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Sjögren’s Syndrome Revealed by Obstructive Renal Failure: A Case Report and Review of the Literature

Open Journal of Nephrology 2022年第4期12卷 375-381页

作者： Mamadou Badou Sanogo aboubacar sidiki Fofana Atabième Kodio Sidy Toure Magara Samake Seydou Sy Alkaya Toure Hamadoun Yattara Saharé Fongoro Nephrology and Hemodialysis Department The Point “G” University Hospital Bamako Mali Nephrology Unit The Fousseyni Daou Hospital Kayes Mali Rheumatology Department The Point “G” University Hospital Bamako Mali National Center for Scientific and Technological Research Bamako Mali Faculty of Medicine and Odontostomatology The University of Science Techniques and Technologies of Bamako Bamako Mali

Introduction: Primary Sjögren’s syndrome (SS) is the most common connective tissue disease after rheumatoid arthritis and affects mostly women between 30 and 40 years of age with an estimated prevalence between 0.1% and 0.6%. This observation illustrates an incidental finding of a case of SS in a young female patient in a context of obstructive renal failure (ARF) due to uterine fibroids. Observation: This was a 31-year-old woman hospitalized for anuric AKI (Acute Kidney Injury) with a creatinine level of 1247 μmol/l. Her history included sickle cell disease A/C and an unoperated uterine fibroid diagnosed 3 years ago. Approximately 2 months before her admission, her symptomatology was made of dizziness, physical asthenia, vomiting, poly-arthralgia, morning rash, pollakiuria and oral dryness. Abdominal examination showed a painless transverse mass in the pelvis. Biological examination showed a CRP (C-reactive protein) level of 488 mg/l. The cytobacteriological examination of the urine was normal and the proteinuria was 1.35 g/24 hours. The CT scan showed kidneys measuring 110 mm on the right and 113 mm on the left associated with bilateral pyelo-caliceal dilatation on a large polymyomatous uterus of interstitial and submucosal type. Immunologically, the anti-nuclear factor, the rheumatoid factor and the anti-SSA antibodies were positive. The resumption of the interrogation within the framework of the research of the subjective dry syndrome to find a notion of intermittent xerophthalmia 4 months ago. The Schirmer test was positive in the left eye. The initial management consisted of a polymyomectomy after 3 sessions of hemodialysis. Background treatment combining prednisone 5 mg/day and methotrexate 20 mg/week was started in parallel with the use of artificial tears. The evolution after twelve (12) months of treatment was favorable with a complete disappearance of the signs dry syndrome and full recovery of renal function. Conclusion: SS can have an insidious evolutio

关键词： Obstructive Renal Failure Fibroid Sjögren’s Syndrome

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Isolated Congestive Reactional Non-Specific Retro-Peritoneal Adenitis Mimicking a Choledocal Cyst in a Case at the “Luxembourg” Hospital Center in Bamako

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Open Journal of Radiology 2022年第4期12卷 189-196页

作者： Camara Mamoudou Camara Toumin Keita aboubacar sidiki Mariko Mahamane Koné Achomba Abdoulaye Konaté Moussa Tounkara Youssouf Sidibé Siaka Center for Medical Imaging Exploration and Diagnosis (CIMED) Conakry Guinea Medical Imaging Department CH Mother-Child “Luxembourg” Bamako Mali Internal Medicine Department of The Siguiri Prefectural Hospital Gamal Abdel Nasser University Conakry Guinea Medical Imaging Department North Franche Comté Hospital Trevenans France Medical Imaging Department CHU Point G Bamako Mali

The aim of our work was to establish the diagnostic difficulty of isolated nonspecific retroperitoneal congestive adenitis on medical imaging. Patient: This is a 27-year-old patient from a district located 660 km from Bamako with no known medical history or notion of travel. The onset of the disease dates back to 3 years marked by pain in the right hypochondrium and the epigastrium radiating to the back in the form of torsion, of medium intensity associated with periodic vomiting and jaundice. She was referred to the medical imaging department for pain in the right hypochondrium and cholestatic jaundice. The abdominal CT scan with and without contrast injection showed an oval retroperitoneal mass, with regular contours sitting behind the head of the pancreas and in front of the right kidney with its hypo-dense center of density equal to 23 HU measuring 44 × 28 mm, with a thick wall enhanced after injection of contrast product. It was associated with a distended gallbladder with a thin wall and hypo-dense content and a moderate dilation of the intrahepatic bile ducts. Following these examinations, the diagnostic hypothesis of cystic dilation of the common bile duct was retained. Surgery made it possible to cure the retroperitoneal lesion, discectomy of the gallbladder and biopsy of the lesions. The histological examination made it possible to make the diagnosis of isolated nonspecific reactive congestive adenitis. Conclusion: Isolated nonspecific congestive retropancreatic adenitis with a necrotic center poses a diagnostic problem for imaging in our environment because of its similarity to the bile duct cyst. This study, which is a very illustrative case, showed us a diagnostic discrepancy between the result of cross-sectional imaging and that of surgery and pathology.

关键词： Adenitis Cyst Imaging Luxembourg

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Ectopic Pelvic Leiomyoma and Diagnostic Difficulty in Imaging: A Case Report from Conakry, Guinea

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Case Reports in Clinical Medicine 2022年第9期11卷 375-379页

作者： Alpha Abdoulaye Balde Mamadou Diallo aboubacar sidiki Keita Thierno Hamidou Balde Adama Kouyate Sekou Traore Ousmane Aminata Bah Faculty of Health Science and Technology UGAN de Conakry Guinea Imaging Department H&ocirc pital Nord Franche Comté Trévenans France Reference Imaging Centre of the Armed Forces (RICA) Conakry Guinea

Introduction: Fibromyomas are benign tumours of frequent uterine location, most often found in black women, whose diagnosis of certainty is histological. The extra uterine location is rare and the physio-pathogenesis is poorly understood. This location poses diagnostic problems on imaging. Management is based on tumour resection. Observation: The authors report a clinical case of a 31-year-old woman who was seen for non-febrile hypogastric pain with a large abdominopelvic mass on physical examination. There was no particular history. The biology did not show any abnormality. Ultrasound with Doppler found a mass that was difficult to characterize, and was completed by a CT scan and a pelvic MRI. The management was surgical with an evolution marked by complications. Conclusion: Ectopic leiomyoma is a rare condition. This location poses diagnostic problems on imaging. Management depends on the type of extra uterine presentation of the myoma.

关键词： Ectopic Histology Imaging Leiomyoma Pelvic

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Prevalence of Severe Anemia (Hb ≤ 5 g/dl) in Non-Dialyzed Chronic Renal Failure Patients in the Nephrology and Hemodialysis Department of Point G University Hospital

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Open Journal of Nephrology 2021年第2期11卷 252-264页

作者： Seydou Sy Magara Samaké aboubacar sidiki Fofana Awa Diallo Moctar Coulibaly Djibril Sy Atabième Kodio Saharé Fongoro Mahamane Kalil Maïga Nephrology Department of Point G University Hospital Bamako Mali Faculty of Medicine of Bamako Bamako Mali Nephrology Unit of the Fousseyni Daou Hospital Kayes Mali Nephrology Unit of Mali Gavardo Hospital Bamako Mali Department of Internal Medicine Point G University Hospital Bamako Mali

Introduction: Chronic renal failure (CRF) is defined as glomerular filtration rate (GFR) less than 60 ml/min/1.73m2 for at least three (3) months. Anemia is one of its most common complications. Anemia increases the risk factor for cardiovascular mortality by 18% per gram of hemoglobin loss. Objectives: To determine the prevalence and characteristics of this severe anemia, to determine the indications for transfusion, the complications related to this anemia, the evolution and the prognosis of these patients. Materials and Methods: This was a descriptive study with retrospective data collection over 18 months (January 1, 2017 to June 30, 2018) that included hospitalized CRF patients. Were included, non-dialyzed chronic renal failure patients with Hb ≤ 5 g/dl hospitalized during the said period. Not included were chronic renal failure patients with an Hb level ≥ 5 g/dl, those followed up and/or hospitalized outside the study period. Results: Among 1176 patients, 26 had severe anemia (Hb level ≤ 5 g/dl) on CRF, a prevalence of 2.21%. The mean age was 40 years ± 32.62 with extremes of 15 and 67 years. Seventeen women and 9 men. The etiology of chronic renal failure (CRF) was hypertensive vascular nephropathy in 50% of cases. CRF was end-stage in 18 patients (69.2%). The mean hemoglobin level was 4.10 g/dl ± 0.64 with extremes of 2 and 5 g/dl. The anemia was microcytic hypochromic in 50% and aregenerative (96.2%). The main symptoms were asthenia in 20 cases (76.9%), dizziness in 20 cases (76.9%), exertional dyspnea in 19 cases (73.1%). Signs of cardiac decompensation (n = 12) were jugular turgor 10 cases (38.5%), hepato-jugular reflux 06 cases (23.1%), mitral insufficiency murmur 06 cases (23.1%). The main complication was left ventricular hypertrophy 17 cases (77.3%). There was no correlation between anemia and sex (p = 0.291), age (p = 0.778), malaria (p = 0.158), etiology of CRF (p = 0.26)

关键词： Severe Anemia Chronic Renal Failure Blood Transfusion Mali

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Pulmonary and Extra-Pulmonary Tuberculosis: Epidemiological and Diagnostic Aspects at Sominé DOLO Hospital in Mopti

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Journal of Tuberculosis Research 2021年第1期9卷 63-71页

作者： Dramane Samake Modibo Coulibaly Mamadou Sayon Keita Mamoutou Dembele aboubacar sidiki Traore Damissa Samuel Coulibaly Oumar Guindo Madou Traore Bakary Sayon Keita Sounkalo Dao Infectious Diseases and Infectious and Tropical Diseases Research Officer Head of Medicine Sominé DOLO Hospital Mopti Mali Laboratory Department of Medical Biology at Sominé DOLO Hospital Mopti Mali Sectorial Unit to Fight HIV/AIDS Tuberculosis and Viral Hepatitis Bamako Mali Department of Medicine at Sominé DOLO Hospital Mopti Mali Department of Medicine at Nianankoro Fomba Hospital Ségou Mali General Director of Sominé DOLO Hospital Mopti Mali Department of Medicine Sikasso Regional Hospital Sikasso Mali Department of Medicine of the Fousseyni Daou Hospital Kayes Mali Head of Infectious Diseases Department at Point G University Hospital Bamako Mali

Despite the efforts made to fight the tuberculosis, Mycobacterium tuberculosis still remains a public health problem, particularly for low-income countries. According to the World Health Organization data, our country, Mali has detected only half of the 10,385 cases of tuberculosis expected for 2014 for a population of 17,309,000 inhabitants. The objective of this present work was to describe the different clinical aspects and the epidemiology of tuberculosis at Hospital Sominé Dolo in Mopti. We performed a retro-prospective and descriptive of tuberculosis cases diagnosed in our department of medicine between May 2016 and August 2018. A total of 96 tuberculosis cases were recorded, i.e. 4.6% and 1.0% for hospitalizations and consultations patterns, respectively. The median of age was 41 with extremes from 5 to 80 years. The age group [31 - 40 years] was the most affected with 20.8%. Men and women were affected in identical proportions, i.e. 50%. Pulmonary locations were the most frequent with 55.2%. Pleural tuberculosis was far the most frequent of the extra-pulmonary forms with 24.0% followed by

关键词： Tuberculosis Clinical Aspects Epidemiology Hospital Sominé DOLO Mopti

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Modified Concrete Using Polyethylene Terephthalate Plastic Waste as a Partial Replacement for Coarse Aggregate

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Open Journal of Applied Sciences 2023年第6期13卷 896-909页

作者： Dodo Kayentao Moussa Tamboura Antoine Padou Diarra Mah Fatoumata Traore Adama Coulibaly aboubacar sidiki Toure Mohamed L. O. Diawara Kélétigui Daou Faculty of Sciences and Techniques (FST) University of Sciences Techniques and Technologies of Bamako Bamako Mali National Research and Experimentation Center for Buildings and Public Works (CNREX-BTP) Bamako Mali National School of Engineering Abderhamane Baba TOURE (ENI-ABT) Bamako Mali

The present work evaluated the properties of modified concrete using polyethylene terephthalate (PET) bottle waste as a partial replacement for coarse aggregate. Modified concrete samples were designed using a water/cement (W/C) ratio of 0.50 and varying percentages of PET replacement (3%, 7%, 10%, and 15% by volume). Dreux Gorisse’s formulation approach was used to make the final products, and the mechanical properties of the samples were determined using Controlab presses. This modified concrete with PET chips has shown that with a 10% replacement of PET chips, the fresh density decreases by 3.56%, and the hardened state density decreases by 2.01%. The water absorption and thermal conductivity of the formulated concretes decreased. However, the results showed that the slump of these fresh concretes increased as the percentage of plastic aggregate replacement increased. Based on the results, incorporating PET aggregates into concrete contributes to good workability, and lightweight concrete structures, and provides some thermal comfort in concrete structures.

关键词： PET Waste Concrete Dreux Gorisse Approach Thermal Conductivity Mechanical Properties of Modified Concrete

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Analysing the Factors Affecting Prenatal Visits in Guinea:A Secondary Study of the 2018 Demographic and Health Survey (DHS)

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Open Journal of Obstetrics and Gynecology（妇产科期刊） 2023年第8期

作者： Abdourahamane Diallo Almamy Amara Toure aboubacar sidiki magassouba Diao Cisse Younoussa Sylla Ibrahima Barry

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Spinal Cord Injuries without Visible Bone Lesions: Analysis of Four Consecutive Cases

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Open Journal of Orthopedics 2018年第3期8卷 95-101页

作者： Magatte Gaye Sarah Ntshindj Mutomb Amadou Ndiasse Kasse N’famara Sylla Sagar Diop Alvin Nah Doe aboubacar sidiki Sangharé Mouhamadou Habib Sy Youssoupha Sakho Department of Neurosurgery Grand-Yoff General Hospital Dakar Senegal Department of Orthopedics and Trauma Surgery Grand-Yoff General Hospital Dakar Senegal

Objectives: Interest of this study is to report four cases of spinal cord injuries without bone lesion. Evolution of the injured patients according to the initial clinic assessment at admission and the treatment performed are discussed. Materials and Methods: From January to December 2016, we performed a retrospective study at the Neurosurgery Department of Hospital General Grand Yoff of Dakar. Four patients were followed for spinal cord injury without visible bone lesions. We analyzed the clinical, radiological, therapeutic and evolutionary data. Trauma caused by stabbing was excluded. Results: In a year, 83 cases of spinal trauma with neurological deficit were hospitalized in the department. Among them, 4 had spinal cord injuries without visible bone lesions. The average age was 31.7 years with extremes ranging from 14 to 47 years. The sex ratio of male/female was 3. We have recorded 2 cases of road traffic accidents, 1 case of fall from height and 1 case of sports accident. On the neurological level, we found 3 cases of tetraplegia, and 1 brachial monoplegia. Computed tomography in all patients was normal. All of them benefited from magnetic resonance imaging that showed spinal cord injury. All patients were under conservative treatment. One patient fully recovered, two partially and one passed away. Conclusion: In presence of any post traumatic myelopathy case, the absence of disco-vertebral lesions should bring to mind the SCIWORA as well as indicate the realization of magnetic resonance imaging.

关键词： Spinal Cord Injuries Trauma MRI

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Epidemiological and Clinical Aspects of Chronic Renal Failure in the Medical Department at the Hospital of Sikasso

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Open Journal of Nephrology 2023年第1期13卷 57-66页

作者： Djénéba Maïga Drissa Goïta Magara Samaké Aboudou Messoum Dolo Yohanna Koné aboubacar sidiki Fofana Seydou Sy Moctar Coulibaly Atabième Kodio Sahdit Baba Coulibaly Saharé Fongoro Nephrology Unit of Sikasso Hospital Sikasso Mali National Center for Scientific and Technological Research (CNRST) Bamako Mali Service de Médecine CHU Mère-Enfant le Luxembourg Bamako Mali Nephrology Unit of the Fousseyni DAOU Hospital Kayes Mali Nephrology and Hemodialysis Service CHU du Point-G Bamako Mali Faculty of Medicine of Bamako Bamako Mali Nephrology Unit of Mali GAVARDO Hospital of Sebenicoro Bamako Mali

Introduction: Chronic renal failure is a real public health problem because of its prevalence, the cost of its management and the high morbidity and mortality rate associated with it. The objective of this study was to determine the frequency, causes and main aggravating factors of chronic renal failure in the medical department of the hospital of Sikasso. Materials and Methods: This was a cross-sectional, retrospective, descriptive study conducted in the medical department of the Sikasso hospital from January 1, 2021 to November 30, 2022. It covered all the records of patients with chronic renal failure hospitalized in the department during this period. The MDRD formula was used to estimate the glomerular filtration rate. The KDIGO 2012 classification was used to stage CKD. Results: Of 820 patient records reviewed, we retained 197 records. The mean age of our patients was 42.25 ± 10 years. The male sex represented 114 (57.9%). The socio-economic level was considered low and precarious in 79.8% of cases. The frequency of chronic renal failure was 24%. The reason for hospitalization was mostly hyper creatinine > 185 μmol/l (92.4%). Herbal medicine was reported in 103 cases (52.3%). Medical history was hypertension 101 cases (51.3%), undocumented gastro duodenal ulcer (UGD) 14 cases (7.6%), hypertension and diabetes 11 cases (5.1%), diabetes 8 cases (4%), lower limb edema 9 cases (4.6%). Hypocalcemia was 147 cases (75.6%) with hyper phosphoremia was 153 cases (77.7%). Hemoglobin level was: <6 g/dl, 44 cases (22.3%);between 6 - 8 g/dl, 77 cases (39.1%), from 8 - 10 g/dl, 54 cases (27.4%). The etiologies of CKD were vascular nephropathy 106 cases (53.8%), interstitial nephropathy, 44 cases (22.3%), glomerular nephropathy, 33 cases (16.8%), diabetic nephropathy, 12 cases (6.1%) and polycystic kidney disease 2 (1%). CKD was classified as stage 5, 171 cases (86.8%), stage 4, 11 cases (5.6%), stage 3, 13 cases (6.6%) and stage 2, 2 cases (1%.) Dialysis was performed in 1095

关键词： Epidemiology Clinical Chronic Renal Failure Sikasso Mali

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First Consultation in Nephrology: Case of the Point G University Hospital (Bamako-Mali)

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Open Journal of Nephrology 2021年第3期11卷 412-421页

作者： Hamadoun Yattara Nouhoum Coulibaly Djeneba Diallo Mamadou Sanogo Seydou Sy Pamela Samiza Moustapha Tanagra Alakay Touré Magara Samaké Sah Dit Baba Coulibaly aboubacar sidiki Fofana Atabieme Kodio Saharé Fongoro Nephrology and Hemodialysis Department of the Point G University Hospital Bamako Mali Nephrology Department of the Regional Hospital of Kayes Kayes Mali

Understanding the first consultation of people with kidney disease seems to us to be essential to understand the attitude of the referring physician and the nephrologist. The aim was to find out to whom a patient with kidney disease should be referred in the first instance and for what reason? Hence the evaluation of the prevalence of the first consultation in the nephrology department of the Point G University Hospital in Bamako was made. Patients and Method: This was a prospective descriptive study which took place from July 2017 to June 2018 in the nephrology department of the Point G University Hospital. The study included all patients who came to the nephrology department for the first time during this period. Results: Between July 2017 and June 2018 at the nephrology and haemodialysis service of the G point University Hospital, we retained 643 out of 1031 patients who came for their first consultation, i.e. 62.36%. There were many patients aged between 41 and 50 years. The average age was 42.6 ± 5.03 years with extremes of 30 and 82 years. The sex ratio (M/F) was in favor of males, 1.14. The majority of patients were referred/evacuated from the referral health centres (57.6%). The majority of patients were referred/evacuated by general practitioners (70.5%). Cardiologists were the main specialists to refer/evacuate patients (21.2%). The main reasons for consultation that led to the first diagnostic hypotheses were: arterial hypertension for vascular nephropathy, glomerular syndrome for glomerular nephropathy, acute uraemia syndrome for acute renal failure, hydronephrosis for obstructive uropathy and finally diabetes for diabetic nephropathy. Conclusion: The first consultation in nephrology remains an important step in the management of renal disease, especially when the referral is an emergency. The percentage of referrals is dominated by general practitioners.

关键词： Renal Failure First Consultation Nephrology CHU du Point G

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