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Development of New Strategy for Non-Antibiotic Therapy: Dromedary Camel Lactoferrin Has a Potent Antimicrobial and Immunomodulator Effects

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Advances in Infectious Diseases 2013年第4期3卷 231-237页

作者： Alaa B. Ismael Salama M. Abd El Hafez manal B. Mahmoud Abdel-Kader A. Elaraby Hany M. hassan Department of Medical Biotechnology Faculty of Applied Medical Sciences Taif University Turaba KSA Department of Animal Medicine Faculty of Veterinary Medicine Zagazig University Zagazig Egypt Department of Medical Microbiology Faculty of Applied Medical Sciences Taif University Turaba KSA Immunobiology and Immunopharmacology Unit Animal Reproduction Research Institute (ARRI) Giza Egypt Holding Company for Biological Products & Vaccines VACSERA Giza Egypt Immunobiology and Immunopharmacology Unit Animal Reproduction Research Institute (ARRI) Giza Egypt

The human and bovine lactoferrin have been studied extensively, but very few reports have been published concerning camel lactoferrin (cLf). The present study aimed to isolate cLf and evaluate its efficiency including antimicrobial activity and immunomodulator effects. cLf isolation was attempted from camel milk whey using a cation exchange chromatography by SP-Sepharose. The antimicrobial activity of the isolated cLf was investigated against Staphylococcus aureus (S. aureus), Streptococcus agalactiae (S. agalactiae), Escherichia coli (E. coli) and Pseudomonas aeruginosa (P. aerogenosa) strains. The immune effect of cLf was studied by lymphocyte transformation test. It was found that cLf was separated around molecular weight of 80 kDa and showed significant inhibitory effect against E. coli followed by P. aeruginosa, S. agalactiae and S. aureus. cLf increased lymphocyte transformations mean values in a dose dependant manner. The highest transformations mean value was determined at 50 μg/mL. In conclusion, these results suggest that cLf is a potent natural antimicrobial and novel immunomodulator agent.

关键词： Dromedary Camel Lactoferrin Isolation Antimicrobial and Immunomodulator Effects

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Effect of Health Education Program on Self-Efficacy and Functional Capacity of Patients with Coronary Artery Bypass Surgery in Khartoum State-Sudan, 2015-2019

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World Journal of Cardiovascular Surgery 2023年第12期13卷 167-180页

作者： Mohamed Idriss Yahya Musa Egbal Abbashar Algamar manal Elzein Musa Ismail Osama Mohamed Elsanousi Amair Siddig Alhussein Zeinab Abaker Ahmed Omer Abdalgabar Musa hassan Assistant Professor in Medical-Surgical Nursing Department of Nursing Faculty of Applied Medical Sciences Buraydah College Buraydah KSA Associate professor in Pediatrics Nursing & Child Health Faculty of Applied Medical Sciences Buraydah College Buraydah KSA Assistant Professor in Obstetric & Gynecological Nursing Faculty of Applied Medical Sciences Buraydah College Buraydah KSA Associate Professor and HoD Department of Surgery Faculty of Medicine National Ribat University Khartoum Sudan Assistant Professor of Surgery Faculty of Medicine National Ribat University and a Cardiac Surgeon at Ahmed Qassim Hospital Khartoum Sudan Assistant Professor in Obstetric & Gynecological Nursing Faculty of Nursing Sciences Alneelain University Khartoum Sudan PhD Candidate Medical Surgical Nursing Hamad Medical Corporation Faculty of Nursing Science Qatar-Omdurman Islamic University Khartoum Sudan

Coronary heart disease is among the most prevalent and costly of all global health problems. Coronary artery bypass grafting (CABG) has been increasingly used since the 1960s. Coronary heart disease is a leading cause of death worldwide, including Sudan. Self-efficacy and functional capacity is a critical factor for quality of life in patients who has undergone CABG as well as for their caregivers from their families. Aim of the Study: To explore the effects of an educational program on self-efficacy and functional capacity of patients after CABG. 1) There will be no significant difference between the intervention group and control group concerning knowledge regarding Self-efficacy and functional capacity post CABG surgery. 2) The application of our educational program for the patients will enhance the patients with CABG surgery and improve knowledge about Self-efficacy and functional capacity post CABG surgery. 3) There are some socio demographic factors that affect the response to the educational program. Methods: This was a quasi-experimental, interventional and hospital-based study, including pre-test, a post-test and follow-up test, with a control group, conducted during the period from September 2014 to June 2019. Patients were recruited consecutively to the cases and control group using convenience sampling. The sample consisted of 76 patients;41 as cases and 35 as control group. The sample included those who had undergone CABG in Khartoum State. Relevant data were collected using a checklist to monitor the effect of a health education program on self-efficacy and functional capacity of the patients. Result: The results showed marked improvement in patients’ self-efficacy and functional capacity between pretest and posttest for the study group;p-value = (0.001) in the health status of cases in comparison to the control group. The indices were observed to be higher for patients who received a nursing educational program throughout the study period;p-value = (0

关键词： Education Program Self-Efficacy Functional Capacity Coronary Artery Bypass Surgery

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Kernel Thesis Reproduction and Truncated Toeplitz Operators

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Journal of Applied Mathematics and Physics 2023年第12期11卷 4016-4026页

作者： Zakieldeen Aboabuda Mohamed Alhassn Ali Amna Mahmoud Ahmed Bakhit Isra Abdalhleem hassan Ali manal Yagoub Ahmed Juma Tahani Mahmoud Ahmed Mohamed Sumia Izzeldeen Abdallah Abdelmajeed Deanship of the Preparatory Year Prince Sattam Bin Abdulaziz University Alkharj Saudi Arabia Department of Mathematic Faculty of Science University of Qassim Buraidah Saudi Arabia Department of Mathematic Gezira Collage of Technology Khartoum Sudan

Important operator characteristics (such boundedness or compactness) for particular classes of operators on particular reproducing kernel Hilbert spaces may be impacted by the behaviour of the operators on the reproducing kernels. These results have been shown for Toeplitz operators on the Paley-Wiener space, a reproducing kernel Hilbert space over C. Furthermore, we show how the norm of such an operator has no relation to the supremum of the norms of the pictures of the normalization reproducing kernels of the space. As a result, if this supremum is finite, the operator is implicitly bounded. To further demonstrate that the operator norm is not the same as the supremum of the norms of the pictures of the real normalized reproducing kernels, another example is also provided. We also set out a necessary and sufficient condition for the operators’ compactness in terms of their limiting function on the reproducing kernels.

关键词： Toeplitz Operators Compact Operator The Reproducing Kernel

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Acute Lymphoblastic Leukemia in Childhood Following Pyoderma Gangrenosum

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Journal of Cancer Therapy 2020年第11期11卷 715-721页

作者： Aziza El Ouali manal Azizi Nadia Bouhafs Mounia Rimani Ayad Ghannam Abdeladim Babakhouya Maria Rkain Noufissa Benajiba Hematology and Oncology Unit Departments of Pediatric UHC Mohammed VI Medical School of OUJDA University Mohamed I Oujda Morocco hassan Pathological Anatomy Center Rabat Morocco

Pyoderma gangrenosum (PG) is a rare but serious ulcerating skin disease that occurs either idiopathically or associated with various systemic diseases and malignant tumors. Although the association of PG with myeloid malignant tumors is well known, their association with lymphoid malignant tumors, especially in children is extremely rare. We present here a case of PG in a 4-year and 4 months female child, diagnosed in the Pediatrics department, which had initially evolved well with oral corticosteroid therapy and a local dermocorticoid. The development was marked 7 months after stopping corticosteroid treatment by the occurrence of acute lymphoblastic leukemia. This case of PG is presented in the intention of increasing awareness of this uncommon condition with may oc

关键词： Pyoderma Gangrenosum Childhood Leukemia

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Educational Program for Pregnant Women Regarding Obstetrics Dangerous Signs in Rural Areas

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Open Journal of Obstetrics and Gynecology 2021年第5期11卷 529-552页

作者： Mai Ahmed Gobran Marwa Tharwat Abdel Fatah Mohamed S. H. Ramadan Ghada A. Amer M. Mahmoud Rabeh Rofida M. Elshafei Almandouh Hussein Bosilah Hala hassan Saied Khalil Sharbat Thabet hassanine manal Mansour Mostafa Mohamed Sobhy Bakry Safaa A. Ibrahim Eman Ramadan Abd El Fattah Abeer M. Abdelbary Pathology Faculty of Medicine Zagazig University Zagazig Egypt Anatomy Faculty of Medicine Zagazig University Zagazig Egypt Obstetrics & Gynecology Faculty of Medicine Zagazig University Zagazig Egypt Zoology (Physiology) Department Faculty of Science Zagazig University Zagazig Egypt Stem Sharqiai Zagazig Egypt Nursing Faculty of Medicine Fayoum University Fayoum Egypt Obstetrics & Gynecology Faculty of Medicine Fayoum University Fayoum Egypt

Background: Complications linked to postpartum & pregnancy are one of the major causes of female death. In order to understand the causes of complications and encourage women to take sufficient action in order to receive emergency treatment, a critical step should therefore be taken to minimize complications related to pregnancy, in order to ensure the safety of both women and newborns. Aim of the work: Evaluate the effectiveness of the education programs for pregnant women on obstetric danger signs in rural areas and help minimize the incidence of pregnancy loss and comorbidities. Methods: A quasi-experimental design on 70 women from a population of through 372 women in six-month in antenatal clinics recruited from the previously mentioned settings with pre- and post-test was conducted at antenatal clinics (M.C.H centers) affiliated to the available geographical health zones in EL-fayoum rural area including: Al-sheikh hassan at sanorse. We collected the data of women characteristics by a self-administered interview q

关键词： Obstetric Danger Signs Knowledge Practice Obstetric Complications

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