检索结果-南通市图书馆

Effectiveness of hepatitis B virus vaccination program in Egypt:Multicenter national project

World Journal of hepatology 2015年第22期7卷 2418-2426页

作者： Iman I Salama Samia M Sami Zeinab Nabil Ahmed Said manal h El-Sayed Lobna A El Etreby Thanaa M Rabah Dalia M Elmosalami Amany T Abdel hamid Somaia I Salama Aida M Abdel Mohsen hanaa M Emam Safaa M Elserougy Amal I hassanain Naglaa F Abd Alhalim Fatma A Shaaban Samia A hemeda Nihad A Ibrahim Ammal M Metwally Community Medicine Research Department National Research Center Child health Department National Research Center Micro--biology and Immunology Department Faculty of Medicine (for girls)Al-Azhar University Pediatrics Department Faculty of MedicineAin-Shams University Dermatology and Venereology Department National Research Center Environmental and Occupational Medicine Department National Research Center

AIM:To assess the effectiveness of hepatitis B virus(hBV) vaccination program among fully vaccinated ***:A national community based crosssectional study was carried out in 6 governorates representing Egypt. A total of 3600 children aged from 9 mo to 16 years who were fully vaccinated with hBV vaccine during infancy were recruited. Face to face interviews were carried out and sera were evaluated for hepatitis B surface antigen(hBsA g),anti-hBV core antibodies(total) and quantitative detection of hepatitis B surface antibody using enzyme linked immunoassays techniques. Samples positive to hBs Ag/anti-hBV core antibodies were subjected to quantitative hBV-DNA detection by real time polymerase chain reaction with 3.8 IU/L detection limit. RESULTS:Sero-protection was detected among 2059 children(57.2%) with geometric mean titers 75.4 ± 3.6 IU/L compared to 3.1 ± 2.1 IU/L among nonseroprotected children. Multivariate logistic analysis revealed that older age and female gender were the significant predicting variables for having non seroprotective level,with adjusted odds ratio 3.3,9.1and 14.2 among children aged 5 to hose h P hBs Ag was positive in 0.11% and breakthrough infection was 0.36% and 0.39% depending on positivity of anti-hBc and DNA detection respectively. The prevalence of hBV infection was significantly higher among children aged ≥ 7 years(0.59%) compared to 0.07% among younger children with odds ratio equal to 8.4(95%CI:1.1-64.2) and P higher among girls(0.48%) than boys(0.29%) with P > 0.05. C ON C LU S I ON :T he E gy pt ian c ompuls or y h B V vaccination program provides adequate protection. Occult hBV infection exists among apparently healthy vaccinated children. Adherence to infection control measures is mandatory.

关键词： hepatitis B virus Immunization Seroprotection Brea

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

In vitro inhibitory effects on a-glucosidase and a-amylase level and antioxidant potential of seeds of Phoenix dactylifera L.

引用

Asian Pacific Journal of Tropical Biomedicine 2016年第4期6卷 322-329页

作者： Shah Alam Khan Amira Rashid Al Kiyumi manal Saif Al Sheidi Tagreed Salim Al Khusaibi Noura Mohammed Al Shehhi Tanveer Alam Department of Pharmacy Oman Medical College Oman Medicinal Plants & Marine Natural Products University of Nizwa

Objective:To evaluate and compare the antioxidant activity,total phenolic contents(TPCs) and in vitro antidiabetic activity of various pits extracts obtained from five Omani date ***:Sun-dried mature fruits of five Omani date varieties,namely,Fardh,Naghal,Khalas,Khinazi and Khasab were purchased from the local market in Muscat,Oman in the month of September *** seed extracts ***,ethanol,methanol and acetone were prepared for each date variety and their antioxidant activities were investigated by 1,1-diphenyl-2-picrylhydrazyl,hydrogen peroxide scavenging method and reducing power assay method,*** vitro antidiabetic activity of the date pit extracts was evaluated by measuring their inhibitory effect on a-glucosidase and aamylase *** were also quantified ***:The results indicated that TPC of date seeds was solvent ***,ethanol and methanol were found to be significantly better solvents than water in extracting phenolic compounds from the date *** extracts exhibited moderate to good in vitro antioxidant activity and increased reducing *** all date pit extracts,water extract exhibited significant in vitro antidiabetic activity in comparison to standard drug,***:The present study confirms that disposed waste of Omani dates is a rich source of dietary antioxidant because of its high *** pits due to their inhibitory effects on a-glucosidase and a-amylase level could be used as a monotherapy along with an appropriate diabetic diet and exercise or might be in conjunction with antidiabetic therapy to manage and prevent progression of diabetes.

关键词： Phoenix dactylifera L. Antioxidant In vitro antidiabetic activity Date pits

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：