检索结果-南通市图书馆

Flow cytometry and stroke: from current methodology to future applications

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2022年第8期17卷 1748-1750页

作者： Sylvie Amu Kyle malone Cancer Research@UCC University College CorkCorkIreland Department of Pharmacology and Therapeutics Western Gateway BuildingUniversity College CorkCorkIreland School of Pharmacy University College CorkCorkIreland

Flow cytometry is a versatile technique for analyzing stroke-induced changes in the immune *** other methods of cell identification such as immunohistochemistry,the technique is rapid,highly sensitive,and capable of quantifying multiple markers in cell *** cell sorters,flow cytometers can also produce highly enriched populations of viable cells for functional *** aim of this perspective is to appraise current flow cytometry methods in the field of stroke,provide guidance on best practices,and outline some of the future applications of the technique in pre-clinical and clinical stroke research.

关键词： viable Flow versatile

Conceptual design of distillation systems

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Characteristics of Water Infiltration in Layered Water-Repellent Soils

丛书名： McGraw-Hill chemical engineering series

2001年

作者： M.F. Doherty and M.F. malone.

来源：畅想之星图书光盘版（南... 评论

在线全文

畅想之星图书光盘版（南通市图书馆镜像）

学校读者我要写书评

暂无评论

Pedosphere 2018年第5期28卷 775-792页

作者： LI Yi REN Xin Robert HILL Robert malone ZHAO Ying College of Water Resources and Architecture Engineering Northwest A&F University Key Laboratory of Agricultural Soil and Water Engineering in Arid and Semiarid Areas Ministry of EducationNorthwest A&F University Department of Environmental Science and Technology University of Maryland USDA-ARS National Laboratory for Agriculture and the Environment Key Laboratory of Plant Nutrition and the Agri-environment in Northwest China Ministry of AgricultureNorthwest A&F University

Water-repellent(WR) soil greatly influences infiltration behavior. This research determined the impacts of WR levels of silt loam soil layer during infiltration. Three column scenarios were utilized, including homogeneous wettable silt loam or sand, silt loam over sand(silt loam/sand), and sand over silt loam(sand/silt loam). A 5-cm thick silt loam soil layer was placed either at the soil surface or 5 cm below the soil surface. The silt loam soil used had been treated to produce different WR levels, wettable, slightly WR, strongly WR, and severely WR. As the WR level increased from wettable to severely WR, the cumulative infiltration decreased. Traditional wetting front-related equations did not adequately describe the infiltration rate and time relationships for layered WR soils. The Kostiakov equation provided a good fit for the first infiltration stage. Average infiltration rates for wettable, slightly WR, strongly WR, and severely WR during the 2 nd infiltration stage were 0.126, 0.021, 0.002, and 0.001 mm min^(-1) for the silt loam/sand scenario,respectively, and 0.112, 0.003, 0.002, and 0.000 5 mm min^(-1) for the sand/silt loam scenario, respectively. Pseudo-saturation phenomena occurred when visually examining the wetting fronts and from the apparent changes in water content(?θ_(AP)) at the slightly WR,strongly WR, and severely WR levels for the silt loam/sand scenario. Much larger ?θAPvalues indicated the possible existence of finger flow. Delayed water penetration into the surface soil for the strongly WR level in the silt loam/sand scenario suggested negative water heads with infiltration times longer than 10 min. The silt loam/sand soil layers produced sharp transition zones of water content. The WR level of the silt loam soil layer had greater effects on infiltration than the layer position in the column.

关键词： infiltration model layered soils ponded infiltration experiment pseudo-saturation soil water content soil water move-ment soil water repellency water drop penetration time

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

磁铁

Breast-to-brain metastasis: a focus on the premetastatic niche

丛书名：外研社点读书

2011年

作者： (美)Pat malone

来源：畅想之星图书光盘版（南... 评论

在线全文

畅想之星图书光盘版（南通市图书馆镜像）

学校读者我要写书评

暂无评论

Journal of Cancer Metastasis and Treatment 2021年第1期7卷 551-568页

作者： Kathryn malone Stella E.Tsirka Department of Pharmacological Sciences Renaissance School of Medicine at Stony Brook UniversityStony BrookNY 11794-8651USA.

Metastatic disease is the cause for 90%of breast cancer *** those 10%-20%of patients whose breast cancer metastasizes to the central nervous system,the one-year survival rate is just 20%.Both histology and molecular subtype have a correlation with the site of tumor metastasis,indicating an inherent preferential aspect to metastatic colony *** molecular differences between breast cancers may determine the site of metastasis through priming of the premetastatic niche in that site:cell surface molecules,exosomes released from the primary tumor,and soluble factors secreted from both the primary tumor and resident cells within the premetastatic niche all contribute to altering the premetastatic niche to be more favorable for the circulating tumor cells,allowing for cell invasion and ***,we review breast to brain metastasis with a focus on the premetastatic *** discuss the secreted factors and exosomes that prime the premetastatic niche within the brain by instigating crosstalk between the resident cells of the brain *** report on the individual roles that microglia,astrocytes,pericytes,neurons,and endothelial cells may have in the formation and maintenance of the premetastatic niche.

关键词： Niche metastasis breast cancer brain

The Use of Nostalgic Material in the Work of Hayao Miyazaki

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The Use of Nostalgic Material in the Work of Hayao Miyazaki

作者： malone Hannah Louise 中国美术学院

学位级别：硕士

宫崎骏(1941-),日本导演、动画师,动画工作室吉卜力工作室的创始人之一。宫崎骏因其动画中创造的令人大开眼界的视觉世界而受到世界的推崇,他将魔幻和怀旧作为救赎的主题,改变了人们对动画作用的认识及其在当代艺术世界中所扮演的角色... 详细信息

宫崎骏(1941-),日本导演、动画师,动画工作室吉卜力工作室的创始人之一。宫崎骏因其动画中创造的令人大开眼界的视觉世界而受到世界的推崇,他将魔幻和怀旧作为救赎的主题,改变了人们对动画作用的认识及其在当代艺术世界中所扮演的角色。现有的关于宫崎骏作品的文献和资料都将关注点缩小到对其导演电影的批判性分析上,却忽略了其以个人经验和怀旧作为内容的叙事。虽然有少量文章涉足了宫崎骏的过去与他的作品之间的关联,但很少有文章对他将记忆作为作品创作的工具进行详细的阐释。本文旨在弥补宫崎骏借助个人经验和令人怀旧的内容来叙事的方法的研究空白。本文还旨在探讨宫崎骏如何在其电影中使用个人记忆创造怀旧内容的具体例子,以及宫崎骏作品之前日本浮世绘和中国连环画中的东亚传统艺术。

关键词：宫崎骏宫崎骏怀旧恢复性怀旧反思性怀旧动画记忆力

同方学位论文库评论

在线全文

同方学位论文库

学校读者我要写书评

暂无评论

每一天都要努力

新东方英语 2004年第1M期 87-89页

作者： Karl malone 张梦华

绰号“邮差”的 NBA 巨星卡尔·马龙,在篮球场上的飒爽英姿为世人所赞叹。但就如大多数的成功人士一样,他的职业篮球之路也充满了曲折与艰辛。他用自己坚定的信念创造了今日的辉煌,他所坚信的就是:做人每一天都要努力!

关键词：大学英语双语阅读对照读物篮球明星

Ecologically Inspired Water Network Optimization of Steel Manufacture Using Constructed Wetlands as a Wastewater Treatment Process

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Engineering 2018年第4期4卷 567-573页

作者： Kaili Zhang Stephen M. malone Bert Bras Marc Weissburg Yuehong Zhao Hongbin Cao Institute of Process Engineering Chinese Academy of Sciences Beijing 100190 China The George W. Woodruff School of Mechanical Engineering Georgia Institute of Technology Atlanta GA 30332 USA School of Biological Sciences Georgia Institute of Technology Atlanta GA 30332 USA

Traditional optimization models often lack a systems-level perspective at conception, which limits their effectiveness. Expanding system boundaries allow scientists and engineers to model complex interactions more accurately, leading to higher efficiency and profitability in industrial systems. Ecological systems have evolved for billions of years under conditions of material and energy shortage, and ecologists have defined analysis tools and metrics for identifying important principles. These principles may provide the framework to circumvent the limitations of traditional optimization techniques. More specifically, by recruiting functional roles that are often found in ecological systems, but are absent in industrial systems, industries can better mimic how natural systems organize themselves. The objective of this analysis is to traditionally optimize a manufacturing process by comparing the model with ecological and resource-based performance metrics in order to redesign the model with the addition of important functional roles that are found throughout nature. Industry partners provided data for this analysis, which involved building a water network for an existing steel manufacturing facility in China. The results of the traditional optimization model indicate a 23%, 29%, and 20% decline in freshwater consumption, wastewater discharge, and total annual cost, respectively. However, our ecologically inspired optimization model provides an additional 21% and 25% decline in freshwater consumption and total annual cost, respectively. Furthermore, no water is discharged. These results suggest that this unconventional approach to optimization could provide an effective technique not used by existing algorithms to solve the challenging problem of pursuing more sustainable industrial systems.

关键词： Phytoremediation Wastewater Steel manufacture Optimization

Unmixing detrital zircon U-Pb ages reveals tectonic and climatic depositional influences on the Carboniferous Ansilta Formation,Calingasta-Uspallata Basin,Western Argentina

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Geoscience Frontiers 2024年第4期15卷 61-77页

作者： J.R.malone J.E.malone J.L.Isbell D.H.malone J.P.Craddock K.N.Pauls Department of Geological Sciences Jackson School of GeosciencesUniversity of Texas at AustinAustinTX 78712USA Iowa Geological Survey University of IowaIowa CityIA 52240USA Department of Geosciences University of Wisconsin-MilwaukeeMilwaukeeWI 53211USA Department of Geography Geology and the EnvironmentIllinois State UniversityNormalIL 61790-4400USA

The Late Paleozoic Ice Age(LPIA)was a principal control of sedimentation across Gondwana from the late Devonian through early *** assess the hypothesis that glacial to interglacial transitions in western Argentina were the primary control influencing sediment routing patterns among the various Carboniferous-Permian basins in western *** Carboniferous Ansilta Formation consists of glaciomarine,nearshore,and fluvial systems deposited during the LPIA along the eastern margin of the Calingasta-Uspallata Basin in *** lower,glacially influenced succession of the Ansilta Formation records at least five glacial advances;the upper succession of consists of progradational shallow marine,deltaic,and fluvial *** combine 1225 new U-Pb zircon ages from six samples of the Carboniferous Ansilta Formation in the Calingasta-Uspallata Basin with 5864 U-Pb ages from 147 pub-lished samples in the detrital Pymix forward mixture model to characterize provenance *** the glacially influenced lower Ansilta Formation,sediment was derived locally from the Protoprecordillera,which was a prominent highland with alpine glaciers flowing west and east into the Calingasta-Uspallata and Paganzo basins,***,there was little or no connection between these two basins during Serpukhovian-Bashkirian *** fluvial/deltaic upper Ansilta had distal sediment sources in the Sierras ***,our results support the collapse of the Protoprecordillera topographic barrier,enabling drainage patterns connecting the Paganzo and Calingasta-Uspallata basins by late Pennsylvanian-early Permian time.

关键词： Late Paleozoic Ice Age Argentina Calingasta-Uspallata Basin Ansilta Formation Detrital zircon provenance