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Journal of Otology 2022年第3期17卷 111-115页

作者： Sanjeev Saxena Bhaumik Patel Ravi Roy Himanshu Swami Sanajit Kumar Singh Sunil Goyal Rajeev Chugh Devendra Kumar Gupta Sween Banger mahesh ravanikutty Sneha Yadav Department of ENT World College of Medical Science and ResearchJhajjarHaryanaIndia Department of ENT-HNS Army Hospital Research and ReferralNew DelhiIndia

Objective:To study the potential role of subjective visual vertical(SVV)as a prognostic marker for canalith repositioning maneuver(CRM)in patients with posterior canal benign paroxysmal positional vertigo(PC-BPPV)for the Indian ***:SVV was examined in 30 patients with PC-BPPV before and after canalith repositioning maneuver and after complete resolution of *** parameters included the mean of 10 angular tilt readings and direction of deviation,which were compared before and after CRM and following complete resolution of ***:The angle of SVV tilt was greater and deviated towards the affected ear before CRM in all patients,which decreased significantly shortly after CRM and continued to decrease after complete resolution of PC-BPPV(p<0.0001).Conclusions:SVV can be used to test utricular dysfunction in *** angle of tilt improves in response to CRM,which may be used as a prognostic marker in patients with PC-BPPV receiving CRM.

关键词： Benign paroxysmal positional vertigo(BPPV) Subjective visual vertical(SVV) Otoliths(canaliths) Canalith repositioning maneuver(CRM)

An experimental study on ballistic impact response of jute reinforced polyethylene glycol and nano silica based shear thickening fluid composite

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Defence Technology（防务技术） 2022年第3期18卷 401-409页

作者： Vishwas mahesh Dineshkumar Harursampath Vinyas mahesh NMCAD Lab Department of Aerospace EngineeringIndian Institute of Science(IISc)Bangalore560012KarnatakaIndia Department of Industrial Engineering and Management Siddaganga Institute of Technology KarnatakaTumakuru572102India Department of Mechanical Engineering National Institute of Technology SilcharAssam788010India

The present study aims at assessing the ballistic impact behaviour of jute reinforced polyethylene glycol(PEG)and nano silica based shear thickening fluid(STF).Preparation of STF is achieved by dispersing the nano silica particles at different weight percentage loadings of 10%,20%,30%and 40%in PEG and the effect of various weight percentages loading of nano silica particles on ballistic performance of the proposed composites is studied *** studies of the prepared STF’s showed that at all nanosilica loading shear thickening occurred and also the shear thickening was highest at higher loading of nano silica at lower rate of *** study reveals that the ballistic performance of the jute fabric is enhanced with impregnation of *** ballistic results indicate that energy absorption of the proposed composites is enhanced with increased loading of nano silica particles and at the same time,the effect of STF was *** energy absorption(SEA)of the neat fabric and the proposed composites was made use of for the purpose of comparing the energy absorption *** is found that the SEA of proposed composites with 10%nano silica loading is lesser than the neat fabric both in case of 3 layers and 6 *** was also found that proposed composite with 40%nano silica loading exhibits highest SEA compared to neat fabric and its counterparts with its SEA being 3.21 and 3.76 times highest compared to three and six layers of neat fabrics respectively.

关键词： Ballistic impact Shear thickening fluid Nano silica Jute

Building Resilience Through Disaster Waste Management——UN Environment's Experiences and Approaches

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工程科学与技术 2018年第3期50卷 15-23页

作者： PRADHAN mahesh XU Qing International Environmental Technology Centre United Nations Environment Programme Sichuan Academy of Environmental Sciences

Integrating disaster waste issue is a critical component of making humanitarian action fit for the future,anticipating global risks and challenges such as increased vulnerability due to climate change and environmental *** requires a fundamental shift towards a model that not only strengthens the response to crises but also learns and adapts in order to anticipate and act before such waste *** article conducted analyses on the characteristics of disasters in the past two *** confound disaster waste management,including the timing and magnitude of each disaster,and the amounts and types of waste that will be *** these reasons alone,disaster waste management must be an integral part of development planning and *** 10 years since the 2008 Wenchuan earthquake,this article highlights that disaster waste management is not only debris clearance or waste management following a disaster,but also includes prevention and pre-disaster preparedness aspects in terms of enhancing resilience of local ***"mainstreaming,"ensures that disaster waste management(DWM)will be treated as a priority issue,on an ongoing *** on UN Environment's experiences and approaches,this paper emphasises that preparedness is the key,and that priority should be accorded to integrating disaster contingency planning in national and city level waste management strategies as well as mainstreaming waste management issues within broader disaster preparedness and response plans and *** is envisaged that the issues presented and the gaps identified in this paper will provide a basis for future comprehensive and cohesive research on disaster waste *** turn,this research can lead to better preparedness and response on disaster waste management.

关键词： disaster waste disaster risk reduction waste management Sendai Framework

Hyaluronic acid as a rescue therapy for trinitrobenzene sulfonica cid-induced colitis through Cox-2 and PGE_2 in a Toll-like receptor 4-dependent way

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2011年第9期12卷 712-719页

作者： mahesh MAHASETH Department of Gastroenterology West China Hospital of Sichuan University

We hypothesized whether systemic administration of high-molecular-weight hyaluronic acid(HMW HA) could rescue trinitrobenzene sulfonic acid(TNBS)-induced colitis through Toll-like receptor 4(TLR4) signal.C3H/HeN mice and C3H/HeJ mice were *** were divided into four groups:control,50% ethanol treatment group,TNBS treatment group,and TNBS plus HA treatment *** weight changes,clinical scores,macroscopic scores,and histological scores were *** 2(Cox-2) and prostaglandin E 2(PGE 2) expressions were measured both in colons and peritoneal macrophages from these *** was a rescue therapy for the colitis induced by TNBS only in C3H/HeN *** clinical score,macroscopic score,and histological score were much lower in C3H/HeN mice receiving TNBS plus HA ***-2 and PGE 2 expressions only increased in C3H/HeN *** Cox-2 expressing cells were *** can also promote the production of Cox-2 and PGE 2 in peritoneal macrophages from C3H/HeN *** data demonstrated that HMW HA can rescue TNBS-induced colitis through inducing Cox-2 and PGE 2 expressions in a TLR4-dependent *** may be the effector cells of HMW HA.

关键词： Trinitrobenzene sulfonic acid(TNBS) colitis Therapy Hyaluronic acid Toll-like receptor

Single-atom catalysts boosted ultrathin film sensors

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Rare Metals 2020年第10期39卷 1110-1112页

作者： Rahul Kumar mahesh Kumar Department of Electrical Engineering Indian Institute of Technology JodhpurJodhpur 342037India

Nowadays,demand for fast and accurate detection of toxic and flammable gases is increasing for human health safety,industrial process and environmental ***,gas sensor technology has become a requisite in our daily *** nanoscience and nanotechnology propel fabrication of a gas sensor at the miniaturization level for burgeoning Internet of things applications.

关键词： film nanotechnology gases

The Role of Radical Burst in Plant Defense Responses to Necrotrophic Fungi

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Journal of Integrative Agriculture 2012年第8期11卷 1305-1312页

作者： mahesh S Kulye Key Laboratory of Integrated Pest Management in Crops Ministry of Agriculture/Institute of Plant ProtectionChinese Academy of Agricultural Sciences

Necrotrophic fungi, being the largest class of fungal plant pathogens, pose a serious economic problem to crop production. Nitric oxide （NO） is an essential regulatory molecule in plant immunity in synergy with reactive oxygen species （ROS）. Most experimental data available on the roles of NO and ROS during plant-pathogen interactions are from studies of infections by potential biotrophic pathogens, including bacteria and viruses. However, there are several arguments about the role of ROS in defense responses during plants and necrotrophic pathogens interaction and little is known about the role of NO as a counterpart of ROS in disease resistance to necrotrophic pathogens. This review focuses on the recent knowledge about the role of oxidative burst in plant defense response to necrotrophic fungi.

关键词： nitric oxide mitogen-activated protein kinase necrotrophic fungi programmed cell death reactive oxygen species

Automation in detection of recirculation in a booster fan ventilation network

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International Journal of Mining Science and Technology 2018年第3期28卷 513-517页

作者： mahesh Shriwas Felipe Calizaya Department of Mining Engineering University of Utah

Recirculation is prohibited in many coal mining countries because of the fear that the re-use of return air would allow the build-up of air contaminants at the workings. The incorrect design and location of a booster fan in any ventilation network can create unsafe condition due to recirculation. The current approach to investigating recirculation using simulation software requires manual effort which becomes tedious in a complex and a large network. An algorithm-based C++ program was designed to detect the recirculation in a booster fan ventilation networks. This program needed an input file prepared from output file generated by any ventilation simulator. This program created an output file for recirculation. This program demonstrated the strong capability to detect the recirculation in a sample network and a coal mine ventilation network. The outcomes of this program were documented in this paper.

关键词： Recirculation Ventilation Booster fan

On the application of additive manufacturing methods for auxetic structures: a review

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Advances in Manufacturing 2021年第3期9卷 342-368页

作者： Athul Joseph Vinyas mahesh Dineshkumar Harursampath Nonlinear Multifunctional Composites Analysis and Design(NMCAD)Laboratory Department of Aerospace EngineeringIndian Institute of ScienceBangalore560012India Department of Mechanical Engineering National Institute of TechnologySilcharAssam788010India

Auxetic structures are a special class of structural components that exhibit a negative Poisson’s ratio(NPR)because of their constituent materials,internal microstructure,or structural *** realize such structures,specialized manufacturing processes are required to achieve a dimensional accuracy,reduction of material wastage,and a quicker ***,additive manufacturing(AM)techniques play a pivotal role in this *** is a layer-wise manufacturing process and builds the structure as per the designed geometry with appreciable precision and ***,it is extremely beneficial to fabricate auxetic structures using AM,which is otherwise a tedious and expensive *** this study,a detailed discussion of the various AM techniques used in the fabrication of auxetic structures is *** advancements and advantages put forward by the AM domain have offered a plethora of opportunities for the fabrication and development of unconventional ***,the authors have attempted to provide a meaningful encapsulation and a detailed discussion of the most recent of such advancements pertaining to auxetic *** article opens with a brief history of the growth of auxetic materials and later auxetic ***,discussions centering on the different AM techniques employed for the realization of auxetic structures are *** basic principle,advantages,and disadvantages of these processes are discussed to provide an in-depth understanding of the current level of ***,the performance of some of the prominent auxetic structures realized through these methods is discussed to compare their benefits and *** addition,the influences of geometric and process parameters on such structures are evaluated through a comprehensive review to assess their feasibility for the later-mentioned ***,valuable insights into the applications,limitations,and prospects of AM for auxetic structures

关键词： Auxetic Additive manufacturing(AM) Negative Poisson’s ratio(NPR) Mechanical performance Unit-cell structure

Performance assessment of Alccofine with silica fume,fly ash and slag for development of high strength mortar

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Frontiers of Structural and Civil Engineering 2022年第5期16卷 576-588页

作者： Shivang D.JAYSWAL mahesh MUNGULE Civil Engineering Department Institute of InfrastructureTechnologyResearch and Management(IITRAM)Ahmedabad 380026India

Previous studies on concrete have identified silica fume(SF)as the most effective supplementary material,whereas fly ash(FA)and slag have been identified as economical materials with long term strength *** of blended cement mortar referred to as blended mortar(BM)requires similar *** present study explores the application of Alccofine(AL)as supplementary material and compares its performance with conventional materials namely SF,FA and ground granulated blast furnace slag(GGBS).The mortar specimens with binder to fine-aggregates(b/f)ratio of 1:2 are prepared at water to binder(w/b)ratios of 0.4 and *** strength values and stress-strain curve for control and BM specimens are obtained at 7,28,56,and 90 d curing *** assessment based on strength activity index,k-value method and strength estimation model confirms that AL,despite lower pozzolanic activity,contributes to strength gain,due to reduced dilution *** of stress-strain curves suggests that the effect of w/b ratio is more dominant on the elastic modulus of BM specimens than on control *** observations from the study identify enhanced strength gain,improved elastic modulus and higher energy absorption as key contributions of AL making it a potential supplementary material.

关键词： Alccofine high strength mortar efficiency factor dilution effect

Neuroplasticity, limbic neuroblastosis and neuro-regenerative disorders

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Neural Regeneration Research 2018年第8期13卷 1322-1326页

作者： mahesh Kandasamy Ludwig Aigner Laboratory of Stem Cells and Neuroregeneration Department of Animal Science School of Life Sciences Bharathidasan University Faculty Recharge Programme University Grants Commission (UGC-FRP) Institute of Molecular Regenerative Medicine Salzburg Paracelsus Medical University Spinal Cord Injury and Tissue Regeneration Center Salzburg Paracelsus Medical University

The brain is a dynamic organ of the biological renaissance due to the existence of neuroplasticity. Adult neurogenesis abides by every aspect of neuroplasticity in the intact brain and contributes to neural regeneration in response to brain diseases and injury. The occurrence of adult neurogenesis has unequivocally been witnessed in human subjects, experimental and wildlife research including rodents, bats and cetaceans. Adult neurogenesis is a complex cellular process, in which generation of neuroblasts namely, neuroblastosis appears to be an integral process that occur in the limbic system and basal ganglia in addition to the canonical neurogenic niches. Neuroblastosis can be regulated by various factors and contributes to different functions of the brain. The characteristics and fate of neuroblasts have been found to be different among mammals regardless of their cognitive functions. Recently, regulation of neuroblastosis has been proposed for the sensorimotor interface and regenerative neuroplasticity of the adult brain. Hence, the understanding of adult neurogenesis at the functional level of neuroblasts requires a great scientific attention. Therefore, this mini-review provides a glimpse into the conceptual development of neuroplasticity, discusses the possible role of different types of neuroblasts and signifies neuroregenerative failure as a potential cause of dementia.

关键词： neuroplasticity adult neurogenesis neuroblasts reactive neuroblastosis hippocampus ultrasound neuroregenerative disorders neotrophy echolocation