检索结果-南通市图书馆

Association between Dopamine Transporter Gene (<i>DAT1</i>) Polymorphisms and Eating Disorders with Binge Eating Behavior

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Open Journal of Psychiatry 2017年第4期7卷 329-343页

作者： Takashi Hirata Takuji Uemura manabu shinohara Masami Hirano Department of Neuropsychiatry and Clinical Ethics Interdisciplinary Graduate School of Medicine University of Yamanashi Yamanashi Japan Health Care Center University of Yamanashi Yamanashi Japan Kyosai Hospital Yamanashi Japan

Objectives: Dyshomeostasis of the dopaminergic system is implicated in the pathophysiology of eating disorders (EDs). We have previously reported an association between 3'-UTR VNTR (three prime untranslated region variable number of tandem repeat) of the Dopamine Transporter 1 (DAT1) gene and ED with binge eating behavior (EDBEB). Here we investigated whether variants in the coding region of the DAT1 gene also associate with EDBEB. Methods: The coding region and exon-intron junctions of the DAT1 gene were screened by direct sequencing using genomic DNA from EDBEB patients (n = 90) and healthy subjects (n = 114) on whom 3'-UTR VNTR variants had been previously determined. Results: rs2270912 and rs28363130, two of five known polymorphisms found by this screen, were significantly associated with EDBEB patients by genotype (p = 0.003, p = 0.011, respectively) and allele (p = 0.003, p = 0.012, respectively) frequency compared with healthy subjects. Interestingly, these polymorphisms associate with the risk 3'-UTR VNTR variant of EDBEB. Conclusion: Although our sample size was small, we show here that rs2270912 and rs28363130 associates with EDBEB and might act with 3'-UTR VNTR as a haplotype. These findings support the notion that the DAT1 gene plays a key role in the dopaminergic system of EDBEB.

关键词： Eating Disorder Binge Eating Behavior DAT1 Association Study Polymorphism

Vascular anomaly in the levator aponeurosis of neurofibromatosis type 1

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Ophthalmology(English edition) 2017年第4期10卷 656-657页

作者： Satoru Kase Toshiya shinohara Mika Noda Susumu Ishida manabu Kase Department of Ophthalmology Teine Keijinkai HospitalSapporo 006-0811 Japan Department of Ophthalmology Faculty of Medicine and Graduate School of Medicine Hokkaido University Sapporo 060-8638 Japan Department of Surgical Pathology Teine Keijinkai HospitalSapporo 006-0811 Japan

Dear Editor,I am Satoru Kase,from the Department of Ophthalmology,Faculty of Medicine and Graduate School of Medicine,Hokkaido University,Sapporo City,Japan.I write to present a case of neurofibromatosis type 1（NF1）... 详细信息

关键词： Vascular anomaly in the levator aponeurosis of neurofibromatosis type 1 NF Figure type

Exact Solutions of the Cubic Duffing Equation by Leaf Functions under Free Vibration

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Computer Modeling in Engineering & Sciences 2018年第5期115卷 149-215页

作者： Kazunori shinohara Daido University 10-3 Takiharu-choMinami-kuNagoya 457-8530Japan

Exact solutions of the cubic Duffing equation with the initial conditions are *** exact solutions are expressed in terms of leaf functions and trigonometric *** leaf function r=sleafn(t)or r=cleafn(t)satisfies the ordinary differential equation dx2/dt2=-*** second-order differential of the leaf function is equal to-n times the function raised to the(2n-1)power of the leaf *** using the leaf functions,the exact solutions of the cubic Duffing equation can be derived under several *** solutions are constructed using the integral functions of leaf functions sleaf2(t)and cleaf2(t)for the phase of a trigonometric *** the leaf function and the trigonometric function are used in combination,a highly accurate solution of the Duffing equation can be easily obtained based on the data of leaf *** this study,seven types of the exact solutions are derived from leaf functions;the derivation of the seven exact solutions is detailed in the ***,waves obtained by the exact solutions are graphically visualized with the numerical results.

关键词： Duffing equation nonlinear equations ordinary differential equation leaf functions

Damped and Divergence Exact Solutions for the Duffing Equation Using Leaf Functions and Hyperbolic Leaf Functions

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Computer Modeling in Engineering & Sciences 2019年第3期118卷 599-647页

作者： Kazunori shinohara Daido University 10-3 Takiharu-choMinami-kuNagoya 457-8530Japan

According to the wave power rule,the second derivative of a functionχ(t)with respect to the variable t is equal to negative n times the functionχ(t)raised to the power of 2n?*** the ordinary differential equations numerically results in waves appearing in the *** ordinary differential equation is very simple;however,waves,including the regular amplitude and period,are drawn in the *** this study,the function for obtaining the wave is called the leaf *** on the leaf function,the exact solutions for the undamped and unforced Duffing equations are *** the ordinary differential equation,in the positive region of the variableχ(t),the second derivative d^2χ(t)/dt^2 becomes ***,in the case that the curves vary with the time under the conditionχ(t)>0,the gradient dχ(t)/d constantly decreases as time *** is,the tangential vector on the curve of the graph(with the abscissa and the ordinate χ(t)changes from the upper right direction to the lower right direction as time *** the other hand,in the negative region of the variableχ(t),the second derivative d^2χ(t)/dt^2 becomes *** gradient d χ(t)/d constantly increases as time *** is,the tangent vector on the curve changes from the lower right direction to the upper right direction as time *** the behavior occurring in the positive region of the variable χ(t)and the behavior occurring in the negative region of the variableχ(t)alternately occur in regular intervals,waves appear by these *** this paper,I present seven types of damped and divergence exact solutions by combining trigonometric functions,hyperbolic functions,hyperbolic leaf functions,leaf functions,and exponential *** each type,I show the derivation method and numerical examples,as well as describe the features of the waveform.

关键词： Leaf functions hyperbolic leaf functions lemniscate functions jacobi elliptic functions ordinary differential equations duffing equation nonlinear equations

Addition Formulas of Leaf Functions and Hyperbolic Leaf Functions

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Computer Modeling in Engineering & Sciences 2020年第5期123卷 441-473页

作者： Kazunori shinohara Department of Mechanical Systems Engineering Daido UniversityNagoya457-8530Japan

Addition formulas exist in trigonometric ***-angle and half-angle formulas can be derived from these ***,the relation equation between the trigonometric function and the hyperbolic function can be derived using an imaginary *** inverse hyperbolic function arsinher(r)■ro 1/√1+t^(2)dt p1tt2 dt is similar to the inverse trigonometric function arcsiner(r)■ro 1/√1+t^(2)dt p1t2 dt,such as the second degree of a polynomial and the constant term 1,except for the sign−and+.Such an analogy holds not only when the degree of the polynomial is 2,but also for higher *** such,a function exists with respect to the leaf function through the imaginary number i,such that the hyperbolic function exists with respect to the trigonometric function through this imaginary *** this study,we refer to this function as the hyperbolic leaf *** making such a definition,the relation equation between the leaf function and the hyperbolic leaf function makes it possible to easily derive various formulas,such as addition formulas of hyperbolic leaf functions based on the addition formulas of leaf *** the addition formulas,we can also derive the double-angle and half-angle *** then verify the consistency of these formulas by constructing graphs and numerical data.

关键词： Leaf functions hyperbolic leaf functions lemniscate functions Jacobi elliptic functions ordinary differential equations nonlinear equations

Lemniscate of Leaf Function

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Computer Modeling in Engineering & Sciences 2021年第1期126卷 275-292页

作者： Kazunori shinohara Department of Mechanical Systems Engineering Daido University10-3 Takiharu-choMinami-kuNagoya457-8530Japan

A lemniscate is a curve defined by two foci,F_(1) and F_(2).If the distance between the focal points of F_(1)−F_(2) is 2a(a:constant),then any point P on the lemniscate curve satisfy the equation PF_(1)·PF_(2)=a^(2).Jacob Bernoulli first described the lemniscate in *** Fagnano discovered the double angle formula of the lemniscate(1718).The Euler extended the Fagnano’s formula to a more general addition theorem(1751).The lemniscate function was subsequently proposed by Gauss around the year *** insights were summarized by Jacobi as the theory of elliptic functions.A leaf function is an extended lemniscate *** formulas of leaf functions have been presented in previous papers;these included the addition theorem of this function and its application to nonlinear *** this paper,the geometrical properties of leaf functions at n=2 and the geometric relation between the angle θ and lemniscate arc length l are presented using the lemniscate *** relationship between the leaf functions sleaf_(2)(l)and cleaf_(2)(l)is derived using the geometrical properties of the lemniscate,similarity of triangles,and the Pythagorean *** the literature,the relation equation for sleaf_(2)(l)and cleaf_(2)(l)(or the lemniscate functions,sl(l)and cl(l))has been derived analytically;however,it is not derived geometrically.

关键词： Geometry lemniscate of Bernoulli leaf functions lemniscate functions Pythagorean theorem triangle similarity

Varicella-zoster virus-associated meningitis,encephalitis,and myelitis with sporadic skin blisters:A case report

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2022年第2期10卷 717-724页

作者： Ken Takami Tsuneaki Kenzaka Ayako Kumabe Megumi Fukuzawa Yoko Eto Shun Nakata Katsuhiro shinohara Kazunori Endo Department of Internal Medicine Sainokuni Higashiomiya Medical CenterSaitama 331-8577SaitamaJapan Division of Community Medicine and Career Development Kobe University Graduate School of MedicineKobe 652-0032HyogoJapan Department of Neurology Sainokuni Higashiomiya Medical CenterSaitama 331-8577SaitamaJapan Department of Dermatology Sainokuni Higashiomiya Medical CenterSaitama 331-8577SaitamaJapan Emergency Department Sainokuni Higashiomiya Medical CenterSaitama 331-8577SaitamaJapan

BACKGROUND Varicella-zoster virus(VZV)generally causes chickenpox at first infection in childhood and then establishes latent infection in the dorsal root ganglia of the spinal cord or other *** reactivation owing to an impaired immune system causes inflammation along spinal nerves from the affected spinal segment,leading to skin manifestations(herpes zoster).Viremia and subsequent hematogenous transmission and nerve axonal transport of the virus may lead to meningitis,encephalitis,and *** such case is described in this *** SUMMARY A 64-year-old man presented with dysuria,pyrexia,and progressive disturbance in *** had signs of meningeal irritation,and cerebrospinal fluid(CSF)analysis revealed marked pleocytosis with mononuclear predominance and a CSF/serum glucose ratio of *** magnetic resonance imaging revealed hyperintense areas in the frontal *** had four isolated blisters with papules and halos on his right chest,right lumbar region,and left scapular *** giant cells were detected using the Tzanck *** epidermal cells with intranuclear inclusion bodies and ballooning degeneration were present on skin *** VZV antibody titers suggested previous infection,and the CSF tested positive for *** developed paraplegia,decreased temperature perception in the legs,urinary retention,and fecal *** patient was diagnosed with meningitis,encephalitis,and myelitis and was treated with acyclovir for 23 days and prednisolone for 14 *** gradual improvement,the urinary retention and gait disturbances persisted as *** VZV reactivation should be considered in differential diagnoses of patients with sporadic blisters and unexplained central nervous system symptoms.

关键词： Varicella-zoster virus Encephalitis Meningitis Myelitis Central nervous system Case report

Universal single-mode lasing in fully chaotic two-dimensional microcavity lasers under continuous-wave operation with large pumping power [Invited]

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Photonics Research 2017年第5期5卷 41-48页

作者： TAKAHISA HARAYAMA SATOSHI SUNADA SUSUMU shinohara Department of Applied Physics School of Advanced Science and Engineering Waseda University Faculty of Mechanical Engineering Institute of Science and Engineering Kanazawa University

For a fully chaotic two-dimensional(2D) microcavity laser, we present a theory that guarantees both the existence of a stable single-mode lasing state and the nonexistence of a stable multimode lasing state, under the assumptions that the cavity size is much larger than the wavelength and the external pumping power is sufficiently large. It is theoretically shown that these universal spectral characteristics arise from the synergistic effect of two different kinds of nonlinearities: deformation of the cavity shape and mode interaction due to a lasing medium. Our theory is based on the linear stability analysis of stationary states for the Maxwell–Bloch equations and accounts for single-mode lasing phenomena observed in real and numerical experiments of fully chaotic 2D microcavitylasers.

关键词： Universal single-mode lasing in fully chaotic two-dimensional microcavity lasers under continuous-wave operation with large pumping power

Extraction of yarn positional information from three-dimensional CT image of textile fabric using a yarn model for its structure analysis

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

仪器仪表学报 2008年第8期29卷 1569-1576页

作者： Toshihiro shinohara Jun-ya Takayama Shinji Ohyama Akira Kobayashi School of Biology-Oriented Science and Technology Kinki University Kinokawa-shi Wakayama-kenJapan Graduate School of Science and Engineering Tokyo Institute of Technology1-12-1 Meguro-kuTokyoJapan Faculty of University Evaluation and Research National Institution for Academic Degrees and UniversityEvaluation Kodaira-shi TokyoJapan

This paper proposes a novel method for analyzing a textile fabric structure to extract positional information regarding each yarn using three-dimensional X-ray computed tomography(3D CT) *** relationship among the yarns can be reconstructed using the extracted yarn positional *** this paper,a sequence of points on the center line of each yarn of the sample is defined as the yarn positional information,since the sequence can be regarded as the representative position of the *** sequence is extracted by tracing the *** yarn is traced by estimating the yarn center and direction and correlating the yarn part of the 3D CT image with a 3D yarn model,which is moved along the estimated yarn *** trajectory of the center of the yarn model corresponds to the positional information of the *** application of the proposed method is shown by experimentally applying the proposed method to a 3D CT image of a double-layered woven ***,the experimental results for a plain knitted fabric show that this method can be applied to even knitted fabrics.

关键词：纺织品 CT影像分析方法物理结构