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The.Gain Distribution According to the.The.re.ical Structure.and De.ay Dynamics of Sodium like.Cu

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Optics and Photonics Journal 2012年第4期2卷 358-366页

作者： We.same.din S. Abde.aziz mai e. ahmed Ali S. Khalil Mohamme. Alshaik ahmed Tharwat M. e.-She.bini Al-Azhar Unive.sity Gaza Palastine e.vironme.tal Affairs Age.cy Cairo Egypt Laboratory of Lase.s and Ne. Mate.ials Cairo University National Institute.of Lase. e.hance. Se.e.ce. Cairo University Te.in Institute.for Me.rological studie. Helwan Egypt

Le.e. structure. oscillator stre.gths, transition probabilitie. and radiative.life.time. are.e.aluate. for 1s2 2s2 2p63l, 4l, 5l (l = 0, 1, 2, 3, 4) state. in sodium like.Cu18+. The.calculations are.carrie. out using COWAN code. The.calculations we.e.made.are.compare. with othe. re.ults in lite.ature.whe.e.a good agre.me.t is found, we.also re.ort on some.unpublishe. e.e.gy value. and oscillator stre.gths. Our re.ults are.use. in the.calculation of re.uce. population of 21 fine.structure.le.e.s ove. a wide.rang of e.e.tron de.sity value. (1018 to 1020) and at various e.e.tron plasma te.pe.ature. For those.transitions with positive.population inve.sion factor, the.gain coe.ficie.ts are.e.aluate. and plotte. against the.e.e.tron de.sity.

关键词： Le.e. Structure Oscillator Stre.gths Sodium like Cu

e.e.gy Le.e.s, Oscillator Stre.gths, and Transition Probabilitie. of Ni XIX and Cu XX

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Optics and Photonics Journal 2014年第3期4卷 54-89页

作者： We.same.din S. Abde.aziz M. Atta Khe.r mai e. ahmed Laila Gaabour Tharwat e.-Shirbini e.vironme.tal Affairs Age.cy Cairo Egypt Laboratory of Lase.s and Ne. Mate.ials Cairo University Giza Egypt National Institute.of Lase. e.hance. Scie.ce. Cairo University Giza Egypt Physics De.artme.t Faculty of science King Abdul Aziz University Jeddah Saudi Arabia

e.e.gy le.e.s, oscillator stre.gths, and transition probabilitie., for the.1s2 2s2 2p6, 2p53l (l = 0, 1, 2), 2p54l (l = 0, 1, 2, 3) state. in Ni XIX and Cu XX are.calculate. using COWAN code. The.Corre.ation and re.ativistic e.fe.ts are.conside.e.. The.calculations are.compare. with othe. re.ults in the.lite.ature. A good agre.me.t is found. We.also re.ort on some.unpublishe. e.e.gy value..

关键词： e.e.gy Le.e.s Oscillator Stre.gths Transition Probabilitie.

Se.rch for Lase. Line. in Sodium like.Fe.Plasmas

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Optics and Photonics Journal 2012年第4期2卷 314-317页

作者： We.same.din S. Abde.aziz mai e. ahmed Tharwat M. e.-She.bini Mohamme. Alshaik ahmed Ali S. Khalil Al-Azhar Unive.sity in Palastine Ghaza Palastine e.vironme.tal Affairs Age.cy Cairo Egypt Laboratory of Lase.s and Ne. Mate.ials Cairo University Giza Egypt National Institute.of Lase. e.hance. Se.e.ce. Cairo University Giza Egypt 2Environmental Affairs Agency Cairo Egypt Te.in Institute.for Me.rological Studie. (TIMS) Cairo Egypt

e.e.gy le.e.s, transition probabilitie. and e.fe.tive.collision stre.gth for 1s2 2s2 2p6 3l, 4l, 5l (l = 0, 1, 2, 3, 4) state. of sodium like.Fe.are.use. in the.de.e.mination of the.re.uce. populations for 21 fine.structure.le.e.s ove. a wide.rang of e.e.tron de.sity value. (1018 to 1020 cm–3) and at against e.e.tron plasma te.pe.ature.. Gain coe.ficie.ts are.e.aluate. and plotte. against the.e.e.tron de.sity.

关键词： XUV Soft X-Ray Lase. e.ission Gain Coe.ficie.t

Study of scalar particle. through the.Kle.n–Gordon e.uation unde. rainbow gravity e.fe.ts in Bonnor–Me.vin-Lambda space.time

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Communications in The.re.ical Physics 2024年第4期76卷 113-125页

作者： Faizuddin ahmed Abde.male. Bouze.ada De.artme.t of Physics University of Science&Technology MeghalayaRi-Bhoi793101India Laboratory of the.re.ical and applie. Physics Echahid Cheikh Larbi Tebessi UniversityAlgeria

In our inve.tigation,we.e.plore.the.quantum dynamics of charge.fre. scalar particle. through the.Kle.n–Gordon e.uation within the.frame.ork of rainbow gravity,conside.ing the.Bonnor–Me.vin-Lambda(BML)space.time.*** BML solution is characte.ize. by the.magne.ic fie.d stre.gth along the.axis of the.symme.ry dire.tion which is re.ate. to the.cosmological constantΛand the.topological parame.e.αof the.*** be.avior of charge.fre. scalar particle. de.cribe. by the.Kle.n–Gordon e.uation is inve.tigate.,utilizing two se.s of rainbow functions:(i)f(χ)=■,h(χ)=1 and(ii)f(χ)=1,h(χ)=1+βХ/*** 0e.re.re.e.ting the.particle.s e.e.gy,e. is the.Planck's e.e.gy,andβis the.rainbow *** obtain the.approximate.analytical solutions for the.scalar particle. and conduct a thorough analysis of the.obtaine. ***,we.study the.quantum dynamics of quantum oscillator fie.ds within this BML space.time.e.ploying the.Kle.n–Gordon *** also,we.choose.the.same.se.s of rainbow functions and obtain the.approximate.e.ge.value.solution for the.oscillator ***,we.de.onstrate.that the.re.ativistic approximate.e.e.gy profile. of charge.fre. scalar particle. and oscillator fie.ds ge. influe.ce. by the.topology of the.ge.me.ry and the.cosmological ***,we.show that the.e.e.gy profile. of scalar particle. re.e.ve.modifications from the.rainbow parame.e. and the.quantum oscillator fie.ds by both the.rainbow parame.e. and the.fre.ue.cy of oscillation.

关键词： quantum fie.ds in curve. space.time re.ativistic wave.e.uations solutions of wave.e.uations bound-state spe.ial functions

e.act and he.ristic formulae.to compute.the.ge.de.ic he.ght from the.e.lipse.e.uation

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Ge.de.y and Ge.dynamics 2024年第2期15卷 150-155页

作者： Mohame. e.e.che.ahmed Hamdi Mansi Construction De.artme.t Faculty of EngineeringEgyptian Russian UniversityCairoEgypt Istituto Nazionale.di Ge.fisica e.Vulcanologia Sezione di PisaPisaPlItaly

The.conve.sion of the.carte.ian coordinate. of a point to its ge.de.ic e.uivale.t coordinate. in re.e.e.ce.to the.ge.de.ic e.lipsoid is one.of the.main challe.ge. in *** e.lipse.e.uation in the.me.idian plane.significantly influe.ce. the.value.of the.ge.de.ic *** re.e.rch analyze. this influe.ce.and how it can contribute.to the.r *** study inve.tigate. the.mathe.atical re.ation be.we.n the. and pre.e.ts an e.act formula re.ating to the.ge.de.ic he.ght and the.e.lipse.*** addition,a he.ristic formula for the.re.ation be.we.n the.ge.de.ic he.ght and the.e.lipse.e.uation is propose.,which is inde.e.de.t of the.ge.de.ic latitude.and has a re.ative.accuracy be.te. than 99.9 %.The.calculation is stable.and the.cost is low.

关键词： e.lipse.e.uation Ge.de.ic he.ght He.ristic ge.de.ic he.ght

e.gine.ring nanome.icine. for immunoge.ic e.adication of cance. ce.ls:Re.e.t tre.ds and syne.gistic approache.

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Acta Pharmace.tica Sinica B 2024年第6期14卷 2475-2504页

作者： ahmed O.e.zoghby Omar Samir Hagar e.e.am ahmed Soliman Riham M.Abde.galil Yomna M.e.morshe.y Kadria A.e.khodairy Mahmoud L.Nasr Division of e.gine.ring in Me.icine.and Division of Re.al Me.icine Department of MedicineBrigham and Women's HospitalHarvard Medical SchoolBoston 02115MAUSA Cance. Nanote.hnology Re.e.rch Laboratory(CNRL) Faculty of PharmacyAlexandria UniversityAlexandria 21521Egypt

Re.istance.to cance. immunothe.apy is mainly attribute. to poor tumor immunoge.icity as we.l as the.immunosuppre.sive.tumor microe.vironme.t(TMe.le.ding to failure.of immune.*** the.ape.tic strate.ie. including che.othe.apy,radiothe.apy,photodynamic,photothe.mal,magne.ic,che.odynamic,sonodynamic and oncolytic the.apy,have.be.n de.e.ope. to induce.immunoge.ic ce.l de.th(ICD)of cance. ce.ls and the.e.y e.icit immunoge.icity and boost the.antitumor immune.***,many challe.ge. hampe. the.clinical application of ICD induce.s re.ulting in mode.t immunoge.ic ***,we.outline.the.curre.t state.of using nanome.icine. for boosting ICD of cance. ***,syne.gistic approache. use. in combination with ICD inducing nanome.icine. for re.ode.ing the.TMe.via targe.ing immune.che.kpoints,phagocytosis,macrophage.polarization,tumor hypoxia,autophagy and stromal modulation to e.hance.immunoge.icity of dying cance. ce.ls we.e.*** furthe. highlight the.e.e.ging tre.ds of using nanomate.ials for trigge.ing amplifie. ICD-me.iate. antitumor immune.*** re.iculum localize. ICD,focuse. ultrasound hype.the.mia,ce.l me.brane.camouflage. nanome.icine.,amplifie. re.ctive.oxyge. spe.ie.(ROS)ge.e.ation,me.allo-immunothe.apy,ion modulators and e.gine.re. bacte.ia are.among the.most innovative.*** challe.ge.,me.its and de.e.its of ICD induce. nanome.icine. we.e.also discusse. with she.ding light on the.future.role.of this te.hnology in improving the.outcome. of cance. immunothe.apy.

关键词： Immunoge.ic ce.l de.th Immunoge.ic e.adication Nanome.icine. Drug de.ive.y Cance. immunothe.apy Antitumor immunity T ce.ls Tumor associate. antige.s Syne.gistic immune.re.ponse

Diagnostic accuracy of e.OS score.in pre.icting DNR labe.ing afte. ICU admission:A prospe.tive.obse.vational study(e.OS-DNR)

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Journal of Inte.sive.Me.icine 2024年第2期4卷 216-221页

作者： Omar e.Ramadan ahmed F.Mady Mohamme. A.Al-Odat ahmed N.Balshi ahmed W.Ale.re.y Taisy J.Ste.he. She.na R.Diolaso Je.nife. Q.Gano Wale.d Th.Ale.re.y De.artme.t of Critical Care King Saud Medical CityRiyadhSaudi Arabia Ane.the.ia De.artme.t Faculty of MedicineAin Shams UniversityCairoEgypt Ane.the.ia De.artme.t Faculty of MedicineTanta UniversityTantaEgypt Faculty of Me.icine Alexandria UniversityAlexandriaEgypt Nursing De.artme.t King Saud Medical CityRiyadhSaudi Arabia

Background Re.uscitation can some.ime. be.futile.and making a do-not-re.uscitate.DNR)de.ision is in the.be.t inte.e.t of the.*** e.e.tronic poor outcome.scre.ning(e.OS)score.was de.e.ope. to pre.ict 6-month poor outcome. of critically ill *** e.plore. the.diagnostic accuracy of the.e.OS score.in pre.icting DNR de.isions in the.inte.sive.care.unit(ICU).Me.hods This study was conducte. at the.ICU of a te.tiary re.e.ral hospital in Saudi Arabia be.we.n March and May ***,we.calculate. e.OS score. for all e.igible.conse.utive.admissions afte. 48 h in the.ICU and re.orde. the.DNR *** ability of the.score.to pre.ict DNR was e.plore. using logistic ***'s ide.l cut-off value.was calculate. using the.De.ong me.hod,and diffe.e.t diagnostic accuracy me.sure. we.e.ge.e.ate. with corre.ponding 95%confide.ce.inte.vals(CIs).Re.ults We.e.rolle. 857 patie.ts,125 re.e.ve. a DNR orde. and 732 did *** ave.age.e.OS score.of DNR and non-DNR patie.ts was 28.2±10.7 and 15.2±9.7,*** score.as a pre.ictor of DNR orde.,had an are. unde. re.e.ve. ope.ator characte.istic(AUROC)curve.of 81.8%(95%CI:79.0 to 84.3,Pe.'s ide.l cut-off value.17 was associate. with a se.sitivity of 87.2(95%CI:80.0 to 92.5,Pe.ificity of 63.9(95%CI:60.3 to 67.4,Pe.pre.ictive.value.of 29.2(95%CI:24.6 to 33.8,Pe.ative.pre.ictive.value.of 96.7(95%CI:95.1 to 98.3,Pe.e.OS score.pe.forme. we.l as a diagnostic te.t for patie.ts who will be.labe.e. as DNR during the.r ICU stay.A cut-off score.17 may he.p guide.clinical de.isions to withhold or comme.ce.re.uscitative.me.sure..

关键词： Do-not-re.uscitate.DNR) Re.uscitation Inte.sive.care.unit(ICU) Diagnostic accuracy Se.sitivity Spe.ificity

Se.ondary me.abolite. of mulbe.ry le.ve. e.e.t anti-lung cance. activity through re.ulating the.PD-L1/PD-1 signaling pathway

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Journal of Pharmace.tical Analysis 2024年第6期14卷 914-925页

作者： Guiqin Ye.Xin Sun Jiuzhou Li Yuanyuan mai Ruilan Gao Jianbin Zhang Cance. Ce.te. Department of Medical OncologyKey Laboratory of Tumor Molecular Diagnosis and Individualized Medicine of Zhejiang ProvinceZhejiang Provincial People's HospitalAffiliated People's HospitalHangzhou Medical CollegeHangzhou310014China Clinical Laboratory Yuhuan City HospitalTaizhouZhejiang317600China Hangzhou Me.ical Colle.e Hangzhou311300China De.artme.t of Ne.rosurge.y Binzhou People's HospitalBinzhouShandong256600China Institute.of He.atology Re.e.rch The First Affiliated Hospital of Zhejiang Chinese Medical UniversityHangzhou310060China

Lung cance. ranks the.top of malignancie. that cause.cance.-re.ate. de.ths *** le.ve. of Morus alba L are.traditional Chine.e.me.icine.wide.y applie. in re.piratory *** pre.ious work has de.onstrate. the.anti-lung cance. e.fe.t of se.ondary me.abolite. of mulbe.ry le.f,but the.r me.hanism of action has still not fully *** synthe.ize. Moracin N(MAN)-Probe.conjugate. with alkyne.to labe. lung cance. ce.ls and ide.tifie. prote.n targe.s by che.ical prote.mic *** and its probe.e.e.te. similar growth-inhibitory e.fe.t on human lung cance. *** prote.mic re.ults showe. that MAN targe.e. the.programme. de.th ligand 1(PD-L1)che.kpoint pathway and T ce.l re.e.tor(TCR)signaling pathway,indicating its immune.re.ulatory ***-fre. surface.plasmon re.onance.SPR)re.ults showe. the.dire.t inte.action of MAN with PD-L1 *** docking analysis de.onstrate. that MAN bound to e.58 re.idue.of PD-L1 *** downre.ulate. the.e.pre.sion le.e.s of PD-L1 in a time.and dose.de.e.de.t manne. and disrupte. the.PD-L1/programme. de.th 1(PD-1)binding,including othe. se.ondary me.abolite. of mulbe.ry le.ve. Guangsangon e.GSe.and Chalcomoracin(CMR).Human pe.iphe.al blood mononucle.r ce.ls(PBMCs)co-culture. with MAN-tre.te. A549 ce.ls,re.ulting in the.incre.se.of CD8^(+)GZMB^(+)T ce.ls and the.de.re.se.of CD8^(+)PD-1^(+)T *** sugge.te. that MAN e.e.ts anti-cance. e.fe.t through blocking the.PD-L1/PD-1 *** vivo,MAN combine. with anti-PD-1 antibody significantly inhibite. lung cance. de.e.opme.t and me.astasis,indicating the.r syne.gistic *** toge.he.,se.ondary me.abolite. of mulbe.ry le.ve. targe. the.PD-L1/PD-1 signaling,e.hance.T ce.l-me.iate. immunity and inhibit the.tumorige.e.is of lung *** modulatory e.fe.t on tumor microe.vironme.t make. the. able.to e.hance.the.the.ape.tic e.ficacy of immune.che.kpoint inhibitors in lung cance..

关键词： Moracin N Click che.istry PD-L1 T ce.l Lung cance.

Phytoche.ical analysis,antioxidant,ace.ylcholine.te.ase.andα-amylase.inhibitors from Hippe.strum hybridum e.tract

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Journal of Traditional Chine.e.Me.icine 2024年第3期44卷 496-504页

作者： Naila She. Mushtaq ahmed Nadia Mushtaq De.artme.t of Biote.hnology University of Science and Technology Bannu-KPK 28100Pakistan De.artme.t of Botany University of Science and Technology Bannu-KPK 28100Pakistan

OBJe.TIVe.To inve.tigate.the.e.fe.ts of Hippe.strum hybridum(HH)as a fre. radical scave.ge.,and an inhibitor of the.two e.zyme. i-e.Alpha-amylase.α-amylase.and ace.ylcholine.te.ase.AChe..Me.HODS:In this study,HH plant was pre.iminary analyze. for phytoche.ical scre.ning and the. te.te. for its antioxidant,anti-α-amylase.and anti-AChe.e.ficie.cy via standard ***:Phytoche.ical analysis shows the.e.iste.ce.of diffe.e.t compounds;while.Coumarins and quinone. we.e.*** total phe.olic,flavonoid,and tannins conte.t we.e.found to be.78.52±0.69)mg GAe.g,(2.01±0.04)mg RUe.g,and(58.12±0.23)mg TAe.g of plant e.tract re.pe.tive.y.28.02%±0.02%alkaloid and 2.02%±0.05%saponins we.e.pre.e.t in the.HH *** HH e.tract showe. the.anti-oxidant prope.ty with IC50(50%inhibition)of(151.01±0.13)(HH),(79.01±0.04)(Ascorbic acid)for fe.ric re.ucing,(91.48±0.13)(HH),(48.02±0.11)(Ascorbic acid)against Ammonium molybde.um,(156.02±0.31)(HH),(52.38±0.21)(Ascorbic acid)against DPPH,136.01±0.21(HH),52.02±0.31(Ascorbic acid)against H_(2)O_(2),and 154.12±0.03(HH),(40.05±0.15)(Ascorbic acid)μg/mL against ABTS *** analysis indicate. that HH cause. a compe.itive.type.of inhibition ofα-amylase.V_(max)re.0}ne. constant and Km incre.se. from 10.65 to84.37%)while.Glucophage.cause. the.un-compe.itive.type.of inhibition i-e.both Km and V_(max)de.re.se. from40.49 to 69.15%and 38.86 to 69.61%*** K_(i),(inhibition constant);K_(I),(dissociation constant),K_(m),(Michae.is-Me.te. constant),and IC50 we.e.found to be.2,364,68.1,and 38.08±0.22 for HH and 12,101.05,195,34.01±0.21 for ***,HH cause. an anon-compe.itive.type.of inhibition of AChe.i-e.Km re.0}ns constant while.V_(max)de.re.se. from 60.5%to74.1%.The.calculate. K_(i),K_(I),K_(m),and IC50 we.e.found to be.32,36.2,0.05,and 18.117±***:From the.curre.t re.ults,it is conclude. that HH e.tract contains bioactive.compounds,and could be.a good alte.native.to controlling oxidant

关键词： Hippe.strum hybridum phytoche.icals antioxidant alpha-amylase ace.ylcholine.te.ase