检索结果-南通市图书馆

世界核心医学期刊文摘（妇产科学分册） 2006年第12期2卷 43-44页

作者： magtibay p.m. Adams p.B. Silverman m.B. 马超 Division of Gynecologic Oncology Mayo Clinic13400 East Shea BoulevardScottsdaleAZ 85259United States

Objective.:Epithelial ovarian carcinoma with extensive upper abdominal disease may require splenectomy for optimal tumor cytoreduction. We describe patients who required splenectomy during tumor reduction procedures for primary or recurrent epithelial ovarian carcinoma. methods.:Data were abstracted from records of 112 patients who underwent splenectomy as part of primary or secondary cytoreductive surgery. Results.:Of 112 patients,66 had primary and 46 had secondary cytoreduction. Some patients also required bowel resection (50%),formal lymphadenectomy (31%),or urinary tract resection (5%). The most common indications for splenectomy were direct metastatic involvement (46%),facilitation of an en bloc resection of perisplenic disease (41%),and intraoperative trauma (13%). Histologically,65%had hilar involvement; 52%,capsular involvement; and 16%,parenchymal metastases. Short-term complications included wound infections (7),pneumonias (5),thromboembolic events (9),and sepsis (5). Sepsis was associated with an anastomotic bowel leak in 1 patient,with fungal infections in 2 patients (1 pneumonia and 1 pelvic abscess),and with no identifiable infectious source in 2. Two patients required reoperation for bleeding:1 for diffuse intraabdominal bleeding,including the splenic bed,and 1 for pelvic sidewall bleeding. The perioperative mortality rate at splenectomy was 5%:3 from sepsis (1 anastomotic leak,2 pneumonias),2 from pulmonary embolism,and 1 for which the precise cause of death was not ascertainable. The primary cytoreduction group had a median survival of 1.8 years,with an estimated 2-year survival rate of 46%. The median survival in the secondary debulking group was 1.7 years,with an estimated 2-year survival of 42%. Conclusions.:In patients with clinically significant upper abdominal disease,splenectomy as part of primary or secondary cytoreductive surgery is associated with modest morbidity and mortality. The risk-benefit ratio of aggressive surgical cytoreduction

关键词：卵巢癌肿减灭术瘤细胞肿瘤细胞减灭上皮细胞癌淋巴结切除吻合口漏中位生存时间腹部疾病脓

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

卵巢残余综合征

引用

世界核心医学期刊文摘（妇产科学分册） 2006年第8期2卷 8-8页

作者： magtibay p.m. Nyholm J.L. Hernandez J.L. podratz K.C. 党慧敏 Division of Gynecologic Surgery Mayo Clinic 13400 E Shea Blvd Scottsdale AZ 85259 United States Dr.

Objective: This study was undertaken to examine surgical management of patients with ovarian remnant syndrome. Study design: Data were abstracted from records of patients with a history of bilateral salpingo-oophorectomy who were treated surgically at mayo Clinic between 1985 and 2003 for pathologically confirmed residual ovarian tissue. A follow-up questionnaire was also mailed. Results: Records review identified 186 patients (mean age, 37.6 years; mean follow-up, 1.2 years). Of 180 patients with available data, 153 (85% ) underwent oophorectomy by laparotomy, 13 (7% ) by laparoscopy, and 14 (8% ) by transvaginal approach, mostly for endometriosis (56.8% ). Of 186 patients, 105 (57% ) presented with pelvic masses and 89 (48% ) with pelvic pain. Remnant ovarian tissue was associated with a corpus luteum in 78 (42% ) and endometriosis in 54 (29% ). The intraoperative complication rate was 9.6% . Of 142 patients, 12 (9% ) required subsequent re-exploration (1 ovarian remnant identified). Conclusion: This heavily pretreated population has modest risk of bowel, bladder, or ureteral trauma with definitive pelvic sidewall stripping and apical vaginal excision. However, subsequent recurrence is minimal ( more than 90% of patients reported resolution or marked improvement of symptoms.

关键词：卵巢残余综合征盆腔包块子宫内膜异位症卵巢组织输尿管损伤病历回顾腔镜切除卵巢盆腔痛复

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

prevention of postoperative Nausea and Vomiting in Elective Hysterectomy: A prospective, Randomized, placebo Controlled Outcomes Trial of Aprepitant NK-1-Receptor Antagonist

引用

Open Journal of Anesthesiology 2014年第12期4卷 301-307页

作者： Jaime B. Long Luisa Galdi Joseph G. Hentz John B. Leslie paul m. magtibay Rosanne m. C. Kho Jeffrey L. Cornella Javier F. magrina Department of Obstetrics and Gynecology at Reading Health System West Reading USA Department of Biostatistics Mayo Clinic Scottsdale USA Department of Anesthesiology Mayo Clinic Scottsdale USA Department of Gynecologic Surgery Mayo Clinic Scottsdale USA

Objectives: Current prophylactic interventions fail to completely eliminate postoperative nausea and vomiting (pONV) for a substantial number of patients. A new antiemetic (aprepitant) has been effective in preventing chemotherapy induced nausea and vomiting (CINV). We hypothesized that adding aprepitant to our current prophylactic regimen of dexamethasone and ondansetron would reduce the incidence of pONV in our elective hysterectomy population. methods: 256 patients undergoing elective hysterectomy were enrolled in this prospective, randomized, double blinded, placebo controlled trial. Subjects received either oral aprepitant 40 mg or oral placebo 30 minutes prior to induction of standardized anesthesia. The primary outcome was vomiting within the first 24 hours after surgery. postoperative nausea, vomiting, and use of rescue antiemetics were documented over a 24 h period. Additionally, adverse events, hospitalization days, and readmissions for pONV were compared. Results: There was a trend towards reduction of postoperative nausea and vomiting in the aprepitant group. Nausea and vomiting were noted for 24% and 17% of women in the aprepitant group versus 38% and 29% of women in the placebo group, respectively. Supplemental antiemetic medication was used by 42% of women in the aprepitant group versus 60% of women in the placebo group. No adverse events were substantially more common in the aprepitant group than the placebo group. Conclusions: preemptive use of aprepitant prior to elective hysterectomy may reduce the incidence of pONV and diminish the need for rescue antiemetics postoperatively. Further studies with larger power are needed to confirm the trends observed in this study.

关键词： Hysterectomy postoperative Nausea and Vomiting Aprepitant

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：