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Chewing gum for declining ileus and accelerating gastrointestinal recovery after appendectomy

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Frontiers of Nursing 2018年第4期5卷 277-284页

作者： manal Hamed Mahmoud Safaa Hussein mohammad Medical-Surgical Nursing Faculty of Nursing Benha University Medical-Surgical Nursing Faculty of Nursing Zagazig University

Objective: Ileus usually occurs after abdominal surgery and is allied with complication and delays recovery. It is hypothesized that chewing gum reduces postoperative ileus by improving early recovery of gastrointestinal function. This study aimed to explore whether chewing gum after appendectomy accelerates the recovery of gastrointestinal ***: Randomized control trial was used in this study. This study was conducted in the General Surgery Department at Zagazig University Hospital. A total of 240 patients undergoing appendectomy were involved in this study; they were divided into the chewing sugar-free gum group(120) and the control group(120). Two tools were utilized in this study. Tool I: Structured Interviewing Schedule: part 1: assessment of personnel characteristics. Part 2: assessment of anthropometric measurements of the studied subjects as well as pre-and intraoperative indicators of them. Tool II: postoperative assessment sheet: assessed postoperative parameters of the intestinal function, occurrence of postoperative ileus, and related symptoms were assessed among studied ***: There were highly significant statistical differences in the time of resumption of gastrointestinal functions and postoperative ileus symptoms between the two groups(P<0.001), which was significantly shorter in the chewing gum group compared to the control ***: The use of chewing gum is a useful and cheap method that can be employed to cut down the time to recover and accelerate normalization of gastrointestinal function. Chewing sugar-free gum after abdominal surgery is recommended to be added to the protocol of nursing care in the surgery units as well as its involvement in the nursing curriculum.

关键词： appendectomy chewing gum gastrointestinal recovery ileus

Calcium channel α2δ1 subunit as a novel biomarker for diagnosis of hepatocellular carcinoma

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Cancer Biology & Medicine 2018年第1期15卷 52-60页

作者： Sana Amhimmid Badr Maryan Waheeb Fahmi manal Mahmoud Nomir Mamdouh mohammad El-Shishtawy Biochemistry Department Faculty of Pharmacy Medical Oncology Unit Internal Medicine DepartmentFaculty of Medicine Clinical Pathology Department Students Hospital Mansoura University

Objective:Hepatocellular carcinoma(HCC)is the fifth most common malignancy *** identification of new simple,inexpensive and highly accurate markers for HCC diagnosis and screening is *** case-control study evaluates the role of annexin A2 and voltage-gated calcium channelsα2δ1 subunit as serum biomarkers for HCC ***:The study comprised three groups:group 1,50 patients with an initial diagnosis of HCC associated with chronic hepatitis C virus infection;group 2,25 patients diagnosed with chronic hepatitis C virus infection and cirrhosis without any evidence of HCC;and group 3,15 healthy *** participants were subjected to clinical and laboratory investigations,and radiological *** serum levels of alpha-fetoprotein(AFP),annexin A2,and theα2δ1 subunit were evaluated by using ELISA ***:The serum levels of annexin A2 significantly increased in patients with HCC(10.4±2.5 ng/m L;P<0.001)or with cirrhosis(9.31±1.8 ng/m L;P<0.001)comparing to that of healthy controls(0.296±0.09 ng/m L).However,there was no significant difference in serum annexin A2 levels in patients with HCC comparing to those with ***α2δ1 subunit significantly increased in patients with HCC(20.12±3.7 ng/m L)comparing to that in patients with cirrhosis(10.41±3.4 ng/m L,P<0.001)and healthy controls(10.2±2.9 ng/m L,P<0.001).Conclusions:The serumα2δ1 subunit may function as a new biomarker for HCC ***,serum annexin A2 has low diagnostic value as an HCC marker,especially in patients with underlying cirrhosis.

关键词： Hepatocellular carcinoma tumor initiation cell marker α2δ1 subunit annexin A2 alpha-fetoprotein

Intelligent Smart Grid Stability Predictive Model for Cyber-Physical Energy Systems

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Computer Systems Science & Engineering 2023年第2期44卷 1219-1231页

作者： Ashit Kumar Dutta manal Al Faraj Yasser Albagory mohammad zeid M Alzamil Abdul Rahaman Wahab Sait Department of Computer Science and Information Systems College of Applied SciencesAlMaarefa UniversityAd DiriyahRiyadh13713Kingdom of Saudi Arabia Department of Computer Engineering College of Computers and Information TechnologyTaif UniversityTaif21944Kingdom of Saudi Arabia Department of Archives and Communication King Faisal UniversityAl AhsaHofuf31982Kingdom of Saudi Arabia

A cyber physical energy system(CPES)involves a combination of pro-cessing,network,and physical *** smart grid plays a vital role in the CPES model where information technology(IT)can be related to the physical *** the same time,the machine learning(ML)modelsﬁnd useful for the smart grids integrated into the CPES for effective decision ***,the smart grids using ML and deep learning(DL)models are anticipated to lessen the requirement of placing many power plants for electricity *** this aspect,this study designs optimal multi-head attention based bidirectional long short term memory(OMHA-MBLSTM)technique for smart grid stability predic-tion in *** proposed OMHA-MBLSTM technique involves three subpro-cesses such as pre-processing,prediction,and hyperparameter *** OMHA-MBLSTM technique employs min-max normalization as a pre-proces-sing ***,the MBLSTM model is applied for the prediction of stability level of the smart grids in *** the same time,the moth swarm algorithm(MHA)is utilized for optimally modifying the hyperparameters involved in the MBLSTM *** ensure the enhanced outcomes of the OMHA-MBLSTM technique,a series of simulations were carried out and the results are inspected under several *** experimental results pointed out the better outcomes of the OMHA-MBLSTM technique over the recent models.

关键词： Stability prediction smart grid cyber physical energy systems deep learning data analytics moth swarm algorithm

Isolation, purification and structure elucidation of three newbioactive secondary metabolites from Streptomyces lividans AM

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BIOCELL 2021年第5期45卷 1263-1271页

作者： mohammad EL-METWALLY MAMDOUH ABDEL-MOGIB manal ELFEDAWY GAAD SOHSAH AHMED REZK MAHMOUD MOUSTAFA MOHAMED SHAABAN Botany and Microbiology Department Faculty of ScienceDamanhour UniversityDamanhour22511Egypt Chemistry Department Faculty of ScienceMansoura UniversityEl-Mansoura35516Egypt Bioprocess Development Department Genetic Engineering and Biotechnology Research InstituteCity of Scientific Research and Technological Applications(SRTA-City)New Borg El-Arab CityAlexandria21934Egypt Biology Department College of ScienceKing Khalid UniversityAbha9004Saudi Arabia Chemistry of Natural Compounds Department Division of Pharmaceutical IndustriesNational Research CentreDokki-Cairo12622Egypt Organic and Bioorganic Chemistry Department of ChemistryBielefeld UniversityBielefeld33615Germany

Microorganisms are a huge mine of bioactive metabolites,and actinomycetes are one of the very active groups in this *** this article,we are concerned about the full taxonomical characterization of Streptomyces lividans AM,isolated from Egyptian *** isolate produced three new bioactive metabolites,namely:1-Nona-decanoyl,4-oleyl disuccinate(1),filoboletic acid;(9Z,11E)-8,13-dihydroxy octadeca-9,11-dienoic acid(2),and sitosteryl-3β-D-glucoside(3).Extensive 1D and 2D NMR and HR-mass spectrometry were used to elucidate the structures of the three ***,ten known compounds were also *** antimicrobial activity of the producing organism and newly reported compounds(1–3)was investigated against a selected group of pathogenic microorganisms.A full taxonomical characterization of the strain was described as well.

关键词： Bioactive metabolites Streptomyces sp. Taxonomy Biological activity

Securing Arabic Contents Algorithm for Smart Detecting of Illegal Tampering Attacks

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Computers, Materials & Continua 2022年第2期70卷 2879-2894页

作者： Mesfer Al Duhayyim manal Abdullah Alohali Fahd N.Al-Wesabi Anwer Mustafa Hilal mohammad Medani Manar Ahmed Hamza Department of Natural and Applied Sciences College of Community-AflajPrince Sattam bin Abdulaziz UniversitySaudi Arabia Department of Information Systems College of Computer and Information SciencesPrincess Nourah bint Abdulrahman UniversitySaudi Arabia Department of Computer Science King Khalid UniversityMuhayel AseerSaudi Arabia Faculty of Computer and IT Sana’a UniversitySana’aYemen Department of Computer and Self Development Preparatory Year DeanshipPrince Sattam bin Abdulaziz UniversityAlKharjSaudi Arabia

Themost common digital media exchanged via the Internet is in text *** Arabic language is considered one of themost sensitive languages of content modification due to the presence of diacritics that can cause a change in the *** this paper,an intelligent scheme is proposed for improving the reliability and security of the text exchanged via the *** core mechanism of the proposed scheme depends on integrating the hidden Markov model and zero text watermarking *** watermark key will be generated by utilizing the extracted features of the text analysis process using the third order and word level of the Markov *** Embedding and detection processes of the proposed scheme will be performed logically without the effect of the original *** proposed scheme is implemented using PHP with VS code *** simulation results,using varying sizes of standard datasets,show that the proposed scheme can obtain high reliability and provide better accuracy of the common illegal tampering *** results with other baseline techniques show the added value of the proposed scheme.

关键词： Tampering detection zero-watermarking soft computing text analysis hidden Markov model

Multisystem inflammatory syndrome in pediatric COVID-19 patients:a meta-analysis

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World Journal of Pediatrics 2021年第2期17卷 141-151页

作者： Eman A.Toraih mohammad H.Hussein Rami M.Elshazli Adam Kline Ruhul Munshi Nasrin Sultana Sharven Taghavi Mary Killackey Juan Duchesne manal S.Fawzy Emad Kandil Department of Surgery Tulane UniversitySchool of MedicineNew OrleansLAUSA Genetics Unit Department of Histology and Cell BiologyFaculty of MedicineSuez Canal UniversityIsmailiaEgypt Department of Biochemistry and Molecular Genetics Faculty of Physical TherapyHorus University-EgyptNew Damietta 34517Egypt Tulane University School of MedicineNew OrleansLAUSA Division of Endocrine and Oncologic Surgery Department of SurgerySchool of MedicineTulane UniversityNew OrleansLA 70112USA Department of Medicine Larkin Community HospitalFlorida.MiamiUSA Trauma/Acute Care and Critical Care Department of SurgeryTulane UniversitySchool of MedicineNew OrleansLAUSA Department of Medical Biochemistry and Molecular Biology Faculty of MedicineSuez Canal UniversityIsmailiaEgypt Department of Biochemistry College of MedicineNorthern Border UniversityArarKingdom of Saudi Arabia

Background We aimed to systematically review the clinical and laboratory features of patients with the multisystem inflam-matory syndrome in pediatrics diagnosed during the COVID-19 *** sources A literature search in Web of Science,PubMed,Scopus,and Science Direct was made up to June 29,*** Analysis of 15 articles(318 COVID-19 patients)revealed that although many patients presented with the typical multisystem inflammatory syndrome in pediatrics,Kawasaki-like features as fever(82.4%),polymorphous maculopapular exanthema(63.7%),oral mucosal changes(58.1%),conjunctival injections(56.0%),edematous extremities(40.7%),and cervical lymphadenopathy(28.5%),atypical gastrointestinal(79.4%)and neurocognitive symptoms(31.8%)were also *** had elevated serum lactic acid dehydrogenase,D-dimer,C-reactive protein,procalcitonin,interleukin-6,troponin I levels,and *** 77.0%developed hypotension,and 68.1%went into shock,while 41.1%had acute kidney *** care was needed in 73.7%of cases;13.2%were intubated,and 37.9%required mechanical *** immunoglobulins and steroids were given in 87.7%and 56.9%of the patients,respectively,and anticoagulants were utilized in 67.0%.Pediatric patients were discharged after a hospital stay of 6.77 days on average(95%CI 4.93-8.6).Conclusions Recognizing the typical and atypical presentation of the multisystem inflammatory syndrome in pediatric COVID-19 patients has important implications in identifying children at *** cardiac and renal decompensation and early interventions in patients with multisystem inflammatory syndrome is critical to prevent further morbidity.

关键词： COVID-19 Kawasaki-like syndrome Multisystem inflammatory syndrome in pediatrics SARS-CoV-2

Complexing Properties of Acid Alizarin Violet with Copper, Cobalt and Nickel in Micellar Media Containing SDS, CTAB and TX-100

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American Journal of Analytical Chemistry 2014年第1期5卷 1-7页

作者： Fawwaz Jumean Magdy El-Dakiky Adnan Manassra manal Abdul Kareem mohammad Abu Alhaj Mustafa Khamis Department of Biology Chemistry and Environmental Sciences American University of Sharjah Sharjah United Arab Emirates Department of Biology Chemistry and Environmental Sciences American University of Sharjah Sharjah United Arab Emirates 2Department of Chemistry and Chemical Technology Faculty of Science & Technology Al-Quds University East Jerusalem Palesti Department of Chemistry and Chemical Technology Faculty of Science & Technology Al-Quds University East Jerusalem Palestine

The interaction of the dye acid alizarin violet (AVN) with three transition metals was followed spectrophotometrically in water and in micellar solutions of the cationic cetyltrimethylammonium bromide (CTAB), the anionic sodium dode- cyl sulfate (SDS) and the nonionic triton X-100 (TX-100). The stoichiometric ratios for the complexes of AVN with each metal ion were determined by the mole ratio and the continuous variation methods. In water, the metal to dye ratios in the complexes were 1:2, 1:3 and 1:1 for Cu2+, Co2+ and Ni2+, respectively. For Ni2+ the ratio changed to 1:3 in micellar CTAB. All other ratios were unchanged in the three micellar solutions. The formation constant (βn) of the complex in water was 1.00 × 1010 for Cu2+, 4.66 × 1014 for Co2+ and 9.03 × 104 for Ni2+. βn decreased in micellar TX-100: for Cu2+ to 6.88 × 108, for Co2+ to 1.56 × 1014 and for Ni2+ to 8.65 × 104. By contrast, micellar CTAB increased βn for Cu2+ and Ni2+. For Cu2+, the increase was to 5.19 × 1010, but for Ni2+ a large jump was observed, to 1.16 × 1015. For Co2+, βn dropped to 2.16 × 1014 in CTAB. Micellar SDS decreased βn for Cu2+ and Co2+ complexes to 5.38 × 109 and 1.76 × 1014, respectively, but increased that of the Ni2+ complex to 4.40 × 105. These observations were explained in terms of structural properties.

关键词： Complexation AVN Micellization

Safety and effi cacy of hepatitis A vaccine in children with chronic liver diseas

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World Journal of Gastroenterology 2006年第45期12卷 7337-7340页

作者： Hanaa Mostafa El-Karaksy manal Ismail El-Hawary Nehal mohammad El-Koofy Rokaya El-Sayed Mona Al-Saeed El-Raziky Samah Asaad Mansour Gamal mohammad Taha Fatma El-Mougy Department of Pediatrics Cairo University Egypt Department of Pediatrics Fayoum University Egypt Department of Pediatrics Beni-Swaif University Egypt Department of Chemical Pathology Cairo University Egypt

AIM： To study the safety and efficacy of hepatitis A vaccine （HAV） in children with chronic liver disease of various etiologies. METHODS： Eleven children with chronic liver disease and thirteen age- and sex-matched controls negative for HAV antibodies were vaccinated against hepatitis A after they gave their informed consent. Children with uncontrolled coagulopathy or signs of hepatic decompensation were excluded. The vaccine （Havrix： 720 ELISA units in 0.5 mL, from GlaxoSmithKline Biologicals） was given intramuscularly in the deltoid in 2 doses 6 mo apart. Children were tested for HAV antibodies one and six months after the ist dose and one month after the 2^nd dose. Total serum bilirubin, alanine aminotransferase （ALT）, and aspartate aminotransferase （AST） were determined immediately before and after one month of the 1st dose of the vaccine. RESULTS： Only 7 out of the 11 patients were positive for HAV antibodies after the 1^st dose of the vaccine, as compared to 100% of the controls. One month after the 2nd dose, all patients tested were positive for HAV antibodies. No deterioration in liver functions of patients was noted after vaccination. No adverse events, immediate or late, were reported by the mothers after each dose of the vaccine. CONCLUSION： Hepatitis A vaccine is both safe and effective in this small studied group of children with chronic liver disease. Given the high seroconversion rate, post-vaccination testing for HAV antibodies is not needed.

关键词： Children Chronic liver disease Hepatitis A Hepatitis A vaccine

Dubai Primary Health Care Centers Conformation to WHO Age-Friendly Primary Healthcare Recommendations

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Advances in Aging Research 2017年第6期6卷 83-92页

作者： Tamer Mohamed Farid Abdellatif Amal Mohamad Saleh Abdulrahim Al Jaziri manal mohammad Omran Taryam Nahed AbdulKhaleq Monsef Amel Ibrahim Buharoun Salah Ahmed Mohamed Elbadawi Moulham Saleh Ashtar Elderly Care Unit Health Affairs Department Primary Health Care Services Sector Dubai Health Authority Dubai United Arab Emirates Primary Health Care Services Sector Dubai Health Authority Dubai United Arab Emirates Health Affairs Department Primary Health Care Services Sector Dubai Health Authority Dubai United Arab Emirates Health Centres Department Primary Health Care Services Sector Dubai Health Authority Dubai United Arab Emirates

The WHO project for conforming PHC to requirements of all age groups has resulted in publishing a toolkit for age-friendly PHC in 2008. The toolkit included checklists for physical environment and signage properties. This study matched the current physical environment properties of DHA’s PHC Health Centers against WHO’s recommendations. This is a cross sectional descriptive study that included visits to all 12 Primary Health Care Centers in Dubai city during August-September 2016 with the objective to assess the degree of fulfillment of current properties of Health Centers building to the recommendations of WHO as listed in “Age-friendly Primary Health Care Centres Toolkit” [1]. The study found that 81.86% of physical environment properties are matching the recommendation of WHO, while signage matching was 44.6%. The study concluded that most PHC properties have a physical design that met WHO’s recommendations. The two major deviations were accessibility by public transportations and presence of grab bars. Factors that had a significant impact on design were compliance with multiple international and local standards, the availability of private cars, and the availability of wheel chairs. Signage in DHA’s health centers followed a central plan that differed from WHO’s recommendations.

关键词： World Health Organization (WHO) Primary Health Care (PHC) Elderly Care Unit Dubai Health Authority (DHA)