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The Tower of Hanoi for Evaluating Dysexecutive Syndrome in Patients with Parkinson’s:Standardization Values

Advances in Parkinson's Disease 2017年第3期6卷 75-85页

作者： Marcos serrano-Duenas Belén Calero maite serrano Medicine Faculty Pontifical Catholic University of EcuadorQuitoEcuador Movement Disorders Unit Neurological ServiceCarlos Andrade Marín HospitalQuitoEcuador

Objective: The Tower of Hanoi measures executive functions using non-verbal content and requires perception of position in space. The main objective of this study is to standardize the use of the TOH as a measurement tool in Parkinson’s disease. Patients and Methods: Of the Control Group subjects, 192 (59.6%) were women, 223 subjects (69.25%) were able to perform the TOH with 3 discs. In the Parkinson’s Group, there were 57 women (39.3%), and 66 subjects (45.5%) did not get past that level. Results: If we take the TOH (with 3 or 4 discs) as a tool for discriminating between those who have dysexecutive syndrome and those who do not, we find that the Parkinson’s Group presents dysexecutive syndrome significantly more frequently than the Control Group (p ≤ 0.0064). Conclusion: We can conclude that dysexecutive syndrome is frequent in Parkinson’s patients and it is more prevalent than in the general population.

关键词： Parkinson’s Disease Dysexecutive Syndrome Tower of Hanoi

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Properties of the Apathy Scale(AS)for use on Parkinson’s patients

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Advances in Parkinson's Disease 2013年第2期2卷 53-57页

作者： Marcos serrano-Duenas Pablo Martínez-Martín Tamara Merchán Rosaura Bravo maite serrano Movement Disorder and Biostatistics Units Neurological ServiceCarlos Andrade Marín HospitalQuitoEcuador Medicine Faculty Pontifical Catholic University of EcuadorQuitoEcuador Alzheimer Disease Research Unit CIEN FoundationCarlos III Institute of HealthAlzheimer Center Reina Sofia FoundationMadridSpain

Parkinson’s disease is a neurodegenerative disorder characterized by motor, autonomic, and neuropsychiatric symptoms, among the latter, apathy has been found to be present in up to 70% of patients. The main objective of the present study was to assess the psychometric properties of the Apathy Scale for evaluation of Ecuadorian patients with Parkinson’s. This was a cross sectional study, with re-test. There were 73 women (34.5%) in the final sample of 211 patients. Mean age was 67.5 ± 10.2 years, mean length of illness was 7.1 ± 5.5 years, and the mean ldopa dose was 656.1 ± 292.7 mg/day. The mean Apathy Scale score was 12.7 ± 7.1. Reliability: The Guttman’s λ obtained was 0.89. The SEM was 2.34 for the AS. The ICC using an absolute agreement definition was: ICC = 0.78 [(95% IC 0.73?- 0.82) f = 4.96;p ≤ 0.000]. Discriminative validity, analyzed with the Kruskal-Wallis statistic and using H&Y stages as segmentation variable registered an X(2) value of p 0.0001. In conclusion the Apathy Scale proved to have suitable metric attributes in this specific PD patient sample: internal consistency, reliability, stability, and convergent and known-groups validity.

关键词： Parkinson’s Disease Apathy Associated with Parkinson’s Disease Apathy Scale Metric Properties

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