. Steven Alexander Department of Cellular Biology and Anatomy LSU Health Shreveport Shreveport USA Department of Gastroenterology and Hepatology LSU Health Shreveport Shreveport USA Department of Microbiology and Immunology LSU Health Shreveport Shreveport USA Department of Molecular and Cellular Physiology LSU Health Shreveport Shreveport USA

Inappropriate responses to normal commensal bacteria trigger immune activation in both inflammatory bowel disease and experimental colitis. How gut flora contribute to the pathogenesis of inflammatory bowel disease is unclear, but may involve entrapment of leukocytes and remodeling of the vascular system. Here we evaluated how the progression and tissue remodeling in experimental colitis differ in a germ- free model of mouse colitis. Four treatment groups were used: control, antibiotic-treated (ABX), dextran sulfate colitis (DSS) and DSS pre- and co-treated with antibiotics (DSS + ABX). In days 0 - 3 of the study, germ-free mice received antibiotics (vancomycin, neomycin, and metronidazole). During the next 11 days, antibiotics were continued and DSS (3%) added to “colitis” groups. Disease activity, weight, stool form and blood were monitored daily. Mice were sacrificed and tissue samples harvested. Histopathological scores in controls (0.00) and in ABX (1.0+/–0.81) were significantly (p –0). Extents of injury, inflammation and crypt damage were all improved in DSS + ABX. The Disease Activity Index score (day 11) was significantly worse in the DSS group compared to the DSS + ABX group. Stool blood and form scores were also significantly improved among these groups. Importantly, myeloper- oxidase was significantly reduced in DSS + ABX, indicating that neutrophil infiltration was blocked. Colitis was associated with an increase in blood and lymphatic vessels;both of these events were also significantly reduced by gut sterilization. Our experiment shows that clinical and histopathological severity of colitis was significantly worse in the DSS colitis group compared to the DSS + ABX group, supporting the hypothesis that development of IBD is likely to be less severe with appropriate antibiotic treatment. In particular, gut sterilization effectively reduces leuko- cyte-dependent (PMN) injury to improve outcomes and may be an important target for therapy.

关键词： Crohn’s Disease Antibiotics Myeloperoxidase Lymphatics Angiogenesis

<i>Helicobacter</i>infection decreases basal colon inflammation, but increases disease activity in experimental IBD

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Open Journal of Gastroenterology 2013年第3期3卷 177-189页

作者： Christopher P. Monceaux Traci L. Testerman Moheb Boktor Paul Jordan Patrick Adegboyega David J. McGee Merilyn H. Jennings Courtney P. Parker Shelly Gupta Ping Yi Vijay C. Ganta Haidy Galous Kenneth manas J. Steven Alexander Department of Gastroenterology and Hepatology LSU Health Shreveport Shreveport USA Department of Microbiology and Immunology LSU Health Shreveport Shreveport USA Department of Molecular and Cellular Physiology LSU Health Shreveport Shreveport USA Department of Pathology LSU Health Shreveport Shreveport USA

Background: Helicobacter species are best known for their roles in the pathology of gastritis;however, several Helicobacter species also colonize the intestine, and less is known about effects of Helicobacter on the development of intestinal inflammation. To evaluate contributions of Helicobacter in inflammatory bowel disease, we investigated whether and how pre-existing intestinal colonization would affect disease severity and biomarkers of inflammation in experimental IBD. Materials and Methods: Mice were infected with H. muridarum 2 weeks prior to induction of colitis mediated by 3% dextran sulfate (DSS). Disease activity index, stool blood and consistency, colon length, myeloperoxidase, histopathology, blood and lymphatic vessels, and numbers of dilated mucosal crypts were measured in control, DSS-only, H. muridarum-infected, and H. muridarum-infected + DSS mice. Results: Prior to DSS challenge, H. muridarum-infected mice showed little distal gut injury by several indices of colon inflammation with decreased blood vessel density in the submucosa, and lower lymphatic density in the mucosa and submucosa. However, after DSS colitis, H. muridarum-infected mice exhibited significantly greater disease. Weight change, stool bleeding, diarrhea, and angiogenesis were all increased in H. muridarum-infected mice in DSS colitis compared to DSS controls. Conclusions: Our data show that Helicobacter colonization of the intestine, unlike that of the stomach, lowers basal gut inflammatory scores, but increases disease activity and inflammation in an acute colitis model. Intestinal Helicobacter infection may therefore represent a significant sub-clinical factor which predisposes the gut to inflammatory injury.

关键词： Helicobacter Colon Lymphatics Crohn’s Disease Ulcerative Colitis