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Brain region-specific roles of brain-derived neurotrophic factor in social stress-induced depressive-like behavior

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Neural Regeneration Research 2025年第1期20卷 159-173页

作者： man Han Deyang Zeng Wei Tan Xingxing Chen Shuyuan Bai Qiong Wu Yushan Chen zhen Wei Yufei Mei Yan Zeng Brain Science and Advanced Technology Institute Wuhan University of Science and TechnologyWuhanHubei ProvinceChina Geriatric Hospital Affiliated to Wuhan University of Science and Technology WuhanHubei ProvinceChina School of Public Health Wuhan University of Science and TechnologyWuhanHubei ProvinceChina

Brain-derived neurotrophic factor is a key factor in stress adaptation and avoidance of a social stress behavioral *** studies have shown that brain-derived neurotrophic factor expression in stressed mice is brain region–specific,particularly involving the corticolimbic system,including the ventral tegmental area,nucleus accumbens,prefrontal cortex,amygdala,and *** how brain-derived neurotrophic factor participates in stress processing in different brain regions will deepen our understanding of social stress *** this review,we discuss the expression and regulation of brain-derived neurotrophic factor in stress-sensitive brain regions closely related to the pathophysiology of *** focused on associated molecular pathways and neural circuits,with special attention to the brain-derived neurotrophic factor–tropomyosin receptor kinase B signaling pathway and the ventral tegmental area–nucleus accumbens dopamine *** determined that stress-induced alterations in brain-derived neurotrophic factor levels are likely related to the nature,severity,and duration of stress,especially in the above-mentioned brain regions of the corticolimbic ***,BDNF might be a biological indicator regulating stress-related processes in various brain regions.

关键词： amygdala chronic mild stress chronic social defeat stress corticolimbic system depression hippocampus medial prefrontal cortex nucleus accumbens social stress models ventral tegmental area

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论非战争军事行动中的安全工作

海军工程大学学报(综合版) 2011年第3期8卷 19-22页

作者：满振刚周琳解放军理工大学理学院

随着国家安全观的内涵不断延伸和非传统安全威胁不断上升,我军遂行非战争军事行动任务日益频繁,面临的情况日趋复杂,影响和危害部队安全稳定的因素逐渐增多。因此,我军应高度重视非战争军事行动中的安全工作,并从加强政治工作、注重预... 详细信息

随着国家安全观的内涵不断延伸和非传统安全威胁不断上升,我军遂行非战争军事行动任务日益频繁,面临的情况日趋复杂,影响和危害部队安全稳定的因素逐渐增多。因此,我军应高度重视非战争军事行动中的安全工作,并从加强政治工作、注重预测分析、完善应急管理机制、提升官兵针对性训练水平、进行装备革新等方面着手,把安全工作做细做实,保证在顺利完成任务的同时保持部队安全稳定。

关键词：非战争军事行动安全措施

Variation of cavity gas pressure in slopes with weak intercalation under seismic load

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Journal of Mountain Science 2016年第2期13卷 352-360页

作者： WANG Xiao-qun CHEN zhen-lin ZHOU Zhou SHEN man State Key Laboratory of Geohazard Prevention and Geoenvironment Protection Chengdu University of Technology

This study discussed how cavity gas pressure affects the stability of rock mass with fractures under well controlled laboratory ***-created void space created and the induced gas pressures have been the focus of active researches because they are associated with fast movement of large-scale landslides.A shaking table experiment was set up to mimic weak-intercalated rock slope under seismic *** cavity gas pressure would be produced in weak spots upon a sudden vibration *** drastically elevated gas pressure is believed to be responsible for the creation of cavities surrounding the tension *** dissipation of the excessive cavity gas pressure,the fractures are in unbounded *** observation explains that the slope body would be split and loosened under several aftershocks,and with the expanding of the cracks,the slope failure eventually *** research of the mechanism of cavity gas pressure could provide a novel insight into the formation mechanism of landslides under seismic load and has implications for the disaster prevention and control theory for the slope stability evaluation.

关键词： Landslide Fracture Deformation Weak intercalation Cavity gas pressure

Recent Advances in Purely Organic Room Temperature Phosphorescence Polymer

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Chinese Journal of Polymer Science 2019年第4期37卷 383-393,I0006页

作者： man-man Fang Jie Yang zhen Li Institute of Molecular Aggregation Science Tianjin University Department of Chemistry Wuhan University

Room temperature phosphorescence(RTP) has drawn increasing attention for its great potential in practical *** with large molecular weights and long chains tend to form coil, which can endow them with a high degree of possible rigidity and result in the much restricted non-radiative transition. Also, the intertwined structure of polymers could isolate the oxygen and humidity effectively, thus reducing the consumption of triplet excitons. In consideration of these points, organic polymers would be another kind of ideal platform to realize RTP effect. This short review summarized the design strategy of the purely organic room temperature phosphorescence polymers, mainly focusing on the building forms of polymers and the corresponding inherent mechanisms,and also gives some outlooks on the further exploration of this field at the end of this paper.

关键词： Room temperature phosphorescence Polymers Non-radiative transition

Individual-tree diameter growth model for Korean pine plantations based on optimized interpolation of meteorological variables

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Journal of Forestry Research 2021年第4期32卷 1535-1552页

作者： man Wang Yinghui Zhao zhen zhen Xingji Jin School of Forestry Northeast Forestry UniversityHarbin 150040HeilongjiangPeople’s Republic of China Key Laboratory of Sustainable Forest Ecosystem management-Ministry of Education Northeast Forestry UniversityHarbin 150040HeilongjiangPeople’s Republic of China

To explore the influence of meteorological variables on the growth of Korean pine(Pinus koraiensis *** Zucc.) plantations and provide a scientific reference for the production and management of Korean pine,three approaches to interpolate meteorological variables during the growing season(i.e.,May-September) were compared in Heilongjiang Province,*** meteorological variable interpolation results were then combined with stand and individual tree variables,based on data from 56 sample plots and 2886 sample trees from Korean pine plantations in two regions of the province to develop an individualtree diameter growth model(Model I) and an individualtree diameter growth model with meteorological variables(Model Ⅱ) using a stepwise regression ***,an individual-tree diameter growth model with regional effects(Model Ⅲ) was developed using dummy variables in the regression,and the significance of introducing these dummy variables was verified with an F-test statistical *** models were validated using an independent data set,and the predictive performance of the three models was assessed via the adjusted coefficient of determination(R_(a)^(2)) and root mean square error(RMSE).The results suggest that the growth increment in tree diameter of Korean pine plantations was significantly correlated with the natural logarithm of initial diameter(ln D),stand basal area(BAS),logarithmic deformation of the stand density index(ln SDI),ratio of basal area of trees larger than the subject tree to their initial diameter at breast height(DBH)(BAL/D),and the maximum growingseason precipitation(Pgmax).The individual-tree diameter growth models of Korean pine plantations developed in this study will provide a good basis for estimating and predicting growth increments of Korean pine forests over larger areas.

关键词： Mixed interpolation Korean pine plantations Individual-tree diameter growth model Regional effects

Complementarity between micro-micro and micro-macro entanglement in a Bose–Einstein condensate with two Rydberg impurities

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Communications in Theoretical Physics 2020年第2期72卷 30-37页

作者： zhen Li Yu Han Le-man Kuang Key Laboratory of Low-Dimensional Quantum Structures and Quantum Control of Ministry of Education Department of Physics and Synergetic Innovation Center for Quantum Effects and ApplicationsHunan Normal UniversityChangsha 410081China

We theoretically study complementarity between micro-micro and micro-macro entanglement in a Bose–Einstein condensate with two Rydberg *** investigate quantum dynamics of micro-micro and micro-macro entanglement in the micro-macro *** is found that strong micro-macro entanglement between Rydberg impurities and the BEC can be generated by the use of initial micro-micro entanglement between two Rydberg impurities,which acts as the seed entanglement to create micro-macro *** demonstrate a curious complementarity relation between micro-micro and micro-macro entanglement,and find that the complementarity property can be sustained to some extent even though in the presence of the BEC decoherence.

关键词： complementarity micro-macro entanglement micro-micro entanglement a Bose-Einstein condensate Rydberg impurities

Quantum dynamics of an impurity-doped Bose–Einstein condensate system

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Communications in Theoretical Physics 2020年第9期72卷 49-57页

作者： Yu Han zhen Li Le-man Kuang Key Laboratory of Low-Dimensional Quantum Structures and Quantum Control of Ministry of Education Department of Physics and Synergetic Innovation Center for Quantum Effects and ApplicationsHunan Normal UniversityChangsha 410081China

We study the quantum dynamics of an impurity-doped Bose–Einstein condensate(BEC) *** show how to generate the macroscopic quantum superposition states(MQSSs) of the BEC by the use of projective measurements on impurity atoms. It is found that the nonclassicality of MQSSs can be manipulated by changing the number of the impurities and their interaction with the BEC. It is shown that the BEC matter-wave field exhibits a collapse and revival phenomenon which reveals the quantum nature of the BEC matter-wave field. We investigate the micro-macro entanglement between the impurities and the BEC, and find enhancement of the micro-macro entanglement induced by the initial quantum coherence of the impurity atoms.

关键词： quantum dynamics an impurity-doped Bose–Einstein condensate macroscopic quantum superposition states quantum collapse and revival phenomenon micro-macro entanglement

An aero-engine life-cycle maintenance policy optimization algorithm: Reinforcement learning approach

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Chinese Journal of Aeronautics 2019年第9期32卷 2133-2150页

作者： zhen LI Shisheng ZHONG lin lin School of Mechatronics Engineering Harbin Institute of Technology

An aero-engine maintenance policy plays a crucial role in reasonably reducing maintenance cost. An aero-engine is a type of complex equipment with long service-life. In engineering,a hybrid maintenance strategy is adopted to improve the aero-engine operational reliability. Thus,the long service-life and the hybrid maintenance strategy should be considered synchronously in aero-engine maintenance policy optimization. This paper proposes an aero-engine life-cycle maintenance policy optimization algorithm that synchronously considers the long service-life and the hybrid maintenance strategy. The reinforcement learning approach was adopted to illustrate the optimization framework, in which maintenance policy optimization was formulated as a Markov decision process. In the reinforcement learning framework, the Gauss–Seidel value iteration algorithm was adopted to optimize the maintenance policy. Compared with traditional aero-engine maintenance policy optimization methods, the long service-life and the hybrid maintenance strategy could be addressed synchronously by the proposed algorithm. Two numerical experiments and algorithm analyses were performed to illustrate the optimization algorithm in detail.

关键词： Aero-engine Hybrid strategy Maintenance policy Optimization algorithm Reinforcement learning

Influence of coupled characteristics on the internally-staged combustor under low-power operation

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航空动力学报 2017年第1期32卷 42-52页

作者： KANG Yao lin Yu-zhen Hunan Aviation Powerplant Research Institute Aero Engine(Group)Corporation of China National Key Laboratory of Science and Technology on Aero-Engine Aero-thermodynamics School of Energy and Power EngineeringBeijing University of Aeronautics and Astronautics

An ultra-low emissions combustor,namely low emission stirred swirl(LESS)combustor was studied,based on a scheme of internally-staged/lean premixed and prevaporized(LPP)*** LESS combustor consists of central pilot stage and outer surrounded coaxially main stage,between which there exists aphysical isolation,namely the step *** existence of step height delayed the pilot and main jets *** and numerical studies were carried out to investigate the influence of the step height on the combustion performance.A single dome rectangular combustor was utilized to conduct the lean lightoff and blowout experiments,and pollutant emission *** experimental results showed that with the increase of step height by 38%,the lean lightoff and blowout fuel air ratio decreased by 57.4% and 37.5%,the NOx emission increased by 35.1%,and the combustion efficiency increased by 1.78%;while the CO,unburned hydrocarbons(UHC)emissions ***,the total pressure loss was kept nearly ***-reacting and reacting flow fields were numerically investigated to analyze the coupled characteristics of pilot and main jets with different step heights.A comparison of flow characteristics,spray structure,and combustion component as well as temperature field with different step heights was *** numerical results showed that the increase of the step height shifted the peak velocity *** enlargement of the primary recirculation zone(PRZ)resulted in the increase of the combustion efficiency and NOx emission,while the CO,UHC emissions decreeased.

关键词：航空动力编辑研究工作