检索结果-南通市图书馆

Effect of extrusion parameters on degradation of magnesium alloys for bioimplant applications:A review

Transactions of Nonferrous Metals Society of China 2022年第9期32卷 2787-2813页

作者： mahdi shiri Hassan JAFARI Raman SINGH Materials Engineering Department Faculty of Materials Engineering and Interdisciplinary SciencesShahid Rajaee Teacher Training University(SRTTU)16785-136 TehranIran Department of Mechanical&Aerospace Engineering and Department of Chemical Engineering 17 College Walk(Bldg 31)Monash University-Clayton Campus(Melbourne)Vic 3800Australia

Magnesium alloys,as a new generation temporary biomaterial,deserve the desirable biocompatibility and biodegradability,and also contribute to the repair of the damaged bone ***,they do not possess the required corrosion resistance in human body *** mechanical workings,such as extrusion,influence both the mechanical properties and bio-corrosion behavior of magnesium *** review aims to gather information on how the extrusion parameters(extrusion ratio and temperature)influence the bio-corrosion performances of magnesium *** effects are mainly ascribed to the alteration of extruded alloy microstructure,including final grain size and uniformity of grains,texture,and the size,distribution and volume fraction of the second *** recrystallization and grain refinement during extrusion provide a more homogeneous microstructure and cause the formation of basal texture,resulting in improved strength and corrosion resistance of magnesium *** temperature and extrusion ratio are reported as the influential factors in the *** reports reveal that the increase in extrusion ratio and/or the reduction in extrusion temperature cause a decrease in the final grain size,leading to intensification of basal texture,in parallel side of the samples with extrusion line,and to lower volume fraction and size of precipitates in magnesium *** all lead to improving the bio-corrosion resistance of the magnesium alloy implants.

关键词： magnesium alloys extrusion temperature extrusion ratio biodegradation microstructure

来源：

维普期刊数据库

同方期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Antidepressants can treat inflammatory bowel disease through regulation of the nuclear factor-κB/nitric oxide pathway and inhibition of cytokine production:A hypothesis

引用

World Journal of Gastrointestinal Pharmacology and Therapeutics 2012年第6期3卷 83-85页

作者： Hamid Reza Rahimi mahdi shiri Ali Razmi Department of Toxicology and Pharmacology Faculty of Pharmacy and Pharmaceutical Sciences Research Center Tehran University of Medical Sciences Tehran 15614 Iran Pharmacology and Applied Medicine Department of Medicinal Plants Research Center Institute of Medicinal PlantsACECR Karaj 31535 Iran

Inflammatory bowel disease (IBD) is a group of inflammatory disorders mainly affecting the colon and small intestine. The main types of IBD are Crohn’s disease (CD) and ulcerative colitis (UC). UC is restricted to the large intestine whereas CD can affect any part of the gastrointestinal tract. Treating this disorder depends on the form and level of severity. Common treatment involves an anti-inflammatory drug, such as mesalazine, and an immunosuppressant, such as prednisone. Several signaling pathways, including nuclear factor (NF)-κB and nitric oxide (NO), and genetic and environmental factors are believed to play an important role in IBD. Amitriptyline is a commonly used antidepressant with known anti-inflammatory activities. Amitriptyline also acts on the NF-κB/NO pathway or cytokine production. Therefore, we hypothesize that antidepressants like amitriptyline can be pioneered and considered effective as an innovative and effective therapeutic in the treatment and attenuation of development of IBD in adjusted doses.

关键词： Inflammatory bowel disease Crohn’s disease Antidepressant Nuclear factor-κB Nitric oxide

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：