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中国东部沿海四大城市群绿色效率的综合测度与比较

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中国人口·资源与环境 2019年第3期29卷 11-20页

作者：刘阳秦曼青岛大学商学院山东青岛266100 中国海洋大学管理学院山东青岛266100

东部沿海城市群作为国家经济增长的战略核心区,其均衡与绿色发展已成为中国理论界和政府迫切需要解决的重大问题。绿色效率是衡量区域绿色发展程度的关键指标,可以综合反映城市经济-社会-生态的协调发展水平。在梳理现有文献的基础上,... 详细信息

东部沿海城市群作为国家经济增长的战略核心区,其均衡与绿色发展已成为中国理论界和政府迫切需要解决的重大问题。绿色效率是衡量区域绿色发展程度的关键指标,可以综合反映城市经济-社会-生态的协调发展水平。在梳理现有文献的基础上,以京津冀城市群、山东半岛城市群、长三角城市群以及珠三角城市群为研究对象,基于2006—2015年的相关数据,采用三阶段DEA方法,综合测度四大沿海城市群绿色效率的时空特征。结果表明:①在剥离外部环境及随机因素的影响后,各地区的绿色效率发生较大变化,36个城市中除10个城市的绿色效率达到效率前沿面,其他城市仍有较大提升空间,且导致效率不足的因素是纯技术效率较低,而规模效率的影响不明显。②外部环境变量中,人均GDP、政府规划与城市绿色效率负相关;产业结构、城市化水平和市场开放程度与城市绿色效率正相关。③不同城市群的绿色效率等级存在异质性,四大城市群发展并不均衡,山东半岛城市群的绿色效率一直领先于其他三个城市群,城市群内部也表现出一定程度的失衡。④未来要继续加强发展第三产业,扩大劳动力就业水平,减少劳动力集聚造成的人员闲置;在加速城市化进程的同时,要注意发现城市化所造成的资源能源的过度消耗,把握城市化的速度,坚持以质量为导向,因地制宜制定地方政策,加强城市群之间以及城市群内部的合作与交流,实现要素资源的自由化流动,以推进沿海四大城市群的绿色均衡发展。

关键词：东部沿海城市群绿色效率三阶段DEA

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415颗未露髓冠折牙预后的回顾性研究

华西口腔医学杂志 2008年第5期26卷 516-518页

作者：管悦秦满北京大学口腔医院儿童口腔科

目的分析未露髓冠折牙的预后及影响预后的相关因素。方法对2000—2006年于北京大学口腔医院儿童口腔科注册的系统病历中,观察期大于等于6个月的未露髓恒牙冠折病历进行回顾性研究,记录患者的性别、年龄、外伤类型、是否伴有牙周组织损... 详细信息

目的分析未露髓冠折牙的预后及影响预后的相关因素。方法对2000—2006年于北京大学口腔医院儿童口腔科注册的系统病历中,观察期大于等于6个月的未露髓恒牙冠折病历进行回顾性研究,记录患者的性别、年龄、外伤类型、是否伴有牙周组织损伤、外伤牙位、牙根发育情况、外伤后就诊时间、是否接受急诊处理以及牙髓组织预后等内容。应用Logistic回归分析与简单冠折和冠折伴牙周组织损伤牙髓组织预后相关的因素。结果符合纳入标准的病历307份,涉及外伤牙415颗。冠折伴牙周组织损伤牙齿的牙髓坏死率为34.0%,简单冠折牙齿的牙髓坏死率为22.7%,二者间的差异具有统计学意义(P<0.05)。患者年龄和外伤类型与简单冠折牙髓组织预后具有显著相关性,牙根发育和外伤类型与冠折伴牙周组织损伤牙髓组织预后具有显著相关性。结论是否伴有牙周组织损伤与冠折牙齿的预后具有显著相关性。

关键词：冠折牙髓组织牙髓坏死

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重度龋儿童远缘链球菌基因多态性研究

中华口腔医学杂志 2009年第6期44卷 347-350页

作者：秦秀荣周琼秦满北京大学口腔医学院口腔医院儿童口腔科北京100081

目的采用随机引物聚合酶链反应（arbitrarily primed-polymerase chain reaction，AP-PCR）法初步探讨远缘链球菌在重度低龄儿童龋（severe early childhood caries，S-ECC）儿童与无龋儿童口腔中基因型分布的情况，分析其与婴幼儿龋发... 详细信息

目的采用随机引物聚合酶链反应（arbitrarily primed-polymerase chain reaction，AP-PCR）法初步探讨远缘链球菌在重度低龄儿童龋（severe early childhood caries，S-ECC）儿童与无龋儿童口腔中基因型分布的情况，分析其与婴幼儿龋发生之间的关系。方法选取北京市海淀区和西城区14所幼儿园178名42-54个月龄儿童，S-ECC（患龋牙数≥5）组87例，无龋组91人。嚼蜡法采集刺激性唾液进行分离培养，典型菌落行革兰染色、生化鉴定并保种，提取基因组DNA，PCR鉴定变形链球菌和远缘链球菌，AP-PCR法对远缘链球菌临床分离株行基因型分析。结果S-ECC组远缘链球菌检出率18％（16／87），显著高于无龋组的3％（3／91），差异有统计学意义（P〈0.01）。53株远缘链球菌临床分离株共检出22种基因型，S-ECC组个体基因型为1-3种，无龋组均为1种；此外，S-ECC组3名个体间存在相同基因型的菌株。S-ECC组基因型数与龋失补牙数间存在相关性（r=0.50，P〈0.05）。结论S-ECC儿童远缘链球菌检出率明显高于无龋儿童，且菌株间存在基因多态性，个体携带基因型的种类数与其致龋性间存在相关性；远缘链球菌无关个体间存在相同基因型的菌株。

关键词：聚合酶链反应基因型远缘链球菌

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基于衍射成像的荧光图像伪彩色自动融合研究

激光杂志 2020年第9期41卷 151-155页

作者：秦曼重庆工程学院重庆400056

为了提高荧光图像的高分辨融合能力,提出基于衍射成像的荧光图像伪彩色自动融合方法。构建荧光衍射图像的伪彩色特征分割模型,采用边缘区域信息融合方法进行荧光图像伪彩色特征检测与识别,采用联合结构相似性特征提取方法进行荧光图像... 详细信息

为了提高荧光图像的高分辨融合能力,提出基于衍射成像的荧光图像伪彩色自动融合方法。构建荧光衍射图像的伪彩色特征分割模型,采用边缘区域信息融合方法进行荧光图像伪彩色特征检测与识别,采用联合结构相似性特征提取方法进行荧光图像的边缘轮廓检测,建立荧光衍射图像的轮廓曲线演化分割模型,采用边缘模糊度特征提取方法进行荧光衍射图像的轮廓模型检测,根据图像的区域信息进行边缘梯度信息分割,构建荧光图像伪彩色径向纹理特征模型,采用衍射成像和荧光图像伪彩色表观模型重建的方法,实现荧光图像伪彩色自动融合。仿真结果表明,采用该方法进行荧光图像伪彩色融合的特征分辨能力较好,输出信噪比较高,提高了荧光图像伪彩色自动融合和检测能力。

关键词：衍射成像荧光图像伪彩色自动融合边缘轮廓检测

An empirical model for high energy density lithium-(ion)batteries with ultra-thick electrodes

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Tungsten 2024年第1期6卷 230-237页

作者： Li-Ming Jin Guang-Guang Xing Nan qin Yan-Yan Lu Jun-Sheng Zheng Cun-man Zhang Jim P.Zheng School of Automotive Studies and Clean Energy Automotive Engineering Center Tongji UniversityShanghai 201804China Department of Electrical Engineering University at BuffaloThe State University of New YorkBuffaloNY 14260USA

Increasing the electrode thickness is a significant method to decrease the weight and volume ratio of the inactive components for high energy density of the *** this contribution,we extracted a repeating unit in the configurations and establish the empirical energy density model based on some *** this model,the effects of the electrode thickness on the energy density for lithium-ion batteries(LIBs),lithium metal batteries(LMBs),and anode-free lithium batteries(ALBs)are evaluated quantitively with the current parameters of the *** results demonstrate that the structure evolutions from LIBs,LMBs to ALBs with the reduction of the anode weight contribution,the energy density can be well improved *** the increase of the thickness of the electrode provide another route to furthe r enhance the energydensity by decreasing the weight contribution of inactive materials;meanwhile the effects for ALBs are higher than LMBs and LIBs due to the higher weight ratio of inactive *** empirical energy density model is also applied into the practical system and provide intuitional results to guide the battery design for higher energy density.

关键词： Empirical model High energy density Lithium batteries Ultra-thick electrodes

Dexmedetomidine ameliorates diabetic intestinal injury by promoting the polarization of M2 macrophages through the MMP23B pathway

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World Journal of Diabetes 2024年第9期15卷 1962-1978页

作者： man Lu Xiao-Wen Guo Fang-Fang Zhang Dan-Hong Wu Di Xie Feng-qin Luo Department of Anesthesiology The First Affiliated Hospital of Zhejiang Chinese Medical University(Zhejiang Provincial Hospital of Traditional Chinese Medicine)Hangzhou 310006Zhejiang ProvinceChina Department of Emergency Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of MedicineShanghai 200092China

BACKGROUND Diabetes is often associated with gastrointestinal dysfunctions,which can lead to ***(DEX)is a commonly used sedative in perioperative diabetic patients and may affect gastrointestinal *** To investigate whether sedative doses of DEX alleviate diabetes-caused intestinal *** Sedation/anesthesia scores and vital signs of streptozotocin(STZ)-induced diabetic mice under DEX sedation were *** mice were divided into saline and DEX *** injecting sedatives intraperitoneally,tight junctions(TJs)and apoptotic levels were evaluated 24 hours later to assess the intestinal barrier *** role of DEX was validated using Villin-MMP23B flox/flox mice with intestinal epithelial *** vitro,high glucose and hyperosmolarity were used to culture Caco-2 monolayer cells with STZ *** techniques were used to monitor the barrier and mitochondrial *** MMP23B protein levels in the intestinal tissue of STZ-induced diabetic mice were significantly higher than those in the intestinal tissue of control mice,with the DEX group displaying decreased MMP23B ***-mediated TJ disruption,increased intestinal mucosal permeability,and systemic inflammation in wild-type mice might be reversed by *** Caco-2 cells,MMP23B was associated with increased reactive oxygen species accumulation,mitochondrial membrane potential depolarization,and TJ *** DEX reduces MMP23B,which may potentially contribute to STZ-induced intestinal barrier dysfunction,affecting TJ modification through mitochondrial dysfunction.

关键词： Diabetes Dexmedetomidine Intestinal barrier Piezo1 Tight junctions

Solid-state atomic hydrogen as a broad-spectrum RONS scavenger for accelerated diabetic wound healing

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National Science Review 2024年第2期11卷 196-206页

作者： man Luo qin Wang Gang Zhao Wei Jiang Cici Zeng qingao Zhang Ruyu Yang Wang Dong Yunxi Zhao Guozhen Zhang Jun Jiang Yucai Wang qing Zhu Key Laboratory of Precision and Intelligent Chemistry School of Chemistry and Materials Science University of Science and Technology of China Department of Radiology The First Affiliated Hospital of University of Science and Technology of China Division of Life Sciences and Medicine University of Science and Technology of China Shenzhen Senior High School Institute of Intelligent Innovation Henan Academy of Sciences

Hydrogen therapy shows great promise as a versatile treatment method for diseases associated with the overexpression of reactive oxygen and nitrogen species（RONS）. However, developing an advanced hydrogen therapy platform that integrates controllable hydrogen release, efficient RONS elimination, and biodegradability remains a giant technical challenge. In this study, we demonstrate for the first time that the tungsten bronze phase H0.53WO3（HWO） is an exceptionally ideal hydrogen carrier, with salient features including temperature-dependent highly-reductive atomic hydrogen release and broad-spectrum RONS scavenging capability distinct from that of molecular hydrogen. Moreover, its unique p H-responsive biodegradability ensures post-therapeutic clearance at pathological sites. Treatment with HWO of diabetic wounds in an animal model indicates that the solid-state atomic H promotes vascular formation by activating M2-type macrophage polarization and anti-inflammatory cytokine production, resulting in acceleration of chronic wound healing. Our findings significantly expand the basic categories of hydrogen therapeutic materials and pave the way for investigating more physical forms of hydrogen species as efficient RONS scavengers for clinical disease treatment.

关键词： atomic hydrogen RONS scavenger inflammatory regulation diabetic wound healing hydrogen therapy

基于课堂观察的美国体育教师效能评价工具及启示

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体育学刊 2021年第2期28卷 80-84页

作者：秦曼蒋健上海立信会计金融学院体育与健康学院上海201209 上海体育学院体育教育训练学院上海200438

美国开发的基于课堂观察的体育教师效能评价工具表现出两方面特性:一方面基于教育和评价理论,建立评价指标和评价流程,严格保证评价者资质,不断优化评价工具的信度和效度;另一方面通过实证研究识别体育教师有效课堂教学行为,为教师教学... 详细信息

美国开发的基于课堂观察的体育教师效能评价工具表现出两方面特性:一方面基于教育和评价理论,建立评价指标和评价流程,严格保证评价者资质,不断优化评价工具的信度和效度;另一方面通过实证研究识别体育教师有效课堂教学行为,为教师教学质量的诊断和改进提供重要参考。未来我国应从研发本土化评价工具、培养专业化评价人员、遵循规范性评价流程及建立互动型反馈机制4个方面优化体育教师效能评价的质量。

关键词：学校体育体育教师效能课堂观察评价工具美国

Constraints on the primordial curvature power spectrum by pulsar timing array data:a polynomial parameterization approach

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Communications in Theoretical Physics 2024年第1期76卷 96-104页

作者： qin Fei School of Mathematics and Physics Hubei Polytechnic UniversityHuangshi 435003China

The recent stochastic signal observed jointly by NANOGrav,parkes pulsar timing array,European pulsar timing array,and Chinese pulsar timing array can be accounted for by scalarinduced gravitational waves(SIGWs).The source of the SIGWs is from the primordial curvature perturbations,and the main contribution to the SIGWs is from the peak of the primordial curvature power *** effectively model this peak,we apply the Taylor expansion to parameterize *** the Taylor expansion parameterization,we apply Bayesian methods to constrain the primordial curvature power spectrum based on the NANOGrav 15 year data *** constraint on the primordial curvature power spectrum possesses a degree of generality,as the Taylor expansion can effectively approximate a wide range of function profiles.

关键词： pulsar timing array scalar-induced gravitational waves inflation