检索结果-南通市图书馆

COVID-19 mutations:An overview

在线全文

学校读者我要写书评

暂无评论

World Journal of Methodology 2024年第3期14卷 7-22页

作者： malay Sarkar Irappa Madabhavi Department of Pulmonary Medicine Indira Gandhi Medical CollegeShimla 171001Himachal PradeshIndia Department of Medical and Pediatric Oncology and Hematology J N Medical Collegeand KAHERBelagaviKarnataka 590010India Department of Medical and Pediatric Oncology and Hematology Kerudi Cancer HospitalBagalkotKarnataka 587103India

The severe acute respiratory syndrome coronavirus-2(SARS-CoV-2)belongs to the genus Beta coronavirus and the family of *** is a positive-sense,non-segmented single-strand RNA *** common types of human coronaviruses circulate globally,particularly in the fall and winter *** are responsible for 10%-30% of all mild upper respiratory tract infections in *** are 229E,NL63 of the Alfacoronaviridae family,OC43,and HkU1 of the Betacoronaviridae ***,there are three highly pathogenic human coronaviruses:SARS-CoV-2,Middle East respiratory syndrome coronavirus,and the latest pandemic caused by the SARS-CoV-2 *** viruses,including SARS-CoV-2,have the inherent tendency to ***-CoV-2 is still evolving in ***,due to the development of herd immunity,prior infection,use of medication,vaccination,and antibodies,the viruses are facing immune *** the replication process and due to immune pressure,the virus may undergo *** SARS-CoV-2 variants,including the variants of concern(VOCs),such as B.1.1.7(Alpha),B.1.351(Beta),B.1.617/B.1.617.2(Delta),P.1(Gamma),and B.1.1.529(Omicron)have been reported from various parts of the *** VOCs contain several important mutations;some of them are on the spike *** mutations may lead to enhanced infectivity,transmissibility,and decreased neutralization efficacy by monoclonal antibodies,convalescent sera,or *** may also lead to a failure of detection by molecular diagnostic tests,leading to a delayed diagnosis,increased community spread,and delayed *** searched PubMed,EMBASE,Covariant,the Stanford variant Database,and the CINAHL from December 2019 to February 2023 using the following search terms:VOC,SARS-CoV-2,Omicron,mutations in SARS-CoV-2,*** review discusses the various mutations and their impact on infectivity,transmissibility,and neutralization efficacy.

关键词： Variant of concern SARS-CoV-2 Omicron N501Y mutation E484k mutation

Brewing and biochemical characterization of Camellia japonica petal wine with comprehensive discussion on metabolomics

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Food Production, Processing and Nutrition 2022年第1期4卷 366-382页

作者： Soumya Majumder Arindam ghosh Sourav Chakraborty malay Bhattacharya Molecular Biology and Tissue Culture Laboratory Department of Tea ScienceUniversity of North BengalSiliguriDarjeelingWest Bengal 734013India Postgraduate Department of Botany Darjeeling Government CollegeDarjeelingWest Bengal 734101India

A novel wine has been developed from Camellia japonica’s petal by fermenting the decoction with Saccharomyces cerevisiae or brewer’s yeast. pH, brix, specific gravity and alcohol percentage were tested to study the physicochemical properties of the wine. Qualitative tests indicated presence of phenols such as flavonoids, coumarins;protein;glyco-sides;glycerin;terpenoids;steroids;and fatty acids in the wine. Total phenol content was found high in the decoction and in its fermented form as well. In vitro biological activities such as antioxidant activity, antidiabetic activity and lipid peroxidation inhibition power were assessed in samples. Furthermore, GC-MS analysis helped to detect volatiles present in the unfermented decoction and understand the effect of fermentation on its changing metabolome while column chromatography assisted the separation of solvent-based fractions. Notable outcomes from this study were detection of bioactive compound quinic acid in the decoction and a proposed pathway of its metabolic breakdown after fermentation. Results of this research revealed biochemical and physicochemical acceptability of this wine prepared from an underutilized flower.

关键词： Camellia Quinic acid GC-MS Fermentation Wine

General relativistic calculations for white dwarfs

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Research in Astronomy and Astrophysics 2017年第6期17卷 107-116页

作者： Arun Mathew malay k. Nandy Department of Physics Indian Institute of Technology Guwahati Guwahati 781 039 India

The mass-radius relations for white dwarfs are investigated by solving the Newtonian as well as Tolman-Oppenheimer-Volkoff （TOV） equations for hydrostatic equilibrium assuming the electron gas to be non-interacting. We find that the Newtonian limiting mass of 1.4562 M is modified to 1.4166 M in the general relativistic case for 4He （and 12 6C） white dwarfs. Using the same general relativistic treatment, the critical mass for 56 26Fe white dwarfs is obtained as 1.2230 M. In addition, departure from the ideal degenerate equation of state （EoS） is accounted for by considering Salpeter＇s EoS along with the TOV equation, yielding slightly lower values for the critical masses, namely 1.4081 M for 4He, 1.3916M for 12C and 1.1565M for 56 26Fe white dwarfs. We also compare the critical densities for gravitational instability with the neutronization threshold densities to find that 4 2He and 12 6C white dwarfs are stable against neutronization with the critical values of 1.4081 M and 1.3916 M, respectively. However, the critical masses for 16 8O, 20 10Ne, 24 12Mg, 28 14Si,32 16S and 56 26Fewhite dwarfs are 26Fe white lower due to neutronization. Corresponding to their central densities for neutronization thresholds, we obtain their maximum stable masses due to neutronization by solving the TOV equation coupled with the Salpeter EoS.

关键词： equation of state - hydrodynamics-instabilities - relativistic processes - stars whitedwarfs

Noncommutative dispersion relation and mass-radius relation of white dwarfs

在线全文

学校读者我要写书评

暂无评论

Research in Astronomy and Astrophysics 2018年第12期18卷 75-88页

作者： Arun Mathew malay k.Nandy Department of Physics Indian Institute of Technology Guwahati

The equation of state of the electron degenerate gas in a white dwarf is usually treated by employing the ideal dispersion ***, the effect of quantum gravity is expected to be inevitably present and when this effect is considered through a non-commutative formulation, the dispersion relation undergoes a substantial *** this paper, we take such a modified dispersion relation and find the corresponding equation of state for the degenerate electron gas in white *** we solve the equation of hydrostatic equilibrium and find that this leads to the possibility of the existence of excessively high values of masses exceeding the Chandrasekhar limit, although the quantum gravity effect is taken to be very *** is only when we impose the additional effect of neutronization that we obtain white dwarfs with masses close to the Chandrasekhar limit with nonzero radii at the neutronization *** demonstrate these results by giving numerical estimates for the masses and radii of helium, carbon and oxygen white dwarfs.

关键词： gravitation equation of state stars:white dwarfs

2,4-D Hyper Accumulation Induced Cellular Responses of Azolla pinnata R. Br. to Sustain Herbicidal Stress

在线全文

学校读者我要写书评

暂无评论

Phyton-International Journal of Experimental Botany 2020年第4期89卷 999-1017页

作者： Arnab kumar De Arijit ghosh Debabrata Dolui Indraneel Saha malay kumar Adak Plant Physiology and Plant Molecular Biology Research Unit Department of BotanyUniversity of KalyaniWest BengalIndia

In the present experiment with ongoing concentration(0µM,100µM,250µM,500µM and 1000µM)of 2,4-D,the responses of Azolla pinnata *** evaluated based on cellular ***,plants were significantly tolerated up to 1000µM of 2,4-D with its *** was accompanied by a steady decline of indole acetic acid(IAA)concentration in tissues with 78.8%over the *** bound H^(+)-ATPase activity was over expressed within a range of 1.14 to 1.25 folds with activator(kCl)and decreased within a range of 57.3 to 74.6%in response to inhibitor(Vanadate)*** regards to IAA metabolism,plants recorded a linear increase with wall bound oxidase activity up to maximum concentration of 2,*** variations were more moderated when wall bound IAA-oxidase recorded a linear increase proportionate to the 2,4-D *** was more extended with the presence of different isoforms of IAA-oxidase which was much more pronounced with distinct polymorphisms of expressed proteins,however,not independent to the 2,4-D *** like spermine,spermidine and putrescine(spm,spd and put)were not consistent in concentration with the dosages of 2,*** these,plants were induced to apoplastic NAD(P)H oxidase activity maximally by 1.6 folds under 500µM 2,4-D over ***,putrescine responded more or less consistently and recorded maximally 11.9 folds at 500µM 2,4-D as compared to the ***(P)H oxidase activity recorded maximally 1.6 folds against control and remain consistent throughout the concentrations of 2,*** along with APX were more linear in responses through the concentration of 2,4-D except CAT as compared to *** enzymatic antioxidative activity,peroxidases(GPX and APX)were overexpresed in a similar manner except for catalase with a non-significant *** stabilization of cellular redox,glutathione reductase attended maximum value by 2.45 folds at 1000µM evidenced with significant variations in protein polymo

关键词： Azolla 2,4-D antioxidative enzymes comet assay HPLC

Production of fermented tea petal decoction with insights into in vitrobiochemical tests,antioxidant assay and GC-MS analysis

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Food Production, Processing and Nutrition 2021年第1期3卷 406-415页

作者： Soumya Majumder Sumedha Saha Arindam ghosh Sukanya Acharyya Sahadeb Sarkar Sourav Chakraborty malay Bhattacharya Molecular Biology and Tissue Culture Laboratory Department of Tea ScienceUniversity of North BengalSiliguriDarjeelingWest Bengal Pin-734013India

This research work was designed to attempt and propose the first report on production and biochemical characterization of fermented tea flower petal decoction or simply tea petal *** tea petal decoction and brewer’s yeast or Saccharomyces cerevisiae were co-cultured for *** activity and chromatographic separation of potential candidates were *** investigations for qualitative characters on this fermented broth revealed the presence of steroids,tannin,flavonoids,phenol,cardiac glycosides,coumarin,caffeine *** manufactured fermented broth showed high free radical scavenging activity after 2 months of *** DPPH scavenging activities were also observed in solvent fractions of acetone,ethanol and *** antioxidant activity,alcohol percentage and other qualities were seen to be gradually increased during *** chromatography-mass spectrometry analysis revealed the presence of 44 compounds including many potential antioxidant molecules and other bioactive ***,presence of alcohol with medicinally active compounds and antioxidant activity will make it as acceptable as a good wine and tea flower as economically functional.

关键词： Tea petal Antioxidant GC-MS Fermentation brewer’s yeast

Impeded Carbohydrate Metabolism in Rice Plants under Submergence Stress

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Rice science 2011年第2期18卷 116-126页

作者： malay kumar ADAk Nirmalya ghosh Dilip kumar DASGUPTA Sudha GUPTA Plant Physiology and Plant Molecular Biology Research Unit Department of Botany University of Kalyani Department of Crop Physiology University of Calcutta

The detrimental effects of submergence on physiological performances of some rice varieties with special references to carbohydrate metabolisms and their allied enzymes during post-flowering stages have been documented and clarified in the present investigation. It was found that photosynthetic rate and concomitant translocation of sugars into the panicles were both related to the yield. The detrimental effects of the complete submergence were recorded in generation of sucrose, starch, sucrose phosphate synthase and phosphorylase activity in the developing panicles of the plants as compared to those under normal or control （i.e. non-submerged） condition. The accumulation of starch was significantly lower in plants under submergence and that was correlated with ADP-glucose pyrophosphorylase activity. Photosynthetic rate was most affected under submergence in varying days of post-flowering and was also related to the down regulation of Ribulose bisphosphate carboxylase activity. However, under normal or control condition, there recorded a steady maintenance of photosynthetic rate at the post-flowering stages and significantly higher values of Ribulose bisphosphate carboxylase activity. Still, photosynthetic rate of the plants under both control and submerged conditions had hardly any significant correlation with sugar accumulation and other enzymes of carbohydrate metabolism like invertase with grain yield. Finally, plants under submergence suffered significant loss of yield by poor grain filling which was related to impeded carbohydrate metabolism in the tissues. It is evident that loss of yield under submergence is attributed both by lower sink size or sink capacity （number of panicles, in this case） as well as subdued carbohydrate metabolism in plants and its subsequent partitioning into the grains.

关键词： photosynthesis sucrose starch phosphorylase grain yield rice submergence

Elicitation-Based Modulation of Shelf Life in Fruits: Physiological and Molecular Insights

在线全文

学校读者我要写书评

暂无评论

Phyton-International Journal of Experimental Botany 2023年第8期92卷 2283-2300页

作者： Ankita kundu Abir Das Sayan Pal Arijit ghosh malay kumar Adak Masayuki Fujita Mirza Hasanuzzaman Plant Physiology and Molecular Biology Research Unit Department of BotanyUniversity of KalyaniKalyani741235India Laboratory of Plant Stress Responses Faculty of AgricultureKagawa UniversityKagawa761-0795Japan Department of Agronomy Faculty of AgricultureSher-E-Bangla Agricultural UniversityDhaka1207Bangladesh

The process of ripening involves physiological and biochemical events that become a concern during postharvest *** have documented different approaches for the preservation and maintenance of fruit quality during the postharvest period that are biocompatible and fully safe for *** residues that sustain sensory characteristics,such as color,ﬂavor,aroma,and texture,are *** fruit ripening,both physical and chemical elicitors are described that regulate ethylene biosynthesis or its signaling for gene *** key regulatory enzymes,such as ACC synthase and ACC oxidase,for ethylene biosynthesis,are important for both climacteric and non-climacteric ***-oxidizing genes that retain sensory characteristics are concerns in this *** elicitors,including chitosan,polyamine,phenolics,lipopolysaccharide,silver derivatives,and nanocomposites,are *** pressure,light wavelengths,relative humidity,cooling,and other environmental factors are important for improved postharvest *** elicitors maintain redox status by inhibiting the generation of reactive oxygen species(ROS)or their *** regulators,including abscisic acid,auxin,brassinosteroids,jasmonic acid,and salicylic acid,are important for the regulation of *** injuries,ionic imbalances,temperature variations,and tissue dehydration can occur irrespective of ripening *** use of synthetic physiochemically active compounds is discussed in terms of physiological,metabolic,cellular,and molecular ***-induced autocatalytic processes,antioxidant cascades,epigenetic regulation,and homeodomain gene expression are ***–acid metabolism,dissolution of the cell wall,and direct or indirect production of secondary metabolites related to postharvest storage are mentioned regarding chilling *** and agrochemicals that trigger plant defense to increase secondary metabolite production are discussed fo

关键词： Epigenetics ethylene elicitors ripening polyphenolics postharvest storage

Medicine prescription practices of homeopathic undergraduate students in West Bengal,India

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Integrative Medicine 2014年第1期12卷 7-12页

作者： Subhranil Saha Munmun koley Jogendra Singh Arya Gurudev Choubey Shubhamoy ghosh Subhasish Ganguly Aloke ghosh Sangita Saha malay Mundle Clinical Research Unit(Homeopathy) Siliguri 734006DarjeelingWest BengalIndia under Central Council for Research in Homeopathy Government of India Department of Pathology and Microbiology Mahesh Bhattacharyya Homeopathic Medical College and Hospital Department of Organon of Medicine and Homeopathic Philosophy D N De Homeopathic Medical College and Hospital Department of Organon of Medicine and Homeopathic Philosophy Midnapore Homeopathic Medical College and Hospital Department of Organon of Medicine and Homeopathic Philosophy Calcutta Homeopathic Medical College and Hospital Department of Community Medicine Medical College of Kolkata

OBJECTIVE： To our knowledge, prescription of homeopathic medicines by homeopathic undergraduate students has not been studied before though it may possess serious implications. We aimed to determine the practice and attitudes of prescription by homeopathic undergraduate students. METHODS： A cross-sectional study was carried out involving all the students from four government homeopathic schools of West Bengal, India. Ethical requirements were ensured and data were collected using self-administered questionnaires. Chi-square tests and logistic univariate regression analyses were performed to identify associations and differences. RESULTS： A total of 328 forms were completed. Of these, 264 （80.5%） homeopathic undergraduate students admitted of prescribing medicines independently and most （40.5%） said that they did this 2-3 times a year. The most common reasons for this were ＇urgency of the problem＇（35.2%）, ＇previous experience with same kind of illness＇（31.8%）, and ＇the problem too trivial to go to a doctor＇（25.8%）. About 63.4% of the students thought that it was alright to independently diagnose an illness while 51.2% thought that it was alright for them to prescribe medicines to others. Common conditions encountered were fever, indigestion, and injury. Students who prescribed medicines were more likely to belong to Calcutta Homeopathic Medical College and Hospital （odds ratio = 5.8; 95% confidence interval 2.247-14.972）. Prescription by students gradually increased with academic years of homeopathic schools. Many students thought it was alright for students to diagnose and treat illnesses. CONCLUSION： Prescription of medicines by homeopathic undergraduate students is quite rampant and corrective measures are warranted.

关键词： homeopathy education, medical, undergraduate India prescriptions, drug practice, institutional drug use, irrational