Colorectal cancer(CRC)is a major global cancer burden,ranking third in terms of incidence,but second in terms of mortality[1].Early detection of CRC through screening combined with subsequent removal of polyps remains...
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Colorectal cancer(CRC)is a major global cancer burden,ranking third in terms of incidence,but second in terms of mortality[1].Early detection of CRC through screening combined with subsequent removal of polyps remains a predominant strategy for CRC *** history is a known risk factor for CRC[2-4].However,only a few screening guidelines provide recommendations for individuals with familial CRC risk[5].
Previous studies reported that some plants, including butternut squash, exert positive effects on the brain. However, few studies have examined the effects of butternut squash on learning, memory, and neurogenesis. Th...
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Previous studies reported that some plants, including butternut squash, exert positive effects on the brain. However, few studies have examined the effects of butternut squash on learning, memory, and neurogenesis. This study studied the effects of butternut squash extract on spatial learning and cell proliferation in the dentate gyrus of healthy male rats. Thirty-five male Wistar rats were intraperitoneally injected with 0, 50, 100, 200 and 400 mg/kg butternut squash extract once daily for 2 months. After the last administration, rat's spatial memory was studied using the Morris water maze. Finally, rats were sacrificed and hippocampal sections were prepared for light microscopy and bromodeoxyuridine immunohistochemistry studies. The results revealed that escape latency and swim distance decreased in all treatment groups compared with the control rats, and that the number of bromodeoxyuridine-positive cells in the dentate gyrus was significantly increased in the treatment groups compared with the controls. These findings suggest that butternut squash extract improves the learning and memory abilities of male rats, and increases the proliferation of dentate gyrus cells.
Objective:To investigate the larvicidai activity of essential oil and methanol extract of the Nepeta menthoides(***) against main malaria vector,Anopheles stephensi(An. stephensi).Methods:The essential oil of plan...
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Objective:To investigate the larvicidai activity of essential oil and methanol extract of the Nepeta menthoides(***) against main malaria vector,Anopheles stephensi(An. stephensi).Methods:The essential oil of planl was obtained by Clevenger type apparatus and the methanol extract was supplied with Percolation method,larvicidai activity was tested by WHO *** five fourth-instar larvae of *** were used in the larvicidai assay and four replicates were tested for each *** different concentrations of the oil and extract were tested for calculation of LC50 and LC50 ***:The LC50 and LC90 values were determined by probit ***50 was 69.5 and 234.3 ppm and LC50 was 175.5 and 419.9 ppm for the extract and essential oil ***:According to the results of this study methanolic extract of plant exhibited more larvicidai activity than essential *** could be useful for investigation of new natural larvicidai compounds.
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