检索结果-南通市图书馆

Integrinα6 Targeted Near Infrared Fluorescent Imaging and Photoacoustic Imaging of Hepatocellular Carcinoma in Mice

Journal of Clinical and Translational Hepatology 2023年第1期11卷 110-117页

作者： Yan-Zhu Lin You Wu De-Hai Cao Yong-Jian Peng Jun Deng Wen-Jie Lin Min-Yi Si-Tu Ling Zhuo Jie-Min Chen man-xia lei Rong-Bin Liu Wei-Guang Zhang Jian-Jun Li xiao-Chun Yang Guo-Kai Feng State Key Laboratory of Oncology in South China Collaborative Innovation Center for Cancer MedicineSun Yat-sen University Cancer CenterGuangzhouGuangdongChina Guangdong Institute for Drug Control Department of Biologic ProductsGuangzhouGuangdongChina Department of Endocrinology Nanfang HospitalSouthern Medical UniversityGuangzhouGuangdongChina Department of Ultrasound Sun Yat-sen Memorial HospitalSun Yat-sen UniversityGuangzhouGuangdongChina

Background and Aims:Hepatocellular carcinoma(HCC)is the fourth most common cause of cancer-related death and ranks sixth in terms of incident cases *** purpose of this study was to develop an effective and sensitive method to distinguish liver cancer tissues from normal tissues in HCC ***α6 is a promising cell surface target for molecular imaging of HCC,where it is overexpressed and is a prognostic *** previously identified an integrinα6-targeted peptide CRWYDENAC(RWY)that has been used for positron emission tomography(PET)imaging of HCC in mouse ***:We labeled the integrinα6-targeted RWY peptide with cyanine 7(Cy7)to form an optical probe(Cy7-RWY)for near infrared fluorescent(NIRF)and photoacoustic(PA)imaging in *** transplanted with subcutaneous HCC-LM3 or orthotopic HCC-H22 cells that overexpressed integrinα6 were intravenously injected with Cy7-RWY and its corresponding *** and PA images of mice were collected from 0 to 48 h after ***:Both NIRF and PA signals started to accumulate in the tumor 2 h after injection of Cy7-RWY and peaked at 24 ***:Cy7-RWY is a promising optical probe for NIRF and PA imaging of HCC in mice,and has potential clinical application for HCC detection.

关键词： Photoacoustic imaging Near-infrared fluorescent imaging Integrinα6 Peptide Molecular imaging Hepatocellular carcinoma

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

CaH2-promoted activity of Ni-carbonate interface for CO2 methanation

引用

Journal of Energy Chemistry 2025年第1期100卷 522-532页

作者： Jin-Peng Wang Guo-Cui Mao Hui-Lin Jiang Bao-xia Dong Yun-lei Teng School of Chemistry and Chemical Engineering Yangzhou University

Transition metal-carbonate interfaces often act as active sites in heterogeneous catalytic *** interface between transition metal and metal carbonate exhibits a dynamic equilibrium during the CO2hydrogenation reaction,involving surface carbonate hydrogenation and ***,there have been few reports on engineering the activity of the interface between transition metal and alkaline earth metal carbonate for catalytic *** work demonstrated that the incorporation of CaH2in Ni/CaCO3enhances the CO2methanation activity of the *** CO2conversion for Ni/CaH2-CaCO3reached 68.5%at 400°C,which was much higher than that of the Ni/CaCO3（31.6%） and Ni/CaH2-CaO （42.4%） ***,the Ni/CaH2-CaCO3catalysts remained stable during the stability test for 24 h at 400°C and 8 *** research revealed that CaH2played a crucial role in promoting the activity of the Ni-carbonate interface for ***2could modify the electronic structure of Ni and tune the structural properties of CaCO3to generate medium basic sites （OH groups）,which are favorable for the activation of H2and ***-situ Fourier transform infrared spectroscopy （FTIR） analysis combined with density functional theory calculations demonstrated that CO2activation occurs at the hydroxyl group （OH） on the CaH2-modified Ni-carbonate surface,leading to the formation of CO3H****,our study has confirmed that CO2methanation over the Ni/CaH2-CaCO3catalysts proceeds via the formate pathway.

关键词： Metal hydride Ni catalysts Carbonate Metal-carbonate interface

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Perilipin-2 mediates ferroptosis in oligodendrocyte progenitor cells and myelin injury after ischemic stroke

引用

Neural Regeneration Research 2025年第7期20卷 2015-2028页

作者： Jian Yang Jiang Wu Xueshun Xie Pengfei xia Jinxin Lu Jiale Liu lei Bai xiang Li Zhengquan Yu Haiying Li Department of Neurosurgery&Brain and Nerve Research Laboratory The First Affiliated Hospital of Soochow UniversitySuzhouJiangsu ProvinceChina Institute of Stroke Research Soochow UniversitySuzhouJiangsu ProvinceChina

Differentiation of oligodendrocyte progenitor cells into mature myelin-forming oligodendrocytes contributes to *** of remyelination due to oligodendrocyte progenitor cell death can result in severe nerve *** is an iron-dependent form of regulated cell death caused by membrane rupture induced by lipid peroxidation,and plays an important role in the pathological process of ischemic ***,there are few studies on oligodendrocyte progenitor cell *** analyzed transcriptome sequencing data from GEO databases and identified a role of ferroptosis in oligodendrocyte progenitor cell death and myelin injury after cerebral *** analysis suggested that perilipin-2(PLIN2)was involved in oligodendrocyte progenitor cell ***2 is a lipid storage protein and a marker of hypoxia-sensitive lipid droplet *** further investigation,we established a mouse model of cerebral ischemia/*** found significant myelin damage after cerebral ischemia,as well as oligodendrocyte progenitor cell death and increased lipid peroxidation levels around the infarct *** ferroptosis inhibitor,ferrostatin-1,rescued oligodendrocyte progenitor cell death and subsequent myelin *** also found increased PLIN2 levels in the peri-infarct area that co-localized with oligodendrocyte progenitor ***2 knockdown rescued demyelination and improved neurological *** findings suggest that targeting PLIN2 to regulate oligodendrocyte progenitor cell ferroptosis may be a potential therapeutic strategy for rescuing myelin damage after cerebral ischemia.

关键词： bioinformatics bulk RNA sequencing ferroptosis ischemic stroke myelin injury oligodendrocyte progenitor cell perilipin-2 single-cell RNA sequencing

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Low-temperature metal–oxide thin-film transistor technologies for implementing flexible electronic circuits and systems

引用

Journal of Semiconductors 2023年第9期44卷 3-10页

作者： Runxiao Shi Tengteng lei Zhihe xia man Wong State Key Laboratory of Advanced Displays and Optoelectronics and Technologies Department of Electronic and Computer EngineeringThe Hong Kong University of Science and TechnologyHong KongChina

Here we review two 300℃metal–oxide(MO)thin-film transistor(TFT)technologies for the implementation of flexible electronic circuits and ***-enhanced TFTs for suppressing the variation and shift of turn-on voltage(VON),and dual-gate TFTs for acquiring sensor signals and modulating VON have been deployed to improve the robustness and performance of the systems in which they are *** circuit building blocks based on fluorinated TFTs have been designed,fabricated,and characterized,which demonstrate the utility of the proposed low-temperature TFT technologies for implementing flexible electronic *** construction and characterization of an analog front-end system for the acquisition of bio-potential signals and an active-matrix sensor array for the acquisition of tactile images have been reported recently.

关键词： flexible electronics metal-oxide semiconductor thin-film transistor dual gate fluorination analog front-end system sensors

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Real-time performance analysis of non-saturated and non-slotted Ethernet based on a two-dimensional collision state model

引用

Frontiers of Computer Science 2015年第5期9卷 788-805页

作者： Ronggang BAI Jiqiang xia Qingfeng man School of Information Science and Technology Beijing Forestry University Beijing 100083 China School of Mechanical Engineering and Automation Beihang University Beijing 100191 China

This paper proposes a new method to analyze Ethernet performance. Currently, most studies on Ethernet performance assume that the channel is divided into time slots, or the network load is saturated with little attention to a non-slotted channel and the non-saturation status. However, this situation is more consistent with the practical application of Ethernet. This paper first calculates the original collision probability and the retransmission collision probability in the original load, then obtains the retransmission load of the network based on those two collision probabilities, and finally acquires the actual load of the network by an iterative method. In addition, the accuracy of the analysis is checked against simulation results.

关键词： BEB Ethernet networks MAC performance analysis collision probability two-dimensional collisionstate model

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Orientated-assembly of rod-like silica particles based on sandwich structure from the superhydrophobic template and the superhydrophilic substrates

引用

Chinese Chemical Letters 2016年第12期27卷 1797-1800页

作者： Lun Wan Chen-Hui Jiao man-Bo Zhang Jing-xia Wang lei Jiang Key Laboratory of Chemical Biology & Traditional Chinese Medicine Research (Ministry of Education) College of Chemistry and Chemical EngineeringHunan Normal University Technical Institute of Physics and Chemistry Chinese Academy of Sciences

The paper demonstrated a facile approach for the orientated assembly of the rod-like silica particles by sandwich structure from the combined effect of superhydrophobic template and the superhydrophilic substrates. The rod-like particles can be arranged in ring-like, square-like and etc from the confined effect of the template, which will produce an important insight for the oriented assembly ofanisotropic particles and the development of the novel functional materials and devices.

关键词： Anisotropic particles Rod-like silica Template-assisted Self-assembly Pattern

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Pre-processing filter design at transmitters for IBI mitigation in an OFDM system

引用

Journal of Systems Engineering and Electronics 2013年第5期24卷 722-728页

作者： xia Wang lei Wang School of Electronics and Information Engineering Xi'an Jiaotong University

In order to meet the demands for high transmission rates and high service quality in broadband wireless communication systems, orthogonal frequency division multiplexing （OFDM） has been adopted in some standards. However, the inter-block interference （IBI） and inter-carrier interference （ICI） in an OFDM system affect the performance. To mitigate IBI and ICI, some pre-processing approaches have been proposed based on full channel state information （CSI）, which improved the system performance. A pre-processing filter based on partial CSI at the transmitter is designed and investigated. The filter coefficient is given by the optimization processing, the symbol error rate （SER） is tested, and the computation complexity of the proposed scheme is analyzed. Computer simulation results show that the proposed pre-processing filter can effectively mitigate IBI and ICI and the performance can be improved. Compared with pre-processing approaches at the transmitter based on full CSI, the proposed scheme has high spectral efficiency, limited CSI feedback and low computation complexity.

关键词： pre-processing filter inter-block interference (IBI) mitigation limited feedback orthogonal frequency division multiplexing (OFDM).

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Dialectics of nature： Temporal and spatial regulation in material sciences

引用

Nano Research 2017年第4期10卷 1115-1124页

作者： Jianlong xia lei Jiang School of Chemistry Chemical Engineering and Life Science State Key Laboratory of Advanced Technology for Materials Synthesis and Processing Wuhan University of Technology No. 122 Luoshi Road Wuhan 430070 China Laboratory of Bioinspired Smart Interfacial Science Technical Institute of Physics and Chemistry Chinese Academy of Sciences Beijing 100190 China

The cooperative interaction distance measure has been proposed as a novel law pertaining to dialectics of nature, and has been extensively carried out in the design of functional nanomaterials. However, the temporal and spatial dimensions are akin to yin and yang, and thus temporal regulation needs to be accounted for when implementing the above-mentioned principle. Here, we summarize recent advances in temporally and spatially regulated materials and devices. We showcase the temporal regulation of organic semiconductors for organic photovoltaics （OPVs） using the example of exciton lifetime manipulation. As an example of spatial regulation, we consider the distribution of charge carriers in core-shell quantum dot （QD） nanocrystals for modulating their optical properties. Long exciton lifetime can in principle increase the exciton diffussion length, which is desiable for high-efficiency large-area OPV devices. Spatially regulated QDs are highly valuable emitters for light-emitting applications. We aim to show that cooperative spatio-temporal regulation of nanomaterils is of vital importance to the development of functional devices.

关键词： dialectics of nature temporal regulation spatial regulation singlet fission

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Quantum Stackelberg Duopoly Game in Depolarizing Channel

引用

Communications in Theoretical Physics 2008年第1期49卷 111-116页

作者： ZHU xia KUANG Le-man Department of Physics Hunan Normal University Changsha 410081 China

In this paper, we investigate the quantum Stackelberg duopoly （QSD） game in the noise environment with the depolarizing channel expressed by the Kraus-operator representation. It is found that the presence of the damping in the depolarizing channel always leads to the decrease of the quantities of the moves and payoffs of the two players in the QSD game. It is indicated that under certain conditions the first-mover advantage in the QSD game can be weakened due to the presence of the damping in the depolarizing channel.

关键词： quantum Stackelberg duopoly game Kraus operators depolarizing channel

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

INFLUENCE OF SURFACTANT ON TWO-PHASE FLOW REGIME AND PRESSURE DROP IN UPWARD INCLINED PIPES

引用

Journal of Hydrodynamics 2012年第1期24卷 39-49页

作者： xia Guo-dong CHAI lei Key Laboratory of Enhanced Heat Transfer and Energy Conservation Ministry of EducationCollege ofEnvironmental and Encrgy EngineeringBeijing University of TechnologyBeijing 100124China

The influence of a surfactant on the two-phase flow regime and the pressure drop in upward inclined pipes is investigated for various gas/liquid flow *** air/water and air/100 ppm sodium dodecyl sulphate aqueous solution are used as the working *** influence of the surfactant on the two-phase flow regime in upward inclined pipes is investigated using the electrical tomographic *** 0o,2.5o and 5o pipe inclinations,the surfactant has obvious effect on the transition from the stratified wavy flow to the annular flow,and the range of the stratified smooth flow regime is also extended to higher gas *** 10o pipe inclination,no stratified flow regime is observed in the air/water *** the air/surfactant solution system,however,the stratified flow regime can be found in the range of *** all inclination angles,the changes of the pressure gradient characteristics are accompanied with the flow pattern *** surfactant in a two-phase flow would reduce the pressure gradient significantly in the slug flow and annular flow *** the annular flow regime,the pressure gradient gradually becomes free of the influence of the upward inclined angle,and is only dependent on the property of the two-phase flow.

关键词： surfactant flow regime pressure drop two-phase flow

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：