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Prevalence and Factors Associated with Postpartum Depression during the COVID-19 Pandemic among Women in Jeddah, Saudi Arabia: A Cross-Sectional Study

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Open Journal of Obstetrics and Gynecology 2020年第11期10卷 1644-1657页

作者： Aisha Ibrahim Tarabay Dalal Boogis Aysha Tariq Tabbakh Raghad Akram Kemawi Layan Abduljalil Boogis Abdulrahman Tariq Tabbakh maha mohsen al-hadrami Manal mohsen al-hadrami Obstetrics and Gynecology Consultant King Abdulaziz Hospital Jeddah KSA Medical Intern IbnSina College Jeddah KSA Medical Student Battarje Medical College Jeddah KSA Medical Student IbnSina National College Jeddah KSA

Background: Postpartum depression is the most common psychological health problem among females;it begins after the birth of the child and can occur at any time during the first year of delivery. The COVID-19 pandemic is a novel virus that is highly infectious and has several negative psychological impacts on individuals globally. Aim: Coronavirus disease 2019 (COVID-19) has been reported to increase the incidence rate of depression. We investigated the prevalence rate and associated factors of postpartum depression (PPD) among women in Jeddah, Saudi Arabia, during the COVID-19 period, thereby attempting to determine whether and how COVID-19 affected PPD. Methods: This is a cross-sectional study that was conducted on women at one week to six months postpartum using an online questionnaire. SPSS program was used for analyzing data. Results: This study included 150 participated women;49.3% were in the age range of 25 - 34 years old. There were 30.7% reported being primigravida. Regarding the level of depression, there were 60.7% reported the presence of depression;the depression was affected by some demographics of females such as the education level (P = 0.021) and other factors related to the COVID-19 pandemic such as visiting the doctor during

关键词： PPD COVID-19 Prevalence Associated Factors

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Clinical efficacy of direct-acting antiviral therapy for recurrent hepatitis C virus infection after liver transplantation in patients with hepatocellular carcinoma

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World Journal of Hepatology 2020年第9期12卷 628-640页

作者： Mohamed Saleh Ismail Manal Hassan Saira Aijaz Khaderi Wael Ahmed Yousry maha mohsen Kamal El-Din Mohamed Mohamed Bahaa El-Din Osama Aboelfotoh El Sayed Ahmed Omar Kaseb John alan Goss FasihaKanwal Prasun Kumar Jalal Division of Gastroenterology Baylor College of MedicineHoustonTX 77030United States Department of Internal medicine Gastroenterology and HepatologyAin Shams UniversityCairo 11566Egypt Department of Surgery Division of Abdominal TransplantationBaylor College of MedicineHoustonTX 77030United States Department of Epidemiology the University of Texas MD Anderson Cancer CenterHoustonTX 77030United States Department of Surgery Ain Shams UniversityCairo 11566Egypt Department of Gastrointestinal Medical Oncology the University of Texas MD Anderson Cancer CenterHoustonTX 77030United States

BACKGROUND Recurrent hepatitis C virus(HCV)infection of transplanted liver allografts is universal in patients with detectable HCV viremia at the time of ***-acting antiviral(DAA)therapy has been adopted as the standard of care for recurrent HCV infection in the post-transplant ***,there are insufficient data regarding its efficacy in liver transplant(LT)recipients with a history of hepatocellular carcinoma(HCC),and the risk of HCC recurrence after DAA therapy is *** of DAA treatment failure and HCC recurrence in LT *** A total of 106 LT recipients given DAAs for recurrent HCV infection from 2015 to 2019 were identified(68 with and 38 without HCC).Descriptive statistics and logistic regression models were used to estimate the multivariate odds ratios and respective 95%confidence intervals for predictors of treatment failure and HCC *** Six patients(6%)experienced DAA therapy failure post-LT and 100(94%)had a sustained virologic response at follow-up week 12.A high alanine transaminase level>35 U/L at treatment week 4 was a significant predictor of treatment *** to pre-LT DAA therapy is a predictor of post-LT HCC recurrence,P=*** relapse post-LT was also associated with post-transplantation HCC recurrence,P=*** DAAs are effective and safe in the treatment of recurrent HCV infection in LT recipients with history of *** to pre-and post-LT DAA therapy is associated with post-transplantation HCC recurrence.

关键词： Direct-acting antiviral Liver transplant Hepatocellular carcinoma Recurrence

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Differentiated Thyroid Cancer with Thyroglobulin Elevation and Negative Iodine Scintigraphy (TENIS Syndrome)

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International Journal of Otolaryngology and Head & Neck Surgery 2014年第4期3卷 149-153页

作者： Raja Sfar Tarek Kamoun Manel Nouira Hamza Regaieg Nouha Ammar Hela Charfi Achraf Bahloul maha Ben Fredj Kaouther Chatti mohsen Guezguez Habib Essabbah Department of Nuclear Medicine Sahloul Hospital Sousse Tunisia Department of Nuclear Medicine Sahloul Hospital Sousse Tunisia Sousse University Sousse Tunisia University of Monastir Monastir Tunisia Department of Nuclear Medicine Sahloul Hospital Sousse Tunisia

Background and Objectives: Following the initial management, some patients with differentiated thyroid cancer (DTC) develop a state of high thyroglobulin (Tg) and Negative Iodine Scintigraphy. The predisposing factors and outcome of this condition are unclear. In this study, our objectives were to analyze the characteristics of patients with high Tg level and negative Iodine scintigraphy and to determine the predictive factors for development of high Tg and negative scintigraphy. Patients and Methods: Retrospective study of 34 patients undergoing treatment for DTC, followed in the Nuclear Medicine department of the University Hospital—Sahloul Sousse between 1990 and 2006 and having a high Tg and negative Iodine scintigraphy. Fourteen patients had Tg between 2 and 10 ng/ml, 16 had Tg between 11 and 100 ng/ml and 4 patients had Tg more than 100 ng/ml. Results: There were 25 women and 9 men. The mean age was 51.65 years. In 94.1% of cases, the tumor was papillary carcinoma. Follicular tumors accounted for only 5.9%. The mean nodule size was3.26 cm. Capsular invasion was seen in 47.1% cases. The locoregional invasion was found in 35.3%. The lymph node extension was found in 84.8% of patients having lymph node surgery. Lymph node involvement was observed in 92.8% of patients with papillary cancer but it was found in 7.2% of patients with follicular cancers. Lymph node invasion was unilateral in 28.6% (N1a) and bilateral, contralateral or mediastinal in 71.4% (N1b). Initial level of Tg was as follows: 7 patients had Tg between 2 and 10 ng/ml, 14 patients had Tg between 11 and 100 ng/ml and 12 had Tg more than 100 ng/ml. The mean number of radioactive Iodine cure was 11.08 for patients with Tg more than 100 ng/ml with a significant difference (P = 0.001). Conclusion: Among epidemiological, pathological and clinical characteristics, lymph node invasion is the most frequent parameter found in patients with a DTC with high Tg level and negative Iodine scintigraphy.

关键词： Differentiated Thyroid Cancer Thyroglobulin Iodine Scintigraphy TENIS Syndrome

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