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Gallbladder drainage guided by endoscopic ultrasound

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World Journal of Gastrointestinal Endoscopy 2010年第6期2卷 203-209页

作者： José Carlos Súbtil maite betes Miguel Muoz-Navas Gastroenterology Department University Clinic of Navarra

The gold-standard management of acute cholecystitis is *** intervention may be contraindicated due to permanent *** date,the classical approach is percutaneous cholecystostomy in patients unresponsive to medical ***, with this treatment some patients may experience discomfort,complications and a decrease in their quality of *** these cases,endoscopic ultrasound (EUS)-guided gallbladder drainage may represent an effective minimally invasive *** objective is to describe in detail this new and not well-known technique:EUS-guided *** will describe how the patient should be prepared,what accessories are needed and how the technique is *** will also discuss the possible indications for this technique and will provide a brief review based on published reports and our own experience.

关键词： Gallbladder drainage Endoscopic ultrasoundguided Cholecystenterostomy Cholecystogastrostomy Cholecystoduodenostomy Percutaneous cholecystostomy Endoscopic transpapillary gallbladder drainage Acute cholecystitis

Primary Analysis of Oceanic Mesoscale Eddies Observation Abilities by Sentinel-3A SRAL

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Journal of Geodesy and Geoinformation Science 2021年第1期4卷 56-62页

作者： Jungang YANG Jie ZHANG Wei CUI Munoz maite Makhoul EDUARD First Institute of Oceanography Ministry of Natural ResourcesQingdao 266061China IsardSAT S.L. Barcelona 08007Spain

In this study,the north-western Pacific Ocean of Kuroshio region is selected as the experimental area to analyze the mesoscale eddies observation abilities of Sentinel-3 A SRAL,including the independent detection abilities of Sentinel-3 A SRAL and the improvement of mesoscale eddies detection abilities by data fusion with other satellite altimetry *** Sentinel-3 A SRAL data are mapped by the spatial-temporal objective analysis method to the sea level anomaly grid *** mapping errors are analyzed by the comparisons between the grid data of different combinations and along the ground track of Jason-2/*** independent detection abilities of Sentinel-3 A SRAL are analyzed by the comparison between the grid data and the AVISO MSLA *** the other hand,through the multi-satellite data fusion of different combinations of Sentinel-3 A altimeter and other satellite altimeters such as Jason-2/3,the mesoscale eddies detection was performed based on the merged sea level anomaly data and the addition of Sentinel-3 A SRAL data for the improvements of mesoscale eddies detection abilities by multi-satellite altimeters are *** is concluded that Sentinel-3 A SRAL has good abilities of mesoscale eddies detection as the combination of Jason-2 and Jason-3,and it is better than that of single altimeter of Jason-2 or Jason-3.

关键词： Sentinel-3 altimeter mesoscale eddy

Does drought stress modify the effects of plant-growth promoting rhizobacteria on an aboveground chewing herbivore？

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Insect Science 2017年第6期24卷 1034-1044页

作者： maite Fernandez de Bobadilla Julia Friman Nurmi Pangesti Marcel Dicke Joop J.A. van Loon Ana Pineda Laboratory of Entomology Wageningen University Wageningen The Netherlands Netherlands Institute of Ecology (NIOO-KNA W) Department of Terrestrial Ecology Wageningen The Netherlands

Soil microbes have important effects on the interactions of plants with their environment, by promoting plant growth, inducing resistance to pests or by conferring tolerance to abiotic stress. However, their effects are variable and the factors responsible for this variation are mainly unknown. Our aim was to assess how drought stress modifies the effect of the nonpathogenic rhizobacterium Pseudomonas simiae WCS417r on plant growth and resistance against the generalist leaf-chewing caterpillar Mamestra brassicae. We studied Arabidopsis tha/iana Col-0 plants, as well as mutants altered in the biosyn- thesis of the phytohormones jasmonic acid （JA） and abscisic acid （ABA）. Caterpillars did not prefer rhizobacteria-treated plants, independently of drought stress. Rhizobacteria colonization had a variable effect on caterpillar performance, which ranged from positive in one experiment to neutral in a second one. Drought had a consistent negative effect on herbivore performance; however, it did not modify the effect of rhizobacteria on herbivore performance. The effect of drought on herbivore performance was JA-mediated （confirmed with the use of the dde2-2 mutant）, but it was still present in the ABA-deficient mutant aba2-1. Plant biomass was reduced by both drought and herbivory but it was enhanced by rhizobacterial colonization. Pseudomonas simiae WCS417r is able to promote plant growth even when plants are suffering herbivory. Nevertheless, the microbial effect on the herbivore is variable, independently of drought stress. To get the best possible outcome from the rhizobacteria-plant mutualism it is important to understand which other factors may be responsible for its context-dependency.

关键词： abiotic stress abscisic acid crosstalk induced systemic resistance jasmonic acid Pseudomonas simiae

Hyperpycnal littoral deltas:A case of study from the Lower Cretaceous Agrio Formation in the Neuquén Basin,Argentina

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Journal of Palaeogeography 2021年第4期10卷 550-570页

作者： Ainara Irastorza Carlos Zavala Debora Mical Campetella Martín Turienzo Daniela Olivera Florencia Peralta maite Irastorza Paula Martz Dpto.de Geología Universidad Nacional Del Sur(UNS)Bahía Blanca 8000Argentina Instituto Geologico Del Sur(INGEOSUR) Universidad Nacional Del Sur(UNS)-CONICETBahía Blanca 8000Argentina GCS Argentina SRL Molina Campos 150Bahía Blanca 8000Argentina Universidad Nacional Del Sur Bahía Blanca 8000Argentina Universidad Nacional de Río Negro.Instituto de Investigacion de Paleobiología y Geología General Roca 8332Río NegroArgentina Consejo Nacional de Investigaciones Científicas y Tecnicas(CONICET) Instituto de Investigaciones en Paleobiología y GeologíaGeneral Roca 8332Río NegroArgentina

Recent advances in the understanding of deltaic deposits provide new tools for the study and analysis of deltaic deposits in shallow epicontinental *** the introduction of sequence stratigraphic concepts,meter-scale coarsening and thickening upward successions have been considered as“parasequences”originated by high-frequency sea-level ***,recent studies enhanced the importance of wave-aided low-dense hyperpycnal flows in transporting fine-grained sediments in shallow shelfal *** poorly-known(and at the same time very common)types of delta,known as hyperpycnal littoral deltas(HLD),develop very low gradient progradational units,controlled by changes in the sediment supply instead of sea level *** small-scale progradational units are very common in shallow epicontinental seas like the Lower Cretaceous Agrio Formation in the Neuquén *** study provides a first detailed analysis of hyperpycnal littoral deltas from the Agua de la Mula Member(upper Hauterivian-lower Barremian)of the Agrio *** unit has been studied in three locations near Bajada del Agrio locality in the central part of the Neuquén Basin,*** sandy facies,three heterolithic facies,three muddy facies and four calcareous facies were *** facies analysis,three facies associations could be determined,corresponding to offshore/prodelta,distal ramp delta and proximal ramp *** three stratigraphic sections discussed in this study are internally composed of several small-scale sequences showing a coarsening and thickening upward pattern,transitionally going from muddy to sandy wave-dominated facies,and ending with calcareous bioclastics levels on *** small-scale sequences are interpreted as delta front deposits of wave-influenced hyperpycnal littoral deltas,punctuated by calcareous intervals accumulated during periods of low sediment *** is interpreted that the development of hyperpycnal littoral deltas could have been

关键词： Deltas Hyperpycnal littoral deltas Prograding sequences Agua de la Mula Member Neuquén Basin

The adjustment of γ-aminobutyric acid_A tonic subunits in Huntington＇s disease：from transcription to translation to synaptic levels into the neostriatum

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Neural Regeneration Research 2018年第4期13卷 584-590页

作者： Abraham Rosas-Arellano Argel Estrada-Mondragón Carola A.Mantellero Carlos Tejeda-Guzmán maite A.Castro Instituto de Bioquimica y Microbiologia Facultad de Ciencias Universidad Austral de Chile Valdivia Chile Center for Interdisciplinary Studies on the Nervous System (CISNe) Universidad Austral de Chile Valdivia Chile Departamento de Fisiologla Biofisica y Neurociencias Cinvestav del IPN Ciudad de Mexico Mexico Queensland Brain Institute The University of Queensland Brisbane Australia Laboratorio de Neurociencias Departamento de Biologia Facultad de Quimica y Biologla Universidad de Santiago de Chile Santiago de Chile Chile

γ-Aminobutyric acid（GABA）,plays a key role in all stages of life,also is considered the main inhibitory *** activates two kind of membrane receptors known as GABAA and GABAB,the first one is responsible to render tonic inhibition by pentameric receptors containing α4-6,β3,δ,or ρ1-3 subunits,they are located at perisynaptic and/or in extrasynaptic *** biophysical properties of GABAA tonic inhibition have been related with cellular protection against excitotoxic injury and cell death in presence of excessive *** this basis,GABAA tonic inhibition has been proposed as a potential target for therapeutic intervention of Huntington＇s ***＇s disease is a neurodegenerative disorder caused by a genetic mutation of the huntingtin *** experimental studies of Huntington＇s disease mouse models have been developed,such as R6/1,R6/2,Hdh Q92,Hdh Q150,as well as *** all of them,some key experimental reports are focused on *** neostriatum is considered as the most important connection between cerebral cortex and basal ganglia structures,its cytology display two pathways called direct and indirect constituted by medium sized spiny neurons expressing dopamine D1 and D2 receptors respectively,they display strong expression of many types of GABAA receptors,including tonic *** studies about of GABAA tonic subunits and Huntington＇s disease into the neostriatum are rising in recent years,suggesting interesting changes in their expression and localization which can be used as a strategy to delay the cellular damage caused by the imbalance between excitation and inhibition,a hallmark of Huntington＇s disease.

关键词： GABAA extrasynaptic and perisynaptic y-aminobutyric acidA receptors striatum R6/1, R6/2,HdhQ92, HdhQ111, HdhQ150, N171-82Q and YAC128 HD transgenics mice models chorea mutanthuntingtin inhibitory neurotransmission D1 medium sized spiny neurons D2 medium sized spiny neurons

Long-term follow-up study of gastroduodenal lesions after radioembolization of hepatic tumors

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World Journal of Gastroenterology 2013年第19期19卷 2935-2940页

作者： Iago Rodríguez-Lago Cristina Carretero maite Herráiz José C Subtil maite Betés Macarena Rodríguez-Fraile Jesús J Sola José I Bilbao Miguel Muoz-Navas Bruno Sangro Endoscopy Unit Department of GastroenterologyUniversity of Navarra Clinic31008 PamplonaNavarraSpain Department of Nuclear Medicine University of Navarra Clinic31008 PamplonaNavarraSpain Department of Pathology University of Navarra Clinic31008 PamplonaNavarraSpain Department of Radiology University of Navarra Clinic31008 PamplonaNavarraSpain Liver Unit University of Navarra Clinic31008 PamplonaNavarraSpain National Biomedical Research Centre Network for Hepatic and Digestive Diseases 08036 BarcelonaCataluaSpain

AIM:To evaluate the long-term natural history of the gastroduodenal lesions secondary to extrahepatic embolization with Ytrium 90(90 Y) ***:From September 2003 to January 2012,379 procedures of liver radioembolization(RE) using resin microspheres loaded with 90 Y were performed in our *** have retrospectively compiled the data from 379 RE procedures performed in our *** report a comprehensive clinical,analytical,endoscopic and histologic long-term follow-up of a series of patients who developed gastroduodenal lesions after the ***:Six patients(1.5%) developed gastrointestinal symptoms and had gastrointestinal lesions as shown by upper endoscopy in the next 12 wk after *** mean time between RE and the appearance of symptoms was 5 *** one patient required endoscopic and surgical *** incidence of gastrointestinal ulcerations was 3.75%(3/80) when only planar images were used for the pre-treatment *** was reduced to 1%(3/299) when singlephoton emission computed tomography(SPECT) images were also *** symptoms that lasted for a longer time were nausea and vomiting,until 25 mo after the ***:All patients were free from severe symptoms at the end of *** routine use of SPECT has decreased the incidence of gastrointestinal lesions due to unintended deployment of 90 Y particles.

关键词： Radioembolization Liver neoplasms Gastroduodenal ulcer Single-photon emission computed tomography Liver

Dispersal behavior of yellowjacket （Vespula germanica） queens

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Insect Science 2018年第1期25卷 109-116页

作者： maite Masciocchi Andres S. Martinez Aria J. Pereira Jose M. Villacide Juan C. Corley CONICET CCT Comahue INTA Grupo de Ecologia de Poblaciones de Insectos INTA EEA Bariloche Argentina Centro Regional Universitario Bariloche U. N. del Comahue Bariloche 8400 Argentina

Understanding the factors that affect animal dispersal behavior is important from both *** and applied perspectives. Dispersal can have clear evolutionary and ecological consequences, but for normative insect pests, dispersal capacity can also help to explain invasion success. Vespula germanica is a social wasp that, in the last century, has successfully invaded several regions of the world, showing one of the highest spread rates reported for a nonnative insect. In contrast with nonsocial wasps, in social species, queens are responsible for population redistribution and spread, as workers are sterile. For V. germanica, it has been observed that queen flight is limited to 2 distinct periods： early autumn, when new queens leave the nest to mate and find sheltered places in which to hibernate, and spring when new colonies are founded. Our aim was to study the flight behavior of V. germanica queens by focusing on the different periods in which dispersal occurs, characterizing as well the potential contribution of queen flight （i.e., distance） to the observed geographical spread. Our results suggest that the distances flown by nonover- wintered queens is greater than that flown by overwintered individuals, suggesting that the main queen dispersal events would occur before queens enter hibernation. This could relate to a behavioral trait of the queens to avoid the inbreeding with related drones. Additionally, given the short distances flown and remarkable geographical spread observed, we provide evidence showing that queen dispersal by flight is likely to contribute proportionately less to population spread than human-aided factors.

关键词： flight potential German wasps hibernation invasive wasps social insect

What Is the Relation between Aerobic Capacity and Physical Activity Level in Adults with Congenital Heart Disease?

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Congenital Heart Disease 2021年第6期16卷 585-595页

作者： Kelly Ferri maite Doñate Mireia Parra Guillermo ROviedo Myriam Guerra-Balic Laia Rojano-Doñate Nicole Blackburn Ricard Serra-Grima FPCEE-Blanquerna Ramon Llull UniversityBarcelonaSpain Cardiology Department Santa Creu and Sant Pau HospitalIIB Sant PauBarcelonaSpain Cors Units Foundation BarcelonaSpain Zoophysiology Department of BiologyAarhus UniversityAarhusDenmark Institute of Nursing and Health Research Ulster UniversityJordanstownNorthern Ireland

Background:Aerobic capacity(AC)in adults with congenital heart disease(CHD)is often reduced,mainly due to low confidence levels towards physical activity(PA).The main objective of this study was to estimate the association between PA level and AC(measured as peak of oxygen consumption,VO_(2peak))in adults with ***:A total of 183 individuals(83 women and 100 men;mean(SD)age 36.9(11.0)years old)from Vall d’Hebron Hospital,Barcelona-Spain in 2019,participated in this cross-sectional *** AC was assessed by cardiopulmonary exercise testing(CPET)using a treadmill ramp *** values of metabolic equivalent of task(MET,MET-min·week-1)obtained by the short International Physical Activity Questionnaire(IPAQ),participants were divided into three categories of PA:health-enhancing PA(HEPA),minimally active,and ***:Median(SD)PA was 2737.2(2835.7)MET-min·week-1,with 60 participants(32.8%)reporting HEPA,91(49.7%)minimally active,and 32(17.5%)*** demonstrated a mean VO_(2peak) of 28.9(8.8)mL·Kg^(-1)·min^(-1),showing AC values on average 13%lower than expected in a healthy ***,PA and AC were positively *** for sex and age,an increase of 1000 MET-min·week^(-1) was associated with an increase in VO_(2peak) of 0.8 units(95%CI 0.4–1.2;p<0.001).There were no differences in the degree of increase between sexes(p=0.427).Conclusion:These findings suggest that an increase in PA in patients with CHD significantly improves their AC,and hence,could be recommended when the goal is to improve their physical condition.

关键词： Physical activity level aerobic capacity congenital heart disease

Anti-Inflammatory Activity of Ferruginol from Prumnupitys andina

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Journal of Life Sciences 2013年第11期7卷 1165-1169页

作者： maite Rodriguez-Diaz Carlos Areche Carla Delporte Faculty of Medicine Universidad Andres Bello Republiea 330 Santiago 8320000 Chile Department of Chemistry Faculty of Sciences University of Chile Las Palmeras Santiago 8320000 Chile Department of Pharmacological and Toxicological Chemistry Faculty of Chemical and Pharmaceutical Sciences University of Chile Casilla 233 Santiago 8320000 Chile

Ferruginol, a phenolic diterpenoid, was isolated from Prumnupitys andina, a Chilean native plant, as the main compound. Ferruginol has displayed an interesting range of biological activities such as in vitro anti-inflammatory activity. Aim of this research is to evaluate the dermal anti-inflammatory activity of ferruginol, using in vivo models at first time. Ferruginol was subjected to topical assays for the inhibition of inflammation elicited by AA （arachidonic acid） or TPA （phorbol ester） in the murine model. The topical anti-inflammatory activity was evaluated in vivo using groups of 8 animals were treated with a single dose of ferruginol, equimolar doses with regard to the reference drugs, indomethacin and nimesulide. We showed a chemical data were consistent with a type-abietane diterpenoid known as ferruginol. Ferruginol showed topical anti-inflammatory activity at 21.0% and 20.5% in AA and TPA models, respectively. Our results provide data to support further investigations about ferruginol, a type-abietane diterpenoid, as a potential anti-inflammatory agent.

关键词： Ferruginol diterpenes dermal anti-inflammatory activity Prumnupitys andina