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Myocardial Perfusion Abnormalities in Patients with Hereditary Hypertrophic Cardiomyopathy: A Study of Three Cases and Review of the Literature

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World Journal of Cardiovascular Diseases 2023年第6期13卷 289-296页

作者： Ngardjibem Djita Ibrahima Sory Sylla mamadou Bassirou Bah Felix Collard Sana Samoura mamadou Aliou baldé Souleymane Diakité Ibrahima Sory Barry Alpha Koné Elhadj Yaya baldé Mariame Béavogui mamadou dadhi baldé Philippe Chevalier Department of Cardiology Alen&ccedilon Hospital Alen&ccedilon France Department of Cardiology CHU Ignace Deen Conakry Guinea Department of Cardiology Sino-Guinean Friendship Hospital Conakry Guinea Department of Cardiology CHU Lyon Lyon France

Introduction: Hypertrophic cardiomyopathy (HCM) belongs to the very heterogeneous group of cardiomyopathies. This study aimed to study myocardial perfusion abnormalities on scintigraphy and assess the risk of sudden death from ventricular arrhythmia in hereditary sarcomeric HCM. Patients and Methods: This is a retrospective and prospective descriptive study over 18 months (January 01, 2021, to July 31, 2022) on the records of patients over 18 with the diagnosis of hypertrophic sarcomeric cardiomyopathy with or without ventricular rhythm disorders and who have undergone myocardial scintigraphy. Results: Three patients were included. The average age of our patients was 66 years old. Dyspnea is the primary symptomatology found in our patients. One patient presented with syncope and unsustained ventricular tachycardia. His risk score for sudden death from ESC at five years is estimated at 6.45%, and the patient received an ICD in primary prevention. The average sudden death risk score of our patients was 3.78%. The mean LV wall thickness was 20 mm. The mean maximum left intraventricular gradient was 39 mmHg. Myocardial fibrosis was present in all our patients. Myocardial scintigraphy was normal in all cases. Conclusion: Hypertrophic cardiomyopathy is a very heterogeneous group of cardiomyopathies. The rhythmic risk is multifactorial and constitutes a significant prognostic factor.

关键词： Hypertrophic Cardiomyopathy Myocardial Scintigraphy Sudden Death Ven-tricular Arrhythmia

Dyspnea in a 26-Year-Old Woman with Fatal Left Atrial Myxoma

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World Journal of Cardiovascular Diseases 2023年第6期13卷 309-312页

作者： Ibrahima Sory Sylla mamadou Aliou baldé mamadou Bassirou Bah Sana Samoura Souleymane Diakité Alpha Koné Ibrahima Sory Barry Mariame Béavogui Djibril Sylla Elhadj Yaya baldé Mamadi Condé mamadou dadhi baldé Department of Cardiology Ignace Deen National Hospital Conakry Guinea Faculty of Health Sciences and Techniques Gamal Abdel Nasser University of Conakry Conakry Guinea Department of Cardiology Sino-Guinean Hospital Conakry Guinea Department of Internal Medicine CHU Conakry Guinea

Cardiac myxoma is one of the primary intracardiac tumours. We report the case of a left atrial myxoma in a 26-year-old female patient admitted for investigation of dyspnoea. Echocardiography led to the diagnosis of a giant hypermobile myxoma prolapsing into the left ventricle. The patient died before being evacuated for surgical treatment.

关键词： Myxoma Left Atrium Echocardiography

Asymptomatic Cardiac Manifestations in Rheumatoid Arthritis in Conakry (Guinea)

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Open Journal of Rheumatology and Autoimmune Diseases 2022年第2期12卷 57-64页

作者： Aly Badra Kamissoko Ibrahima Sory Barry Marina Sanda Cletus Dieuval Houngbegnon mamadou Lamine Diallo Abdoulaye Barry mamadou dadhi baldé Owonayo Oniankitan Department of Rheumatology Ignace Deen National Hospital Conakry Guinea Department of Cardiology Ignace Deen National Hospital Conakry Guinea Department of Rheumatology Sylvanus Olympio University Hospital Lome Togo

Introduction: Rheumatoid arthritis (RA) is the most common chronic inflammatory rheumatic disease. It is a systemic disease with extra-articular manifestations that can be life-threatening. In sub-Saharan Africa, there is little published information on cardiovascular manifestations in RA. Objective: The objective is to determine the asymptomatic cardiac manifestations during rheumatoid arthritis in Conakry. Patients and Methods: This was a cross-sectional study lasting 6 months from January 1, 2020 to June 30, 2020 in the rheumatology and cardiology departments of the Ignace Deen National Hospital. Patients with RA diagnosed according to the 2010 ACR/EULAR criteria, asymptomatic at the cardiovascular level, which had an ECG and echocardiography, were included in the study. Left ventricular diastolic dysfunction was considered in any patient with an E/A ratio 1, an E/E’ ratio > 10, and an LVEF = 50%, assessed by the Simpson biplane method and classified according to Redfield. Epidemiological, clinical and paraclinical data were analyzed using SPSS statistics 21.0 software. Results: Seventeen cases of rheumatoid arthritis (5.9%) were collected. There was a predominance of women with 14 cases (82.4%). The mean age of patients was 48.2 ± 11.9 years. The average duration of RA was 7.2 ± 4.2 years. Cardiovascular risk factors were dominated by overweight and obesity (58.8%) and sedentary lifestyle (35.3%). RA was predominantly high activity (DAS 28 ≥ 5.1) in 82.4% of patients. Anti-CCP antibodies were positive in 76.9% of cases. Fourteen patients (82.4%) had abnormal cardiac results. The electrocardiogram showed left atrial hypertrophy in 29.4% of cases, left ventricular hypertrophy (11.8%) and ventricular extrasystole (11.8%). The cardiac Doppler scan showed diastolic dysfunction of the left ventricle (47.1%) and moderate pericardial effusion in 11.8% of cases. Conclusion: The study found asymptomatic cardiac manifestations of rheumatoid arthritis. They were dominated b

关键词： Rheumatoid Arthritis Asymptomatic Manifestations Electrocardiography Sub-Saharan Africa Guinea

Knowledge of Patients and Their Accompanying Persons about Obliterative Arteriopathy of the Lower Limbs at Conakry University Hospital in 2022

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World Journal of Cardiovascular Diseases 2023年第9期13卷 511-519页

作者： Alpha Koné Alpha mamadou Diallo Sana Samoura Ibrahim Sory Barry Diane Kapché mamadou Bassirou Bah mamadou Saliou Diallo Souleymane Diakité Ibrahima Sory Sylla Elhadji Yaya baldé Zézé Onivogui Nicolas Zoumanigui Mariame Beavogui mamadou dadhi baldé Faculty of Health Sciences and Techniques Gamal Abdel Nasser University of Conakry Conakry Guinea Department of Cardiology Sino-Guinean Hospital Conakry Guinea Department of Diabetology and Endocrinology National Hospital Donka Conakry Guinea Department of Cardiology National Hospital Ignace Deen Conakry Guinea Department of Cardiology Mountain University of Bangangte Cameroon Bafousam Cameroon Department of Surgery Cardiovascular National Hospital Donka Conakry Guinea

Introduction: Obliterative arterial disease of the lower limbs is a marker of advanced atherosclerosis. It is one of the world’s most common cardiovascular diseases, present in one in five people over the age of 60, and carries an increased risk of morbidity and mortality. The aim of this study was to assess the knowledge of patients and their carers about obliterative arteriopathy of the lower limbs at Conakry University Hospital. Material and Methods: We conducted a descriptive cross-sectional study lasting 3 months, from March 12 to June 12, 2022 in the hospitals of the University Hospital of Conakry (Donka and Ignace Deen). Following free and informed consent, they were interviewed on the basis of a pre-established questionnaire. Socio-demographic data (age, gender, level of education) were collected, and knowledge of obliterative arterial disease of the lower limbs. Results: The study involved 159 people, comprising 106 patients (66.66%) and 53 accompanying persons (33.34%) in the hospitals of the University Hospital of Conakry (Donka and Ignace Deen). The 60 to 79 age group was the most represented (44.7%), with an average age of 55.4 ± 15.9 years and extremes of 20 to 84 years. Half (47.8%) had not attended school, and almost all (96.4%) of those who had attended school had a low level of education (primary and secondary). Almost all of them (91.2%) had never heard of AOMI. Only 5% identified at least one risk factor, diabetes, hypertension and smoking. Amputation was the most frequently identified complication. About 98% did not know that AOMI is associated with myocardial infarction and stroke, and 93.7% did not know of any complications. Almost all the participants (99.4%) had poor knowledge of the following complications. Conclusion: Obliterative arterial disease of the lower limbs could be prevented or delayed by screening and controlling risk factors. Our results show a huge deficit in knowledge of this pathology, including risk factors, preventive meas

关键词： Obliterative Arterial Disease of the Lower Limbs Knowledge Patients

Clinical and Therapeutic Evaluation of Hypertensives According to the Practice of Ambulatory Blood Pressure Measurement (ABPM) at the Bel Air International Clinic in Conakry from January 1, 2019 to November 30, 2022

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World Journal of Cardiovascular Diseases 2023年第6期13卷 327-332页

作者： Alpha Kone Fousseny Diakite Abel Mansaré Mahamoud Sama Cherif mamadou Bassirou Bah Sana Samoura Souleymane Diakité Ibrahima Sory Barry Ibrahima Sory Sylla Elhadji Yaya baldé Abdoulaye Bangoura Mariame Beavogui mamadou dadhi baldé Mohamed Lamine Kaba Faculty of Health Sciences and Techniques Gamal Abdel Nasser University of Conakry Conakry Guinea Bel Air International Clinic CIBA Conakry Guinea Cardiology Department of Sino-Guinean Hospital Conakry Guinea Donka National Hemodialysis Center Conakry Guinea Cardiology Department of National Hospital Ignace Deen Conakry Guinea

Introduction: Ambulatory Blood Pressure Measurement (ABPM) is a non- invasive examination recommended for subjects at high cardiovascular risk, and those requiring a nocturnal drop in BP such as elderly and obese subjects, those with secondary hypertension or resistant, diabetics, subjects with metabolic syndrome or sleep apnea syndrome. The objective of this study was to evaluate the contribution of ABPM in the diagnosis and evaluation of the level of control of hypertension under treatment at the Bel Air international clinic. Materials and Methods: This is a retrospective, cross-sectional and descriptive study, carried out at the Bel Air International Clinic in Conakry (Guinea) between January 2019 and November 30, 2022. It included a consecutive series of 180 consenting patients recruited through an ambulatory measurement of 24-hour blood pressure from a FUGADA brand device. Results: We collected 180 patients, with a male predominance (sex-ratio M/F = 2.46). The mean age of the patients was 48.48 ± 14.23 years. The most represented age group was that of 32 to 42 years with 50 cases (27.8%) followed by that of 43 to 52 years with 42 cases or 23.3%. The indication was for diagnostic purposes in 106 cases 58.9%, the therapeutic evaluation in 58 patients (32.2%). The examination was prescribed by a cardiologist in 98 cases (54.4%), a general practitioner in 71 cases (39.4%), a neurologist in 11 cases (6.1%). In the therapeutic evaluation, high blood pressure was controlled in 24 patients (13.3%) and uncontrolled in 34 cases (18.9%). In the diagnostic indication, high blood pressure was confirmed in 79 cases (43.9%) with a statistically significant link (Chi2 = 4.57 and p-value = 0.032). The nycthemeral mean was 187.27 ± 26.22 mmHg for systolic blood pressure (SBP) and 110.37 ± 19.06 mmHg for diastolic blood pressure (DBP), during the day, 151.64 ± 21.45 mmHg for SBP and 71.59 ± 8.67 mmHg for diastolic blood pressure. During the study 65 patients (36.1%) were id

关键词： Ambulatory Blood Pressure Measurement Guinea

Prevalence and Contributing Factors of Orthostatic Hypotension in the Cardiology Department of the CHU Ignace Deen in Conakry

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World Journal of Cardiovascular Diseases 2023年第3期13卷 181-187页

作者： Ibrahima Sory Barry El Hadj Yaya baldé Ahmed Youssouf Djiba Mariama Béavogui mamadou Bassirou Mariama Bah Morlaye Soumaoro Abdoulaye Camara Aly Samoura Diarra Koïvogui Kokoulo Koïvogui Salématou Diallo Ibrahima Kalil Tounkara Ousmane Djénaba Savané mamadou dadhi baldé Department of Cardiology CHU Ignace Deen Conakry Guinea

Introduction: Orthostatic Hypotension (OH) is a frequent situation during consultation in hypertensive patients. The prevalence in the general population increases with age and it is recommended to systematically search for it in patients with multiple comorbidities. The objective of this study was to determine the prevalence of orthostatic hypotension;describe their socio- demographic profile, the various clinical and paraclinical aspects and the predisposing factors of orthostatic hypotension in treated hypertensives, controlled or not. Method: This was a descriptive cross-sectional study, from January 2 to June 30, 2022 in the cardiology department of the Ignace Deen National Hospital. Included in this study were all patients who presented with orthostatic hypotension under antihypertensive treatment, regardless of age and sex, and who agreed to participate in the study. The non-inclusion criteria were hypertensive patients without OH and those who had not agreed to participate in the study. Each patient had blood pressure and heart rate measured in the supine position at room temperature and with an empty bladder. Then the measurement is taken again three (3) minutes after the switch to orthostatism. We retained the diagnosis of OH if the SBP drops by at least 20 mmHg and/or the PAD by at least 10 mmHg three (3) min after the transition to orthostatism. Our data obtained were analyzed in the Epi-info 7.4.0 software. Results: During our study period, we investigated 385 presented with OH, 12.2%. The mean age of the patients was 60.83 years ± 10.01 years and hypertensive patients, 47 of whom the M/F sex ratio was 0.81. In our study, blood pressure was not controlled in 36.2% of our patients with a predominance of grade 3 hypertension, a rate of 55.32%. Renal failure, anemia, heart failure and stroke were the main comorbidities associated with the occurrence of HO. The most incriminated factors were age with a frequency of 74.47%, followed by obesity at 44.68% and

关键词： Orthostatic Hypotension Contributing Factors Conakry

Ruptured Sub-Annular Mitral Aneurysm in the Pericardium: Report of a Case

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World Journal of Cardiovascular Diseases 2021年第9期11卷 458-463页

作者： Elhadj Yaya baldé mamadou Bassirou Bah Amadou Djouldé Doumbouya Aissatou Tiguidanké baldé mamadou Cellou Guissé Ibrahima Sory Barry Alpha Koné Mariam Béavogui Souleymane Diakité Ibrahima Sory 2 Sylla mamadou Aliou baldé Abdoulaye Camara mamadou Diallo Thierno Siradjo baldé mamadou dadhi baldé Mamady Condé Cardiology Department of the Ignace Deen Hospital Conakry Guinea Cardiology Department of Donka Hospital Conakry Guinea

The sub-mitral annular aneurysm is a rare cardiac pathology. The etiologies are diverse, ranging from the congenital form to the idiopathic form, including the acquired form. The clinical case we report is that of a 27-year-old young man, with no particular history, admitted with a picture of global heart failure. A cardiac ultrasound diagnosed a ruptured mitral sub-annular aneurysm in the pericardium. The difficulty lies in the surgical management of this condition, due to the lack of an adequate cardiac surgery service in most of the countries in Africa south of the Sahara.

关键词： Sub-Annular Aneurysm Mitral Valve Intrapericardial Rupture

Evaluation of the Knowledge, Attitudes and Practices of the Hospital Staff in the Management of High Blood Pressure in Conakry

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World Journal of Cardiovascular Diseases 2019年第5期9卷 354-359页

作者： Ibrahima Sory 2 Sylla Djibril Sylla Elhadj Yaya baldé Aissatou Barry Mabintou Condé mamadou Bachir Bah mamadou Aliou baldé Sana Samoura Ibrahima Sory Barry Mariame Béaovogui mamadou dadhi baldé Mamadi Condé Cardiology Department Hospital Conakry Conakry Guinea Medico-Surgical Emergencies Department Hospital Donka Conakry Guinea

Introduction: High blood pressure is a real public health problem affecting more than one in three adults. The objective of this study was to evaluate the level of knowledge, attitudes and practices of health care personnel in the management of hypertension in Conakry. Methods: Descriptive transversal study of 6 months, from April 20, 2018 to September 20, 2018, which took place in the internal medicine departments of the two university hospital centers (CHU) of Conakry (Donka and Ignace Deen). The study population consisted of general practitioners and specialists, practicing in both departments for at least two years and who agreed to submit to our questionnaire. Results: At the end of the study, we included 140 doctors, 61% at Donka University Hospital and 39% at Ignace Deen University Hospital. The predominance was male with 113 men for 27 women with a sex ratio H/F = 4.18. General practitioners were the most represented with 95% against 5% specialists. Sixty-four percent of physicians gave an exact definition of hypertension, 56% of physicians confirmed the diagnosis of hypertension after 2 to 3 consultations. 19% offered monotherapy as first-line treatment, only 72% said that the duration of Antihypertensive treatment was for life. Conclusion: Theseresults demonstrate that it is essential to reflect on our daily practices for a good improvement in the quality of care for patients.

关键词： High Blood Pressure Knowledge Attitudes and Practices Conakry

Prevalence of Diabetes and Hypertension on World Diabetes Day 2022 in Guinea

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Open Journal of Endocrine and Metabolic Diseases 2024年第1期14卷 1-6页

作者： mamadou Dian Mamoudou Diallo mamadou Mansour Diallo mamadou Chérif Diallo mamadou Alpha Diallo Alpha mamadou Diallo Mody Abdoulaye Barry Kadija Dieng Abdoul Mazid Diallo El’Hadj Zainoul Bah Kadidiatou Bah Amatoulaye Diallo Amadou Kaké Naby Moussa baldé Oumou baldé Unité de Diabétologie H&#244pital régional de Labé Labe Guinea Université de Conakry Conakry Guinea Service de Diabétologie CHU Donka Conakry Guinea Fondation de Lutte Contre le diabète et MNT Conakry Guinea

Introduction: Diabetes mellitus and hypertension are chronic diseases that are on the rise and pose a major public health problem among the priorities of healthcare systems. Objectives: Determine the prevalence of diabetes and hypertension and describe the sociodemographic characteristics of those screened. Materials and Methods: This was a cross-sectional study organized during a diabetes and hypertension screening campaign that took place in Conakry and five (05) inland regions on November 14, 2022. Results: 2050 people were screened, of whom 33.12% were housewives, the average age was 44.78 ± 16.23 years, and 55.27% were women. The screening sites were the city of Conakry 741 (36.15%), the Labé region 424 (20.68%), the N’Zérékoré region 298 (14.54%), the Faranah region 241 (11.75%), the Mamou region 210 (10.24%) and the Boké region 136 (6.63%). The prevalence of diabetes and hypertension were respectively 12.5% and 43.38% for the Boké region;6.19% and 16.19% for the Mamou region;3.02% and 21.81% for the N’Zérékoré region;31.95% and 13.69% for the Faranah region;9.67% and 20.28% for the Labé region;2.83% and 20.28% for the city of Conakry. Conclusion: Despite the limitations of the study duration, our series highlighted the high prevalence of diabetes and hypertension among people screened on World Diabetes Day 2022. Raising public awareness of a healthy lifestyle is essential for the prevention and control of diabetes and hypertension.

关键词： Prevalence Diabetes Hypertension