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Congenital Disseminated Pyogenic Granuloma:A Case With Numerous Mucocutaneous and Visceral Lesions

Maternal-Fetal Medicine 2024年第3期6卷 190-195页

作者： Siavash Ghaderi-Sohi Behnaz Moradi mahboobeh shirazi Rahil Rahimi Romina Ravanbakhsh Ariana Kariminejad Elham Feizabad Kariminejad-Najmabadi Pathology&Genetics Center Tehran ***Iran Department of Radiology Advanced Diagnostic and Interventional Radiology Research Center(ADIR)Tehran University of Medical SciencesTehran ***Iran Yas Complex Hospital Tehran University of Medical SciencesTehran ***Iran Nikan Hospital Tehran ***Iran

Congenital disseminated pyogenic granuloma(CDPG)is characterized by eruptive disseminated or localized lesions,which may arise spontaneously or secondary to predisposing *** rarer is the occurrence of CDPG with numerous lesions affecting variable organs,which develop during the fetal *** report describes the case of a 32-week-old fetus presenting with severe hydrocephalus and vascular intracranial and right lung masses on magnetic resonance *** labor occurred at the 32^(nd)week due to preterm premature rupture of membranes,and the newborn died due to cardiac dysfunction within 2 hours *** subsequent autopsy revealed multiple violaceous to dark red papules,nodules,pedunculated and un-pedunculated mucocutaneous masses,as well as two brain lesions,a lung lesion,a thoracic wall intramuscular mass,and a pyloric *** examination and immunohistochemical evaluation for glucose transporter 1(GLUT1)confirmed the diagnosis of *** represents a rare condition with an elusive etiology and limited reports in the *** diagnosis from multifocal infantile hemangioma,based on GLUT1 negativity of CDPG,is imperative due to differing clinical course and treatment *** report underscores a severe case of CDPG characterized by preterm labor and demise shortly after delivery,notable for its extensive involvement across multiple organs,including the brain,lung,intestine,musculoskeletal system,mucosal,and numerous cutaneous sites.

关键词： Pyogenic Granuloma Congenital Hemangioma

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