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A Panorama of the Urological Diseases at the Former Military Teaching Hospital of Cotonou

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Open Journal of Urology（泌尿学期刊） 2023年第5期

作者： Jean Sossa Lionelle Fanou Yao Félicien Hounto Dodji magloire Inès yevi Fred Jean-Martin Hodonou Déjinnin Josué Georges Avakoudjo

Correlation of PSA Level and ISUP Grade Group with Scintigraphic Bone Metastases Detection in 36 Prostate Cancer Patients

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Open Journal of Urology（泌尿学期刊） 2023年第8期

作者： Jean Sossa Lionelle Fanou Adanvo Isaac Houngnigbe Yao Félicien Hounto Dodji magloire Inès yevi Fred Jean-Martin Hodonou Déjinnin Josué Georges Avakoudjo

Survival Rate and Factors Influencing It in Triptorelin-Castrated Metastatic Prostate Cancer Patients

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Open Journal of Urology（泌尿学期刊） 2024年第3期 160页

作者： Sossa Jean Vissoh Gilvias yevi Dodji magloire Inès Hodonou Fred Avakoudjo Déjinnin Josué Georges

Results of an Eight Year Long Practice of Saline Bipolar Transurethral Resection of Prostate

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Open Journal of Urology（泌尿学期刊） 2024年第4期 189页

作者： Sossa Jean Mangoue Moube Ariane Landry yevi Dodji Inès magloire Hodonou Fred Avakoudjo Déjinnin Josué Georges

Klingsor Syndrome: An Observation in a Patient with Schizophrenia

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Open Journal of Urology（泌尿学期刊） 2024年第5期 346页

作者： Mbuya Musapudi Eric Ouake Hadidjatou Michel Agounkpe yevi Dodji magloire Inès Hodonou Fred Martin Avakoudjo Josué Georges Dejinnin

The Impact of Body Mass on Male Fertility in a Cohort of 127 Patients

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Open Journal of Urology 2023年第11期13卷 469-475页

作者： Sossa Jean Fanou Lionelle Kikpadé Joachim Hounto Yao Félicien yevi Dodji magloire Inès Hodonou Fred Martin Avakoudjo Déjinnin Josué Georges Clinique Universitaire d’Urologie-Andrologie Centre National Hospitalier Universitaire Hubert Koutoucou Maga Cotonou Benin

Background: Aromatase and leptin are two adipose tissue cytokines. The former converts androgens into estrogens and stimulates adipogenesis. The latter cannot fully stimulate GnRH release as its hypothalamic receptors are reduced in obese men. Thus, obesity which is associated with an adipose tissue increment can interfere with male fertility. Objective: We aim to study the correlation between the body mass index (BMI) of an individual and the quality of semen he produces. Patients and Method: By means of the software R 4.2.1 we performed a retrospective analysis of the relationship between the BMI and the semen alterations in the patients managed at the former Military Teaching Hospital of Cotonou from October 1, 2017, to September 30, 2022: a bi-varied analysis and Fischer’s exact test (significance threshold 5%, confidence interval 95%) followed by a logistic regression when a non-significant p-value is below 0.20. Results: 127 males managed for infertility (mean age = 36.2 years) were recorded, including 11.1% obese (BMI > 30 kg/m2) and 36.5% overweighted (25 kg/m2 2). The most frequent semen alterations were: oligoasthenospermia (27.8%), asthenospermia (22.2%), oligoasthenoteratospermia (14.3%), azoospermia (13.5%) and asthenoteratospermia (9.5%). Bi-varied analysis showed no correlation between the BMI and the semen alterations (p-value ranged from 0.086 to 0.9) and no difference in semen alterations between patients with BMI below and above 25 kg/m2 (p-value ranged from 0.12 to 0.9). Logistic regression demonstrated that asthenoteratospermia were correlated with BMI ≥ 25 kg/m2 [OR = 2.1, 95% CI (1.50 - 2.70), p = 0.021]. Conclusion: Male obesity and overweight can trigger asthenoteratospermia.

关键词： Body Mass Index Male Infertility Semen Alterations

Prevalence of Comorbidities in the Urological Patients at the Former Military Teaching Hospital of Cotonou

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Open Journal of Urology 2023年第11期13卷 476-483页

作者： Sossa Jean Fanou Lionelle Hounto Yao Félicien yevi Dodji magloire Inès Hodonou Fred Martin Avakoudjo Déjinnin Josué Georges Clinique Universitaire d’Urologie-Andrologie Centre National Hospitalier Universitaire Hubert Koutoucou Maga Cotonou Benin

Background: Comorbidities are additive diseases and care burdens in urological patients. Determining the epidemiologic profile of comorbidities in urological patients in our setting may help us to better the management of urological disease. Objective: To evaluate the prevalence of comorbidities in urological patients. Patient and Method: We collected comorbidity, urological disease and demographic data in all urological patients managed at the former Military Teaching Hospital of Cotonou from January 1, 2012, to December 31, 2020. We used the software R 4.2.2 to perform descriptive and bi-varied data analysis. Student’s t test was used to compare means. Results: The prevalence of comorbidities was 14.2%, i.e., 601 comorbidity-affected among 4242 patients. The comorbidities predominantly affected men: the sex ratio was 13:1. The presence of comorbidity was correlated with patients’ age (p < 0.001). The comorbidities observed in the 601 affected patients were hypertension (84.5%), diabetes (26.5%), asthma (2%), and heart failure (1.2%). Hypertension (p = 0.001) and asthma (p = 0.030) were correlated with age. No comorbidity was associated with gender. The comorbidities’ prevalence was highest in patients aged 40 - 80 years who presented urological diseases such as BPH (68.9%), Erectile dysfunction (ED) and ejaculatory disorders, overactive bladder (OAB) and neurogenic lower urinary tract dysfunction (LUTD), renal cyst (5%), inguinal hernia (4.2%), urinary stones (2.8%), and prostate cancer (2.3%). Conclusion: The comorbidities’ prevalence was 14.2% in the urological patients. The main comorbidities were hypertension (84.5%) and diabetes mellitus (26.5%).

关键词： Comorbidity Urological Patients Prevalence

Clinical Stage Evaluation at Diagnosis of Prostate Cancer at Urology-Andrology Clinic Cnhu-Hkm Cotonou

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Open Journal of Urology 2015年第3期5卷 19-23页

作者： Hounnasso Prince Pascal Avakoudjo Josue Dejinnin Georges Soumanou Fouad Kolawale Yde Koussouhon Manoel Dossavi yevi Dodji magloire Vodonou Alexandre Urology-Andrology Faculty of MedecineCNHU-HKMCotonouBenin Urology-Andrology Faculty of MedicineCHD-OPPorto-NovoBenin

Aims: To evaluate the clinical stage at diagnosis of prostate cancer. Materials and Methods: This study was retrospective and?descriptive from January 2008 to June 2013. Patients who were diagnosed with prostate cancer wereinvolved and confirmed by clinical examination anatomopathological screening. They also realized a total serum PSA, a bladder-prostatic and abdominal ultrasound. Results: Average age was seventy years, ranging from fifty years to seventy years. The general status of our patients was satisfactory in 78% of cases. Main symptoms were dysuria and frequencyin 96% and 86%, respectively. Family past history of prostate cancer were found in 24% of cases. Twenty-three patients (43%) had a total serum PSA ≥ 100 ng/ml. Adenocarcinoma was the main histological type. Grades 1 and 4 were the most frequent. Thirty-three patients (66%) had a Gleasonscore betwen [2]-[6]. Forty-four patients (88%) had locally advanced and metastatic desease. The D’Amico score was identified in six patients but 3 and 2 patients were low risk and intermediate riskrespectively. Finally, 1 patient was high risk. Conclusion: Prostate cancer remains elderly man cancer. It was discovered in locally advanced and metastatic desease in this series. This diagnosis was late in the majority of cases.

关键词： Prostate Cancer Anatomical Pathology Total Serum PSA

Erectile Dysfunction (ED) within Hospital Facilities in Cotonou

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Open Journal of Urology 2017年第3期7卷 65-74页

作者： Natchagande Gilles Avakoudjo Dedjinin Georges Josue yevi Ines Dodji magloire Agounkpe Michel Michael Kaka Mahamane Adama Salissou Sossa Jean Hodonou DetondjiFred Jacquet Djamal Soumanou Fouad Hounnasso Prince Pascal CNHU-HKM Urology-Andrology University Clinic CotonouRepublique of Benin

Introduction: Erectile dysfunction (ED) is defined as the persistent inability to achieve the necessary degree of erection for sexual activity. It is a common disease which can significantly affect the quality of life of sufferer and their partners. The purpose of this study is to give an overview of the magnitude of this medical condition in Benin society. Material and Method: It was a multicenter cross-sectional descriptive and analytical study conducted over a period of one month from 1st to 30th June 2015. A questionnaire was prepared for this purpose. Outcomes: The average age in this series is 48.32 with extremes ranging from 18 to 95 years. These patients were predominantly public servants. All our patients (100% of the study population) responded to the single question of John. B. Mckinlay. The global ED prevalence was 52.6%. The multivariate analysis helped to identify a correlation with several factors associated with ED. These factors included: age, occupation, lifestyle, etc. 41.91% of patients with ED and/or other sexual disorders declared “not at all acceptable” to continue living with these disorders. The patients benefitted from different treatments including IPDE-5 and traditional treatment in respectively 32.8% and 40.1% of cases. Conclusion: ED is a condition in its own which has an impact on the patients’ quality of life. Its discovery may lead to the diagnosis of cardiovascular, hormonal or neurological diseases.

关键词： ED Sexual Disorder Sexuality